Animal Models for Influenza Virus Pathogenesis and Transmission

Interferon-Induced Expression of MxA in the Respiratory Tract of Rhesus Macaques Is Suppressed by Influenza Virus Replication

(2014) T. D. Carroll et al.   JOURNAL OF IMMUNOLOGY

Epidemic viral pneumonia

(2010) Stephen E Lapinsky   CURRENT OPINION IN INFECTIOUS DISEASES

Mutations in the NS1 C-terminal tail do not enhance replication or virulence of the 2009 pandemic H1N1 influenza A virus

(2010) B. G. Hale et al.   JOURNAL OF GENERAL VIROLOGY

Household Transmission of 2009 Influenza A (H1N1) Virus after a School‐Based Outbreak in New York City, April–May 2009

(2010) Anne Marie France et al.   JOURNAL OF INFECTIOUS DISEASES

Effect of the Neuraminidase Mutation H274Y Conferring Resistance to Oseltamivir on the Replicative Capacity and Virulence of Old and Recent Human Influenza A(H1N1) Viruses

(2010) Mariana Baz et al.   JOURNAL OF INFECTIOUS DISEASES

Cross-Reactive Neutralizing Antibodies Directed against Pandemic H1N1 2009 Virus Are Protective in a Highly Sensitive DBA/2 Mouse Influenza Model

(2010) A. C. M. Boon et al.   JOURNAL OF VIROLOGY

PB1-F2 Expression by the 2009 Pandemic H1N1 Influenza Virus Has Minimal Impact on Virulence in Animal Models

(2010) R. Hai et al.   JOURNAL OF VIROLOGY

Alternative Live-Attenuated Influenza Vaccines Based on Modifications in the Polymerase Genes Protect against Epidemic and Pandemic Flu

(2010) A. Solorzano et al.   JOURNAL OF VIROLOGY

Pathogenesis of Pandemic Influenza A (H1N1) and Triple-Reassortant Swine Influenza A (H1) Viruses in Mice

(2010) J. A. Belser et al.   JOURNAL OF VIROLOGY

Gene expression changes in the host response between resistant and susceptible inbred mouse strains after influenza A infection

(2010) Rudi Alberts et al.   MICROBES AND INFECTION

Avian influenza virus isolates from wild birds replicate and cause disease in a mouse model of infection

(2010) Elizabeth A. Driskell et al.   VIROLOGY

Protection of Mice against Lethal Challenge with 2009 H1N1 Influenza A Virus by 1918-Like and Classical Swine H1N1 Based Vaccines

(2010) Balaji Manicassamy et al.   PLoS Pathogens

Susceptibility of Highly Pathogenic H5N1 Influenza Viruses to the Neuraminidase Inhibitor Oseltamivir Differs In Vitro and in a Mouse Model

(2009) E. A. Govorkova et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

(2009) D. F. Smee et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The olfactory nerve has a role in the body temperature and brain cytokine responses to influenza virus

(2009) Victor H. Leyva-Grado et al.   BRAIN BEHAVIOR AND IMMUNITY

Histopathology and growth kinetics of influenza viruses (H1N1 and H3N2) in the upper and lower airways of guinea pigs

(2009) X. Tang et al.   JOURNAL OF GENERAL VIROLOGY

Transmission of Influenza Virus via Aerosols and Fomites in the Guinea Pig Model

(2009) Samira Mubareka et al.   JOURNAL OF INFECTIOUS DISEASES

Exhalation of respiratory viruses by breathing, coughing, and talking

(2009) Sacha Stelzer-Braid et al.   JOURNAL OF MEDICAL VIROLOGY

Transmission of Pandemic H1N1 Influenza Virus and Impact of Prior Exposure to Seasonal Strains or Interferon Treatment

(2009) J. Steel et al.   JOURNAL OF VIROLOGY

Pathogenesis of 1918 Pandemic and H5N1 Influenza Virus Infections in a Guinea Pig Model: Antiviral Potential of Exogenous Alpha Interferon To Reduce Virus Shedding

(2009) N. Van Hoeven et al.   JOURNAL OF VIROLOGY

Reassortment between Avian H5N1 and Human H3N2 Influenza Viruses in Ferrets: a Public Health Risk Assessment

(2009) S. Jackson et al.   JOURNAL OF VIROLOGY

Electroporation of Synthetic DNA Antigens Offers Protection in Nonhuman Primates Challenged with Highly Pathogenic Avian Influenza Virus

(2009) D. J. Laddy et al.   JOURNAL OF VIROLOGY

Host Genetic Variation Affects Resistance to Infection with a Highly Pathogenic H5N1 Influenza A Virus in Mice

(2009) A. C. M. Boon et al.   JOURNAL OF VIROLOGY

Blocking Interhost Transmission of Influenza Virus by Vaccination in the Guinea Pig Model

(2009) A. C. Lowen et al.   JOURNAL OF VIROLOGY

In vitro and in vivo characterization of new swine-origin H1N1 influenza viruses

(2009) Yasushi Itoh et al.   NATURE

Household Transmission of 2009 Pandemic Influenza A (H1N1) Virus in the United States

(2009) Simon Cauchemez et al.   NEW ENGLAND JOURNAL OF MEDICINE

Host Genetic Background Strongly Influences the Response to Influenza A Virus Infections

(2009) Barkha Srivastava et al.   PLoS One

T-705 (favipiravir) activity against lethal H5N1 influenza A viruses

(2009) M. Kiso et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal molecular constraints for respiratory droplet transmission of an avian-human H9N2 influenza A virus

(2009) E. M. Sorrell et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Highly pathogenic H5N1 influenza virus can enter the central nervous system and induce neuroinflammation and neurodegeneration

(2009) H. Jang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Influenza B Virus Causes Milder Pathogenesis and Weaker Inflammatory Responses in Ferrets Than Influenza A Virus

(2009) Yun Hee Kim et al.   VIRAL IMMUNOLOGY

Identification of Amino Acids in HA and PB2 Critical for the Transmission of H5N1 Avian Influenza Viruses in a Mammalian Host

(2009) Yuwei Gao et al.   PLoS Pathogens

Immunogenicity and Protective Efficacy of a Live Attenuated H5N1 Vaccine in Nonhuman Primates

(2009) Shufang Fan et al.   PLoS Pathogens

Lethal Influenza Virus Infection in Macaques Is Associated with Early Dysregulation of Inflammatory Related Genes

(2009) Cristian Cillóniz et al.   PLoS Pathogens

Transmission of Influenza Virus in a Mammalian Host Is Increased by PB2 Amino Acids 627K or 627E/701N

(2009) John Steel et al.   PLoS Pathogens

Time Lines of Infection and Disease in Human Influenza: A Review of Volunteer Challenge Studies

(2008) Fabrice Carrat et al.   AMERICAN JOURNAL OF EPIDEMIOLOGY

Influenza A Virus Inhibits Alveolar Fluid Clearance in BALB/c Mice

(2008) Kendra E. Wolk et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Oseltamivir-Ribavirin Combination Therapy for Highly Pathogenic H5N1 Influenza Virus Infection in Mice

(2008) N. A. Ilyushina et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Evaluation of intravenous zanamivir against experimental influenza A (H5N1) virus infection in cynomolgus macaques

(2008) K STITTELAAR et al.   ANTIVIRAL RESEARCH

Intramuscularly administered neuraminidase inhibitor peramivir is effective against lethal H5N1 influenza virus in mice

(2008) D BOLTZ et al.   ANTIVIRAL RESEARCH

Oseltamivir Prophylactic Regimens Prevent H5N1 Influenza Morbidity and Mortality in a Ferret Model

(2008) David A. Boltz et al.   JOURNAL OF INFECTIOUS DISEASES

Influenza B Virus NS1-Truncated Mutants: Live-Attenuated Vaccine Approach

(2008) R. Hai et al.   JOURNAL OF VIROLOGY

Monoclonal Antibodies against the Fusion Peptide of Hemagglutinin Protect Mice from Lethal Influenza A Virus H5N1 Infection

(2008) N. Prabhu et al.   JOURNAL OF VIROLOGY

High Temperature (30 C) Blocks Aerosol but Not Contact Transmission of Influenza Virus

(2008) A. C. Lowen et al.   JOURNAL OF VIROLOGY

Gene Expression Analysis of Host Innate Immune Responses during Lethal H5N1 Infection in Ferrets

(2008) C. M. Cameron et al.   JOURNAL OF VIROLOGY

Oseltamivir-Resistant Influenza A Viruses Are Transmitted Efficiently among Guinea Pigs by Direct Contact but Not by Aerosol

(2008) N. M. Bouvier et al.   JOURNAL OF VIROLOGY

Influenza Virus in Human Exhaled Breath: An Observational Study

(2008) Patricia Fabian et al.   PLoS One

Replication and Transmission of H9N2 Influenza Viruses in Ferrets: Evaluation of Pandemic Potential

(2008) Hongquan Wan et al.   PLoS One

Contemporary North American influenza H7 viruses possess human receptor specificity: Implications for virus transmissibility

(2008) J. A. Belser et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A bivalent influenza VLP vaccine confers complete inhibition of virus replication in lungs

(2008) Fu Shi Quan et al.   VACCINE

Bronchointerstitial Pneumonia in Guinea Pigs Following Inoculation with H5N1 High Pathogenicity Avian Influenza Virus

(2008) Y. K. Kwon et al.   VETERINARY PATHOLOGY

Injectable peramivir mitigates disease and promotes survival in ferrets and mice infected with the highly virulent influenza virus, A/Vietnam/1203/04 (H5N1)

(2008) Nadezhda E. Yun et al.   VIROLOGY

Antibody contributes to heterosubtypic protection against influenza A-induced tachypnea in cotton rats

(2008) Timothy M Straight et al.   Virology Journal

H5N1 and 1918 Pandemic Influenza Virus Infection Results in Early and Excessive Infiltration of Macrophages and Neutrophils in the Lungs of Mice

(2008) Lucy A. Perrone et al.   PLoS Pathogens