The Importance of CXCL1 in Physiology and Noncancerous Diseases of Bone, Bone Marrow, Muscle and the Nervous System

CXCL1: Gene, Promoter, Regulation of Expression, mRNA Stability, Regulation of Activity in the Intercellular Space

(2022) Jan Korbecki et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Cytokines and chemokines multiplex analysis in patients with low disease activity rheumatoid arthritis

(2022) Maria Skrzypkowska et al.   RHEUMATOLOGY INTERNATIONAL

Acute IL-1RA treatment suppresses the peripheral and central inflammatory response to spinal cord injury

(2021) Abi G. Yates et al.   Journal of Neuroinflammation

Chemokines gene expression in the prefrontal cortex of depressed suicide victims and normal control subjects

(2021) Ghanshyam N. Pandey et al.   BRAIN BEHAVIOR AND IMMUNITY

MicroRNA-532-5p protects against cerebral ischemia-reperfusion injury by directly targeting CXCL1

(2021) Yuanyuan Shi et al.   Aging-US

CXCL1-CXCR1/2 signaling is induced in human temporal lobe epilepsy and contributes to seizures in a murine model of acquired epilepsy

(2021) Rossella Di Sapia et al.   NEUROBIOLOGY OF DISEASE

Tick Saliva Protein Evasin-3 Allows for Visualization of Inflammation in Arteries through Interactions with CXC-Type Chemokines Deposited on Activated Endothelium

(2020) Stepan S. Denisov et al.   BIOCONJUGATE CHEMISTRY

Neutrophil-selective deletion of Cxcr2 protects against CNS neurodegeneration in a mouse model of multiple sclerosis

(2020) Yee Ming Khaw et al.   Journal of Neuroinflammation

Chemokines and their Receptors: Multifaceted Roles in Cancer Progression and Potential Value as Cancer Prognostic Markers

(2020) Ha Thi Thu Do et al.   Cancers

MicroRNA-429/Cxcl1 Axis Protective Against Oxygen Glucose Deprivation/Reoxygenation-Induced Injury in Brain Microvascular Endothelial Cells

(2020) Jun Leng et al.   Dose-Response

Participation of CXCL1 in the glial cells during neuropathic pain

(2020) Thamyris Reis Moraes et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Deletion of inflammasome adaptor protein ASC enhances functional recovery after spinal cord injury in mice

(2020) Yasuyuki Shiraishi et al.   JOURNAL OF ORTHOPAEDIC SCIENCE

Herpes Simplex Virus-1 in the Brain: The Dark Side of a Sneaky Infection

(2020) Maria Elena Marcocci et al.   TRENDS IN MICROBIOLOGY

Neutrophils: Underestimated Players in the Pathogenesis of Multiple Sclerosis (MS)

(2020) Mirre De Bondt et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

NLRP1 inflammasome contributes to chronic stress-induced depressive-like behaviors in mice

(2020) Ao-Qi Song et al.   Journal of Neuroinflammation

Stroke

(2020) Bruce C V Campbell et al.   LANCET

The CSF Levels of Neutrophil‐Related Chemokines in Patients with Neuromyelitis Optica

(2020) Zhuhe Liu et al.   Annals of Clinical and Translational Neurology

West Nile Virus: An Update on Pathobiology, Epidemiology, Diagnostics, Control and “One Health” Implications

(2020) Gervais Habarugira et al.   Pathogens

Understanding the Role of Interleukin-6 (IL-6) in the Joint and Beyond: A Comprehensive Review of IL-6 Inhibition for the Management of Rheumatoid Arthritis

(2020) Ennio G. Favalli   Rheumatology and Therapy

Cytokines CCL2 and CXCL1 may be potential novel predictors of early bone loss

(2020) Yaqian Hu et al.   Molecular Medicine Reports

Astrocyte- and Neuron-Derived CXCL1 Drives Neutrophil Transmigration and Blood-Brain Barrier Permeability in Viral Encephalitis

(2020) Benedict D. Michael et al.   Cell Reports

Neuromyelitis optica

(2020) Sven Jarius et al.   Nature Reviews Disease Primers

Mechanically stimulated osteocytes promote the proliferation and migration of breast cancer cells via a potential CXCL1/2 mechanism

(2020) Anushree Dwivedi et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Neuroinflammation, Microglia, and Cell-Association during Prion Disease

(2019) James Carroll et al.   Viruses-Basel

Neutrophils in Rheumatoid Arthritis: Breaking Immune Tolerance and Fueling Disease

(2019) Liam J. O’Neil et al.   TRENDS IN MOLECULAR MEDICINE

Epilepsy in adults

(2019) Roland D Thijs et al.   LANCET

Chemokine‐triggered microtubule polymerization promotes neutrophil chemotaxis and invasion but not transendothelial migration

(2019) Sandeep Kumar Yadav et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The neutrophil-to-lymphocyte and monocyte-to-lymphocyte ratios are independently associated with neurological disability and brain atrophy in multiple sclerosis

(2019) Christopher C. Hemond et al.   BMC Neurology

Tick-borne encephalitis in Europe and Russia: Review of pathogenesis, clinical features, therapy, and vaccines

(2019) Daniel Ruzek et al.   ANTIVIRAL RESEARCH

CXCL1 promotes the proliferation of neural stem cells by stimulating the generation of reactive oxygen species in APP/PS1 mice

(2019) Yu Shang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Reduced CXCL1/GRO chemokine plasma levels are a possible biomarker of elderly depression

(2019) Giuseppe Fanelli et al.   JOURNAL OF AFFECTIVE DISORDERS

Cathepsin E in neutrophils contributes to the generation of neuropathic pain in experimental autoimmune encephalomyelitis

(2019) Yuka Harada et al.   PAIN

Bioinformatics Analysis of Gene Expression Profiles of Sex Differences in Ischemic Stroke

(2019) Wenhao Zhu et al.   Biomed Research International

Etiology is the key determinant of neuroinflammation in epilepsy: Elevation of cerebrospinal fluid cytokines and chemokines in febrile infection‐related epilepsy syndrome and febrile status epilepticus

(2019) Kavitha Kothur et al.   EPILEPSIA

A knottin scaffold directs the CXC-chemokine–binding specificity of tick evasins

(2019) Angela W. Lee et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CXCL1 and CXCL2 Inhibit the Axon Outgrowth in a Time- and Cell-Type-Dependent Manner in Adult Rat Dorsal Root Ganglia Neurons

(2019) Antonia Teona Deftu et al.   NEUROCHEMICAL RESEARCH

CXCR2 expression on granulocyte and macrophage progenitors under tumor conditions contributes to mo-MDSC generation via SAP18/ERK/STAT3

(2019) Xiaoqing Han et al.   Cell Death & Disease

The Neutrophil-to-Lymphocyte Ratio is Related to Disease Activity in Relapsing Remitting Multiple Sclerosis

(2019) D’Amico et al.   Cells

Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis

(2019) Xiu-xiu Liu et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Changes in cytokine and chemokine profiles in mouse serum and brain, and in human neural cells, upon tick-borne encephalitis virus infection

(2019) Petra Pokorna Formanova et al.   Journal of Neuroinflammation

Cytokine and immune cell profiling in the cerebrospinal fluid of patients with neuro-inflammatory diseases

(2019) Gildas Lepennetier et al.   Journal of Neuroinflammation

IL-8 Released from Human Pancreatic Cancer and Tumor-Associated Stromal Cells Signals through a CXCR2-ERK1/2 Axis to Induce Muscle Atrophy

(2019) Chandler S. Callaway et al.   Cancers

Tumor-derived cytokines impair myogenesis and alter the skeletal muscle immune microenvironment

(2018) Kelly A. Hogan et al.   CYTOKINE

Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment

(2018) Jonathan J. Grist et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

A guide to chemokines and their receptors

(2018) Catherine E. Hughes et al.   FEBS Journal

Inflammatory markers as predictors of depression and anxiety in adolescents: Statistical model building with component-wise gradient boosting

(2018) Consuelo Walss-Bass et al.   JOURNAL OF AFFECTIVE DISORDERS

The intrathecal expression and pathogenetic role of Th17 cytokines and CXCR2-binding chemokines in tick-borne encephalitis

(2018) Sambor Grygorczuk et al.   Journal of Neuroinflammation

IL-17-receptor-associated adaptor Act1 directly stabilizes mRNAs to mediate IL-17 inflammatory signaling

(2018) Tomasz Herjan et al.   NATURE IMMUNOLOGY

Anti-nociceptive Role of CXCL1 in a Murine Model of Peripheral Nerve Injury-induced Neuropathic Pain

(2018) Ling Cao et al.   NEUROSCIENCE

Increase in chemokine CXCL1 by ERβ ligand treatment is a key mediator in promoting axon myelination

(2018) Hawra Karim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hallmarks of Cellular Senescence

(2018) Alejandra Hernandez-Segura et al.   TRENDS IN CELL BIOLOGY

CXCL1 and CXCL2 produced by tumor promote the generation of monocytic myeloid-derived suppressor cells

(2018) Huifang Shi et al.   CANCER SCIENCE

Inflammation-induced Gro1 triggers senescence in neuronal progenitors: effects of estradiol

(2018) Svetlana Zonis et al.   Journal of Neuroinflammation

The epidemiology of obesity

(2018) Yu Chung Chooi et al.   METABOLISM-CLINICAL AND EXPERIMENTAL

Astragaloside IV Promotes Adult Neurogenesis in Hippocampal Dentate Gyrus of Mouse through CXCL1/CXCR2 Signaling

(2018) Fei Huang et al.   MOLECULES

Cellular and Molecular Mechanisms of Prion Disease

(2018) Christina J. Sigurdson et al.   Annual Review of Pathology-Mechanisms of Disease

Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis

(2018) Tamara Girbl et al.   IMMUNITY

Depression

(2018) Gin S Malhi et al.   LANCET

Innate Immune Response of Primary Human Keratinocytes to West Nile Virus Infection and Its Modulation by Mosquito Saliva

(2018) Magali Garcia et al.   Frontiers in Cellular and Infection Microbiology

Effect of CXCR2 Inhibition on Behavioral Outcomes and Pathology in Rat Model of Neuromyelitis Optica

(2018) Melina V. Jones et al.   Journal of Immunology Research

Alzheimer's disease

(2017) C. A. Lane et al.   EUROPEAN JOURNAL OF NEUROLOGY

Characterization of the early local immune response toIxodes ricinustick bites in human skin

(2017) Martin Glatz et al.   EXPERIMENTAL DERMATOLOGY

Ticks from diverse genera encode chemokine-inhibitory evasin proteins

(2017) Jenni Hayward et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Microglia-derived IL-1β promotes chemokine expression by Müller cells and RPE in focal retinal degeneration

(2017) Riccardo Natoli et al.   Molecular Neurodegeneration

The chemokine receptor CXCR2 supports nociceptive sensitization after traumatic brain injury

(2017) De-Yong Liang et al.   Molecular Pain

Chemokines in depression in health and in inflammatory illness: a systematic review and meta-analysis

(2017) S P Leighton et al.   MOLECULAR PSYCHIATRY

GROα overexpression drives cell migration and invasion in triple negative breast cancer cells

(2017) Kruttika Bhat et al.   ONCOLOGY REPORTS

CAF-secreted CXCL1 conferred radioresistance by regulating DNA damage response in a ROS-dependent manner in esophageal squamous cell carcinoma

(2017) Hongfang Zhang et al.   Cell Death & Disease

Elevated Levels of Proinflammatory Cytokines in Cerebrospinal Fluid of Multiple Sclerosis Patients

(2017) Timur Khaibullin et al.   Frontiers in Immunology

Osteopontin facilitates West Nile virus neuroinvasion via neutrophil “Trojan horse” transport

(2017) Amber M. Paul et al.   Scientific Reports

CXCR2 and CXCL4 regulate survival and self-renewal of hematopoietic stem/progenitor cells

(2016) A. Sinclair et al.   BLOOD

RelA regulates CXCL1/CXCR2-dependent oncogene-induced senescence in murine Kras-driven pancreatic carcinogenesis

(2016) Marina Lesina et al.   JOURNAL OF CLINICAL INVESTIGATION

Rheumatoid arthritis

(2016) Josef S Smolen et al.   LANCET

Epidemiology of Multiple Sclerosis

(2016) Jonathan Howard et al.   NEUROLOGIC CLINICS

Marrow adipocyte-derived CXCL1 and CXCL2 contribute to osteolysis in metastatic prostate cancer

(2015) Aimalie L. Hardaway et al.   CLINICAL & EXPERIMENTAL METASTASIS

NLRP3 Inflammasome Mediates Chronic Mild Stress-Induced Depression in Mice via Neuroinflammation

(2015) Y. Zhang et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

Neutrophil-related factors as biomarkers in EAE and MS

(2015) Julie M. Rumble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Astrocytes Are Primed by Chronic Neurodegeneration to Produce Exaggerated Chemokine and Cell Infiltration Responses to Acute Stimulation with the Cytokines IL-1  and TNF- 

(2015) E. Hennessy et al.   JOURNAL OF NEUROSCIENCE

Adiponectin induces CXCL1 secretion from cancer cells and promotes tumor angiogenesis by inducing stromal fibroblast senescence

(2015) Lun Cai et al.   MOLECULAR CARCINOGENESIS

Serum proteomic profiling of major depressive disorder

(2015) M Bot et al.   Translational Psychiatry

An update on immunopathogenesis, diagnosis, and treatment of multiple sclerosis

(2015) Neeta Garg et al.   Brain and Behavior

Anti-inflammatory mechanisms of IFN-γ studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis

(2015) Nichole M. Miller et al.   Frontiers in Neuroscience

Chemokine CXCL1 enhances inflammatory pain and increases NMDA receptor activity and COX-2 expression in spinal cord neurons via activation of CXCR2

(2014) De-Li Cao et al.   EXPERIMENTAL NEUROLOGY

Neuromyelitis optica IgG stimulates an immunological response in rat astrocyte cultures

(2014) Charles L. Howe et al.   GLIA

Integrative transcriptomic and proteomic analysis of osteocytic cells exposed to fluid flow reveals novel mechano-sensitive signaling pathways

(2014) Peter M. Govey et al.   JOURNAL OF BIOMECHANICS

Dynamics of Immune Cell Recruitment during West Nile Encephalitis and Identification of a New CD19+B220-BST-2+ Leukocyte Population

(2014) A.-C. Brehin et al.   JOURNAL OF IMMUNOLOGY

Cutting Edge: Critical Role for Mesothelial Cells in Necrosis-Induced Inflammation through the Recognition of IL-1  Released from Dying Cells

(2014) T. Eigenbrod et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Regulated Neutrophil Recruitment Is Required for Brain but Not Spinal Cord Inflammation during Experimental Autoimmune Encephalomyelitis

(2014) Sarah B. Simmons et al.   JOURNAL OF IMMUNOLOGY

CXCL1 but Not IL-6 Is Required for Recurrent Herpetic Stromal Keratitis

(2014) D. M. West et al.   JOURNAL OF IMMUNOLOGY

The cerebrospinal fluid cytokine signature of multiple sclerosis: A homogenous response that does not conform to the Th1/Th2/Th17 convention

(2014) Joachim Burman et al.   JOURNAL OF NEUROIMMUNOLOGY

Activation of Intrinsic Immune Responses and Microglial Phagocytosis in an Ex Vivo Spinal Cord Slice Culture Model of West Nile Virus Infection

(2014) E. D. Quick et al.   JOURNAL OF VIROLOGY

Interactions between Neutrophils, Th17 Cells, and Chemokines during the Initiation of Experimental Model of Multiple Sclerosis

(2014) Dagmara Weronika Wojkowska et al.   MEDIATORS OF INFLAMMATION

Secretome Analysis of an Osteogenic Prostate Tumor Identifies Complex Signaling Networks Mediating Cross-talk of Cancer and Stromal Cells Within the Tumor Microenvironment

(2014) Yu-Chen Lee et al.   MOLECULAR & CELLULAR PROTEOMICS

IL-17 and Glutamate Excitotoxicity in the Pathogenesis of Multiple Sclerosis

(2014) M. Kostic et al.   SCANDINAVIAN JOURNAL OF IMMUNOLOGY

TNFαPromotes Th17 Cell Differentiation through IL-6 and IL-1βProduced by Monocytes in Rheumatoid Arthritis

(2014) Yingxia Zheng et al.   Journal of Immunology Research

Chemokine receptor CXCR2 is transactivated by p53 and induces p38-mediated cellular senescence in response to DNA damage

(2013) Haiyang Guo et al.   AGING CELL

Identification of PTHrP(12-48) as a Plasma Biomarker Associated with Breast Cancer Bone Metastasis

(2013) C. L. Washam et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Effect of Myostatin on Chemokine Expression in Regenerating Skeletal Muscle Cells

(2013) Shunsuke Iwasaki et al.   CELLS TISSUES ORGANS

Functional defect of peripheral neutrophils in mice with induced deletion of CXCR2

(2013) LiPing Liu et al.   GENESIS

I B  is a regulator of the senescence-associated secretory phenotype in DNA damage- and oncogene-induced senescence

(2013) E. Alexander et al.   JOURNAL OF CELL SCIENCE

HuR Is Required for IL-17-Induced Act1-Mediated CXCL1 and CXCL5 mRNA Stabilization

(2013) T. Herjan et al.   JOURNAL OF IMMUNOLOGY

Saturated fatty acid palmitate-induced insulin resistance is accompanied with myotube loss and the impaired expression of health benefit myokine genes in C2C12 myotubes

(2013) Ming Yang et al.   Lipids in Health and Disease

Fas/CD95-Induced Chemokines Can Serve as “Find-Me” Signals for Apoptotic Cells

(2013) Sean P. Cullen et al.   MOLECULAR CELL

Act1 mediates IL-17–induced EAE pathogenesis selectively in NG2+ glial cells

(2013) Zizhen Kang et al.   NATURE NEUROSCIENCE

Temporal expression profile of CXC chemokines in serum of patients with spinal cord injury

(2013) Gholamhossein Hassanshahi et al.   NEUROCHEMISTRY INTERNATIONAL

The role of keratinocyte-derived chemokine (KC) on hyperalgesia caused by peripheral nerve injury in mice

(2013) Marianne Neves Manjavachi et al.   NEUROPHARMACOLOGY

Chemokine contribution to neuropathic pain: Respective induction of CXCL1 and CXCR2 in spinal cord astrocytes and neurons

(2013) Zhi-Jun Zhang et al.   PAIN

CXCL1 Contributes to β-Amyloid-Induced Transendothelial Migration of Monocytes in Alzheimer’s Disease

(2013) Ke Zhang et al.   PLoS One

Chemokines induce axon outgrowth downstream of Hepatocyte Growth Factor and TCF/β-catenin signaling

(2013) Deepshikha Bhardwaj et al.   Frontiers in Cellular Neuroscience

Tick salivary compounds: their role in modulation of host defences and pathogen transmission

(2013) Mária Kazimírová et al.   Frontiers in Cellular and Infection Microbiology

Muscle-derived expression of the chemokine CXCL1 attenuates diet-induced obesity and improves fatty acid oxidation in the muscle

(2012) Line Pedersen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

(2012) M. Gelderblom et al.   BLOOD

Characterization of contraction-induced IL-6 up-regulation using contractile C2C12 myotubes

(2012) Arta Farmawati et al.   ENDOCRINE JOURNAL

Neutrophils recruited by CXCR1/2 signalling mediate post-incisional pain

(2012) E.U. Carreira et al.   EUROPEAN JOURNAL OF PAIN

CXCL1 regulation of oligodendrocyte progenitor cell migration is independent of calcium signaling

(2012) Parvez Vora et al.   EXPERIMENTAL NEUROLOGY

Systematic classification of vertebrate chemokines based on conserved synteny and evolutionary history

(2012) Hisayuki Nomiyama et al.   GENES TO CELLS

Association of CXCL1 promoter polymorphism with ischaemic stroke in Korean population

(2012) H. J. Park et al.   International Journal of Immunogenetics

IL-17A Differentially Regulates Corneal Vascular Endothelial Growth Factor (VEGF)-A and Soluble VEGF Receptor 1 Expression and Promotes Corneal Angiogenesis after Herpes Simplex Virus Infection

(2012) A. Suryawanshi et al.   JOURNAL OF IMMUNOLOGY

Early Cytokine Elevation, PrPres Deposition, and Gliosis in Mouse Scrapie: No Effect on Disease by Deletion of Cytokine Genes IL-12p40 and IL-12p35

(2012) D. Tribouillard-Tanvier et al.   JOURNAL OF VIROLOGY

IFN-γ-induced apoptosis of human embryonic stem cell derived oligodendrocyte progenitor cells is restricted by CXCR2 signaling

(2012) Emanuele Tirotta et al.   Stem Cell Research

Increased function of the TRPV1 channel in small sensory neurons after local inflammation or in vitro exposure to the pro-inflammatory cytokine GRO/KC

(2012) Fei Dong et al.   Neuroscience Bulletin

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

Control of the senescence-associated secretory phenotype by NF- B promotes senescence and enhances chemosensitivity

(2011) Y. Chien et al.   GENES & DEVELOPMENT

CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis

(2011) Emanuele Tirotta et al.   GLIA

Exercise-induced liver chemokine CXCL-1 expression is linked to muscle-derived interleukin-6 expression

(2011) Line Pedersen et al.   JOURNAL OF PHYSIOLOGY-LONDON

Senescence surveillance of pre-malignant hepatocytes limits liver cancer development

(2011) Tae-Won Kang et al.   NATURE

Treatment with IL-17 prolongs the half-life of chemokine CXCL1 mRNA via the adaptor TRAF5 and the splicing-regulatory factor SF2 (ASF)

(2011) Dongxu Sun et al.   NATURE IMMUNOLOGY

Multiplexed Immunoassay Panel Identifies Novel CSF Biomarkers for Alzheimer's Disease Diagnosis and Prognosis

(2011) Rebecca Craig-Schapiro et al.   PLoS One

Duffy Antigen Receptor for Chemokines Mediates Chemokine Endocytosis through a Macropinocytosis-Like Process in Endothelial Cells

(2011) Yani Zhao et al.   PLoS One

Sickness behaviour is induced by a peripheral CXC-chemokine also expressed in Multiple Sclerosis and EAE

(2010) Sandra J. Campbell et al.   BRAIN BEHAVIOR AND IMMUNITY

Chemokine-related gene expression in the brain following ischemic stroke: No role for CXCR2 in outcome

(2010) Vanessa H. Brait et al.   BRAIN RESEARCH

Depletion of CXCR2 inhibits γ-secretase activity and amyloid-β production in a murine model of Alzheimer’s disease

(2010) Pancham Bakshi et al.   CYTOKINE

The chemokine CXCL1 induces proliferation in epithelial ovarian cancer cells by transactivation of the epidermal growth factor receptor

(2010) Christine Bolitho et al.   ENDOCRINE-RELATED CANCER

Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema

(2010) Yuka Ikegame et al.   HYPERTENSION RESEARCH

A Paradoxical Role for Neutrophils in the Pathogenesis of West Nile Virus

(2010) Fengwei Bai et al.   JOURNAL OF INFECTIOUS DISEASES

Characterization of contraction-inducible CXC chemokines and their roles in C2C12 myocytes

(2009) Taku Nedachi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Structural optimization of a CXCR2-directed antagonist that indirectly inhibits γ-secretase and reduces Aβ

(2009) Pancham Bakshi et al.   BIOORGANIC & MEDICINAL CHEMISTRY

The Chemokine Cxcl1 Is a Novel Target Gene of Parathyroid Hormone (PTH)/PTH-Related Protein in Committed Osteoblasts

(2009) Döne Onan et al.   ENDOCRINOLOGY

The effects of the selective and non-peptide CXCR2 receptor antagonist SB225002 on acute and long-lasting models of nociception in mice

(2009) Marianne N. Manjavachi et al.   EUROPEAN JOURNAL OF PAIN

Inhibition of CXCR2 signaling promotes recovery in models of multiple sclerosis

(2009) A.E. Kerstetter et al.   EXPERIMENTAL NEUROLOGY

Analysis of Protein Levels of 24 Cytokines in Scrapie Agent-Infected Brain and Glial Cell Cultures from Mice Differing in Prion Protein Expression Levels

(2009) D. Tribouillard-Tanvier et al.   JOURNAL OF VIROLOGY

Chemokines direct neural progenitor cell migration following striatal cell loss

(2009) Renee J. Gordon et al.   MOLECULAR AND CELLULAR NEUROSCIENCE

NF-κB Mediated Enhancement of Potassium Currents by the Chemokine CXCL1/Growth Related Oncogene in Small Diameter Rat Sensory Neurons

(2009) Rui-Hua Yang et al.   Molecular Pain

Simultaneous measurement of 23 plasma cytokines in late-life depression

(2009) Kang Soo Lee et al.   NEUROLOGICAL SCIENCES

Alterations of the CD4+, CD8+ T Cell Subsets, Interleukins-1β, IL-10, IL-17, Tumor Necrosis Factor-α and Soluble Intercellular Adhesion Molecule-1 in Rheumatoid Arthritis and Osteoarthritis: Preliminary Observations

(2009) Mahmoud R. Hussein et al.   PATHOLOGY & ONCOLOGY RESEARCH

Novel Role of CXCR2 in Regulation of γ-Secretase Activity

(2008) Pancham Bakshi et al.   ACS Chemical Biology

Neuroprotection and Remyelination after Autoimmune Demyelination in Mice that Inducibly Overexpress CXCL1

(2008) Kakuri M. Omari et al.   AMERICAN JOURNAL OF PATHOLOGY

Contractile C2C12 myotube model for studying exercise-inducible responses in skeletal muscle

(2008) Taku Nedachi et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

The chemokine receptors CXCR1/CXCR2 modulate antigen-induced arthritis by regulating adhesion of neutrophils to the synovial microvasculature

(2008) Fernanda M. Coelho et al.   ARTHRITIS AND RHEUMATISM

CXCR2‐specific chemokines mediate leukotriene B4–dependent recruitment of neutrophils to inflamed joints in mice with antigen‐induced arthritis

(2008) Renata Grespan et al.   ARTHRITIS AND RHEUMATISM

Chemokine Signaling via the CXCR2 Receptor Reinforces Senescence

(2008) Juan C. Acosta et al.   CELL

Mice deficient in the CXCR2 ligand, CXCL1 (KC/GRO-α), exhibit increased susceptibility to dextran sodium sulfate (DSS)-induced colitis

(2008) Terez Shea-Donohue et al.   Innate Immunity

Ticks produce highly selective chemokine binding proteins with antiinflammatory activity

(2008) Maud Déruaz et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Th17–ELR+CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

(2008) Thaddeus Carlson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

The Chemokine CXCL1/Growth Related Oncogene Increases Sodium Currents and Neuronal Excitability in Small Diameter Sensory Neurons

(2008) Jun-Gang Wang et al.   Molecular Pain

Traffic of leukocytes in the central nervous system is associated with chemokine up-regulation in a severe model of herpes simplex encephalitis: An intravital microscopy study

(2008) Márcia Carvalho Vilela et al.   NEUROSCIENCE LETTERS