Molecular interaction between type 2 diabetes and Alzheimer’s disease through cross-seeding of protein misfolding

Risk of Incident Alzheimer's Disease in Diabetic Patients: A Systematic Review of Prospective Trials

(2017) Daniel Kopf et al.   JOURNAL OF ALZHEIMERS DISEASE

Neuropathologically mixed Alzheimer’s and Lewy body disease: burden of pathological protein aggregates differs between clinical phenotypes

(2015) Lauren Walker et al.   ACTA NEUROPATHOLOGICA

In Vivo Seeding and Cross-Seeding of Localized Amyloidosis

(2015) Marie E. Oskarsson et al.   AMERICAN JOURNAL OF PATHOLOGY

Diabetes Mellitus Accelerates Aβ Pathology in Brain Accompanied by Enhanced GAβ Generation in Nonhuman Primates

(2015) Sachi Okabayashi et al.   PLoS One

Exogenous amyloidogenic proteins function as seeds in amyloid β-protein aggregation

(2014) Kenjiro Ono et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Neuroinflammation and neurologic deficits in diabetes linked to brain accumulation of amylin

(2014) Sarah Srodulski et al.   Molecular Neurodegeneration

Amyloid-β oligomers as a template for secondary amyloidosis in Alzheimer's disease

(2014) Marcos J. Guerrero-Muñoz et al.   NEUROBIOLOGY OF DISEASE

Association between Amylin and Amyloid-β Peptides in Plasma in the Context of Apolipoprotein E4 Allele

(2014) Wei Qiao Qiu et al.   PLoS One

Amylin deposition in the brain: A second amyloid in Alzheimer disease?

(2013) Kaleena Jackson et al.   ANNALS OF NEUROLOGY

Impaired glycemia increases disease progression in mild cognitive impairment

(2013) Jill K. Morris et al.   NEUROBIOLOGY OF AGING

Cross-Seeding of Misfolded Proteins: Implications for Etiology and Pathogenesis of Protein Misfolding Diseases

(2013) Rodrigo Morales et al.   PLoS Pathogens

Microcin Amyloid Fibrils A Are Reservoir of Toxic Oligomeric Species

(2012) Mohammad Shahnawaz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Brain insulin resistance accelerates Aβ fibrillogenesis by inducing GM1 ganglioside clustering in the presynaptic membranes

(2012) Naoki Yamamoto et al.   JOURNAL OF NEUROCHEMISTRY

The Diabetes Drug Liraglutide Prevents Degenerative Processes in a Mouse Model of Alzheimer's Disease

(2011) P. L. McClean et al.   JOURNAL OF NEUROSCIENCE

Identification of Hot Regions of the Aβ-IAPP Interaction Interface as High-Affinity Binding Sites in both Cross- and Self-Association

(2010) Erika Andreetto et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

Risk of developing dementia in people with diabetes and mild cognitive impairment

(2010) Latha Velayudhan et al.   BRITISH JOURNAL OF PSYCHIATRY

Insulin resistance, diabetes and cognitive function: Consequences for preventative strategies

(2010) I. Bourdel-Marchasson et al.   DIABETES & METABOLISM

Synergistic Interactions between A , Tau, and  -Synuclein: Acceleration of Neuropathology and Cognitive Decline

(2010) L. K. Clinton et al.   JOURNAL OF NEUROSCIENCE

Rosiglitazone Rescues Memory Impairment in Alzheimer's Transgenic Mice: Mechanisms Involving a Reduced Amyloid and Tau Pathology

(2010) Luis Escribano et al.   NEUROPSYCHOPHARMACOLOGY

Intracerebroventricular insulin improves spatial learning and memory in male Wistar rats.

(2009) V. Haj-ali et al.   BEHAVIORAL NEUROSCIENCE

Common features between diabetes mellitus and Alzheimer’s disease

(2009) J. Götz et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Increased Tau Phosphorylation and Cleavage in Mouse Models of Type 1 and Type 2 Diabetes

(2009) Bhumsoo Kim et al.   ENDOCRINOLOGY

Type 1 diabetes exaggerates features of Alzheimer's disease in APP transgenic mice

(2009) Corinne G. Jolivalt et al.   EXPERIMENTAL NEUROLOGY

PIOGLITAZONE IMPROVED COGNITION IN A PILOT STUDY ON PATIENTS WITH ALZHEIMER'S DISEASE AND MILD COGNITIVE IMPAIRMENT WITH DIABETES MELLITUS

(2009) Haruo Hanyu et al.   JOURNAL OF THE AMERICAN GERIATRICS SOCIETY

Experimental Diabetes Mellitus Exacerbates Tau Pathology in a Transgenic Mouse Model of Alzheimer's Disease

(2009) Yazi D. Ke et al.   PLoS One

Mixed Brain Pathologies in Dementia: The BrainNet Europe Consortium Experience

(2008) Gabor G. Kovacs et al.   DEMENTIA AND GERIATRIC COGNITIVE DISORDERS

Beta amyloid and hyperphosphorylated tau deposits in the pancreas in type 2 diabetes

(2008) Judith Miklossy et al.   NEUROBIOLOGY OF AGING