Animal Models Utilized for the Development of Influenza Virus Vaccines

Screening and development of monoclonal antibodies for identification of ferret T follicular helper cells

(2021) Wenbo Jiang et al.   Scientific Reports

Chimeric Hemagglutinin-Based Live-Attenuated Vaccines Confer Durable Protective Immunity against Influenza A Viruses in a Preclinical Ferret Model

(2021) Wen-Chun Liu et al.   Vaccines

Next generation methodology for updating HA vaccines against emerging human seasonal influenza A(H3N2) viruses

(2021) James D. Allen et al.   Scientific Reports

Antibody Focusing to Conserved Sites of Vulnerability: The Immunological Pathways for ‘Universal’ Influenza Vaccines

(2021) Maya Sangesland et al.   Vaccines

Quadrivalent influenza nanoparticle vaccines induce broad protection

(2021) Seyhan Boyoglu-Barnum et al.   NATURE

Efficacy, immunogenicity, and safety of an oral influenza vaccine: a placebo-controlled and active-controlled phase 2 human challenge study

(2020) David Liebowitz et al.   LANCET INFECTIOUS DISEASES

Pathogenesis of influenza A(H7N9) virus in aged non-human primates

(2020) Satoshi Fukuyama et al.   JOURNAL OF INFECTIOUS DISEASES

A Multi-Targeting, Nucleoside-Modified mRNA Influenza Virus Vaccine Provides Broad Protection in Mice

(2020) Alec W. Freyn et al.   MOLECULAR THERAPY

Experimental Infection Using Mouse-Adapted Influenza B Virus in a Mouse Model

(2020) Elena Prokopyeva et al.   Viruses-Basel

Tracking progress in universal influenza vaccine development

(2020) Julie Ostrowsky et al.   Current Opinion in Virology

Characterizing Emerging Canine H3 Influenza Viruses

(2020) Luis Martinez-Sobrido et al.   PLoS Pathogens

Quantitative aerobiologic analysis of an influenza human challenge‐transmission trial

(2020) Paul Jacob Bueno de Mesquita et al.   INDOOR AIR

Inactivated pandemic 2009 H1N1 influenza A virus human vaccines have different efficacy after homologous challenge in the ferret model

(2020) Beatriz Vidaña et al.   Influenza and Other Respiratory Viruses

Pre-existing immunity to influenza virus hemagglutinin stalk might drive selection for antibody-escape mutant viruses in a human challenge model

(2020) Jae-Keun Park et al.   NATURE MEDICINE

Prevalent Eurasian avian-like H1N1 swine influenza virus with 2009 pandemic viral genes facilitating human infection

(2020) Honglei Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Host–Pathogen Responses to Pandemic Influenza H1N1pdm09 in a Human Respiratory Airway Model

(2020) Elizabeth A. Pharo et al.   Viruses-Basel

T-cell responses following Natural Influenza Infection or Vaccination in Solid Organ Transplant Recipients

(2020) Arnaud G. L’Huillier et al.   Scientific Reports

Minimal transmission in an influenza A (H3N2) human challenge-transmission model within a controlled exposure environment

(2020) Jonathan S. Nguyen-Van-Tam et al.   PLoS Pathogens

Characterization of humoral immune responses and degree of protection induced by influenza vaccine in cotton rats: Effects of low vaccine dose and single vs booster vaccination

(2020) Yoshita Bhide et al.   Immunity Inflammation and Disease

Influenza A Virus in Swine: Epidemiology, Challenges and Vaccination Strategies

(2020) José Carlos Mancera Gracia et al.   Frontiers in Veterinary Science

A chimeric hemagglutinin-based universal influenza virus vaccine approach induces broad and long-lasting immunity in a randomized, placebo-controlled phase I trial

(2020) Raffael Nachbagauer et al.   NATURE MEDICINE

Multiple amino acid substitutions involved in the adaption of three avian-origin H7N9 influenza viruses in mice

(2019) Jianru Qin et al.   Virology Journal

The Role of M2e in the Development of Universal Influenza Vaccines

(2019) Xavier Saelens   JOURNAL OF INFECTIOUS DISEASES

Influenza virus infection as well as immunization with DNA encoding haemagglutinin protein induces potent antibody-dependent phagocytosis (ADP) and monocyte infection-enhancing responses in macaques

(2019) Gerrit Koopman et al.   JOURNAL OF GENERAL VIROLOGY

A Dose Finding Study of a Wild-Type Influenza A/H3N2 virus in a Healthy Volunteer Human Challenge Model

(2019) Alison Han et al.   CLINICAL INFECTIOUS DISEASES

Development of Influenza B Universal Vaccine Candidates Using the “Mosaic” Hemagglutinin Approach

(2019) Weina Sun et al.   JOURNAL OF VIROLOGY

Mucosal Immunity against Neuraminidase Prevents Influenza B Virus Transmission in Guinea Pigs

(2019) Meagan McMahon et al.   mBio

The Future of Flu: A Review of the Human Challenge Model and Systems Biology for Advancement of Influenza Vaccinology

(2019) Amy Caryn Sherman et al.   Frontiers in Cellular and Infection Microbiology

Novel correlates of protection against pandemic H1N1 influenza A virus infection

(2019) Sophia Ng et al.   NATURE MEDICINE

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

(2019) Wen-Chun Liu et al.   Frontiers in Immunology

A mosaic hemagglutinin-based influenza virus vaccine candidate protects mice from challenge with divergent H3N2 strains

(2019) Felix Broecker et al.   npj Vaccines

Sequential Immunization with Universal Live Attenuated Influenza Vaccine Candidates Protects Ferrets against a High-Dose Heterologous Virus Challenge

(2019) Irina Isakova-Sivak et al.   Vaccines

Meeting report: Convening on the influenza human viral challenge model for universal influenza vaccines, Part 1: Value; challenge virus selection; regulatory, industry and ethical considerations; increasing standardization, access and capacity

(2019) Bruce L. Innis et al.   VACCINE

Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge

(2019) Meagan McMahon et al.   Frontiers in Immunology

Syrian Hamster as an Animal Model for the Study on Infectious Diseases

(2019) Jinxin Miao et al.   Frontiers in Immunology

Comparison of Human H3N2 Antibody Responses Elicited by Egg-Based, Cell-Based, and Recombinant Protein–Based Influenza Vaccines During the 2017–2018 Season

(2019) Sigrid Gouma et al.   CLINICAL INFECTIOUS DISEASES

Spread of Antigenically Drifted Influenza A(H3N2) Viruses and Vaccine Effectiveness in the United States During the 2018–2019 Season

(2019) Brendan Flannery et al.   JOURNAL OF INFECTIOUS DISEASES

Mouse-adapted H9N2 avian influenza virus causes systemic infection in mice

(2019) Zhe Hu et al.   Virology Journal

Synergistic PA and HA mutations confer mouse adaptation of a contemporary A/H3N2 influenza virus

(2019) Mariana Baz et al.   Scientific Reports

A Guide for the Use of the Ferret Model for Influenza Virus Infection

(2019) Jessica A. Belser et al.   AMERICAN JOURNAL OF PATHOLOGY

Influenza in High-Risk Hosts—Lessons Learned from Animal Models

(2019) Rebekah Honce et al.   Cold Spring Harbor Perspectives in Medicine

OUP accepted manuscript

(2018)   AMERICAN JOURNAL OF EPIDEMIOLOGY

Pregnancy preserves pulmonary function following influenza virus infection in C57BL/6 mice

(2018) Meghan S. Vermillion et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

(2018) Yao-Qing Chen et al.   CELL

A Lipid/DNA Adjuvant–Inactivated Influenza Virus Vaccine Protects Rhesus Macaques From Uncontrolled Virus Replication After Heterosubtypic Influenza A Virus Challenge

(2018) Timothy D Carroll et al.   JOURNAL OF INFECTIOUS DISEASES

A Universal Influenza Vaccine: The Strategic Plan for the National Institute of Allergy and Infectious Diseases

(2018) Emily J Erbelding et al.   JOURNAL OF INFECTIOUS DISEASES

Of mice and men: the host response to influenza virus infection

(2018) Heike Kollmus et al.   MAMMALIAN GENOME

From Original Antigenic Sin to the Universal Influenza Virus Vaccine

(2018) Carole Henry et al.   TRENDS IN IMMUNOLOGY

Towards a universal influenza vaccine: different approaches for one goal

(2018) Giuseppe A. Sautto et al.   Virology Journal

Moving Forward: Recent Developments for the Ferret Biomedical Research Model

(2018) Randy A. Albrecht et al.   mBio

Development of a preclinical humanized mouse model to evaluate acute toxicity of an influenza vaccine

(2018) Eita Sasaki et al.   Oncotarget

Adjuvanted influenza vaccines

(2018) John S. Tregoning et al.   Human Vaccines & Immunotherapeutics

Seasonal influenza vaccine in immunocompromised persons

(2018) Mohammad Bosaeed et al.   Human Vaccines & Immunotherapeutics

Aged Mice are More Resistant to Influenza Virus Infection due to Reduced Inflammation and Lung Pathology

(2018) Jiao Lu et al.   Aging and Disease

Production of Genetically Engineered Golden Syrian Hamsters by Pronuclear Injection of the CRISPR/Cas9 Complex

(2018) Rong Li et al.   Jove-Journal of Visualized Experiments

Host Immune Response to Influenza A Virus Infection

(2018) Xiaoyong Chen et al.   Frontiers in Immunology

Mouse Models of Influenza Infection with Circulating Strains to Test Seasonal Vaccine Efficacy

(2018) Helen T. Groves et al.   Frontiers in Immunology

Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults

(2018) L. Coughlan et al.   EBioMedicine

Using the Influenza Patient-reported Outcome (FLU-PRO) diary to evaluate symptoms of influenza viral infection in a healthy human challenge model

(2018) Alison Han et al.   BMC INFECTIOUS DISEASES

Split inactivated COBRA vaccine elicits protective antibodies against H1N1 and H3N2 influenza viruses

(2018) James D. Allen et al.   PLoS One

Nucleoside-modified mRNA immunization elicits influenza virus hemagglutinin stalk-specific antibodies

(2018) Norbert Pardi et al.   Nature Communications

Universal influenza vaccines: from viruses to nanoparticles

(2018) Ye Wang et al.   Expert Review of Vaccines

Preclinical evaluation of the efficacy of an H5N8 vaccine candidate (IDCDC-RG43A) in mouse and ferret models for pandemic preparedness

(2018) Ju Hwan Jeong et al.   VACCINE

Mini-HA Is Superior to Full Length Hemagglutinin Immunization in Inducing Stem-Specific Antibodies and Protection Against Group 1 Influenza Virus Challenges in Mice

(2018) Joan E. M. van der Lubbe et al.   Frontiers in Immunology

Broadened immunity against influenza by vaccination with computationally designed influenza virus N1 neuraminidase constructs

(2018) E. R. Job et al.   npj Vaccines

Nonhuman Primate Models of Respiratory Disease: Past, Present, and Future

(2017) Lisa A Miller et al.   ILAR JOURNAL

Dysregulated T-Helper Type 1 (Th1):Th2 Cytokine Profile and Poor Immune Response in Pregnant Ferrets Infected With 2009 Pandemic Influenza A(H1N1) Virus

(2017) Sun-Woo Yoon et al.   JOURNAL OF INFECTIOUS DISEASES

Syrian hamster as an animal model for the study of human influenza virus infection

(2017) Kiyoko Iwatsuki-Horimoto et al.   JOURNAL OF VIROLOGY

Chimeric Hemagglutinin Constructs Induce Broad Protection against Influenza B Virus Challenge in the Mouse Model

(2017) Megan E. Ermler et al.   JOURNAL OF VIROLOGY

Safe Recombinant Outer Membrane Vesicles that Display M2e Elicit Heterologous Influenza Protection

(2017) Hannah C. Watkins et al.   MOLECULAR THERAPY

Efficient Targeting and Activation of Antigen-Presenting Cells In Vivo after Modified mRNA Vaccine Administration in Rhesus Macaques

(2017) Frank Liang et al.   MOLECULAR THERAPY

A mouse model of vitamin D insufficiency: is there a relationship between 25(OH) vitamin D levels and obesity?

(2017) Kenneth L. Seldeen et al.   Nutrition & Metabolism

Multigenic DNA vaccine induces protective cross-reactive T cell responses against heterologous influenza virus in nonhuman primates

(2017) Merika T. Koday et al.   PLoS One

Contemporary H3N2 influenza viruses have a glycosylation site that alters binding of antibodies elicited by egg-adapted vaccine strains

(2017) Seth J. Zost et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prevnar-13 vaccine failure in a mouse model for vitamin A deficiency

(2017) Rhiannon R. Penkert et al.   VACCINE

Adjuvanting an inactivated influenza vaccine with conjugated R848 improves the level of antibody present at 6 months in a nonhuman primate neonate model

(2017) Beth C. Holbrook et al.   VACCINE

Evaluation of the innate immune responses to influenza and live-attenuated influenza vaccine infection in primary differentiated human nasal epithelial cells

(2017) Adriana Forero et al.   VACCINE

Maternal antibodies protect offspring from severe influenza infection and do not lead to detectable interference with subsequent offspring immunization

(2017) Joan E. M. van der Lubbe et al.   Virology Journal

H1N1 influenza virus infection results in adverse pregnancy outcomes by disrupting tissue-specific hormonal regulation

(2017) Elizabeth Q. Littauer et al.   PLoS Pathogens

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

(2017) Raffael Nachbagauer et al.   npj Vaccines

Vitamin Supplementation at the Time of Immunization with a Cold-Adapted Influenza Virus Vaccine Corrects Poor Mucosal Antibody Responses in Mice Deficient for Vitamins A and D

(2016) S. L. Surman et al.   Clinical and Vaccine Immunology

A plant-derived quadrivalent virus like particle influenza vaccine induces cross-reactive antibody and T cell response in healthy adults

(2016) Stéphane Pillet et al.   CLINICAL IMMUNOLOGY

Heads, stalks and everything else: how can antibodies eradicate influenza as a human disease?

(2016) Karlynn E Neu et al.   CURRENT OPINION IN IMMUNOLOGY

Fluzone® High-Dose Influenza Vaccine

(2016) Corwin A. Robertson et al.   Expert Review of Vaccines

Evaluating influenza vaccines: progress and perspectives

(2016) Elena Gianchecchi et al.   Future Virology

Adaptation of influenza A(H1N1)pdm09 virus in experimental mouse models

(2016) E.A. Prokopyeva et al.   INFECTION GENETICS AND EVOLUTION

An overview of the regulation of influenza vaccines in the United States

(2016) Jerry P. Weir et al.   Influenza and Other Respiratory Viruses

Vaccine-associated enhanced respiratory disease is influenced by haemagglutinin and neuraminidase in whole inactivated influenza virus vaccines

(2016) Daniela S. Rajão et al.   JOURNAL OF GENERAL VIROLOGY

A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model

(2016) Beth C. Holbrook et al.   JOURNAL OF IMMUNOLOGY

Design and Characterization of a Computationally Optimized Broadly Reactive Hemagglutinin Vaccine for H1N1 Influenza Viruses

(2016) Donald M. Carter et al.   JOURNAL OF VIROLOGY

Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection

(2016) Anthony DiPiazza et al.   JOURNAL OF VIROLOGY

The Microminipig as an Animal Model for Influenza A Virus Infection

(2016) Kiyoko Iwatsuki-Horimoto et al.   JOURNAL OF VIROLOGY

Complexities in Ferret Influenza Virus Pathogenesis and Transmission Models

(2016) Jessica A. Belser et al.   MICROBIOLOGY AND MOLECULAR BIOLOGY REVIEWS

Accelerating Influenza Research: Vaccines, Antivirals, Immunomodulators and Monoclonal Antibodies. The Manufacture of a New Wild-Type H3N2 Virus for the Human Viral Challenge Model

(2016) Daniel J. Fullen et al.   PLoS One

Influenza pathogenicity during pregnancy in women and animal models

(2016) Debby van Riel et al.   Seminars in Immunopathology

Adjuvanting an inactivated influenza vaccine with flagellin improves the function and quantity of the long-term antibody response in a nonhuman primate neonate model

(2016) Beth C. Holbrook et al.   VACCINE

Evaluation of Antihemagglutinin and Antineuraminidase Antibodies as Correlates of Protection in an Influenza A/H1N1 Virus Healthy Human Challenge Model

(2016) Matthew J. Memoli et al.   mBio

Preclinical evaluation of the safety and pathogenicity of a live attenuated recombinant influenza A/H7N9 seed strain and corresponding MF59-adjuvanted split vaccine

(2016) Huilin Ou et al.   Oncotarget

Origins of the 2009 H1N1 influenza pandemic in swine in Mexico

(2016) Ignacio Mena et al.   eLife

The use of nonhuman primates in research on seasonal, pandemic and avian influenza, 1893–2014

(2015) A. Sally Davis et al.   ANTIVIRAL RESEARCH

CRISPR/Cas9-mediated genome engineering of the ferret

(2015) Zhaohui Kou et al.   CELL RESEARCH

Current and next generation influenza vaccines: Formulation and production strategies

(2015) Peter C. Soema et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

Swine as a Model for Influenza A Virus Infection and Immunity

(2015) D. S. Rajao et al.   ILAR JOURNAL

Antibody to Influenza Virus Neuraminidase: An Independent Correlate of Protection

(2015) Arnold S. Monto et al.   JOURNAL OF INFECTIOUS DISEASES

Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

(2015) Raffael Nachbagauer et al.   JOURNAL OF VIROLOGY

Replication of live attenuated cold-adapted H2N2 influenza virus vaccine candidates in non human primates

(2015) Andrew J. Broadbent et al.   VACCINE

Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection

(2015) Beth C. Holbrook et al.   VIROLOGY

Vaccination with Adjuvanted Recombinant Neuraminidase Induces Broad Heterologous, but Not Heterosubtypic, Cross-Protection against Influenza Virus Infection in Mice

(2015) Teddy John Wohlbold et al.   mBio

Cocktail of H5N1 COBRA HA vaccines elicit protective antibodies against H5N1 viruses from multiple clades

(2015) Corey J Crevar et al.   Human Vaccines & Immunotherapeutics

Influenza Transmission in the Mother-Infant Dyad Leads to Severe Disease, Mammary Gland Infection, and Pathogenesis by Regulating Host Responses

(2015) Stéphane G. Paquette et al.   PLoS Pathogens

Prospects of HA-Based Universal Influenza Vaccine

(2015) Anwar M. Hashem   Biomed Research International

Influenza Virus Propagation in Embryonated Chicken Eggs

(2015) Rena Brauer et al.   Jove-Journal of Visualized Experiments

Pandemic Swine-Origin H1N1 Influenza Virus Replicates to Higher Levels and Induces More Fever and Acute Inflammatory Cytokines in Cynomolgus versus Rhesus Monkeys and Can Replicate in Common Marmosets

(2015) Petra Mooij et al.   PLoS One

Environmental Conditions Affect Exhalation of H3N2 Seasonal and Variant Influenza Viruses and Respiratory Droplet Transmission in Ferrets

(2015) Kortney M. Gustin et al.   PLoS One

Humans and Ferrets with Prior H1N1 Influenza Virus Infections Do Not Exhibit Evidence of Original Antigenic Sin after Infection or Vaccination with the 2009 Pandemic H1N1 Influenza Virus

(2014) Christopher D. O'Donnell et al.   Clinical and Vaccine Immunology

Glycomic Characterization of Respiratory Tract Tissues of Ferrets

(2014) Nan Jia et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Effects of Aging on Influenza Virus Infection Dynamics

(2014) E. A. Hernandez-Vargas et al.   JOURNAL OF VIROLOGY

Introductions and Evolution of Human-Origin Seasonal Influenza A Viruses in Multinational Swine Populations

(2014) M. I. Nelson et al.   JOURNAL OF VIROLOGY

Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

(2014) F. Krammer et al.   JOURNAL OF VIROLOGY

Influenza Virus Reservoirs and Intermediate Hosts: Dogs, Horses, and New Possibilities for Influenza Virus Exposure of Humans

(2014) Colin R. Parrish et al.   JOURNAL OF VIROLOGY

The draft genome sequence of the ferret (Mustela putorius furo) facilitates study of human respiratory disease

(2014) Xinxia Peng et al.   NATURE BIOTECHNOLOGY

Efficacy of High-Dose versus Standard-Dose Influenza Vaccine in Older Adults

(2014) Carlos A. DiazGranados et al.   NEW ENGLAND JOURNAL OF MEDICINE

Low Dose Influenza Virus Challenge in the Ferret Leads to Increased Virus Shedding and Greater Sensitivity to Oseltamivir

(2014) Anthony C. Marriott et al.   PLoS One

Impaired heterologous immunity in aged ferrets during sequential influenza A H1N1 infection

(2014) Stéphane G. Paquette et al.   VIROLOGY

Traditional and New Influenza Vaccines

(2013) S.-S. Wong et al.   CLINICAL MICROBIOLOGY REVIEWS

The evolving history of influenza viruses and influenza vaccines

(2013) Claude Hannoun   Expert Review of Vaccines

Efficacy of Influenza Vaccination of Elderly Rhesus Macaques Is Dramatically Improved by Addition of a Cationic Lipid/DNA Adjuvant

(2013) T. D. Carroll et al.   JOURNAL OF INFECTIOUS DISEASES

Risk Assessment of H2N2 Influenza Viruses from the Avian Reservoir

(2013) J. C. Jones et al.   JOURNAL OF VIROLOGY

Standard Trivalent Influenza Virus Protein Vaccination Does Not Prime Antibody-Dependent Cellular Cytotoxicity in Macaques

(2013) S. Jegaskanda et al.   JOURNAL OF VIROLOGY

Hemagglutinin Stalk-Based Universal Vaccine Constructs Protect against Group 2 Influenza A Viruses

(2013) I. Margine et al.   JOURNAL OF VIROLOGY

Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

(2013) Richard D Antrobus et al.   MOLECULAR THERAPY

Antiviral Responses by Swine Primary Bronchoepithelial Cells Are Limited Compared to Human Bronchoepithelial Cells Following Influenza Virus Infection

(2013) Mary J. Hauser et al.   PLoS One

Early Host Responses of Seasonal and Pandemic Influenza A Viruses in Primary Well-Differentiated Human Lung Epithelial Cells

(2013) Rachael L. Gerlach et al.   PLoS One

A Novel Nonhuman Primate Model for Influenza Transmission

(2013) Louise H. Moncla et al.   PLoS One

Severe pathogenesis of influenza B virus in pregnant mice

(2013) Jeong Cheol Kim et al.   VIROLOGY

Risk factors associated with severe manifestations of 2009 pandemic influenza A (H1N1) infection in China: a case–control study

(2013) Yan-yan Ren et al.   Virology Journal

Assessing the fitness of distinct clades of influenza A (H9N2) viruses

(2013)   Emerging Microbes & Infections

Global transmission of influenza viruses from humans to swine

(2012) M. I. Nelson et al.   JOURNAL OF GENERAL VIROLOGY

Protein Energy Malnutrition Decreases Immunity and Increases Susceptibility to Influenza Infection in Mice

(2012) Andrew K. Taylor et al.   JOURNAL OF INFECTIOUS DISEASES

Comparative Study of Influenza Virus Replication in MDCK Cells and in Primary Cells Derived from Adenoids and Airway Epithelium

(2012) N. A. Ilyushina et al.   JOURNAL OF VIROLOGY

An mRNA vaccine for influenza

(2012) Sook-San Wong et al.   NATURE BIOTECHNOLOGY

Decoding the Distribution of Glycan Receptors for Human-Adapted Influenza A Viruses in Ferret Respiratory Tract

(2012) Akila Jayaraman et al.   PLoS One

The impact of obesity on the immune response to infection

(2012) J. Justin Milner et al.   PROCEEDINGS OF THE NUTRITION SOCIETY

The economic value of a quadrivalent versus trivalent influenza vaccine

(2012) Bruce Y. Lee et al.   VACCINE

Immunization with live virus vaccine protects highly susceptible DBA/2J mice from lethal influenza A H1N1 infection

(2012) Leonie Dengler et al.   Virology Journal

Influenza viruses

(2012) Leslie A. Reperant et al.   Human Vaccines & Immunotherapeutics

The rationale for quadrivalent influenza vaccines

(2012) Christopher S. Ambrose et al.   Human Vaccines & Immunotherapeutics

Intranasal Immunization of Ferrets with Commercial Trivalent Influenza Vaccines Formulated in a Nanoemulsion-Based Adjuvant

(2011) Tarek Hamouda et al.   Clinical and Vaccine Immunology

The ferret as a model organism to study influenza A virus infection

(2011) J. A. Belser et al.   Disease Models & Mechanisms

Animal models to assess the toxicity, immunogenicity and effectiveness of candidate influenza vaccines

(2011) Maryna C Eichelberger et al.   Expert Opinion on Drug Metabolism & Toxicology

Diet-Induced Obesity Dramatically Reduces the Efficacy of a 2009 Pandemic H1N1 Vaccine in a Mouse Model

(2011) Yong-Hoon Kim et al.   JOURNAL OF INFECTIOUS DISEASES

Influenza Hemagglutination-Inhibition Antibody Titer as a Correlate of Vaccine-Induced Protection

(2011) Suzanne E. Ohmit et al.   JOURNAL OF INFECTIOUS DISEASES

Use of a Human Influenza Challenge Model to Assess Person-to-Person Transmission: Proof-of-Concept Study

(2011) Ben Killingley et al.   JOURNAL OF INFECTIOUS DISEASES

Fatal Outcome of Pandemic H1N1 2009 Influenza Virus Infection Is Associated with Immunopathology and Impaired Lung Repair, Not Enhanced Viral Burden, in Pregnant Mice

(2011) G. Marcelin et al.   JOURNAL OF VIROLOGY

The DBA.2 Mouse Is Susceptible to Disease following Infection with a Broad, but Limited, Range of Influenza A and B Viruses

(2011) N. Pica et al.   JOURNAL OF VIROLOGY

Potential role of human challenge studies for investigation of influenza transmission

(2011) Ben Killingley et al.   LANCET INFECTIOUS DISEASES

Adaption of Seasonal H1N1 Influenza Virus in Mice

(2011) Lili Xu et al.   PLoS One

Efficacy of seasonal live attenuated influenza vaccine against virus replication and transmission of a pandemic 2009 H1N1 virus in ferrets

(2011) Melissa B. Pearce et al.   VACCINE

Vaccine-specific antibody secreting cells are a robust early marker of LAIV-induced B-cell response in ferrets

(2011) Anu Cherukuri et al.   VACCINE

Efficacy of trivalent inactivated influenza vaccines in the cotton rat Sigmodon hispidus model

(2011) Kevin Yim et al.   VACCINE

Humanized mouse models to study human diseases

(2011) Michael A Brehm et al.   Current Opinion in Endocrinology Diabetes and Obesity

A Live Attenuated H7N7 Candidate Vaccine Virus Induces Neutralizing Antibody That Confers Protection from Challenge in Mice, Ferrets, and Monkeys

(2010) J.-Y. Min et al.   JOURNAL OF VIROLOGY

Wild Type and Mutant 2009 Pandemic Influenza A (H1N1) Viruses Cause More Severe Disease and Higher Mortality in Pregnant BALB/c Mice

(2010) Kwok-Hung Chan et al.   PLoS One

Guinea Pig Model for Evaluating the Potential Public Health Risk of Swine and Avian Influenza Viruses

(2010) Yipeng Sun et al.   PLoS One

Induction of Broadly Neutralizing H1N1 Influenza Antibodies by Vaccination

(2010) C.-J. Wei et al.   SCIENCE

The need for quadrivalent vaccine against seasonal influenza

(2010) Robert B. Belshe   VACCINE

Impact of prior seasonal influenza vaccination and infection on pandemic A (H1N1) influenza virus replication in ferrets

(2010) A.H. Ellebedy et al.   VACCINE

Serological characterization of guinea pigs infected with H3N2 human influenza or immunized with hemagglutinin protein

(2010) Ruth V Bushnell et al.   Virology Journal

Animal Models for Influenza Virus Pathogenesis and Transmission

(2010) Nicole M. Bouvier et al.   Viruses-Basel

Influenza Virus Vaccine Based on the Conserved Hemagglutinin Stalk Domain

(2010) J. Steel et al.   mBio

High infectivity and pathogenicity of influenza A virus via aerosol and droplet transmission

(2010) Peter F.M. Teunis et al.   Epidemics

The cotton rat model of respiratory viral infections

(2009) Marina S. Boukhvalova et al.   BIOLOGICALS

Animal models for the preclinical evaluation of candidate influenza vaccines

(2009) Rogier Bodewes et al.   Expert Review of Vaccines

A cell-based H7N1 split influenza virion vaccine confers protection in mouse and ferret challenge models

(2009) Rebecca J. Cox et al.   Influenza and Other Respiratory Viruses

Pathogenesis and transmission of the novel swine-origin influenza virus A/H1N1 after experimental infection of pigs

(2009) E. Lange et al.   JOURNAL OF GENERAL VIROLOGY

Preclinical Evaluation of a Replication-Deficient Intranasal ΔNS1 H5N1 Influenza Vaccine

(2009) Julia Romanova et al.   PLoS One

T-cell immunosenescence: lessons learned from mouse models of aging

(2009) Alexander C. Maue et al.   TRENDS IN IMMUNOLOGY

M2e-based universal influenza A vaccine

(2009) Walter Fiers et al.   VACCINE

Subcutaneous inoculation of a whole virus particle vaccine prepared from a non-pathogenic virus library induces protective immunity against H7N7 highly pathogenic avian influenza virus in cynomolgus macaques

(2009) Yasushi Itoh et al.   VACCINE

Multiple amino acid substitutions are involved in the adaptation of H9N2 avian influenza virus to mice

(2009) Rui Wu et al.   VETERINARY MICROBIOLOGY

Detection of expression of influenza virus receptors in tissues of BALB/c mice by histochemistry

(2009) Zhang-Yong Ning et al.   VETERINARY RESEARCH COMMUNICATIONS

Broad influenza-specific CD8+ T-cell responses in humanized mice vaccinated with influenza virus vaccines

(2008) C. I. Yu et al.   BLOOD

Cloning, expression and immunoassay detection of ferret IFN-γ

(2008) Atsuo Ochi et al.   DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY

Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferrets

(2008) Xingshen Sun et al.   JOURNAL OF CLINICAL INVESTIGATION

Screening monoclonal antibodies for cross-reactivity in the ferret model of influenza infection

(2008) John A. Rutigliano et al.   JOURNAL OF IMMUNOLOGICAL METHODS

Recombinant Modified Vaccinia Virus Ankara Expressing the Hemagglutinin Gene Confers Protection against Homologous and Heterologous H5N1 Influenza Virus Infections in Macaques

(2008) J. H. C. M. Kreijtz et al.   JOURNAL OF INFECTIOUS DISEASES

Energy Restriction Impairs Natural Killer Cell Function and Increases the Severity of Influenza Infection in Young Adult Male C57BL/6 Mice

(2008) Barry W. Ritz et al.   JOURNAL OF NUTRITION

Molecular Cloning and Phylogenetic Analysis of Inflammatory Cytokines of the Ferret (Mustela putorius furo)

(2008) Makoto NAKATA et al.   JOURNAL OF VETERINARY MEDICAL SCIENCE

Adaptation of human influenza H3N2 virus in a mouse pneumonitis model: insights into viral virulence, tissue tropism and host pathogenesis

(2008) T NARASARAJU et al.   MICROBES AND INFECTION

Review of clinical symptoms and spectrum in humans with influenza A/H5N1 infection

(2008) David S.-C. HUI   RESPIROLOGY

The biology of influenza viruses

(2008) Nicole M. Bouvier et al.   VACCINE

Cloning, expression and characterization of ferret CXCL10

(2007) Ali Danesh et al.   MOLECULAR IMMUNOLOGY

Failure of protection and enhanced pneumonia with a US H1N2 swine influenza virus in pigs vaccinated with an inactivated classical swine H1N1 vaccine

(2007) Amy L. Vincent et al.   VETERINARY MICROBIOLOGY