Inflammatory Cascade in Alzheimer’s Disease Pathogenesis: A Review of Experimental Findings

Nanotechnology as a therapeutic strategy to prevent neuropsychomotor alterations associated with hypercholesterolemia

(2021) Matheus Scarpatto Rodrigues et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Evaluation of Aducanumab for Alzheimer Disease

(2021) G. Caleb Alexander et al.   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Microglial Function and Regulation during Development, Homeostasis and Alzheimer’s Disease

(2021) Brad T. Casali et al.   Cells

Overexpressing low-density lipoprotein receptor reduces tau-associated neurodegeneration in relation to apoE-linked mechanisms

(2021) Yang Shi et al.   NEURON

Relationship Between Amyloid-β Deposition and Blood–Brain Barrier Dysfunction in Alzheimer’s Disease

(2021) Dong Wang et al.   Frontiers in Cellular Neuroscience

The microglial lysosomal system in Alzheimer’s disease: Guardian against proteinopathy

(2021) Zoë P. Van Acker et al.   AGEING RESEARCH REVIEWS

GSK3β is involved in promoting Alzheimer’s disease pathologies following chronic systemic exposure to Porphyromonas gingivalis lipopolysaccharide in amyloid precursor proteinNL-F/NL-F knock-in mice

(2021) Muzhou Jiang et al.   BRAIN BEHAVIOR AND IMMUNITY

The neuroinvasive potential of SARS‐CoV2 may be at least partially responsible for the respiratory failure of COVID‐19 patients

(2020) Yan‐Chao Li et al.   JOURNAL OF MEDICAL VIROLOGY

Clinical and Bacterial Markers of Periodontitis and Their Association with Incident All-Cause and Alzheimer’s Disease Dementia in a Large National Survey

(2020) May A. Beydoun et al.   JOURNAL OF ALZHEIMERS DISEASE

IL-1β, IL-6, IL-10, and TNFα Single Nucleotide Polymorphisms in Human Influence the Susceptibility to Alzheimer’s Disease Pathology

(2020) Mirjana Babić Leko et al.   JOURNAL OF ALZHEIMERS DISEASE

Role of dietary fatty acids in microglial polarization in Alzheimer’s disease

(2020) Smita Eknath Desale et al.   Journal of Neuroinflammation

Randomized placebo-controlled trial of the effects of aspirin on dementia and cognitive decline

(2020) Joanne Ryan et al.   NEUROLOGY

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

(2020) Ling Mao et al.   JAMA Neurology

A Path Toward Precision Medicine for Neuroinflammatory Mechanisms in Alzheimer's Disease

(2020) Harald Hampel et al.   Frontiers in Immunology

The Physiology, Pathology, and Potential Therapeutic Applications of the TREM2 Signaling Pathway

(2020) Aleksandra Deczkowska et al.   CELL

Blood-brain barrier integrity in the pathogenesis of Alzheimer’s disease

(2020) Zhangsen Huang et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Neurobiology of COVID-19

(2020) Majid Fotuhi et al.   JOURNAL OF ALZHEIMERS DISEASE

Neurological associations of COVID-19

(2020) Mark A Ellul et al.   LANCET NEUROLOGY

Lipoic Acid and Fish Oil Combination Potentiates Neuroinflammation and Oxidative Stress Regulation and Prevents Cognitive Decline of Rats After Sepsis

(2020) Amanda Della Giustina et al.   MOLECULAR NEUROBIOLOGY

Invite Review – Understanding cause and effect in Alzheimer's pathophysiology: Implications for clinical trials

(2020) D. Boche et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) and the Central Nervous System

(2020) Fernanda G. De Felice et al.   TRENDS IN NEUROSCIENCES

Immediate and long-term consequences of COVID-19 infections for the development of neurological disease

(2020) Michael T. Heneka et al.   Alzheimers Research & Therapy

Functional insights from biophysical study of TREM2 interactions with apoE and Aβ 1‐42

(2020) Daniel L. Kober et al.   Alzheimers & Dementia

High Cholesterol Diet Exacerbates Blood-Brain Barrier Disruption in LDLr–/– Mice: Impact on Cognitive Function

(2020) Jade de Oliveira et al.   JOURNAL OF ALZHEIMERS DISEASE

Apolipoprotein E: Structural Insights and Links to Alzheimer Disease Pathogenesis

(2020) Yun Chen et al.   NEURON

Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors

(2019) Stephen S. Dominy et al.   Science Advances

Impact of Gold Nanoparticles on Amyloid β-Induced Alzheimer’s Disease in a Rat Animal Model: Involvement of STIM Proteins

(2019) Mehdi Sanati et al.   ACS Chemical Neuroscience

Natural Compounds for Alzheimer’s Disease Therapy: A Systematic Review of Preclinical and Clinical Studies

(2019) Stephanie Andrade et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Natural Products in Alzheimer’s Disease Therapy: Would Old Therapeutic Approaches Fix the Broken Promise of Modern Medicines?

(2019) Habtemariam   MOLECULES

INTREPAD

(2019) Pierre-François Meyer et al.   NEUROLOGY

Infection-Induced Systemic Inflammation Is a Potential Driver of Alzheimer's Disease Progression

(2019) Vijayasree V. Giridharan et al.   Frontiers in Aging Neuroscience

Impaired Peripheral Lymphatic Function and Cerebrospinal Fluid Outflow in a Mouse Model of Alzheimer’s Disease

(2019) Sunkuk Kwon et al.   JOURNAL OF ALZHEIMERS DISEASE

Modifiable Risk Factors for Alzheimer’s Disease

(2019) George A. Edwards III et al.   Frontiers in Aging Neuroscience

Neuroinflammation in Alzheimer’s Disease: Microglia, Molecular Participants and Therapeutic Choices

(2019) Haijun Wang et al.   Current Alzheimer Research

Amyloid-beta impairs insulin signaling by accelerating autophagy-lysosomal degradation of LRP-1 and IR-β in blood-brain barrier endothelial cells in vitro and in 3XTg-AD mice

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Amyloid-β-independent regulators of tau pathology in Alzheimer disease

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Minocycline at 2 Different Dosages vs Placebo for Patients With Mild Alzheimer Disease

(2019) Robert Howard et al.   JAMA Neurology

Disease-Associated Microglia: A Universal Immune Sensor of Neurodegeneration

(2018) Aleksandra Deczkowska et al.   CELL

Inhibition of protein misfolding and aggregation by natural phenolic compounds

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Microglia and Aging: The Role of the TREM2–DAP12 and CX3CL1-CX3CR1 Axes

(2018) Carmen Mecca et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Alzheimer’s Disease Can Be Spared by Nonsteroidal Anti-Inflammatory Drugs

(2018) Patrick L. McGeer et al.   JOURNAL OF ALZHEIMERS DISEASE

The Gut Microbiome Alterations and Inflammation-Driven Pathogenesis of Alzheimer’s Disease—a Critical Review

(2018) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Could Alzheimer’s Disease Originate in the Periphery and If So How So?

(2018) Gerwyn Morris et al.   MOLECULAR NEUROBIOLOGY

Amyloid-beta modulates microglial responses by binding to the triggering receptor expressed on myeloid cells 2 (TREM2)

(2018) Li Zhong et al.   Molecular Neurodegeneration

Microglial control of astrocytes in response to microbial metabolites

(2018) Veit Rothhammer et al.   NATURE

Elevated TREM2 Gene Dosage Reprograms Microglia Responsivity and Ameliorates Pathological Phenotypes in Alzheimer’s Disease Models

(2018) C.Y. Daniel Lee et al.   NEURON

Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease

(2018) Fuyuki Kametani et al.   Frontiers in Neuroscience

Tau and neuroinflammation: What impact for Alzheimer's Disease and Tauopathies?

(2018) Cyril Laurent et al.   Biomedical Journal

Vitamin D3-Enriched Diet Correlates with a Decrease of Amyloid Plaques in the Brain of AβPP Transgenic Mice

(2018) Jin Yu et al.   JOURNAL OF ALZHEIMERS DISEASE

Omega-3 Fatty Acids Enhance Phagocytosis of Alzheimer's Disease-Related Amyloid-β42 by Human Microglia and Decrease Inflammatory Markers

(2018) Erik Hjorth et al.   JOURNAL OF ALZHEIMERS DISEASE

Increased Susceptibility to Amyloid-β-Induced Neurotoxicity in Mice Lacking the Low-Density Lipoprotein Receptor

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The Involvement of NLRP3 on the Effects of Minocycline in an AD-Like Pathology Induced by β-Amyloid Oligomers Administered to Mice

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Inflammasome signalling in brain function and neurodegenerative disease

(2018) Michael T. Heneka et al.   NATURE REVIEWS NEUROSCIENCE

Nilvadipine in mild to moderate Alzheimer disease: A randomised controlled trial

(2018) Brian Lawlor et al.   PLOS MEDICINE

Common Infections May Lead to Alzheimer’s Disease

(2018) Yuyan Wang et al.   VIROLOGICA SINICA

New insights into the role of TREM2 in Alzheimer’s disease

(2018) Maud Gratuze et al.   Molecular Neurodegeneration

Microglia in Neurological Diseases: A Road Map to Brain-Disease Dependent-Inflammatory Response

(2018) Sara Bachiller et al.   Frontiers in Cellular Neuroscience

Gut Microbiota and Their Neuroinflammatory Implications in Alzheimer’s Disease

(2018) Vo Giau et al.   Nutrients

Vitamin D and Its Analogues Decrease Amyloid-β (Aβ) Formation and Increase Aβ-Degradation

(2017) Marcus Grimm et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Blood-Brain Barrier Dysfunction and the Pathogenesis of Alzheimer’s Disease

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Receptor for advanced glycation end products mediates sepsis-triggered amyloid-β accumulation, Tau phosphorylation, and cognitive impairment

(2017) Juciano Gasparotto et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TREM2-Ligand Interactions in Health and Disease

(2017) Daniel L. Kober et al.   JOURNAL OF MOLECULAR BIOLOGY

Factors Influencing the Gut Microbiota, Inflammation, and Type 2 Diabetes

(2017) Li Wen et al.   JOURNAL OF NUTRITION

Gold nanoparticles prevent cognitive deficits, oxidative stress and inflammation in a rat model of sporadic dementia of Alzheimer's type

(2017) Alexandre Pastoris Muller et al.   Materials Science & Engineering C-Materials for Biological Applications

Late onset Alzheimer’s disease genetics implicates microglial pathways in disease risk

(2017) Anastasia G. Efthymiou et al.   Molecular Neurodegeneration

Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding

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ApoE4 markedly exacerbates tau-mediated neurodegeneration in a mouse model of tauopathy

(2017) Yang Shi et al.   NATURE

Microglia-derived ASC specks cross-seed amyloid-β in Alzheimer’s disease

(2017) Carmen Venegas et al.   NATURE

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

(2017) Rebecca Sims et al.   NATURE GENETICS

The blood-brain barrier in Alzheimer's disease

(2017) Elena Zenaro et al.   NEUROBIOLOGY OF DISEASE

The sterile controversy on the amyloid cascade hypothesis

(2017) Marco Canevelli et al.   NEUROSCIENCE AND BIOBEHAVIORAL REVIEWS

Minocycline reduces inflammatory parameters in the brain structures and serum and reverses memory impairment caused by the administration of amyloid β (1-42) in mice

(2017) Michelle Lima Garcez et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

NLRP3 Inflammasome in Neurological Diseases, from Functions to Therapies

(2017) Limin Song et al.   Frontiers in Cellular Neuroscience

Dementia-related agitation: a review of non-pharmacological interventions and analysis of risks and benefits of pharmacotherapy

(2017) E O Ijaopo   Translational Psychiatry

Wnt/TLR Dialog in Neuroinflammation, Relevance in Alzheimer’s Disease

(2017) Juan M. Zolezzi et al.   Frontiers in Immunology

Human Truncated Tau is Using a Different Mechanism from Amyloid-β to Damage the Blood-Brain Barrier

(2017) Andrej Kovac et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuroinflammation in Alzheimer's Disease: Mechanisms, Pathologic Consequences, and Potential for Therapeutic Manipulation

(2017) Kenneth Hensley   JOURNAL OF ALZHEIMERS DISEASE

Alzheimer's Disease and the Amyloid-β Peptide

(2017) M. Paul Murphy et al.   JOURNAL OF ALZHEIMERS DISEASE

Plaque-Associated Local Toxicity Increases over the Clinical Course of Alzheimer Disease

(2016) Alberto Serrano-Pozo et al.   AMERICAN JOURNAL OF PATHOLOGY

Microglia show altered morphology and reduced arborization in human brain during aging and Alzheimer's disease

(2016) Danielle S. Davies et al.   BRAIN PATHOLOGY

Effects of CX3CR1 and Fractalkine Chemokines in Amyloid Beta Clearance and p-Tau Accumulation in Alzheimer,s Disease (AD) Rodent Models: Is Fractalkine a Systemic Biomarker for AD?

(2016) José Joaquín Merino et al.   Current Alzheimer Research

The amyloid hypothesis of Alzheimer's disease at 25 years

(2016) Dennis J Selkoe et al.   EMBO Molecular Medicine

Secret talk between adipose tissue and central nervous system via secreted factors—an emerging frontier in the neurodegenerative research

(2016) Avinash Parimisetty et al.   Journal of Neuroinflammation

Large Soluble Oligomers of Amyloid β-Protein from Alzheimer Brain Are Far Less Neuroactive Than the Smaller Oligomers to Which They Dissociate

(2016) Ting Yang et al.   JOURNAL OF NEUROSCIENCE

Opposing roles of the triggering receptor expressed on myeloid cells 2 and triggering receptor expressed on myeloid cells-like transcript 2 in microglia activation

(2016) Honghua Zheng et al.   NEUROBIOLOGY OF AGING

Assessment of the genetic variance of late-onset Alzheimer's disease

(2016) Perry G. Ridge et al.   NEUROBIOLOGY OF AGING

TREM2 Haplodeficiency in Mice and Humans Impairs the Microglia Barrier Function Leading to Decreased Amyloid Compaction and Severe Axonal Dystrophy

(2016) Peng Yuan et al.   NEURON

Blood-Brain Barrier Leakage in Patients with Early Alzheimer Disease

(2016) Harm J. van de Haar et al.   RADIOLOGY

Fenamate NSAIDs inhibit the NLRP3 inflammasome and protect against Alzheimer’s disease in rodent models

(2016) Michael J. D. Daniels et al.   Nature Communications

The triggering receptor expressed on myeloid cells 2 (TREM2) is associated with enhanced inflammation, neuropathological lesions and increased risk for Alzheimer's dementia

(2015) Panos Roussos et al.   Alzheimers & Dementia

Involvement of inflammation in Alzheimer’s disease pathogenesis and therapeutic potential of anti-inflammatory agents

(2015) Sina Shadfar et al.   ARCHIVES OF PHARMACAL RESEARCH

Establishment and Dysfunction of the Blood-Brain Barrier

(2015) Zhen Zhao et al.   CELL

The interleukin 1 alpha, interleukin 1 beta, interleukin 6 and alpha-2-macroglobulin serum levels in patients with early or late onset Alzheimer's disease, mild cognitive impairment or Parkinson's disease

(2015) Erdinç Dursun et al.   JOURNAL OF NEUROIMMUNOLOGY

Resveratrol decreases the insoluble Aβ1–42 level in hippocampus and protects the integrity of the blood–brain barrier in AD rats

(2015) H.F. Zhao et al.   NEUROSCIENCE

Neuroinflammation in Alzheimer’s disease; A source of heterogeneity and target for personalized therapy

(2015) C.H. Latta et al.   NEUROSCIENCE

Revisiting the Mechanisms of CNS Immune Privilege

(2015) Antoine Louveau et al.   TRENDS IN IMMUNOLOGY

The Blood–Brain Barrier

(2015) Richard Daneman et al.   Cold Spring Harbor Perspectives in Biology

Does Infection-Induced Immune Activation Contribute to Dementia?

(2015) Tatiana Barichello et al.   Aging and Disease

Metabolic Risk Factors of Sporadic Alzheimer's Disease: Implications in the Pathology, Pathogenesis and Treatment

(2015) Sasanka Chakrabarti et al.   Aging and Disease

β-Amyloid: the key peptide in the pathogenesis of Alzheimer’s disease

(2015) Xiaojuan Sun et al.   Frontiers in Pharmacology

Inflammation, defective insulin signaling, and neuronal dysfunction in Alzheimer's disease

(2014) Sergio T. Ferreira et al.   Alzheimers & Dementia

Role of the Microbiota in Immunity and Inflammation

(2014) Yasmine Belkaid et al.   CELL

Pattern recognition receptors and central nervous system repair

(2014) Kristina A. Kigerl et al.   EXPERIMENTAL NEUROLOGY

NLRP3 Deficiency Ameliorates Neurovascular Damage in Experimental Ischemic Stroke

(2014) Fan Yang et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Long-Term Systemic Inflammation and Cognitive Impairment in a Population-Based Cohort

(2014) Margarete A. Wichmann et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Body Fluid Cytokine Levels in Mild Cognitive Impairment and Alzheimer’s Disease: a Comparative Overview

(2014) Frederic Brosseron et al.   MOLECULAR NEUROBIOLOGY

Septic encephalopathy: does inflammation drive the brain crazy?

(2014) Felipe Dal-Pizzol et al.   REVISTA BRASILEIRA DE PSIQUIATRIA

Microglia change from a reactive to an age-like phenotype with the time in culture

(2014) Cláudia Caldeira et al.   Frontiers in Cellular Neuroscience

Systemic inflammation, blood-brain barrier vulnerability and cognitive/non-cognitive symptoms in Alzheimer disease: relevance to pathogenesis and therapy

(2014) Shuko Takeda et al.   Frontiers in Aging Neuroscience

The amyloid cascade-inflammatory hypothesis of Alzheimer disease: implications for therapy

(2013) Patrick L. McGeer et al.   ACTA NEUROPATHOLOGICA

Aspirin-Triggered Lipoxin A4 Stimulates Alternative Activation of Microglia and Reduces Alzheimer Disease–Like Pathology in Mice

(2013) Rodrigo Medeiros et al.   AMERICAN JOURNAL OF PATHOLOGY

AIM2 and NLRP3 inflammasomes activate both apoptotic and pyroptotic death pathways via ASC

(2013) V Sagulenko et al.   CELL DEATH AND DIFFERENTIATION

Inflammation in neurodegenerative diseases - an update

(2013) Sandra Amor et al.   IMMUNOLOGY

Melatonin in Alzheimer’s Disease

(2013) Li Lin et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Sequential Proteolytic Processing of the Triggering Receptor Expressed on Myeloid Cells-2 (TREM2) Protein by Ectodomain Shedding and γ-Secretase-dependent Intramembranous Cleavage

(2013) Patrick Wunderlich et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Blood–Brain Barrier Dysfunction as a Cause and Consequence of Alzheimer's Disease

(2013) Michelle A Erickson et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Systemic immune system alterations in early stages of Alzheimer's disease

(2013) Rongzhen Zhang et al.   JOURNAL OF NEUROIMMUNOLOGY

Differential Relationships of Reactive Astrocytes and Microglia to Fibrillar Amyloid Deposits in Alzheimer Disease

(2013) Alberto Serrano-Pozo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Tracking pathophysiological processes in Alzheimer's disease: an updated hypothetical model of dynamic biomarkers

(2013) Clifford R Jack et al.   LANCET NEUROLOGY

The NLRP3 Inflammasome in Alzheimer’s Disease

(2013) Meng-Shan Tan et al.   MOLECULAR NEUROBIOLOGY

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease

(2013) Jean-Charles Lambert et al.   NATURE GENETICS

Pleiotropic Actions of Insulin Resistance and Inflammation in Metabolic Homeostasis

(2013) J. I. Odegaard et al.   SCIENCE

Oligomeric amyloid β induces IL-1β processing via production of ROS: implication in Alzheimer’s disease

(2013) B Parajuli et al.   Cell Death & Disease

ω-3 Fatty Acids in the Prevention of Cognitive Decline in Humans

(2013) Tommy Cederholm et al.   Advances in Nutrition

Inflammation in Alzheimer Disease--A Brief Review of the Basic Science and Clinical Literature

(2013) T. Wyss-Coray et al.   Cold Spring Harbor Perspectives in Medicine

Neuropathological Alterations in Alzheimer Disease

(2013) A. Serrano-Pozo et al.   Cold Spring Harbor Perspectives in Medicine

The Genetics of Alzheimer Disease

(2013) R. E. Tanzi   Cold Spring Harbor Perspectives in Medicine

The Clinical Problem of Symptomatic Alzheimer Disease and Mild Cognitive Impairment

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National Institute on Aging–Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

(2012) Bradley T. Hyman et al.   Alzheimers & Dementia

Mechanisms of Amyloid-β Peptide Clearance: Potential Therapeutic Targets for Alzheimer's Disease

(2012) Sang-Sun Yoon et al.   Biomolecules & Therapeutics

Alzheimer brain-derived amyloid β-protein impairs synaptic remodeling and memory consolidation

(2012) Gilyana G. Borlikova et al.   NEUROBIOLOGY OF AGING

Innate Immunity and the Etiology of Late-Onset Alzheimer’s Disease

(2012) Piet Eikelenboom et al.   Neurodegenerative Diseases

TREM2 Variants in Alzheimer's Disease

(2012) Rita Guerreiro et al.   NEW ENGLAND JOURNAL OF MEDICINE

CCL2 Is Associated with a Faster Rate of Cognitive Decline during Early Stages of Alzheimer's Disease

(2012) Karin Westin et al.   PLoS One

Leukocyte CCR2 Expression Is Associated with Mini-Mental State Examination Score in Older Adults

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Extended results of the Alzheimer’s disease anti-inflammatory prevention trial

(2011) John C. Breitner et al.   Alzheimers & Dementia

The diagnosis of dementia due to Alzheimer’s disease: Recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer's disease

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Amyloid Precursor Protein Processing and Alzheimer's Disease

(2011) Richard J. O'Brien et al.   Annual Review of Neuroscience

TLR2 Is a Primary Receptor for Alzheimer's Amyloid   Peptide To Trigger Neuroinflammatory Activation

(2011) S. Liu et al.   JOURNAL OF IMMUNOLOGY

Blocking IL-1 Signaling Rescues Cognition, Attenuates Tau Pathology, and Restores Neuronal  -Catenin Pathway Function in an Alzheimer's Disease Model

(2011) M. Kitazawa et al.   JOURNAL OF IMMUNOLOGY

Proteolytic processing of Alzheimer’s β-amyloid precursor protein

(2011) Han Zhang et al.   JOURNAL OF NEUROCHEMISTRY

Alzheimer's Disease Brain-Derived Amyloid- -Mediated Inhibition of LTP In Vivo Is Prevented by Immunotargeting Cellular Prion Protein

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Compounding artefacts with uncertainty, and an amyloid cascade hypothesis that is ‘too big to fail’

(2011) Rudy J Castellani et al.   JOURNAL OF PATHOLOGY

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

(2011) Eric Karran et al.   NATURE REVIEWS DRUG DISCOVERY

Septic encephalopathy: Inflammation in man and mouse

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Aβ Accelerates the Spatiotemporal Progression of Tau Pathology and Augments Tau Amyloidosis in an Alzheimer Mouse Model

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A Meta-Analysis of Cytokines in Alzheimer's Disease

(2010) Walter Swardfager et al.   BIOLOGICAL PSYCHIATRY

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Role of Vascular Risk Factors and Vascular Dysfunction in Alzheimer's Disease

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Staging anti-inflammatory therapy in Alzheimer’s disease

(2010) Mathieu P. Lichtenstein   Frontiers in Aging Neuroscience

Atherosclerotic mice exhibit systemic inflammation in periadventitial and visceral adipose tissue, liver, and pancreatic islets

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Clearance of Amyloid-β Peptide Across the Blood-Brain Barrier: Implication for Therapies in Alzheimers Disease

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Meta-analysis of linkage studies for Alzheimer's disease—A web resource

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The blood-brain barrier in brain homeostasis and neurological diseases

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High cholesterol-induced neuroinflammation and amyloid precursor protein processing correlate with loss of working memory in mice

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Inflammatory Response in the Hippocampus of PS1M146L/APP751SL Mouse Model of Alzheimer's Disease: Age-Dependent Switch in the Microglial Phenotype from Alternative to Classic

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Regulation of β-amyloid levels in the brain of cholesterol-fed rabbit, a model system for sporadic Alzheimer’s disease

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The NALP3 inflammasome is involved in the innate immune response to amyloid-β

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The Blood-Brain Barrier in Health and Chronic Neurodegenerative Disorders

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Screening of innate immune receptors in neurodegenerative diseases: A similar pattern

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