Systematic characterization of deubiquitylating enzymes for roles in maintaining genome integrity

Fine-Tuning of DNA Damage-Dependent Ubiquitination by OTUB2 Supports the DNA Repair Pathway Choice

(2014) Kiyoko Kato et al.   MOLECULAR CELL

Transcriptionally active chromatin recruits homologous recombination at DNA double-strand breaks

(2014) François Aymard et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ubiquitin-Specific Protease 5 Is Required for the Efficient Repair of DNA Double-Strand Breaks

(2014) Satoshi Nakajima et al.   PLoS One

The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability

(2013) Jin-Na Min et al.   CELL RESEARCH

Nucleosome remodelers in double-strand break repair

(2013) Andrew Seeber et al.   CURRENT OPINION IN GENETICS & DEVELOPMENT

The Deubiquitylating Enzyme USP44 Counteracts the DNA Double-strand Break Response Mediated by the RNF8 and RNF168 Ubiquitin Ligases

(2013) Anna Mosbech et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Regulation of DNA Damage Responses by Ubiquitin and SUMO

(2013) Stephen P. Jackson et al.   MOLECULAR CELL

Tumor suppressor and deubiquitinase BAP1 promotes DNA double-strand break repair

(2013) H. Yu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Ubiquitin Code

(2012) David Komander et al.   Annual Review of Biochemistry

A high-throughput, flow cytometry-based method to quantify DNA-end resection in mammalian cells

(2012) Josep V. Forment et al.   CYTOMETRY PART A

RNF4, a SUMO-targeted ubiquitin E3 ligase, promotes DNA double-strand break repair

(2012) Y. Galanty et al.   GENES & DEVELOPMENT

Skp1-Cul1-F-box Ubiquitin Ligase (SCFβTrCP)-mediated Destruction of the Ubiquitin-specific Protease USP37 during G2-phase Promotes Mitotic Entry

(2012) Amy C. Burrows et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ATM-Dependent Downregulation of USP7/HAUSP by PPM1G Activates p53 Response to DNA Damage

(2012) Svetlana V. Khoronenkova et al.   MOLECULAR CELL

Dynamics of DNA damage response proteins at DNA breaks: a focus on protein modifications

(2011) S. E. Polo et al.   GENES & DEVELOPMENT

Subunit Organization of the Human INO80 Chromatin Remodeling Complex

(2011) Lu Chen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Ino80 Mediates Double-Strand Break Repair through Its Role in DNA End Strand Resection

(2011) A. Gospodinov et al.   MOLECULAR AND CELLULAR BIOLOGY

Tracking genome engineering outcome at individual DNA breakpoints

(2011) Michael T Certo et al.   NATURE METHODS

Human INO80 chromatin-remodelling complex contributes to DNA double-strand break repair via the expression ofRad54BandXRCC3genes

(2010) Eun-Jung Park et al.   BIOCHEMICAL JOURNAL

A screen for deubiquitinating enzymes involved in the G2/M checkpoint identifies USP50 as a regulator of HSP90-dependent Wee1 stability

(2010) Bernadette Aressy et al.   CELL CYCLE

Sensitivity to Poly(ADP-ribose) Polymerase (PARP) Inhibition Identifies Ubiquitin-specific Peptidase 11 (USP11) as a Regulator of DNA Double-strand Break Repair

(2010) Timothy D. Wiltshire et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Non-canonical inhibition of DNA damage-dependent ubiquitination by OTUB1

(2010) Shinichiro Nakada et al.   NATURE

Regulation and Cellular Roles of Ubiquitin-Specific Deubiquitinating Enzymes

(2009) Francisca E. Reyes-Turcu et al.   Annual Review of Biochemistry

Human CtIP Mediates Cell Cycle Control of DNA End Resection and Double Strand Break Repair

(2009) Pablo Huertas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian SUMO E3-ligases PIAS1 and PIAS4 promote responses to DNA double-strand breaks

(2009) Yaron Galanty et al.   NATURE

Breaking the chains: structure and function of the deubiquitinases

(2009) David Komander et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

BRCA1-Associated Protein 1 Interferes with BRCA1/BARD1 RING Heterodimer Activity

(2008) H. Nishikawa et al.   CANCER RESEARCH

Visualizing Spatiotemporal Dynamics of Multicellular Cell-Cycle Progression

(2008) Asako Sakaue-Sawano et al.   CELL

DNA helicases Sgs1 and BLM promote DNA double-strand break resection

(2008) S. Gravel et al.   GENES & DEVELOPMENT

RAD51 foci formation in response to DNA damage is modulated by TIP49

(2008) Anastas Gospodinov et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

DNA Damage Responses: Mechanisms and Roles in Human Disease: 2007 G.H.A. Clowes Memorial Award Lecture

(2008) M. B. Kastan   MOLECULAR CANCER RESEARCH

Distinct Modes of Regulation of the Uch37 Deubiquitinating Enzyme in the Proteasome and in the Ino80 Chromatin-Remodeling Complex

(2008) Tingting Yao et al.   MOLECULAR CELL