Midkine derived from cancer-associated fibroblasts promotes cisplatin-resistance via up-regulation of the expression of lncRNA ANRIL in tumour cells

The TLR3 Agonist Inhibit Drug Efflux and Sequentially Consolidates Low-Dose Cisplatin-Based Chemoimmunotherapy while Reducing Side Effects

(2017) Liang Ding et al.   MOLECULAR CANCER THERAPEUTICS

Cancer-associated fibroblasts mediated chemoresistance by a FOXO1/TGFβ1 signaling loop in esophageal squamous cell carcinoma

(2016) Hongfang Zhang et al.   MOLECULAR CARCINOGENESIS

Cancer-associated fibroblasts treated with cisplatin facilitates chemoresistance of lung adenocarcinoma through IL-11/IL-11R/STAT3 signaling pathway

(2016) Leilei Tao et al.   Scientific Reports

Long non-coding RNA ANRIL is up-regulated in bladder cancer and regulates bladder cancer cell proliferation and apoptosis through the intrinsic pathway

(2015) Hongxue Zhu et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Cancer-associated fibroblasts predict poor outcome and promote periostin-dependent invasion in oesophageal adenocarcinoma

(2015) Timothy J Underwood et al.   JOURNAL OF PATHOLOGY

PKCδ/midkine pathway drives hypoxia-induced proliferation and differentiation of human lung epithelial cells

(2014) Hanying Zhang et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

LncRNA: A link between RNA and cancer

(2014) Guodong Yang et al.   Biochimica et Biophysica Acta-Gene Regulatory Mechanisms

The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via  2 integrins (CD11/CD18)

(2014) L. T. Weckbach et al.   BLOOD

Measuring midkine: the utility of midkine as a biomarker in cancer and other diseases

(2014) D R Jones   BRITISH JOURNAL OF PHARMACOLOGY

ANRIL inhibits p15INK4b through the TGFβ1 signaling pathway in human esophageal squamous cell carcinoma

(2014) Deyu Chen et al.   CELLULAR IMMUNOLOGY

Long Noncoding RNA ANRIL Promotes Non-Small Cell Lung Cancer Cell Proliferation and Inhibits Apoptosis by Silencing KLF2 and P21 Expression

(2014) F.-q. Nie et al.   MOLECULAR CANCER THERAPEUTICS

Regulation of the anti-tumour immune response by cancer-associated fibroblasts

(2014) James Harper et al.   SEMINARS IN CANCER BIOLOGY

Involvement of midkine in neuroblastoma tumourigenesis

(2013) S Kishida et al.   BRITISH JOURNAL OF PHARMACOLOGY

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Midkine upregulates MICA/B expression in human gastric cancer cells and decreases natural killer cell cytotoxicity

(2012) Shuli Zhao et al.   CANCER IMMUNOLOGY IMMUNOTHERAPY

The Noncoding RNA MALAT1 Is a Critical Regulator of the Metastasis Phenotype of Lung Cancer Cells

(2012) T. Gutschner et al.   CANCER RESEARCH

Long noncoding RNA associated with microvascular invasion in hepatocellular carcinoma promotes angiogenesis and serves as a predictor for hepatocellular carcinoma patients' poor recurrence-free survival after hepatectomy

(2012) Sheng-Xian Yuan et al.   HEPATOLOGY

ERβ-Mediated Estradiol Enhances Epithelial Mesenchymal Transition of Lung Adenocarcinoma through Increasing Transcription of Midkine

(2012) Guangfeng Zhao et al.   MOLECULAR ENDOCRINOLOGY

Long non-coding RNAs and cancer: a new frontier of translational research?

(2012) R Spizzo et al.   ONCOGENE

Notch Signaling Activated by Replication Stress-Induced Expression of Midkine Drives Epithelial-Mesenchymal Transition and Chemoresistance in Pancreatic Cancer

(2011) C. Gungor et al.   CANCER RESEARCH

Long Noncoding RNA, Polycomb, and the Ghosts Haunting INK4b-ARF-INK4a Expression

(2011) F. Aguilo et al.   CANCER RESEARCH

Midkine induces epithelial-mesenchymal transition through Notch2/Jak2-Stat3 signaling in human keratinocytes

(2011) Yiping Huang et al.   CELL CYCLE

Stimulation of the midkine/ALK axis renders glioma cells resistant to cannabinoid antitumoral action

(2011) M Lorente et al.   CELL DEATH AND DIFFERENTIATION

The functional role of long non-coding RNA in human carcinomas

(2011) Ewan A Gibb et al.   Molecular Cancer

Molecular Mechanisms of Long Noncoding RNAs

(2011) Kevin C. Wang et al.   MOLECULAR CELL

Prognostic gene-expression signature of carcinoma-associated fibroblasts in non-small cell lung cancer

(2011) R. Navab et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Tumor-Host Interactions: A Far-Reaching Relationship

(2010) Sandra S. McAllister et al.   JOURNAL OF CLINICAL ONCOLOGY

Molecular Interplay of the Noncoding RNA ANRIL and Methylated Histone H3 Lysine 27 by Polycomb CBX7 in Transcriptional Silencing of INK4a

(2010) Kyoko L. Yap et al.   MOLECULAR CELL

Over-expressed and truncated midkines promote proliferation of BGC823 cells in vitro and tumor growth in vivo

(2008) Qing-Ling Wang et al.   WORLD JOURNAL OF GASTROENTEROLOGY