Yap Promotes Noncanonical Wnt Signals from Cardiomyocytes for Heart Regeneration

Cardiac Fibroblast Diversity

(2020) Michelle D. Tallquist   Annual Review of Physiology

Secreted frizzled-related protein 2 prevents pressure-overload-induced cardiac hypertrophy by targeting the Wnt/β-catenin pathway

(2020) Wen-Ying Wei et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Hippo Signaling Plays an Essential Role in Cell State Transitions during Cardiac Fibroblast Development

(2018) Yang Xiao et al.   DEVELOPMENTAL CELL

DKK3 overexpression attenuates cardiac hypertrophy and fibrosis in an angiotensin-perfused animal model by regulating the ADAM17/ACE2 and GSK-3β/β-catenin pathways

(2018) Chun-gang Zhai et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Single-nucleus transcriptomic survey of cell diversity and functional maturation in postnatal mammalian hearts

(2018) Peng Hu et al.   GENES & DEVELOPMENT

Differential Wnt-mediated programming and arrhythmogenesis in right versus left ventricles

(2018) Gang Li et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Hippo pathway in the heart: pivotal roles in development, disease, and regeneration

(2018) Jun Wang et al.   Nature Reviews Cardiology

Canonical and Non-Canonical Wnt Signaling in Immune Cells

(2018) Wook-Jin Chae et al.   TRENDS IN IMMUNOLOGY

Transcriptional integration of mitogenic and mechanical signals by Myc and YAP

(2017) Ottavio Croci et al.   GENES & DEVELOPMENT

Hippo pathway deficiency reverses systolic heart failure after infarction

(2017) John P. Leach et al.   NATURE

Dystrophin–glycoprotein complex sequesters Yap to inhibit cardiomyocyte proliferation

(2017) Yuka Morikawa et al.   NATURE

Blockade to pathological remodeling of infarcted heart tissue using a porcupine antagonist

(2017) Jesung Moon et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genetic lineage tracing defines myofibroblast origin and function in the injured heart

(2016) Onur Kanisicak et al.   Nature Communications

Alternative Wnt Signaling Activates YAP/TAZ

(2015) Hyun Woo Park et al.   CELL

A mouse model for adult cardiac-specific gene deletion with CRISPR/Cas9

(2015) Kelli J. Carroll et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

Actin cytoskeletal remodeling with protrusion formation is essential for heart regeneration in Hippo-deficient mice

(2015) Yuka Morikawa et al.   Science Signaling

YAP/TAZ Incorporation in the β-Catenin Destruction Complex Orchestrates the Wnt Response

(2014) Luca Azzolin et al.   CELL

WLS Retrograde Transport to the Endoplasmic Reticulum during Wnt Secretion

(2014) Jia Yu et al.   DEVELOPMENTAL CELL

Rapid and Pervasive Changes in Genome-wide Enhancer Usage during Mammalian Development

(2013) Alex S. Nord et al.   CELL

Hippo signaling impedes adult heart regeneration

(2013) T. Heallen et al.   DEVELOPMENT

Fibroblasts in myocardial infarction: A role in inflammation and repair

(2013) Arti V. Shinde et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Inactivating mutations of RNF43 confer Wnt dependency in pancreatic ductal adenocarcinoma

(2013) X. Jiang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hippo pathway effector Yap promotes cardiac regeneration

(2013) Mei Xin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A uniform human Wnt expression library reveals a shared secretory pathway and unique signaling activities

(2012) Rani Najdi et al.   DIFFERENTIATION

Restriction of intestinal stem cell expansion and the regenerative response by YAP

(2012) Evan R. Barry et al.   NATURE

The complex world of WNT receptor signalling

(2012) Christof Niehrs   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BMP signaling in congenital heart disease: New developments and future directions

(2011) Jun Wang et al.   BIRTH DEFECTS RESEARCH PART A-CLINICAL AND MOLECULAR TERATOLOGY

Blocking of Frizzled Signaling With a Homologous Peptide Fragment of Wnt3a/Wnt5a Reduces Infarct Expansion and Prevents the Development of Heart Failure After Myocardial Infarction

(2011) Hilde Laeremans et al.   CIRCULATION

Transient Regenerative Potential of the Neonatal Mouse Heart

(2011) E. R. Porrello et al.   SCIENCE

Coordinating developmental signaling: novel roles for the Hippo pathway

(2011) Xaralabos Varelas et al.   TRENDS IN CELL BIOLOGY

The Hippo Pathway Regulates Wnt/β-Catenin Signaling

(2010) Xaralabos Varelas et al.   DEVELOPMENTAL CELL

Ror2/Frizzled Complex Mediates Wnt5a-Induced AP-1 Activation by Regulating Dishevelled Polymerization

(2010) M. Nishita et al.   MOLECULAR AND CELLULAR BIOLOGY

Wnt signal transduction pathways

(2010) Yuko Komiya et al.   Organogenesis

Towards an integrated view of Wnt signaling in development

(2009) R. van Amerongen et al.   DEVELOPMENT

Canonical Wnt signaling is antagonized by noncanonical Wnt5a in hepatocellular carcinoma cells

(2009) Haluk Yuzugullu et al.   Molecular Cancer

Wnt Signaling from Development to Disease: Insights from Model Systems

(2009) K. M. Cadigan et al.   Cold Spring Harbor Perspectives in Biology

Secreted Frizzled-related protein 2 is a procollagen C proteinase enhancer with a role in fibrosis associated with myocardial infarction

(2008) Koichi Kobayashi et al.   NATURE CELL BIOLOGY