Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin
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Title
Activation PDGFR-α/AKT Mediated Signaling Pathways in Oral Squamous Cell Carcinoma by Mesenchymal Stem/Stromal Cells Promotes Anti-apoptosis and Decreased Sensitivity to Cisplatin
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 10, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2020-04-28
DOI
10.3389/fonc.2020.00552
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Note: Only part of the references are listed.- Variant isoforms of CD44 involves acquisition of chemoresistance to cisplatin and has potential as a novel indicator for identifying a cisplatin-resistant population in urothelial cancer
- (2018) Masayuki Hagiwara et al. BMC CANCER
- Bone marrow mesenchymal stem cells promote head and neck cancer progression through Periostin-mediated phosphoinositide 3-kinase/Akt/mammalian target of rapamycin
- (2018) Chuanxia Liu et al. CANCER SCIENCE
- Reverse of non-small cell lung cancer drug resistance induced by cancer-associated fibroblasts via a paracrine pathway
- (2018) Quanhui Zhang et al. CANCER SCIENCE
- PDGFRA mRNA overexpression is associated with regional metastasis and reduced survival in oral squamous cell carcinoma
- (2018) Hui Shan Ong et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- PDGFRA mRNA is overexpressed in oral cancer patients as compared to normal subjects with a significant trend of overexpression among tobacco users
- (2017) Hui Shan Ong et al. JOURNAL OF ORAL PATHOLOGY & MEDICINE
- Cetuximab Resistance in Head and Neck Cancer Is Mediated by EGFR-K 521 Polymorphism
- (2016) Friederike Braig et al. CANCER RESEARCH
- PDGF-AA mediates mesenchymal stromal cell chemotaxis to the head and neck squamous cell carcinoma tumor microenvironment
- (2016) Tammara L. Watts et al. Journal of Translational Medicine
- Nivolumab for Recurrent Squamous-Cell Carcinoma of the Head and Neck
- (2016) Robert L. Ferris et al. NEW ENGLAND JOURNAL OF MEDICINE
- Platelet derived growth factor receptor alpha mediates nodal metastases in papillary thyroid cancer by driving the epithelial-mesenchymal transition
- (2016) Esther Ekpe-Adewuyi et al. Oncotarget
- Mesenchymal Stem Cells Promote Pancreatic Tumor Growth by Inducing Alternative Polarization of Macrophages
- (2016) Esha Mathew et al. NEOPLASIA
- Mesenchymal stem cells are enriched in head neck squamous cell carcinoma, correlates with tumour size and inhibit T-cell proliferation
- (2015) F Liotta et al. BRITISH JOURNAL OF CANCER
- Tracking and Functional Characterization of Epithelial-Mesenchymal Transition and Mesenchymal Tumor Cells during Prostate Cancer Metastasis
- (2015) M. Ruscetti et al. CANCER RESEARCH
- Cancer Stem Cells: Targeting the Roots of Cancer, Seeds of Metastasis, and Sources of Therapy Resistance
- (2015) V. Adorno-Cruz et al. CANCER RESEARCH
- TTP mediates cisplatin-induced apoptosis of head and neck cancer cells by down-regulating the expression ofBcl-2
- (2015) Su Bien Park et al. JOURNAL OF CHEMOTHERAPY
- Phosphorylation of AKT: a Mutational Analysis.
- (2015) Jonathan R. Hart et al. Oncotarget
- Functional Kinomics Identifies Candidate Therapeutic Targets in Head and Neck Cancer
- (2014) R. Moser et al. CLINICAL CANCER RESEARCH
- Tumor Microenvironment in Head and Neck Squamous Cell Carcinoma
- (2014) Joseph M. Curry et al. SEMINARS IN ONCOLOGY
- Crenolanib, a PDGFR inhibitor, suppresses lung cancer cell proliferation and inhibits tumor growth in vivo
- (2014) Ping Wang et al. OncoTargets and Therapy
- Crenolanib is a potent inhibitor of FLT3 with activity against resistance-conferring point mutants
- (2013) A. Galanis et al. BLOOD
- Bone marrow cells as precursors of the tumor stroma
- (2013) Daniel L. Worthley et al. EXPERIMENTAL CELL RESEARCH
- Temporal characterization of lymphatic metastasis in an orthotopic mouse model of oral cancer
- (2013) Peter Szaniszlo et al. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK
- PDGF-induced PI3K-mediated signaling enhances the TGF-β-induced osteogenic differentiation of human mesenchymal stem cells in a TGF-β-activated MEK-dependent manner
- (2013) JUN YOKOTA et al. INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE
- Radiation-induced senescence in securin-deficient cancer cells promotes cell invasion involving the IL-6/STAT3 and PDGF-BB/PDGFR pathways
- (2013) Yi-Chu Yu et al. Scientific Reports
- Mesenchymal stem cells regulate epithelial-mesenchymal transition and tumor progression of pancreatic cancer cells
- (2012) Ayano Kabashima-Niibe et al. CANCER SCIENCE
- Crenolanib Inhibits the Drug-Resistant PDGFRA D842V Mutation Associated with Imatinib-Resistant Gastrointestinal Stromal Tumors
- (2012) M. C. Heinrich et al. CLINICAL CANCER RESEARCH
- The reactive stroma microenvironment and prostate cancer progression
- (2012) David A Barron et al. ENDOCRINE-RELATED CANCER
- Stroma-directed imatinib therapy impairs the tumor-promoting effect of bone marrow-derived mesenchymal stem cells in an orthotopic transplantation model of colon cancer
- (2012) Kei Shinagawa et al. INTERNATIONAL JOURNAL OF CANCER
- Akt phosphorylation on Thr308 but not on Ser473 correlates with Akt protein kinase activity in human non-small cell lung cancer
- (2011) E E Vincent et al. BRITISH JOURNAL OF CANCER
- Mesenchymal Stem Cells Induce Resistance to Chemotherapy through the Release of Platinum-Induced Fatty Acids
- (2011) Jeanine M.L. Roodhart et al. CANCER CELL
- Bone Marrow-Derived Myofibroblasts Contribute to the Mesenchymal Stem Cell Niche and Promote Tumor Growth
- (2011) Michael Quante et al. CANCER CELL
- Breast Cancer Stem Cells Are Regulated by Mesenchymal Stem Cells through Cytokine Networks
- (2011) Suling Liu et al. CANCER RESEARCH
- TP53 Disruptive Mutations Lead to Head and Neck Cancer Treatment Failure through Inhibition of Radiation-Induced Senescence
- (2011) H. D. Skinner et al. CLINICAL CANCER RESEARCH
- Vandetanib Restores Head and Neck Squamous Cell Carcinoma Cells' Sensitivity to Cisplatin and Radiation In Vivo and In Vitro
- (2011) D. Sano et al. CLINICAL CANCER RESEARCH
- The Role of Tumor Stroma in Cancer Progression and Prognosis: Emphasis on Carcinoma-Associated Fibroblasts and Non-small Cell Lung Cancer
- (2010) Roy M. Bremnes et al. Journal of Thoracic Oncology
- Mesenchymal Stem Cell Transition to Tumor-Associated Fibroblasts Contributes to Fibrovascular Network Expansion and Tumor Progression
- (2009) Erika L. Spaeth et al. PLoS One
- Imatinib-Mediated Inactivation of Akt Regulates ABCG2 Function in Head and Neck Squamous Cell Carcinoma
- (2008) Theresa S. Chu et al. ARCHIVES OF OTOLARYNGOLOGY-HEAD & NECK SURGERY
- Carcinoma-Associated Fibroblast-Like Differentiation of Human Mesenchymal Stem Cells
- (2008) P. J. Mishra et al. CANCER RESEARCH
- Cancer Stem Cells in Head and Neck Squamous Cell Cancer
- (2008) Mark E.P. Prince et al. JOURNAL OF CLINICAL ONCOLOGY
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