Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response
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Title
Deubiquitinating enzymes (DUBs): Regulation, homeostasis, and oxidative stress response
Authors
Keywords
DUB, deubiquitination, ubiquitin, enzymatic regulation, oxidative stress, redox signaling, translation
Journal
JOURNAL OF BIOLOGICAL CHEMISTRY
Volume 297, Issue 3, Pages 101077
Publisher
Elsevier BV
Online
2021-08-12
DOI
10.1016/j.jbc.2021.101077
References
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Note: Only part of the references are listed.- In‐depth and 3‐dimensional exploration of the budding yeast phosphoproteome
- (2021) Michael C Lanz et al. EMBO REPORTS
- Molecular Mechanisms of DUBs Regulation in Signaling and Disease
- (2021) Ying Li et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Deubiquitylating enzymes in neuronal health and disease
- (2021) Fatima Amer-Sarsour et al. Cell Death & Disease
- OTUB1 stabilizes mismatch repair protein MSH2 by blocking ubiquitination
- (2021) Qiong Wu et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The ubiquitination-deubiquitination cycle on the ribosomal protein eS7A is crucial for efficient translation
- (2021) Yuka Takehara et al. iScience
- Comparative profiling of stress granule clearance reveals differential contributions of the ubiquitin system
- (2021) Nazife Tolay et al. Life Science Alliance
- Pharmacological inhibition of USP30 activates tissue‐specific mitophagy
- (2021) Hongke Luo et al. Acta Physiologica
- Ubiquitin specific peptidase 32 acts as an oncogene in epithelial ovarian cancer by deubiquitylating farnesyl-diphosphate farnesyltransferase 1
- (2021) Aya Nakae et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Ubiquitylation of lipopolysaccharide by RNF213 during bacterial infection
- (2021) Elsje G. Otten et al. NATURE
- Mechanisms and consequences of protein cysteine oxidation: the role of the initial short-lived intermediates
- (2020) Lucia Turell et al. Essays in Biochemistry
- USP8 Mutations and Cell Cycle Regulation in Corticotroph Adenomas
- (2020) Clarissa Silva Martins et al. HORMONE AND METABOLIC RESEARCH
- Expanding Role of Ubiquitin in Translational Control
- (2020) Shannon E. Dougherty et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- Phase 1 study of the protein deubiquitinase inhibitor VLX1570 in patients with relapsed and/or refractory multiple myeloma
- (2020) Eric K. Rowinsky et al. INVESTIGATIONAL NEW DRUGS
- The G3BP1-Family-USP10 Deubiquitinase Complex Rescues Ubiquitinated 40S Subunits of Ribosomes Stalled in Translation from Lysosomal Degradation
- (2020) Cindy Meyer et al. MOLECULAR CELL
- Rapid and deep-scale ubiquitylation profiling for biology and translational research
- (2020) Namrata D. Udeshi et al. Nature Communications
- Distinct Regulatory Ribosomal Ubiquitylation events are reversible and hierarchically organized
- (2020) Danielle M Garshott et al. eLife
- Linear Ubiquitin Chains: Cellular Functions and Strategies for Detection and Quantification
- (2020) Gunnar Dittmar et al. Frontiers in Chemistry
- Antagonistic activities of CDC14B and CDK1 on USP9X regulate WT1-dependent mitotic transcription and survival
- (2020) Michael Dietachmayr et al. Nature Communications
- Regulation of Deubiquitinating Enzymes by Post-Translational Modifications
- (2020) Tanuza Das et al. INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES
- A novel mechanism for the retention of Golgi membrane proteins mediated by the Bre5p/Ubp3p de-ubiquitinase complex
- (2020) Peng Wang et al. MOLECULAR BIOLOGY OF THE CELL
- Acetylation-Dependent Deubiquitinase OTUD3 Controls MAVS Activation in Innate Antiviral Immunity
- (2020) Zhengkui Zhang et al. MOLECULAR CELL
- Deubiquitinating Enzymes in Parkinson’s Disease
- (2020) Joy Chakraborty et al. Frontiers in Physiology
- The deubiquitinase JOSD2 is a positive regulator of glucose metabolism
- (2020) Lyudmila Krassikova et al. CELL DEATH AND DIFFERENTIATION
- OTUD5 promotes innate antiviral and antitumor immunity through deubiquitinating and stabilizing STING
- (2020) Yunyun Guo et al. Cellular & Molecular Immunology
- Elevated post-ischemic ubiquitination results from suppression of deubiquitinase activity and not proteasome inhibition
- (2020) Timo Kahles et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Structural impact of K63 ubiquitin on yeast translocating ribosomes under oxidative stress
- (2020) Ye Zhou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- A20 promotes melanoma progression via the activation of Akt pathway
- (2020) Jinyuan Ma et al. Cell Death & Disease
- The structure and function of deubiquitinases: lessons from budding yeast
- (2020) Harsha Garadi Suresh et al. Open Biology
- Oxidative Stress in Amyotrophic Lateral Sclerosis: Pathophysiology and Opportunities for Pharmacological Intervention
- (2020) Teresa Cunha-Oliveira et al. Oxidative Medicine and Cellular Longevity
- FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
- (2019) Anthony Arceci et al. Cell Reports
- USP32 regulates late endosomal transport and recycling through deubiquitylation of Rab7
- (2019) Aysegul Sapmaz et al. Nature Communications
- Differential Oligomerization of the Deubiquitinases USP25 and USP28 Regulates Their Activities
- (2019) Florian Sauer et al. MOLECULAR CELL
- Distinct USP25 and USP28 Oligomerization States Regulate Deubiquitinating Activity
- (2019) Malte Gersch et al. MOLECULAR CELL
- Deubiquitinating enzyme USP30 maintains basal peroxisome abundance by regulating pexophagy
- (2019) Victoria Riccio et al. JOURNAL OF CELL BIOLOGY
- USP7: Structure, substrate specificity, and inhibition
- (2019) Alexandra Pozhidaeva et al. DNA REPAIR
- The deubiquitinase Otub1 controls the activation of CD8+ T cells and NK cells by regulating IL-15-mediated priming
- (2019) Xiaofei Zhou et al. NATURE IMMUNOLOGY
- Polyubiquitin chains linked by lysine residue 48 (K48) selectively target oxidized proteins in vivo
- (2019) Sandhya Manohar et al. ANTIOXIDANTS & REDOX SIGNALING
- DUBbing Down Translation: The Functional Interaction of Deubiquitinases with the Translational Machinery
- (2019) Bandish B. Kapadia et al. MOLECULAR CANCER THERAPEUTICS
- Cellular functions and molecular mechanisms of non-lysine ubiquitination
- (2019) Amie J. McClellan et al. Open Biology
- Advances in Discovering Deubiquitinating Enzyme (DUB) Inhibitors
- (2019) Nathan J. Schauer et al. JOURNAL OF MEDICINAL CHEMISTRY
- USP14 regulates DNA damage repair by targeting RNF168-dependent ubiquitination
- (2018) Arishya Sharma et al. Autophagy
- Role of mitochondrial ROS in the brain: from physiology to neurodegeneration
- (2018) Plamena R. Angelova et al. FEBS LETTERS
- Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability
- (2018) Dominika Kwasna et al. MOLECULAR CELL
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- The Good, the Bad, and the Ugly of ROS: New Insights on Aging and Aging-Related Diseases from Eukaryotic and Prokaryotic Model Organisms
- (2018) Ana L. Santos et al. Oxidative Medicine and Cellular Longevity
- MINDY1 is a Downstream Target of the Polyamines and Promotes Embryonic Stem Cell Self-Renewal
- (2018) Christina James et al. STEM CELLS
- Fatty Acid Synthase induced S6Kinase facilitates USP11-eIF4B complex formation for sustained oncogenic translation in DLBCL
- (2018) Bandish Kapadia et al. Nature Communications
- UbiSite approach for comprehensive mapping of lysine and N-terminal ubiquitination sites
- (2018) Vyacheslav Akimov et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Clinical Significance of Ubiquitin Specific Protease 7 (USP7) in Predicting Prognosis of Hepatocellular Carcinoma and its Functional Mechanisms
- (2018) Xujing Wang et al. MEDICAL SCIENCE MONITOR
- Oxidative stress, aging, and diseases
- (2018) Ilaria Liguori et al. Clinical Interventions in Aging
- A Comprehensive Atlas of E3 Ubiquitin Ligase Mutations in Neurological Disorders
- (2018) Arlene J. George et al. Frontiers in Genetics
- Regulation of Gli2 stability by deubiquitinase OTUB2
- (2018) Xin-Yan Li et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mutations of deubiquitinase OTUD1 are associated with autoimmune disorders
- (2018) Dan Lu et al. JOURNAL OF AUTOIMMUNITY
- Deubiquitinase Usp12 functions noncatalytically to induce autophagy and confer neuroprotection in models of Huntington’s disease
- (2018) Rebecca Aron et al. Nature Communications
- A quaternary tetramer assembly inhibits the deubiquitinating activity of USP25
- (2018) Bing Liu et al. Nature Communications
- Integration of cellular ubiquitin and membrane traffic systems: focus on deubiquitylases
- (2017) Michael J. Clague et al. FEBS Journal
- Meddling with Fate: The Proteasomal Deubiquitinating Enzymes
- (2017) Stefanie A.H. de Poot et al. JOURNAL OF MOLECULAR BIOLOGY
- An AAA Motor-Driven Mechanical Switch in Rpn11 Controls Deubiquitination at the 26S Proteasome
- (2017) Evan J. Worden et al. MOLECULAR CELL
- A20 promotes metastasis of aggressive basal-like breast cancers through multi-monoubiquitylation of Snail1
- (2017) Ji-Hyung Lee et al. NATURE CELL BIOLOGY
- Deubiquitylating enzymes and drug discovery: emerging opportunities
- (2017) Jeanine A. Harrigan et al. NATURE REVIEWS DRUG DISCOVERY
- Mechanism and regulation of the Lys6-selective deubiquitinase USP30
- (2017) Malte Gersch et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- USP9X controls translation efficiency via deubiquitination of eukaryotic translation initiation factor 4A1
- (2017) Zengxia Li et al. NUCLEIC ACIDS RESEARCH
- Relationships between Stress Granules, Oxidative Stress, and Neurodegenerative Diseases
- (2017) Lihua Chen et al. Oxidative Medicine and Cellular Longevity
- Ubiquitination and the Regulation of Membrane Proteins
- (2017) Natalie Foot et al. PHYSIOLOGICAL REVIEWS
- BAP1 inhibits the ER stress gene regulatory network and modulates metabolic stress response
- (2017) Fangyan Dai et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- USP9X regulates centrosome duplication and promotes breast carcinogenesis
- (2017) Xin Li et al. Nature Communications
- Mechanism and regulation of the Lys6-selective deubiquitinase USP30
- (2017) Malte Gersch et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- CYLD Deubiquitinase Negatively Regulates High Glucose-Induced NF-κB Inflammatory Signaling in Mesangial Cells
- (2017) Yanhui Li et al. Biomed Research International
- The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
- (2016) Rune Busk Damgaard et al. CELL
- Substrate specificity of the ubiquitin and Ubl proteases
- (2016) Judith A Ronau et al. CELL RESEARCH
- E2 enzymes: more than just middle men
- (2016) Mikaela D Stewart et al. CELL RESEARCH
- Ubiquitin modifications
- (2016) Kirby N Swatek et al. CELL RESEARCH
- The life cycle of the 26S proteasome: from birth, through regulation and function and onto its death
- (2016) Ido Livneh et al. CELL RESEARCH
- USP9X Controls EGFR Fate by Deubiquitinating the Endocytic Adaptor Eps15
- (2016) Michol Giovanna Savio et al. CURRENT BIOLOGY
- Deubiquitination and the regulation of stress granule assembly
- (2016) R. Nostramo et al. CURRENT GENETICS
- USP12 regulates cell cycle progression by involving c-Myc, cyclin D2 and BMI-1
- (2016) Li-Juan Tang et al. GENE
- Ubiquitin-Specific Protease 4 Antagonizes Osteoblast Differentiation Through Dishevelled
- (2016) Fangfang Zhou et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Length Matters: MINDY Is a New Deubiquitinase Family that Preferentially Cleaves Long Polyubiquitin Chains
- (2016) Till Maurer et al. MOLECULAR CELL
- Allosteric Activation of Ubiquitin-Specific Proteases by β-Propeller Proteins UAF1 and WDR20
- (2016) Heng Li et al. MOLECULAR CELL
- MINDY-1 Is a Member of an Evolutionarily Conserved and Structurally Distinct New Family of Deubiquitinating Enzymes
- (2016) Syed Arif Abdul Rehman et al. MOLECULAR CELL
- USP37 deubiquitinates Cdt1 and contributes to regulate DNA replication
- (2016) Santiago Hernández-Pérez et al. Molecular Oncology
- The increasing complexity of the ubiquitin code
- (2016) Richard Yau et al. NATURE CELL BIOLOGY
- ROS and ROS-Mediated Cellular Signaling
- (2016) Jixiang Zhang et al. Oxidative Medicine and Cellular Longevity
- Deubiquitinase Usp8 regulates α-synuclein clearance and modifies its toxicity in Lewy body disease
- (2016) Zoi Alexopoulou et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Principles and Properties of Stress Granules
- (2016) David S.W. Protter et al. TRENDS IN CELL BIOLOGY
- Deubiquitinase activity is required for the proteasomal degradation of misfolded cytosolic proteins upon heat-stress
- (2016) Nancy N. Fang et al. Nature Communications
- USP19 deubiquitinates HDAC1/2 to regulate DNA damage repair and control chromosomal stability
- (2016) Min Wu et al. Oncotarget
- Orderly progression through S-phase requires dynamic ubiquitylation and deubiquitylation of PCNA
- (2016) Vanesa Álvarez et al. Scientific Reports
- The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics
- (2016) Mingjing He et al. Cell and Bioscience
- Deubiquitinase OTUD5 mediates the sequential activation of PDCD5 and p53 in response to genotoxic stress
- (2015) Soo-Yeon Park et al. CANCER LETTERS
- Synthesis and Evaluation of Derivatives of the Proteasome Deubiquitinase Inhibitor b-AP15
- (2015) Xin Wang et al. Chemical Biology & Drug Design
- The Deubiquitinase USP37 Regulates Chromosome Cohesion and Mitotic Progression
- (2015) Christina Yeh et al. CURRENT BIOLOGY
- USP30 deubiquitylates mitochondrial Parkin substrates and restricts apoptotic cell death
- (2015) J.-R. Liang et al. EMBO REPORTS
- Deubiquitinases and the new therapeutic opportunities offered to cancer
- (2015) R. Pfoh et al. ENDOCRINE-RELATED CANCER
- Biological chemistry and functionality of protein sulfenic acids and related thiol modifications
- (2015) Nelmi O. Devarie-Baez et al. FREE RADICAL RESEARCH
- The deubiquitinating enzyme complex BRISC is required for proper mitotic spindle assembly in mammalian cells
- (2015) Kaowen Yan et al. JOURNAL OF CELL BIOLOGY
- Cutting Edge: Ubiquitin-Specific Protease 4 Promotes Th17 Cell Function under Inflammation by Deubiquitinating and Stabilizing RORγt
- (2015) Jing Yang et al. JOURNAL OF IMMUNOLOGY
- Role of Deubiquitinating Enzymes in DNA Repair
- (2015) Younghoon Kee et al. MOLECULAR AND CELLULAR BIOLOGY
- Overexpression of ubiquitin carboxyl terminal hydrolase-L1 enhances multidrug resistance and invasion/metastasis in breast cancer by activating the MAPK/Erk signaling pathway
- (2015) Wenjuan Wang et al. MOLECULAR CARCINOGENESIS
- USP7 Acts as a Molecular Rheostat to Promote WASH-Dependent Endosomal Protein Recycling and Is Mutated in a Human Neurodevelopmental Disorder
- (2015) Yi-Heng Hao et al. MOLECULAR CELL
- Structural Basis for the Activation and Inhibition of the UCH37 Deubiquitylase
- (2015) Ryan T. VanderLinden et al. MOLECULAR CELL
- Ubiquitin specific protease 4 positively regulates the WNT/β-catenin signaling in colorectal cancer
- (2015) Sun-Il Yun et al. Molecular Oncology
- USP30 and parkin homeostatically regulate atypical ubiquitin chains on mitochondria
- (2015) Christian N. Cunningham et al. NATURE CELL BIOLOGY
- K63 polyubiquitination is a new modulator of the oxidative stress response
- (2015) Gustavo M Silva et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- BRUCE regulates DNA double-strand break response by promoting USP8 deubiquitination of BRIT1
- (2015) Chunmin Ge et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16to trigger its nuclear localization
- (2015) Lina Herhaus et al. Science Signaling
- Structural Insights into WD-Repeat 48 Activation of Ubiquitin-Specific Protease 46
- (2015) Jianping Yin et al. STRUCTURE
- Layers of DUB regulation
- (2015) Danny D. Sahtoe et al. TRENDS IN BIOCHEMICAL SCIENCES
- K63 polyubiquitination is a new modulator of the oxidative stress response
- (2015) Gustavo M Silva et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krüppel-like factor 5 (KLF5)
- (2015) Fei Ge et al. Oncotarget
- Epigenetic Regulation of Antibody Responses by the Histone H2A Deubiquitinase MYSM1
- (2015) Xiao-Xia Jiang et al. Scientific Reports
- USP7 Is a Suppressor of PCNA Ubiquitination and Oxidative-Stress-Induced Mutagenesis in Human Cells
- (2015) Shu-ichiro Kashiwaba et al. Cell Reports
- Protein Topology Determines Cysteine Oxidation Fate: The Case of Sulfenyl Amide Formation among Protein Families
- (2015) Lucas A. Defelipe et al. PLoS Computational Biology
- Seizures Are Regulated by Ubiquitin-specific Peptidase 9 X-linked (USP9X), a De-Ubiquitinase
- (2015) Lily Paemka et al. PLoS Genetics
- Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system
- (2015) Daichao Xu et al. eLife
- Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16to trigger its nuclear localization
- (2015) Lina Herhaus et al. Science Signaling
- Regulation of the DNA damage response by ubiquitin conjugation
- (2015) Kerstin Brinkmann et al. Frontiers in Genetics
- The de novo synthesis of ubiquitin: identification of deubiquitinases acting on ubiquitin precursors
- (2015) Cláudia P. Grou et al. Scientific Reports
- Insights into the Mechanism of Deubiquitination by JAMM Deubiquitinases from Cocrystal Structures of the Enzyme with the Substrate and Product
- (2014) Rashmi K. Shrestha et al. BIOCHEMISTRY
- Cellular ubiquitin pool dynamics and homeostasis
- (2014) Chul-Woo Park et al. BMB Reports
- Emerging roles of Jab1/CSN5 in DNA damage response, DNA repair, and cancer
- (2014) Yunbao Pan et al. CANCER BIOLOGY & THERAPY
- ROS Function in Redox Signaling and Oxidative Stress
- (2014) Michael Schieber et al. CURRENT BIOLOGY
- BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes
- (2014) Yuki Okino et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice
- (2014) Kiyoko Kato et al. MOLECULAR CELL
- Autodeubiquitination Protects the Tumor Suppressor BAP1 from Cytoplasmic Sequestration Mediated by the Atypical Ubiquitin Ligase UBE2O
- (2014) Nazar Mashtalir et al. MOLECULAR CELL
- The mitochondrial deubiquitinase USP30 opposes parkin-mediated mitophagy
- (2014) Baris Bingol et al. NATURE
- Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity
- (2014) Ryotaro Nishi et al. NATURE CELL BIOLOGY
- Uncovering global SUMOylation signaling networks in a site-specific manner
- (2014) Ivo A Hendriks et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Deubiquitinating activity of CYLD is impaired by SUMOylation in neuroblastoma cells
- (2014) T Kobayashi et al. ONCOGENE
- Ubiquitin-Specific Protease 5 Is Required for the Efficient Repair of DNA Double-Strand Breaks
- (2014) Satoshi Nakajima et al. PLoS One
- Mechanisms for regulating deubiquitinating enzymes
- (2014) Cynthia Wolberger PROTEIN SCIENCE
- Ubiquitin-Dependent Sorting in Endocytosis
- (2014) R. C. Piper et al. Cold Spring Harbor Perspectives in Biology
- Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23
- (2014) Jessica R. Blount et al. Nature Communications
- NF- B, an Active Player in Human Cancers
- (2014) Y. Xia et al. Cancer Immunology Research
- Mechanism of Recruitment and Activation of the Endosome-Associated Deubiquitinase AMSH
- (2013) Christopher W. Davies et al. BIOCHEMISTRY
- Sulfenic acid chemistry, detection and cellular lifetime
- (2013) Vinayak Gupta et al. BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Protein quality control and elimination of protein waste: The role of the ubiquitin–proteasome system
- (2013) Ingo Amm et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- RING-type E3 ligases: Master manipulators of E2 ubiquitin-conjugating enzymes and ubiquitination
- (2013) Meredith B. Metzger et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Regulation of proteolysis by human deubiquitinating enzymes
- (2013) Ziad M. Eletr et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Mesenchymal Differentiation Mediated by NF-κB Promotes Radiation Resistance in Glioblastoma
- (2013) Krishna P.L. Bhat et al. CANCER CELL
- OTU Deubiquitinases Reveal Mechanisms of Linkage Specificity and Enable Ubiquitin Chain Restriction Analysis
- (2013) Tycho E.T. Mevissen et al. CELL
- The Usp8 deubiquitination enzyme is post-translationally modified by tyrosine and serine phosphorylation
- (2013) Inez M.J. Meijer et al. CELLULAR SIGNALLING
- Cysteine Oxidative Posttranslational Modifications
- (2013) Heaseung S. Chung et al. CIRCULATION RESEARCH
- Cezanne Paints Inflammation by Regulating Ubiquitination
- (2013) Jun-ichi Abe et al. CIRCULATION RESEARCH
- Ubiquitin-interacting Motifs Confer Full Catalytic Activity, but Not Ubiquitin Chain Substrate Specificity, to Deubiquitinating Enzyme USP37
- (2013) Hidetaka Tanno et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- JosD1, a Membrane-targeted Deubiquitinating Enzyme, Is Activated by Ubiquitination and Regulates Membrane Dynamics, Cell Motility, and Endocytosis
- (2013) Takahiro Seki et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Stress granules as crucibles of ALS pathogenesis
- (2013) Yun R. Li et al. JOURNAL OF CELL BIOLOGY
- Biochemistry: Oxidation controls the DUB step
- (2013) Michael J. Clague NATURE
- OTUD7B controls non-canonical NF-κB activation through deubiquitination of TRAF3
- (2013) Hongbo Hu et al. NATURE
- Mutations in STAMBP, encoding a deubiquitinating enzyme, cause microcephaly–capillary malformation syndrome
- (2013) Laura M McDonell et al. NATURE GENETICS
- Ubp2 Regulates Rsp5 Ubiquitination Activity In Vivo and In Vitro
- (2013) Mandy H. Y. Lam et al. PLoS One
- Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair
- (2013) H. Yu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin-Specific Protease 25 Regulates TLR4-Dependent Innate Immune Responses Through Deubiquitination of the Adaptor Protein TRAF3
- (2013) B. Zhong et al. Science Signaling
- Regulation of A20 and other OTU deubiquitinases by reversible oxidation
- (2013) Yogesh Kulathu et al. Nature Communications
- Reversible inactivation of deubiquitinases by reactive oxygen species in vitro and in cells
- (2013) Jin-Gu Lee et al. Nature Communications
- Ubiquitin-Binding Proteins: Decoders of Ubiquitin-Mediated Cellular Functions
- (2012) Koraljka Husnjak et al. Annual Review of Biochemistry
- The Ubiquitin Code
- (2012) David Komander et al. Annual Review of Biochemistry
- A Ribosome-Bound Quality Control Complex Triggers Degradation of Nascent Peptides and Signals Translation Stress
- (2012) Onn Brandman et al. CELL
- Regulation of NF-κB signaling by the A20 deubiquitinase
- (2012) Noula Shembade et al. Cellular & Molecular Immunology
- Reactive oxygen species (ROS) homeostasis and redox regulation in cellular signaling
- (2012) Paul D. Ray et al. CELLULAR SIGNALLING
- Oxidative Stress Responses Involve Oxidation of a Conserved Ubiquitin Pathway Enzyme
- (2012) K. S. Doris et al. MOLECULAR AND CELLULAR BIOLOGY
- ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage
- (2012) Svetlana V. Khoronenkova et al. MOLECULAR CELL
- USP4 is regulated by AKT phosphorylation and directly deubiquitylates TGF-β type I receptor
- (2012) Long Zhang et al. NATURE CELL BIOLOGY
- Phosphorylation-dependent activity of the deubiquitinase DUBA
- (2012) Oscar W Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ubiquitin-Specific Protease 25 Functions in Endoplasmic Reticulum-Associated Degradation
- (2012) Jessica R. Blount et al. PLoS One
- Oxidative stress as a cofactor in spinocerebellar ataxia type 2
- (2012) Mariela Guevara-García et al. REDOX REPORT
- Deubiquitinases as a Signaling Target of Oxidative Stress
- (2012) Xiomaris M. Cotto-Rios et al. Cell Reports
- The Role of Deubiquitinating Enzymes in Synaptic Function and Nervous System Diseases
- (2012) Jennifer R. Kowalski et al. NEURAL PLASTICITY
- Molecular Mechanisms of Ubiquitin-Dependent Membrane Traffic
- (2011) James H. Hurley et al. Annual Review of Biophysics
- Ubiquitin-specific protease 4 (USP4) targets TRAF2 and TRAF6 for deubiquitination and inhibits TNFα-induced cancer cell migration
- (2011) Ning Xiao et al. BIOCHEMICAL JOURNAL
- Contribution of Active Site Residues to Substrate Hydrolysis by USP2: Insights into Catalysis by Ubiquitin Specific Proteases
- (2011) Wanfang Zhang et al. BIOCHEMISTRY
- PTMs in Conversation: Activity and Function of Deubiquitinating Enzymes Regulated via Post-Translational Modifications
- (2011) Benedikt M. Kessler et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- Insights into phosphorylation-dependent mechanisms regulating USP1 protein stability during the cell cycle
- (2011) Xiomaris M. Cotto Rios et al. CELL CYCLE
- USP4 targets TAK1 to downregulate TNFα-induced NF-κB activation
- (2011) Y-H Fan et al. CELL DEATH AND DIFFERENTIATION
- USP4 inhibits p53 through deubiquitinating and stabilizing ARF-BP1
- (2011) Xinna Zhang et al. EMBO JOURNAL
- Dissociation by Pelota, Hbs1 and ABCE1 of mammalian vacant 80S ribosomes and stalled elongation complexes
- (2011) Vera P Pisareva et al. EMBO JOURNAL
- Role of ubiquitylation and USP8-dependent deubiquitylation in the endocytosis and lysosomal targeting of plasma membrane KCa3.1
- (2011) Corina M. Balut et al. FASEB JOURNAL
- Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme
- (2011) Tushar K. Maiti et al. FEBS Journal
- Ubiquitin–proteasome pathway and cellular responses to oxidative stress
- (2011) Fu Shang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Structural and Thermodynamic Comparison of the Catalytic Domain of AMSH and AMSH-LP: Nearly Identical Fold but Different Stability
- (2011) Christopher W. Davies et al. JOURNAL OF MOLECULAR BIOLOGY
- Deubiquitinase USP37 Is Activated by CDK2 to Antagonize APCCDH1 and Promote S Phase Entry
- (2011) XiaoDong Huang et al. MOLECULAR CELL
- USP47 Is a Deubiquitylating Enzyme that Regulates Base Excision Repair by Controlling Steady-State Levels of DNA Polymerase β
- (2011) Jason L. Parsons et al. MOLECULAR CELL
- Systematic and Quantitative Assessment of the Ubiquitin-Modified Proteome
- (2011) Woong Kim et al. MOLECULAR CELL
- Deubiquitinases in cancer: new functions and therapeutic options
- (2011) J M Fraile et al. ONCOGENE
- Absence of ataxin-3 leads to cytoskeletal disorganization and increased cell death
- (2010) Ana-João Rodrigues et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- USP10 Regulates p53 Localization and Stability by Deubiquitinating p53
- (2010) Jian Yuan et al. CELL
- The Prp19 complex and the Usp4Sart3 deubiquitinating enzyme control reversible ubiquitination at the spliceosome
- (2010) E. J. Song et al. GENES & DEVELOPMENT
- The Machado–Joseph disease-associated mutant form of ataxin-3 regulates parkin ubiquitination and stability
- (2010) Thomas M. Durcan et al. HUMAN MOLECULAR GENETICS
- Regulation of Epidermal Growth Factor Receptor Ubiquitination and Trafficking by the USP8·STAM Complex
- (2010) Ilana Berlin et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- WDR20 Regulates Activity of the USP12·UAF1 Deubiquitinating Enzyme Complex
- (2010) Younghoon Kee et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Further Insight into Substrate Recognition by USP7: Structural and Biochemical Analysis of the HdmX and Hdm2 Interactions with USP7
- (2010) Feroz Sarkari et al. JOURNAL OF MOLECULAR BIOLOGY
- Trimming of Ubiquitin Chains by Proteasome-associated Deubiquitinating Enzymes
- (2010) Min Jae Lee et al. MOLECULAR & CELLULAR PROTEOMICS
- The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression
- (2010) H. Yu et al. MOLECULAR AND CELLULAR BIOLOGY
- CYLD Tidies Up Dishevelled Signaling
- (2010) David Komander MOLECULAR CELL
- Enhancement of proteasome activity by a small-molecule inhibitor of USP14
- (2010) Byung-Hoon Lee et al. NATURE
- Lys11-linked ubiquitin chains adopt compact conformations and are preferentially hydrolyzed by the deubiquitinase Cezanne
- (2010) Anja Bremm et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ubiquitin vinyl methyl ester binding orients the misaligned active site of the ubiquitin hydrolase UCHL1 into productive conformation
- (2010) D. A. Boudreaux et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Dom34:Hbs1 Promotes Subunit Dissociation and Peptidyl-tRNA Drop-Off to Initiate No-Go Decay
- (2010) C. J. Shoemaker et al. SCIENCE
- JAB1/CSN5: a new player in cell cycle control and cancer
- (2010) Terry J Shackleford et al. Cell Division
- Interplay between p53-family, their regulators, and PARPs in DNA repair
- (2010) S. Emami Clinics and Research in Hepatology and Gastroenterology
- COP9-Associated CSN5 Regulates Exosomal Protein Deubiquitination and Sorting
- (2009) Yuelong Liu et al. AMERICAN JOURNAL OF PATHOLOGY
- Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes
- (2009) Francisca E. Reyes-Turcu et al. Annual Review of Biochemistry
- Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
- (2009) Daniel Finley Annual Review of Biochemistry
- Mitochondrial dysfunction in Parkinson's disease
- (2009) Konstanze F. Winklhofer et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- Quantitative Proteomics Reveals the Function of Unconventional Ubiquitin Chains in Proteasomal Degradation
- (2009) Ping Xu et al. CELL
- CYLD: a tumor suppressor deubiquitinase regulating NF-κB activation and diverse biological processes
- (2009) S-C Sun CELL DEATH AND DIFFERENTIATION
- CYLD negatively regulates cell-cycle progression by inactivating HDAC6 and increasing the levels of acetylated tubulin
- (2009) Sara A Wickström et al. EMBO JOURNAL
- The ER-resident ubiquitin-specific protease 19 participates in the UPR and rescues ERAD substrates
- (2009) Gerco C Hassink et al. EMBO REPORTS
- Ubiquitin Carboxyl-Terminal Hydrolase L3 Promotes Insulin Signaling and Adipogenesis
- (2009) Mari Suzuki et al. ENDOCRINOLOGY
- NBA1, a new player in the Brca1 A complex, is required for DNA damage resistance and checkpoint control
- (2009) B. Wang et al. GENES & DEVELOPMENT
- Proteotoxic stress increases nuclear localization of ataxin-3
- (2009) Christopher P. Reina et al. HUMAN MOLECULAR GENETICS
- CK2-dependent phosphorylation determines cellular localization and stability of ataxin-3
- (2009) Thorsten Mueller et al. HUMAN MOLECULAR GENETICS
- The Otubain YOD1 Is a Deubiquitinating Enzyme that Associates with p97 to Facilitate Protein Dislocation from the ER
- (2009) Robert Ernst et al. MOLECULAR CELL
- Phosphorylation of the Tumor Suppressor CYLD by the Breast Cancer Oncogene IKKɛ Promotes Cell Transformation
- (2009) Jessica E. Hutti et al. MOLECULAR CELL
- Building ubiquitin chains: E2 enzymes at work
- (2009) Yihong Ye et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Ubiquitin-like protein activation by E1 enzymes: the apex for downstream signalling pathways
- (2009) Brenda A. Schulman et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Breaking the chains: structure and function of the deubiquitinases
- (2009) David Komander et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The ubiquitin-specific protease USP47 is a novel β-TRCP interactor regulating cell survival
- (2009) A Peschiaroli et al. ONCOGENE
- Oxygen Toxicity and Reactive Oxygen Species: The Devil Is in the Details
- (2009) Richard L Auten et al. PEDIATRIC RESEARCH
- The proteasome: Overview of structure and functions
- (2009) Keiji TANAKA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Redox Regulation of Cell Survival
- (2008) Dunyaporn Trachootham et al. ANTIOXIDANTS & REDOX SIGNALING
- Protein partners of deubiquitinating enzymes
- (2008) Karen H. Ventii et al. BIOCHEMICAL JOURNAL
- Structural basis and specificity of human otubain 1-mediated deubiquitination
- (2008) Mariola J. Edelmann et al. BIOCHEMICAL JOURNAL
- The Cdc14B-Cdh1-Plk1 Axis Controls the G2 DNA-Damage-Response Checkpoint
- (2008) Florian Bassermann et al. CELL
- Polyubiquitin chains: functions, structures, and mechanisms
- (2008) W. Li et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Deubiquitination of CXCR4 by USP14 Is Critical for Both CXCL12-induced CXCR4 Degradation and Chemotaxis but Not ERK Activation
- (2008) Marjelo A. Mines et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hydrogen Peroxide Prolongs Nuclear Localization of NF-κB in Activated Cells by Suppressing Negative Regulatory Mechanisms
- (2008) Karine Enesa et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- UAF1 Is a Subunit of Multiple Deubiquitinating Enzyme Complexes
- (2008) Martin A. Cohn et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- USP19 Deubiquitinating Enzyme Supports Cell Proliferation by Stabilizing KPC1, a Ubiquitin Ligase for p27Kip1
- (2008) Y. Lu et al. MOLECULAR AND CELLULAR BIOLOGY
- Mature ribosomes are selectively degraded upon starvation by an autophagy pathway requiring the Ubp3p/Bre5p ubiquitin protease
- (2008) Claudine Kraft et al. NATURE CELL BIOLOGY
- Reconciling the chemistry and biology of reactive oxygen species
- (2008) Christine C Winterbourn Nature Chemical Biology
- Molecular Basis for the Unique Deubiquitinating Activity of the NF-κB Inhibitor A20
- (2007) Su-Chang Lin et al. JOURNAL OF MOLECULAR BIOLOGY
- Relative Structural and Functional Roles of Multiple Deubiquitylating Proteins Associated with Mammalian 26S Proteasome
- (2007) Elena Koulich et al. MOLECULAR BIOLOGY OF THE CELL
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