A Novel R848-Conjugated Inactivated Influenza Virus Vaccine Is Efficacious and Safe in a Neonate Nonhuman Primate Model

Inclusion of Flagellin during Vaccination against Influenza Enhances Recall Responses in Nonhuman Primate Neonates

(2015) Jong R. Kim et al.   JOURNAL OF VIROLOGY

In vivo characterization of the physicochemical properties of polymer-linked TLR agonists that enhance vaccine immunogenicity

(2015) Geoffrey M Lynn et al.   NATURE BIOTECHNOLOGY

Nonhuman primate infants have an impaired respiratory but not systemic IgG antibody response following influenza virus infection

(2015) Beth C. Holbrook et al.   VIROLOGY

Activated Human Neonatal CD8+ T Cells Are Subject to Immunomodulation by Direct TLR2 or TLR5 Stimulation

(2014) M. McCarron et al.   JOURNAL OF IMMUNOLOGY

T Regulatory Cells Contribute to the Attenuated Primary CD8+ and CD4+ T Cell Responses to Herpes Simplex Virus Type 2 in Neonatal Mice

(2014) M. A. Fernandez et al.   JOURNAL OF IMMUNOLOGY

Unleashing the potential of NOD- and Toll-like agonists as vaccine adjuvants

(2014) C. Maisonneuve et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The use of Toll-like receptor 7/8 agonists as vaccine adjuvants

(2013) John P Vasilakos et al.   Expert Review of Vaccines

Neonatal lung immune responses show a shift of cytokines and transcription factors toward Th2 and a deficit in conventional and plasmacytoid dendritic cells

(2011) Xavier Roux et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Induction of a potent immune response in the elderly using the TLR-5 agonist, flagellin, with a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125, STF2.HA1 SI)

(2011) David N. Taylor et al.   VACCINE

Safety and immunogenicity of a recombinant M2e–flagellin influenza vaccine (STF2.4xM2e) in healthy adults

(2011) Christine B. Turley et al.   VACCINE

Using 3 TLR ligands as a combination adjuvant induces qualitative changes in T cell responses needed for antiviral protection in mice

(2010) Qing Zhu et al.   JOURNAL OF CLINICAL INVESTIGATION

"Default" Generation of Neonatal Regulatory T Cells

(2010) G. Wang et al.   JOURNAL OF IMMUNOLOGY

Enhanced Immunogenicity of Stabilized Trimeric Soluble Influenza Hemagglutinin

(2010) William C. Weldon et al.   PLoS One

Analysis of in vivo dynamics of influenza virus infection in mice using a GFP reporter virus

(2010) B. Manicassamy et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Lung homing CTLs and their proliferation ability are important correlates of vaccine protection against influenza

(2010) Jianping Lin et al.   VACCINE

The rational use of influenza vaccines in healthy children and children with underlying conditions

(2009) Susanna Esposito et al.   CURRENT OPINION IN INFECTIOUS DISEASES

Neonatal Innate TLR-Mediated Responses Are Distinct from Those of Adults

(2009) T. R. Kollmann et al.   JOURNAL OF IMMUNOLOGY

Neonatal immunity: faulty T-helpers and the shortcomings of dendritic cells

(2009) Habib Zaghouani et al.   TRENDS IN IMMUNOLOGY

Immunization of young African green monkeys with OprF epitope 8–OprI–type A- and B-flagellin fusion proteins promotes the production of protective antibodies against nonmucoid Pseudomonasaeruginosa

(2009) Eric T. Weimer et al.   VACCINE

Cord blood dendritic cells prevent the differentiation of naïve T-helper cells towards Th1 irrespective of their subtype

(2008) Nadereh Naderi et al.   CLINICAL AND EXPERIMENTAL MEDICINE

Delayed maturation of an IL-12–producing dendritic cell subset explains the early Th2 bias in neonatal immunity

(2008) Hyun-Hee Lee et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Safety and Immunogenicity of Trivalent Inactivated Influenza Vaccine in Infants

(2008) Natasha B. Halasa et al.   JOURNAL OF INFECTIOUS DISEASES

FDA/NIH/WHO public workshop on immune correlates of protection against influenza A viruses in support of pandemic vaccine development, Bethesda, Maryland, US, December 10–11, 2007

(2008) Maryna Eichelberger et al.   VACCINE

Alum boosts TH2-type antibody responses to whole-inactivated virus influenza vaccine in mice but does not confer superior protection

(2008) Laura Bungener et al.   VACCINE

Expression and function of Toll-like receptors on dendritic cells and other antigen presenting cells from non-human primates

(2008) Chutitorn Ketloy et al.   VETERINARY IMMUNOLOGY AND IMMUNOPATHOLOGY