Neutralization of the IL-17 axis diminishes neutrophil invasion and protects from ischemic stroke

IL-17A Inhibits the Expansion of IL-17A-Producing T Cells in Mice through "Short-Loop" Inhibition via IL-17 Receptor

(2014) E. Smith et al.   JOURNAL OF IMMUNOLOGY

Tissue-Type Plasminogen Activator Is a Regulator of Monocyte Diapedesis through the Brain Endothelial Barrier

(2014) A. Reijerkerk et al.   JOURNAL OF IMMUNOLOGY

Chemokine receptor CXCR2: Physiology regulator and neuroinflammation controller?

(2012) Mike Veenstra et al.   JOURNAL OF NEUROIMMUNOLOGY

Natural Killer T Cell–derived IL-17 Mediates Lung Ischemia–Reperfusion Injury

(2011) Ashish K. Sharma et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Inhibition of lymphocyte trafficking shields the brain against deleterious neuroinflammation after stroke

(2011) Arthur Liesz et al.   BRAIN

Timeliness of Tissue-Type Plasminogen Activator Therapy in Acute Ischemic Stroke

(2011) Gregg C. Fonarow et al.   CIRCULATION

Interleukin-17C Promotes Th17 Cell Responses and Autoimmune Disease via Interleukin-17 Receptor E

(2011) Seon Hee Chang et al.   IMMUNITY

Functional Specialization of Interleukin-17 Family Members

(2011) Yoichiro Iwakura et al.   IMMUNITY

Microglial Cells Contribute to Endogenous Brain Defenses after Acute Neonatal Focal Stroke

(2011) J. V. Faustino et al.   JOURNAL OF NEUROSCIENCE

Regulatory B Cells Limit CNS Inflammation and Neurologic Deficits in Murine Experimental Stroke

(2011) X. Ren et al.   JOURNAL OF NEUROSCIENCE

Stroke and the immune system: from pathophysiology to new therapeutic strategies

(2011) Richard Macrez et al.   LANCET NEUROLOGY

The immunology of stroke: from mechanisms to translation

(2011) Costantino Iadecola et al.   NATURE MEDICINE

Increased Brain Injury and Worsened Neurological Outcome in Interleukin-4 Knockout Mice After Transient Focal Cerebral Ischemia

(2011) Xiaoxing Xiong et al.   STROKE

The Sterile Inflammatory Response

(2010) Kenneth L. Rock et al.   Annual Review of Immunology

LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study

(2010) M. C. Genovese et al.   ARTHRITIS AND RHEUMATISM

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

(2010) C. Kleinschnitz et al.   BLOOD

Neutrophil elastase inhibitor prevents ischemic brain damage via reduction of vasogenic edema

(2010) Yuka Ikegame et al.   HYPERTENSION RESEARCH

Effects of AIN457, a Fully Human Antibody to Interleukin-17A, on Psoriasis, Rheumatoid Arthritis, and Uveitis

(2010) W. Hueber et al.   Science Translational Medicine

Tissue-type plasminogen activator (t-PA) induces stromelysin-1 (MMP-3) in endothelial cells through activation of lipoprotein receptor-related protein

(2009) Y. Suzuki et al.   BLOOD

Activation of cannabinoid 2 receptors protects against cerebral ischemia by inhibiting neutrophil recruitment

(2009) Sasidhar Murikinati et al.   FASEB JOURNAL

Interleukin-17-Producing γδ T Cells Selectively Expand in Response to Pathogen Products and Environmental Signals

(2009) Bruno Martin et al.   IMMUNITY

Interleukin-1 and IL-23 Induce Innate IL-17 Production from γδ T Cells, Amplifying Th17 Responses and Autoimmunity

(2009) Caroline E. Sutton et al.   IMMUNITY

IL-17 produced by neutrophils regulates IFN-γ–mediated neutrophil migration in mouse kidney ischemia-reperfusion injury

(2009) Li Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Microglia Protect Neurons against Ischemia by Synthesis of Tumor Necrosis Factor

(2009) K. L. Lambertsen et al.   JOURNAL OF NEUROSCIENCE

Pivotal role of cerebral interleukin-17–producing γδT cells in the delayed phase of ischemic brain injury

(2009) Takashi Shichita et al.   NATURE MEDICINE

Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke

(2009) Arthur Liesz et al.   NATURE MEDICINE

Temporal and Spatial Dynamics of Cerebral Immune Cell Accumulation in Stroke

(2009) Mathias Gelderblom et al.   STROKE