Endothelial Cdk5 deficit leads to the development of spontaneous epilepsy through CXCL1/CXCR2-mediated reactive astrogliosis

Endothelium-Derived Semaphorin 3G Regulates Hippocampal Synaptic Structure and Plasticity via Neuropilin-2/PlexinA4

(2019) Chao Tan et al.   NEURON

RNA sequencing and swarm intelligence–enhanced classification algorithm development for blood-based disease diagnostics using spliced blood platelet RNA

(2019) Myron G. Best et al.   Nature Protocols

Epilepsy in adults

(2019) Roland D Thijs et al.   LANCET

The Lateral Habenula Directs Coping Styles Under Conditions of Stress Via Recruitment of the Endocannabinoid System

(2018) Anthony L. Berger et al.   BIOLOGICAL PSYCHIATRY

The novel brassinosteroid analog BR4848 inhibits angiogenesis in human endothelial cells and induces apoptosis in human cancer cells in vitro

(2018) Lucie Rárová et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Anti-nociceptive Role of CXCL1 in a Murine Model of Peripheral Nerve Injury-induced Neuropathic Pain

(2018) Ling Cao et al.   NEUROSCIENCE

Feasibility Evaluation of Myocardial Cannabinoid Type 1 Receptor Imaging in Obesity

(2018) Ines Valenta et al.   JACC-Cardiovascular Imaging

Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation

(2018) Mana Taki et al.   Nature Communications

Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration

(2018) Evgenia Lampropoulou et al.   Scientific Reports

Chemogenetic silencing of hippocampal neurons suppresses epileptic neural circuits

(2018) Qi-Gang Zhou et al.   JOURNAL OF CLINICAL INVESTIGATION

Melatonin ameliorates hypoglycemic stress-induced brain endothelial tight junction injury by inhibiting protein nitration of TP53-induced glycolysis and apoptosis regulator

(2017) Cheng-kun Wang et al.   JOURNAL OF PINEAL RESEARCH

Cables1 Inhibits Proliferation and Induces Senescence by Angiotensin II via a p21-Dependent Pathway in Human Umbilical Vein Endothelial Cells

(2017) Zhongyue Pu et al.   JOURNAL OF VASCULAR RESEARCH

Cardiovascular effects of marijuana and synthetic cannabinoids: the good, the bad, and the ugly

(2017) Pal Pacher et al.   Nature Reviews Cardiology

Neuronal hyperexcitability in a mouse model ofSCN8Aepileptic encephalopathy

(2017) Luis F. Lopez-Santiago et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Methodological issues associated with clinical trials in epilepsy

(2017) Edoardo Ferlazzo et al.   Expert Review of Clinical Pharmacology

Chemokine receptor CXCR2 in dorsal root ganglion contributes to the maintenance of inflammatory pain

(2016) De-Li Cao et al.   BRAIN RESEARCH BULLETIN

A brain microvasculature endothelial cell‐specific viral vector with the potential to treat neurovascular and neurological diseases

(2016) Jakob Körbelin et al.   EMBO Molecular Medicine

Microglia-Neuron Communication in Epilepsy

(2016) Ukpong B. Eyo et al.   GLIA

Postnatal activation of TLR4 in astrocytes promotes excitatory synaptogenesis in hippocampal neurons

(2016) Yi Shen et al.   JOURNAL OF CELL BIOLOGY

Glutamate Clearance Is Locally Modulated by Presynaptic Neuronal Activity in the Cerebral Cortex

(2016) Moritz Armbruster et al.   JOURNAL OF NEUROSCIENCE

Pericytes as Inducers of Rapid, Matrix Metalloproteinase-9-Dependent Capillary Damage during Ischemia

(2016) Robert G. Underly et al.   JOURNAL OF NEUROSCIENCE

Selective Deletion of Astroglial FMRP Dysregulates Glutamate Transporter GLT1 and Contributes to Fragile X Syndrome Phenotypes In Vivo

(2016) H. Higashimori et al.   JOURNAL OF NEUROSCIENCE

Mapping synaptic glutamate transporter dysfunction in vivo to regions surrounding Aβ plaques by iGluSnFR two-photon imaging

(2016) J. K. Hefendehl et al.   Nature Communications

Rapid endothelial cytoskeletal reorganization enables early blood–brain barrier disruption and long-term ischaemic reperfusion brain injury

(2016) Yejie Shi et al.   Nature Communications

Inhibition of endothelial Cdk5 reduces tumor growth by promoting non-productive angiogenesis

(2016) Henriette Merk et al.   Oncotarget

Cyclin-dependent kinase 5 stabilizes hypoxia-inducible factor-1α: a novel approach for inhibiting angiogenesis in hepatocellular carcinoma

(2016) Julia Herzog et al.   Oncotarget

Resident microglia rather than peripheral macrophages promote vascularization in brain tumors and are source of alternative pro-angiogenic factors

(2015) Susan Brandenburg et al.   ACTA NEUROPATHOLOGICA

P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy

(2015) Huan Wang et al.   CELL RESEARCH

Endothelial β-Catenin Signaling Is Required for Maintaining Adult Blood–Brain Barrier Integrity and Central Nervous System HomeostasisCLINICAL PERSPECTIVE

(2015) Khiem A. Tran et al.   CIRCULATION

Astrocytic glutamate uptake is slow and does not limit neuronal NMDA receptor activation in the neonatal neocortex

(2015) Elizabeth Hanson et al.   GLIA

Restored glial glutamate transporter EAAT2 function as a potential therapeutic approach for Alzheimer’s disease

(2015) Kou Takahashi et al.   JOURNAL OF EXPERIMENTAL MEDICINE

CXCR2 is essential for cerebral endothelial activation and leukocyte recruitment during neuroinflammation

(2015) Fengjiao Wu et al.   Journal of Neuroinflammation

Epilepsy: new advances

(2015) Solomon L Moshé et al.   LANCET

Formation and maintenance of the BBB

(2015) Marie Blanchette et al.   MECHANISMS OF DEVELOPMENT

Microcircuits and their interactions in epilepsy: is the focus out of focus?

(2015) Jeanne T Paz et al.   NATURE NEUROSCIENCE

Laser-scanning astrocyte mapping reveals increased glutamate-responsive domain size and disrupted maturation of glutamate uptake following neonatal cortical freeze-lesion

(2014) Moritz Armbruster et al.   Frontiers in Cellular Neuroscience

Chronic stress-induced disruption of the astrocyte network is driven by structural atrophy and not loss of astrocytes

(2013) Ross J. Tynan et al.   ACTA NEUROPATHOLOGICA

Targeted therapy of brain ischaemia using Fas ligand antibody conjugated PEG-lipid nanoparticles

(2013) Ying-mei Lu et al.   BIOMATERIALS

Expression of CXCL1 in human endothelial cells induces angiogenesis through the CXCR2 receptor and the ERK1/2 and EGF pathways

(2013) Makito Miyake et al.   LABORATORY INVESTIGATION

Development, maintenance and disruption of the blood-brain barrier

(2013) Birgit Obermeier et al.   NATURE MEDICINE

Isolation and expansion of human and mouse brain microvascular endothelial cells

(2013) Stefania E Navone et al.   Nature Protocols

Cyclin-Dependent Kinase 5–Mediated Hyperphosphorylation of Sirtuin-1 Contributes to the Development of Endothelial Senescence and Atherosclerosis

(2012) Bo Bai et al.   CIRCULATION

Blockade of Astrocytic Glutamate Uptake in the Prefrontal Cortex Induces Anhedonia

(2012) Catherine S John et al.   NEUROPSYCHOPHARMACOLOGY

Roscovitine blocks leukocyte extravasation by inhibition of cyclin-dependent kinases 5 and 9

(2011) Nina Berberich et al.   BRITISH JOURNAL OF PHARMACOLOGY

Neuregulin 1 regulates excitability of fast-spiking neurons through Kv1.1 and acts in epilepsy

(2011) Ke-Xin Li et al.   NATURE NEUROSCIENCE

Cyclin-dependent Kinase 5 Regulates Endothelial Cell Migration and Angiogenesis

(2010) Johanna Liebl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alterations in protein expression and membrane properties during Müller cell gliosis in a murine model of transient retinal ischemia

(2010) Petra G. Hirrlinger et al.   NEUROSCIENCE LETTERS