Cell sensing and decision-making in confinement: The role of TRPM7 in a tug of war between hydraulic pressure and cross-sectional area

Transition from Actin-Driven to Water-Driven Cell Migration Depends on External Hydraulic Resistance

(2018) Yizeng Li et al.   BIOPHYSICAL JOURNAL

Piezo2 channel regulates RhoA and actin cytoskeleton to promote cell mechanobiological responses

(2018) Carlos Pardo-Pastor et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The TRPV4 channel links calcium influx to DDX3X activity and viral infectivity

(2018) P. Doñate-Macián et al.   Nature Communications

Piezos thrive under pressure: mechanically activated ion channels in health and disease

(2017) Swetha E. Murthy et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Structural determinants of 5′,6′-epoxyeicosatrienoic acid binding to and activation of TRPV4 channel

(2017) Alejandro Berna-Erro et al.   Scientific Reports

The TRPM7 interactome defines a cytoskeletal complex linked to neuroblastoma progression

(2016) Jeroen Middelbeek et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension

(2016) Charles D. Cox et al.   Nature Communications

Perinuclear Arp2/3-driven actin polymerization enables nuclear deformation to facilitate cell migration through complex environments

(2016) Hawa-Racine Thiam et al.   Nature Communications

Active Biochemical Regulation of Cell Volume and a Simple Model of Cell Tension Response

(2015) Jiaxiang Tao et al.   BIOPHYSICAL JOURNAL

Cortical Contractility Triggers a Stochastic Switch to Fast Amoeboid Cell Motility

(2015) Verena Ruprecht et al.   CELL

Confinement and Low Adhesion Induce Fast Amoeboid Migration of Slow Mesenchymal Cells

(2015) Yan-Jun Liu et al.   CELL

Force transmission during adhesion-independent migration

(2015) Martin Bergert et al.   NATURE CELL BIOLOGY

Water Permeation Drives Tumor Cell Migration in Confined Microenvironments

(2014) Kimberly M. Stroka et al.   CELL

Genome engineering using the CRISPR-Cas9 system

(2013) F Ann Ran et al.   Nature Protocols

Biased migration of confined neutrophil-like cells in asymmetric hydraulic environments

(2013) H. V. Prentice-Mott et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Genome-Scale CRISPR-Cas9 Knockout Screening in Human Cells

(2013) Ophir Shalem et al.   SCIENCE

Sphingosine and FTY720 are potent inhibitors of the transient receptor potential melastatin 7 (TRPM7) channels

(2012) Xin Qin et al.   BRITISH JOURNAL OF PHARMACOLOGY

Membrane Tension Maintains Cell Polarity by Confining Signals to the Leading Edge during Neutrophil Migration

(2012) Andrew R. Houk et al.   CELL

Physical confinement alters tumor cell adhesion and migration phenotypes

(2012) Eric M. Balzer et al.   FASEB JOURNAL

Role of Ion Channels and Transporters in Cell Migration

(2012) Albrecht Schwab et al.   PHYSIOLOGICAL REVIEWS

Chemotaxis of Cell Populations through Confined Spaces at Single-Cell Resolution

(2012) ZiQiu Tong et al.   PLoS One

Use the force: membrane tension as an organizer of cell shape and motility

(2012) Alba Diz-Muñoz et al.   TRENDS IN CELL BIOLOGY

Response of chondrocytes to shear stress: antagonistic effects of the binding partners Toll-like receptor 4 and caveolin-1

(2011) Pu Wang et al.   FASEB JOURNAL

Forward Genetic Analysis Reveals Multiple Gating Mechanisms of TRPV4

(2010) Stephen Loukin et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Organizing the cell cortex: the role of ERM proteins

(2010) Richard G. Fehon et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Piezo1 and Piezo2 Are Essential Components of Distinct Mechanically Activated Cation Channels

(2010) B. Coste et al.   SCIENCE

IP3sensitizes TRPV4 channel to the mechano- and osmotransducing messenger 5′-6′-epoxyeicosatrienoic acid

(2008) Jacqueline Fernandes et al.   JOURNAL OF CELL BIOLOGY