Evaluating influenza vaccines: progress and perspectives

Recombinant M2e outer membrane vesicle vaccines protect against lethal influenza A challenge in BALB/c mice

(2016) C. Garrett Rappazzo et al.   VACCINE

Prospects for Broadly Protective Influenza Vaccines

(2015) John Jay Treanor   AMERICAN JOURNAL OF PREVENTIVE MEDICINE

Current and next generation influenza vaccines: Formulation and production strategies

(2015) Peter C. Soema et al.   EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS

H5N1 influenza virulence, pathogenicity and transmissibility: what do we know?

(2015) Gabriele Neumann   Future Virology

Refining the approach to vaccines against influenza A viruses with pandemic potential

(2015) Rita Czako et al.   Future Virology

Engineering of the PapMV vaccine platform with a shortened M2e peptide leads to an effective one dose influenza vaccine

(2015) Damien Carignan et al.   VACCINE

Considerations of strategies to provide influenza vaccine year round

(2015) Philipp Lambach et al.   VACCINE

Persistence and avidity maturation of antibodies to A(H1N1)pdm09 in healthcare workers following repeated annual vaccinations

(2015) Synnøve Eidem et al.   VACCINE

Quantifying the risk of pandemic influenza virus evolution by mutation and re-assortment

(2015) Leslie A. Reperant et al.   VACCINE

A novel peptide-based pan-influenza A vaccine: A double blind, randomised clinical trial of immunogenicity and safety

(2015) James N. Francis et al.   VACCINE

Strengthening the influenza vaccine virus selection and development process

(2015) William K. Ampofo et al.   VACCINE

Matrix-M™ adjuvation broadens protection induced by seasonal trivalent virosomal influenza vaccine

(2015) Freek Cox et al.   Virology Journal

Safety and immunogenicity of influenza whole inactivated virus vaccines: A phase I randomized clinical trial

(2015) Renée A J van Boxtel et al.   Human Vaccines & Immunotherapeutics

Prospects of HA-Based Universal Influenza Vaccine

(2015) Anwar M. Hashem   Biomed Research International

New small-molecule drug design strategies for fighting resistant influenza A

(2015) Zuyuan Shen et al.   Acta Pharmaceutica Sinica B

Mechanisms of Cross-protection by Influenza Virus M2-based Vaccines

(2015) Yu-Na Lee et al.   Immune Network

Identification, Characterization, and Natural Selection of Mutations Driving Airborne Transmission of A/H5N1 Virus

(2014) Martin Linster et al.   CELL

Development of live attenuated influenza vaccines against pandemic influenza strains

(2014) Kathleen L Coelingh et al.   Expert Review of Vaccines

Intranasal chitosan-DNA vaccines that protect across influenza virus subtypes

(2014) Chompoonuch Sawaengsak et al.   INTERNATIONAL JOURNAL OF PHARMACEUTICS

Epitope-based approaches to a universal influenza vaccine

(2014) Tanya Gottlieb et al.   JOURNAL OF AUTOIMMUNITY

Mucosal Polyinosinic-Polycytidylic Acid Improves Protection Elicited by Replicating Influenza Vaccines via Enhanced Dendritic Cell Function and T Cell Immunity

(2014) J. V. Perez-Giron et al.   JOURNAL OF IMMUNOLOGY

Airborne Transmission of Highly Pathogenic H7N1 Influenza Virus in Ferrets

(2014) T. C. Sutton et al.   JOURNAL OF VIROLOGY

Intranasal H5N1 Vaccines, Adjuvanted with Chitosan Derivatives, Protect Ferrets against Highly Pathogenic Influenza Intranasal and Intratracheal Challenge

(2014) Alex J. Mann et al.   PLoS One

Influenza M2 virus-like particles confer a broader range of cross protection to the strain-specific pre-existing immunity

(2014) Min-Chul Kim et al.   VACCINE

Priming by a novel universal influenza vaccine (Multimeric-001)—A gateway for improving immune response in the elderly population

(2014) Jacob Atsmon et al.   VACCINE

Molecular Markers of Influenza B Lineages and Clades

(2014) Rosaria Arvia et al.   Viruses-Basel

Options and Obstacles for Designing a Universal Influenza Vaccine

(2014) Yo Jang et al.   Viruses-Basel

T Cell Responses to Viral Infections – Opportunities for Peptide Vaccination

(2014) Sietske Rosendahl Huber et al.   Frontiers in Immunology

Toward a Universal Influenza Virus Vaccine: Prospects and Challenges

(2013) Natalie Pica et al.   Annual Review of Medicine

Multiple heterologous M2 extracellular domains presented on virus-like particles confer broader and stronger M2 immunity than live influenza A virus infection

(2013) Min-Chul Kim et al.   ANTIVIRAL RESEARCH

Alternative Reassortment Events Leading to Transmissible H9N1 Influenza Viruses in the Ferret Model

(2013) J. B. Kimble et al.   JOURNAL OF VIROLOGY

Replication and Immunogenicity of Swine, Equine, and Avian H3 Subtype Influenza Viruses in Mice and Ferrets

(2013) M. Baz et al.   JOURNAL OF VIROLOGY

Safety and immunogenicity of an oral, replicating adenovirus serotype 4 vector vaccine for H5N1 influenza: a randomised, double-blind, placebo-controlled, phase 1 study

(2013) Marc Gurwith et al.   LANCET INFECTIOUS DISEASES

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

(2013) Richard D Antrobus et al.   MOLECULAR THERAPY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Human Infection with a Novel Avian-Origin Influenza A (H7N9) Virus

(2013) Rongbao Gao et al.   NEW ENGLAND JOURNAL OF MEDICINE

Emulsified Phosphatidylserine, Simple and Effective Peptide Carrier for Induction of Potent Epitope-Specific T Cell Responses

(2013) Toru Ichihashi et al.   PLoS One

H5N1 Hybrid Viruses Bearing 2009/H1N1 Virus Genes Transmit in Guinea Pigs by Respiratory Droplet

(2013) Y. Zhang et al.   SCIENCE

H7N9 Influenza Viruses Are Transmissible in Ferrets by Respiratory Droplet

(2013) Q. Zhang et al.   SCIENCE

The prospects and challenges of universal vaccines for influenza

(2013) Kanta Subbarao et al.   TRENDS IN MICROBIOLOGY

New World Bats Harbor Diverse Influenza A Viruses

(2013) Suxiang Tong et al.   PLoS Pathogens

Integrative genomic analysis of the human immune response to influenza vaccination

(2013) Luis M Franco et al.   eLife

A/H5N1 Prepandemic Influenza Vaccine (Whole Virion, Vero Cell-Derived, Inactivated) [Vepacel®]

(2012) Greg L. Plosker   DRUGS

Preflucel®: a Vero-cell culture-derived trivalent influenza vaccine

(2012) Candice Yuen-Yue Chan et al.   Expert Review of Vaccines

Towards tailored vaccine delivery: Needs, challenges and perspectives

(2012) Jean-Pierre Amorij et al.   JOURNAL OF CONTROLLED RELEASE

Influenza Surveillance in 15 Countries in Africa, 2006–2010

(2012) Jennifer Michalove Radin et al.   JOURNAL OF INFECTIOUS DISEASES

Global and regional mortality from 235 causes of death for 20 age groups in 1990 and 2010: a systematic analysis for the Global Burden of Disease Study 2010

(2012) Rafael Lozano et al.   LANCET

Preexisting influenza-specific CD4+ T cells correlate with disease protection against influenza challenge in humans

(2012) Tom M Wilkinson et al.   NATURE MEDICINE

AS03 Adjuvanted AH1N1 Vaccine Associated with an Abrupt Increase in the Incidence of Childhood Narcolepsy in Finland

(2012) Hanna Nohynek et al.   PLoS One

A distinct lineage of influenza A virus from bats

(2012) S. Tong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pandemic H1N1 influenza vaccine induces a recall response in humans that favors broadly cross-reactive memory B cells

(2012) G.-M. Li et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Airborne Transmission of Influenza A/H5N1 Virus Between Ferrets

(2012) S. Herfst et al.   SCIENCE

The Potential for Respiratory Droplet-Transmissible A/H5N1 Influenza Virus to Evolve in a Mammalian Host

(2012) C. A. Russell et al.   SCIENCE

A cell-based backup to speed up pandemic influenza vaccine production

(2012) Min-Shi Lee et al.   TRENDS IN MICROBIOLOGY

Development of VAX128, a recombinant hemagglutinin (HA) influenza-flagellin fusion vaccine with improved safety and immune response

(2012) David N. Taylor et al.   VACCINE

Adaptive pathways of zoonotic influenza viruses: From exposure to establishment in humans

(2012) Leslie A. Reperant et al.   VACCINE

Randomized clinical trial of immunogenicity and safety of a recombinant H1N1/2009 pandemic influenza vaccine containing Advax™ polysaccharide adjuvant

(2012) David L. Gordon et al.   VACCINE

Advax™, a polysaccharide adjuvant derived from delta inulin, provides improved influenza vaccine protection through broad-based enhancement of adaptive immune responses

(2012) Yoshikazu Honda-Okubo et al.   VACCINE

Adjuvanted influenza vaccines

(2012) Nicola Principi et al.   Human Vaccines & Immunotherapeutics

Live Attenuated Influenza Vaccine (FluMist®; Fluenz™)

(2011) Natalie J. Carter et al.   DRUGS

Current adjuvants and new perspectives in vaccine formulation

(2011) Emanuele Montomoli et al.   Expert Review of Vaccines

Fluzone®Intradermal vaccine: a promising new chance to increase the acceptability of influenza vaccination in adults

(2011) Filippo Ansaldi et al.   Expert Review of Vaccines

Pre-pandemic and pandemic influenza vaccines

(2011) Steven Rockman et al.   Human vaccines & immunotherapeutics

Improving influenza vaccine virus selectionReport of a WHO informal consultation held at WHO headquarters, Geneva, Switzerland, 14-16 June 2010

(2011) et al.   Influenza and Other Respiratory Viruses

Global burden of respiratory infections due to seasonal influenza in young children: a systematic review and meta-analysis

(2011) Harish Nair et al.   LANCET

Seasonal influenza epidemiology in sub-Saharan Africa: a systematic review

(2011) Bradford D Gessner et al.   LANCET INFECTIOUS DISEASES

Liposome-Coupled Peptides Induce Long-Lived Memory CD8+ T Cells Without CD4+ T Cells

(2011) Maiko Taneichi et al.   PLoS One

Cross-Protective Peptide Vaccine against Influenza A Viruses Developed in HLA-A*2402 Human Immunity Model

(2011) Toru Ichihashi et al.   PLoS One

Meta-Analysis of the Immunogenicity and Tolerability of Pandemic Influenza A 2009 (H1N1) Vaccines

(2011) Lamberto Manzoli et al.   PLoS One

Sublingual Immunization with M2-Based Vaccine Induces Broad Protective Immunity against Influenza

(2011) Byoung-Shik Shim et al.   PLoS One

Immunogenicity and safety of inactivated influenza vaccines in primed populations: A systematic literature review and meta-analysis

(2011) W.E.P. Beyer et al.   VACCINE

Evaluation of a virosomal H5N1 vaccine formulated with Matrix M™ adjuvant in a phase I clinical trial

(2011) Rebecca J. Cox et al.   VACCINE

Evaluation of the safety, reactogenicity and immunogenicity of FluBlok® trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy adults 50–64 years of age☆

(2011) R. Baxter et al.   VACCINE

Prospects for controlling future pandemics of influenza

(2011) James S. Robertson et al.   VIRUS RESEARCH

Influenza virus vaccines: lessons from the 2009 H1N1 pandemic

(2011) Andrew J Broadbent et al.   Current Opinion in Virology

A CTL-based liposomal vaccine capable of inducing protection against heterosubtypic influenza viruses in HLA-A*0201 transgenic mice

(2010) Masanori Matsui et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

PCPP-Formulated H5N1 Influenza Vaccine Displays Improved Stability and Dose-Sparing Effect in Lethal Challenge Studies

(2010) Alexander K. Andrianov et al.   JOURNAL OF PHARMACEUTICAL SCIENCES

A Single Immunization with CoVaccine HT-Adjuvanted H5N1 Influenza Virus Vaccine Induces Protective Cellular and Humoral Immune Responses in Ferrets

(2010) R. Bodewes et al.   JOURNAL OF VIROLOGY

Intranasal Immunization with Influenza VLPs Incorporating Membrane-Anchored Flagellin Induces Strong Heterosubtypic Protection

(2010) Bao-Zhong Wang et al.   PLoS One

Vaccination with a synthetic peptide from the influenza virus hemagglutinin provides protection against distinct viral subtypes

(2010) T. T. Wang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Safety and immunogenicity of a recombinant hemagglutinin influenza–flagellin fusion vaccine (VAX125) in healthy young adults

(2010) John J. Treanor et al.   VACCINE

Trivalent MDCK cell culture-derived influenza vaccine Optaflu®(Novartis Vaccines)

(2009) Alexander Doroshenko et al.   Expert Review of Vaccines

Animal models for the preclinical evaluation of candidate influenza vaccines

(2009) Rogier Bodewes et al.   Expert Review of Vaccines

Differential susceptibility of different cell lines to swine-origin influenza A H1N1, seasonal human influenza A H1N1, and avian influenza A H5N1 viruses

(2009) I.W.S. Li et al.   JOURNAL OF CLINICAL VIROLOGY

Evaluation of Vaccines for H5N1 Influenza Virus in Ferrets Reveals the Potential for Protective Single-Shot Immunization

(2009) D. Middleton et al.   JOURNAL OF VIROLOGY

Flu Myths: Dispelling the Myths Associated With Live Attenuated Influenza Vaccine

(2009) Pritish K. Tosh et al.   MAYO CLINIC PROCEEDINGS

Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus

(2009) E. M. Sorrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antigenic and Genetic Characteristics of Swine-Origin 2009 A(H1N1) Influenza Viruses Circulating in Humans

(2009) R. J. Garten et al.   SCIENCE

Evaluation of the safety, reactogenicity and immunogenicity of FluBlok® trivalent recombinant baculovirus-expressed hemagglutinin influenza vaccine administered intramuscularly to healthy children aged 6–59 months

(2009) James C. King et al.   VACCINE

M2e-based universal influenza A vaccine

(2009) Walter Fiers et al.   VACCINE

Correlation of Cellular Immune Responses with Protection against Culture-Confirmed Influenza Virus in Young Children

(2008) B. D. Forrest et al.   Clinical and Vaccine Immunology

Superior induction of anti-tumor CTL immunity by extended peptide vaccines involves prolonged, DC-focused antigen presentation

(2008) Martijn S. Bijker et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Animal models in influenza vaccine testing

(2008) Jan Willem van der Laan et al.   Expert Review of Vaccines

Using Surveillance to Evaluate Influenza Vaccine Effectiveness

(2008) Lisa A. Jackson   JOURNAL OF INFECTIOUS DISEASES

Influenza vaccination and risk of community-acquired pneumonia

(2008) Carel Thijs et al.   LANCET

Prevention and Treatment of Seasonal Influenza

(2008) W. Paul Glezen   NEW ENGLAND JOURNAL OF MEDICINE

Development of Stable Influenza Vaccine Powder Formulations: Challenges and Possibilities

(2008) J-P. Amorij et al.   PHARMACEUTICAL RESEARCH

Cross-Protection against Lethal H5N1 Challenge in Ferrets with an Adjuvanted Pandemic Influenza Vaccine

(2008) Benoît Baras et al.   PLoS One

Reduced reaction frequencies with repeated inactivated or live-attenuated influenza vaccination

(2008) Suzanne E. Ohmit et al.   VACCINE