Vaccination With Viral Vectors Expressing Chimeric Hemagglutinin, NP and M1 Antigens Protects Ferrets Against Influenza Virus Challenge

Cross-reactive antibodies binding to H4 hemagglutinin protect against a lethal H4N6 influenza virus challenge in the mouse model

(2019) Fatima Amanat et al.   Emerging Microbes & Infections

Novel correlates of protection against pandemic H1N1 influenza A virus infection

(2019) Sophia Ng et al.   NATURE MEDICINE

Sequential Immunization With Live-Attenuated Chimeric Hemagglutinin-Based Vaccines Confers Heterosubtypic Immunity Against Influenza A Viruses in a Preclinical Ferret Model

(2019) Wen-Chun Liu et al.   Frontiers in Immunology

Vaccination with viral vectors expressing NP, M1 and chimeric hemagglutinin induces broad protection against influenza virus challenge in mice

(2019) Guha Asthagiri Arunkumar et al.   VACCINE

Influenza Infection in Humans Induces Broadly Cross-Reactive and Protective Neuraminidase-Reactive Antibodies

(2018) Yao-Qing Chen et al.   CELL

Overcoming Barriers in the Path to a Universal Influenza Virus Vaccine

(2018) Lynda Coughlan et al.   Cell Host & Microbe

Moving Forward: Recent Developments for the Ferret Biomedical Research Model

(2018) Randy A. Albrecht et al.   mBio

Heterologous Two-Dose Vaccination with Simian Adenovirus and Poxvirus Vectors Elicits Long-Lasting Cellular Immunity to Influenza Virus A in Healthy Adults

(2018) L. Coughlan et al.   EBioMedicine

The influenza virus hemagglutinin head evolves faster than the stalk domain

(2018) Ericka Kirkpatrick et al.   Scientific Reports

Universal influenza virus vaccines that target the conserved hemagglutinin stalk and conserved sites in the head domain

(2018) Florian Krammer et al.   JOURNAL OF INFECTIOUS DISEASES

A universal influenza virus vaccine candidate confers protection against pandemic H1N1 infection in preclinical ferret studies

(2017) Raffael Nachbagauer et al.   npj Vaccines

Influenza A Viruses Expressing Intra- or Intergroup Chimeric Hemagglutinins

(2016) Chi-Jene Chen et al.   JOURNAL OF VIROLOGY

Flow Cytometric and Cytokine ELISpot Approaches To Characterize the Cell-Mediated Immune Response in Ferrets following Influenza Virus Infection

(2016) Anthony DiPiazza et al.   JOURNAL OF VIROLOGY

Heterosubtypic T-Cell Immunity to Influenza in Humans: Challenges for Universal T-Cell Influenza Vaccines

(2016) Saranya Sridhar   Frontiers in Immunology

A chimeric haemagglutinin-based influenza split virion vaccine adjuvanted with AS03 induces protective stalk-reactive antibodies in mice

(2016) Raffael Nachbagauer et al.   npj Vaccines

Natural T Cell–mediated Protection against Seasonal and Pandemic Influenza. Results of the Flu Watch Cohort Study

(2015) Andrew C. Hayward et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Hemagglutinin Stalk Immunity Reduces Influenza Virus Replication and Transmission in Ferrets

(2015) Raffael Nachbagauer et al.   JOURNAL OF VIROLOGY

Advances in the development of influenza virus vaccines

(2015) Florian Krammer et al.   NATURE REVIEWS DRUG DISCOVERY

Assessment of Influenza Virus Hemagglutinin Stalk-Based Immunity in Ferrets

(2014) F. Krammer et al.   JOURNAL OF VIROLOGY

H3 Stalk-Based Chimeric Hemagglutinin Influenza Virus Constructs Protect Mice from H7N9 Challenge

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

H3N2 Influenza Virus Infection Induces Broadly Reactive Hemagglutinin Stalk Antibodies in Humans and Mice

(2013) I. Margine et al.   JOURNAL OF VIROLOGY

Human Cytotoxic T Lymphocytes Directed to Seasonal Influenza A Viruses Cross-React with the Newly Emerging H7N9 Virus

(2013) C. E. van de Sandt et al.   JOURNAL OF VIROLOGY

Hemagglutinin Stalk-Based Universal Vaccine Constructs Protect against Group 2 Influenza A Viruses

(2013) I. Margine et al.   JOURNAL OF VIROLOGY

Chimeric Hemagglutinin Influenza Virus Vaccine Constructs Elicit Broadly Protective Stalk-Specific Antibodies

(2013) F. Krammer et al.   JOURNAL OF VIROLOGY

Clinical Assessment of a Novel Recombinant Simian Adenovirus ChAdOx1 as a Vectored Vaccine Expressing Conserved Influenza A Antigens

(2013) Richard D Antrobus et al.   MOLECULAR THERAPY

Cellular immune correlates of protection against symptomatic pandemic influenza

(2013) Saranya Sridhar et al.   NATURE MEDICINE

Immunity Against Heterosubtypic Influenza Virus Induced By Adenovirus And MVA Expressing Nucleoprotein And Matrix Protein-1

(2013) Teresa Lambe et al.   Scientific Reports

Expression of Functional Recombinant Hemagglutinin and Neuraminidase Proteins from the Novel H7N9 Influenza Virus Using the Baculovirus Expression System

(2013) Irina Margine et al.   Jove-Journal of Visualized Experiments

Preliminary Assessment of the Efficacy of a T-Cell–Based Influenza Vaccine, MVA-NP+M1, in Humans

(2012) Patrick J. Lillie et al.   CLINICAL INFECTIOUS DISEASES

Seasonal Trivalent Inactivated Influenza Vaccine Does Not Protect against Newly Emerging Variants of Influenza A (H3N2v) Virus in Ferrets

(2012) K. V. Houser et al.   JOURNAL OF VIROLOGY

A Pan-H1 Anti-Hemagglutinin Monoclonal Antibody with Potent Broad-Spectrum Efficacy In Vivo

(2012) G. S. Tan et al.   JOURNAL OF VIROLOGY

Expression and Cellular Immunogenicity of a Transgenic Antigen Driven by Endogenous Poxviral Early Promoters at Their Authentic Loci in MVA

(2012) Toritse Orubu et al.   PLoS One

A Novel Chimpanzee Adenovirus Vector with Low Human Seroprevalence: Improved Systems for Vector Derivation and Comparative Immunogenicity

(2012) Matthew D. J. Dicks et al.   PLoS One

A Carboxy-Terminal Trimerization Domain Stabilizes Conformational Epitopes on the Stalk Domain of Soluble Recombinant Hemagglutinin Substrates

(2012) Florian Krammer et al.   PLoS One

Hemagglutinin stalk antibodies elicited by the 2009 pandemic influenza virus as a mechanism for the extinction of seasonal H1N1 viruses

(2012) N. Pica et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Surface glycoproteins of influenza A H3N2 virus modulate virus replication in the respiratory tract of ferrets

(2012) Xing Cheng et al.   VIROLOGY

Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

(2011) Jens Wrammert et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Contributions of Antinucleoprotein IgG to Heterosubtypic Immunity against Influenza Virus

(2011) Mark W. LaMere et al.   JOURNAL OF IMMUNOLOGY

Regulation of Antinucleoprotein IgG by Systemic Vaccination and Its Effect on Influenza Virus Clearance

(2011) M. W. LaMere et al.   JOURNAL OF VIROLOGY

Potent CD8+ T-Cell Immunogenicity in Humans of a Novel Heterosubtypic Influenza A Vaccine, MVA-NP+M1

(2010) T. K. Berthoud et al.   CLINICAL INFECTIOUS DISEASES

A Trivalent Virus-Like Particle Vaccine Elicits Protective Immune Responses against Seasonal Influenza Strains in Mice and Ferrets

(2009) Ted M. Ross et al.   PLoS One

Modified H5 promoter improves stability of insert genes while maintaining immunogenicity during extended passage of genetically engineered MVA vaccines

(2009) Zhongde Wang et al.   VACCINE

The Pathology of Influenza Virus Infections

(2008) Jeffery K. Taubenberger et al.   Annual Review of Pathology-Mechanisms of Disease

Memory T cells established by seasonal human influenza A infection cross-react with avian influenza A (H5N1) in healthy individuals

(2008) Laurel Yong-Hwa Lee et al.   JOURNAL OF CLINICAL INVESTIGATION