Induced CNS expression of CXCL1 augments neurologic disease in a murine model of multiple sclerosis via enhanced neutrophil recruitment

The contribution of neutrophils to CNS autoimmunity

(2018) Emily R. Pierson et al.   CLINICAL IMMUNOLOGY

Myeloid cell transmigration across the CNS vasculature triggers IL-1β–driven neuroinflammation during autoimmune encephalomyelitis in mice

(2016) Sébastien A. Lévesque et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Inducible Expression of CXCL1 within the Central Nervous System Amplifies Viral-Induced Demyelination

(2016) Brett S. Marro et al.   JOURNAL OF IMMUNOLOGY

Neurotherapeutic Strategies for Multiple Sclerosis

(2016) Teresa C. Frohman et al.   NEUROLOGIC CLINICS

Sphingosine-1-Phosphate Receptor Antagonism Enhances Proliferation and Migration of Engrafted Neural Progenitor Cells in a Model of Viral-Induced Demyelination

(2015) Caroline A. Blanc et al.   AMERICAN JOURNAL OF PATHOLOGY

Plasticity of neutrophils reveals modulatory capacity

(2015) S.M. Perobelli et al.   BRAZILIAN JOURNAL OF MEDICAL AND BIOLOGICAL RESEARCH

Neutrophil-related factors as biomarkers in EAE and MS

(2015) Julie M. Rumble et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Preferential Recruitment of Neutrophils into the Cerebellum and Brainstem Contributes to the Atypical Experimental Autoimmune Encephalomyelitis Phenotype

(2015) Yudong Liu et al.   JOURNAL OF IMMUNOLOGY

CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

(2015) Fengjiao Wu et al.   Journal of Neuroinflammation

Multiple sclerosis—a quiet revolution

(2015) Richard M. Ransohoff et al.   Nature Reviews Neurology

Role of Neutrophils in Exacerbation of Brain Injury After Focal Cerebral Ischemia in Hyperlipidemic Mice

(2015) Josephine Herz et al.   STROKE

Anti-inflammatory mechanisms of IFN-γ studied in experimental autoimmune encephalomyelitis reveal neutrophils as a potential target in multiple sclerosis

(2015) Nichole M. Miller et al.   Frontiers in Neuroscience

Acthar gel treatment suppresses acute exacerbations in a murine model of relapsing-remitting multiple sclerosis

(2014) Matthew F. Cusick et al.   AUTOIMMUNITY

Site-Specific Chemokine Expression Regulates Central Nervous System Inflammation and Determines Clinical Phenotype in Autoimmune Encephalomyelitis

(2014) Joshua S. Stoolman et al.   JOURNAL OF IMMUNOLOGY

Cytokine-Regulated Neutrophil Recruitment Is Required for Brain but Not Spinal Cord Inflammation during Experimental Autoimmune Encephalomyelitis

(2014) Sarah B. Simmons et al.   JOURNAL OF IMMUNOLOGY

Neutrophils Mediate Blood–Spinal Cord Barrier Disruption in Demyelinating Neuroinflammatory Diseases

(2014) Benoit Aubé et al.   JOURNAL OF IMMUNOLOGY

ELR(+) chemokine signaling in host defense and disease in a viral model of central nervous system disease

(2014) Martin P. Hosking et al.   Frontiers in Cellular Neuroscience

Experimental autoimmune encephalomyelitis is a good model of multiple sclerosis if used wisely

(2014) David Baker et al.   Multiple Sclerosis and Related Disorders

Human Neural Precursor Cells Promote Neurologic Recovery in a Viral Model of Multiple Sclerosis

(2014) Lu Chen et al.   Stem Cell Reports

Resveratrol Exacerbates Both Autoimmune and Viral Models of Multiple Sclerosis

(2013) Fumitaka Sato et al.   AMERICAN JOURNAL OF PATHOLOGY

Neutrophils Amplify Autoimmune Central Nervous System Infiltrates by Maturing Local APCs

(2013) K. Steinbach et al.   JOURNAL OF IMMUNOLOGY

Myelin Repair Is Accelerated by Inactivating CXCR2 on Nonhematopoietic Cells

(2013) L. Liu et al.   JOURNAL OF NEUROSCIENCE

Mast cell activation and neutrophil recruitment promotes early and robust inflammation in the meninges in EAE

(2012) Alison L. Christy et al.   JOURNAL OF AUTOIMMUNITY

Epstein–Barr virus-induced gene 3 negatively regulates neuroinflammation and T cell activation following coronavirus-induced encephalomyelitis

(2012) Emanuele Tirotta et al.   JOURNAL OF NEUROIMMUNOLOGY

CXCL1 can be regulated by IL-6 and promotes granulocyte adhesion to brain capillaries during bacterial toxin exposure and encephalomyelitis

(2012) Monica Roy et al.   Journal of Neuroinflammation

Ex vivo spinal cord slice model of neuromyelitis optica reveals novel immunopathogenic mechanisms

(2011) Hua Zhang et al.   ANNALS OF NEUROLOGY

Neutrophil protease inhibition reduces neuromyelitis optica-immunoglobulin G-induced damage in mouse brain

(2011) Samira Saadoun et al.   ANNALS OF NEUROLOGY

G-CSF-mediated thrombopoietin release triggers neutrophil motility and mobilization from bone marrow via induction of Cxcr2 ligands

(2011) A. Kohler et al.   BLOOD

CXCR2 signaling protects oligodendrocyte progenitor cells from IFN-γ/CXCL10-mediated apoptosis

(2011) Emanuele Tirotta et al.   GLIA

Neutrophils in multiple sclerosis are characterized by a primed phenotype

(2011) Matthias Naegele et al.   JOURNAL OF NEUROIMMUNOLOGY

Neutrophils cascading their way to inflammation

(2011) Christian D. Sadik et al.   TRENDS IN IMMUNOLOGY

Extensive infiltration of neutrophils in the acute phase of experimental autoimmune encephalomyelitis in C57BL/6 mice

(2010) Fenglan Wu et al.   HISTOCHEMISTRY AND CELL BIOLOGY

CXCR2-positive neutrophils are essential for cuprizone-induced demyelination: relevance to multiple sclerosis

(2010) LiPing Liu et al.   NATURE NEUROSCIENCE

CXCR2 Signaling Protects Oligodendrocytes and Restricts Demyelination in a Mouse Model of Viral-Induced Demyelination

(2010) Martin P. Hosking et al.   PLoS One

Th17 cells in autoimmune demyelinating disease

(2010) Benjamin Matthew Segal   Seminars in Immunopathology

Neutrophil kinetics in health and disease

(2010) Charlotte Summers et al.   TRENDS IN IMMUNOLOGY

Circulating Ly-6C+ myeloid precursors migrate to the CNS and play a pathogenic role during autoimmune demyelinating disease

(2009) I. L. King et al.   BLOOD

Inhibition of CXCR2 signaling promotes recovery in models of multiple sclerosis

(2009) A.E. Kerstetter et al.   EXPERIMENTAL NEUROLOGY

Inhibition of NADPH Oxidase is Neuroprotective after Ischemia—Reperfusion

(2009) Hai Chen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

A Protective Role for ELR+ Chemokines during Acute Viral Encephalomyelitis

(2009) Martin P. Hosking et al.   PLoS Pathogens

Neuroprotection and Remyelination after Autoimmune Demyelination in Mice that Inducibly Overexpress CXCL1

(2008) Kakuri M. Omari et al.   AMERICAN JOURNAL OF PATHOLOGY

The Th17–ELR+CXC chemokine pathway is essential for the development of central nervous system autoimmune disease

(2008) Thaddeus Carlson et al.   JOURNAL OF EXPERIMENTAL MEDICINE

IL-12– and IL-23–modulated T cells induce distinct types of EAE based on histology, CNS chemokine profile, and response to cytokine inhibition

(2008) Mark A. Kroenke et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET