BRCA1-associated Protein 1 (BAP1) Deubiquitinase Antagonizes the Ubiquitin-mediated Activation of FoxK2 Target Genes

The forkhead transcription factor FOXK2 acts as a chromatin targeting factor for the BAP1-containing histone deubiquitinase complex

(2014) Zongling Ji et al.   NUCLEIC ACIDS RESEARCH

Germline BAP1 Mutations Predispose to Renal Cell Carcinomas

(2013) Tatiana Popova et al.   AMERICAN JOURNAL OF HUMAN GENETICS

BAP1 deficiency causes loss of melanocytic cell identity in uveal melanoma

(2013) Katie A Matatall et al.   BMC CANCER

A Novel Germline Mutation in BAP1 Predisposes to Familial Clear-Cell Renal Cell Carcinoma

(2013) M. N. Farley et al.   MOLECULAR CANCER RESEARCH

The Aurora B Kinase and the Polycomb Protein Ring1B Combine to Regulate Active Promoters in Quiescent Lymphocytes

(2013) Alberto Frangini et al.   MOLECULAR CELL

Exome sequencing identifies distinct mutational patterns in liver fluke–related and non-infection-related bile duct cancers

(2013) Waraporn Chan-on et al.   NATURE GENETICS

Exome sequencing identifies frequent inactivating mutations in BAP1, ARID1A and PBRM1 in intrahepatic cholangiocarcinomas

(2013) Yuchen Jiao et al.   NATURE GENETICS

Foxk1 recruits the Sds3 complex and represses gene expression in myogenic progenitors

(2012) Xiaozhong Shi et al.   BIOCHEMICAL JOURNAL

Live-cell monitoring of periodic gene expression in synchronous human cells identifies Forkhead genes involved in cell cycle control

(2012) Gavin D. Grant et al.   MOLECULAR BIOLOGY OF THE CELL

PCGF Homologs, CBX Proteins, and RYBP Define Functionally Distinct PRC1 Family Complexes

(2012) Zhonghua Gao et al.   MOLECULAR CELL

BAP1 loss defines a new class of renal cell carcinoma

(2012) Samuel Peña-Llopis et al.   NATURE GENETICS

Loss of the Tumor Suppressor BAP1 Causes Myeloid Transformation

(2012) A. Dey et al.   SCIENCE

The role of the histone H2A ubiquitinase Sce in Polycomb repression

(2011) L. Gutierrez et al.   DEVELOPMENT

Germline BAP1 mutation predisposes to uveal melanoma, lung adenocarcinoma, meningioma, and other cancers

(2011) M. H. Abdel-Rahman et al.   JOURNAL OF MEDICAL GENETICS

The Forkhead Transcription Factor FOXK2 Promotes AP-1-Mediated Transcriptional Regulation

(2011) Z. Ji et al.   MOLECULAR AND CELLULAR BIOLOGY

The nuclear deubiquitinase BAP1 is commonly inactivated by somatic mutations and 3p21.1 losses in malignant pleural mesothelioma

(2011) Matthew Bott et al.   NATURE GENETICS

Frequent mutations of genes encoding ubiquitin-mediated proteolysis pathway components in clear cell renal cell carcinoma

(2011) Guangwu Guo et al.   NATURE GENETICS

Germline mutations in BAP1 predispose to melanocytic tumors

(2011) Thomas Wiesner et al.   NATURE GENETICS

Germline BAP1 mutations predispose to malignant mesothelioma

(2011) Joseph R Testa et al.   NATURE GENETICS

Cell Cycle-dependent Regulation of the Forkhead Transcription Factor FOXK2 by CDK·Cyclin Complexes

(2010) Anett Marais et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Adenovirus Type 5 E1A and E6 Proteins of Low-Risk Cutaneous Beta-Human Papillomaviruses Suppress Cell Transformation through Interaction with FOXK1/K2 Transcription Factors

(2010) J. Komorek et al.   JOURNAL OF VIROLOGY

The Ubiquitin Carboxyl Hydrolase BAP1 Forms a Ternary Complex with YY1 and HCF-1 and Is a Critical Regulator of Gene Expression

(2010) H. Yu et al.   MOLECULAR AND CELLULAR BIOLOGY

Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB

(2010) Johanna C. Scheuermann et al.   NATURE

Frequent Mutation of BAP1 in Metastasizing Uveal Melanomas

(2010) J. W. Harbour et al.   SCIENCE

Defining the Human Deubiquitinating Enzyme Interaction Landscape

(2009) Mathew E. Sowa et al.   CELL

The Deubiquitinating Enzyme BAP1 Regulates Cell Growth via Interaction with HCF-1

(2009) Yuichi J. Machida et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Association of C-Terminal Ubiquitin Hydrolase BRCA1-Associated Protein 1 with Cell Cycle Regulator Host Cell Factor 1

(2009) S. Misaghi et al.   MOLECULAR AND CELLULAR BIOLOGY

The evolution of Fox genes and their role in development and disease

(2009) Sridhar Hannenhalli et al.   NATURE REVIEWS GENETICS

BRCA1-Associated Protein-1 Is a Tumor Suppressor that Requires Deubiquitinating Activity and Nuclear Localization

(2008) K. H. Ventii et al.   CANCER RESEARCH

Structure and Function of the Phosphothreonine-Specific FHA Domain

(2008) A. Mahajan et al.   Science Signaling