Oxidative stress and impaired oligodendrocyte precursor cell differentiation in neurological disorders

Damage mechanisms to oligodendrocytes and white matter in CNS injury: the Australian context

(2020) Andrew Warnock et al.   JOURNAL OF NEUROTRAUMA

Myelin makes memories

(2020) R. Douglas Fields et al.   NATURE NEUROSCIENCE

Preservation of a remote fear memory requires new myelin formation

(2020) Simon Pan et al.   NATURE NEUROSCIENCE

Technical Feasibility and Physiological Relevance of Hypoxic Cell Culture Models

(2020) Jiri Pavlacky et al.   Frontiers in Endocrinology

Regulation of Oligodendrocyte Functions: Targeting Lipid Metabolism and Extracellular Matrix for Myelin Repair

(2020) Davide Marangon et al.   Journal of Clinical Medicine

Abnormal Upregulation of GPR17 Receptor Contributes to Oligodendrocyte Dysfunction in SOD1 G93A Mice

(2020) Elisabetta Bonfanti et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Changes in the oligodendrocyte progenitor cell proteome with ageing

(2020) Alerie G de la Fuente et al.   MOLECULAR & CELLULAR PROTEOMICS

Genetic identification of cell types underlying brain complex traits yields insights into the etiology of Parkinson’s disease

(2020) Julien Bryois et al.   NATURE GENETICS

A dual effect of ursolic acid to the treatment of multiple sclerosis through both immunomodulation and direct remyelination

(2020) Yuan Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer’s disease

(2020) Ping-Chieh Pao et al.   Nature Communications

Myelin Fat Facts: An Overview of Lipids and Fatty Acid Metabolism

(2020) Yannick Poitelon et al.   Cells

Gsta4 controls apoptosis of differentiating adult oligodendrocytes during homeostasis and remyelination via the mitochondria-associated Fas-Casp8-Bid-axis

(2020) Karl E. Carlström et al.   Nature Communications

Axonal mitochondria adjust in size depending on g ‐ratio of surrounding myelin during homeostasis and advanced remyelination

(2020) Benjamin V. Ineichen et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mitochondrial proteins: from biogenesis to functional networks

(2019) Nikolaus Pfanner et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Oligodendrocyte Progenitor Cells Become Regionally Diverse and Heterogeneous with Age

(2019) Sonia Olivia Spitzer et al.   NEURON

Behavioral and synaptic alterations relevant to obsessive-compulsive disorder in mice with increased EAAT3 expression

(2019) Claudia Delgado-Acevedo et al.   NEUROPSYCHOPHARMACOLOGY

Dynamics of oligodendrocyte generation in multiple sclerosis

(2019) Maggie S. Y. Yeung et al.   NATURE

Independent and cooperative roles of the Mek/ERK1/2-MAPK and PI3K/Akt/mTOR pathways during developmental myelination and in adulthood

(2019) Akihiro Ishii et al.   GLIA

Biotin attenuation of oxidative stress, mitochondrial dysfunction, lipid metabolism alteration and 7β-hydroxycholesterol-induced cell death in 158N murine oligodendrocytes

(2019) Randa Sghaier et al.   FREE RADICAL RESEARCH

Mitochondrial electron transport chain, ROS generation and uncoupling (Review)

(2019) Ru‑Zhou Zhao et al.   INTERNATIONAL JOURNAL OF MOLECULAR MEDICINE

Oligoprotective effect of metformin through the AMPK-dependent on restoration of mitochondrial hemostasis in the cuprizone-induced multiple sclerosis model

(2019) Seyed Hossein Hosseini Largani et al.   JOURNAL OF MOLECULAR HISTOLOGY

eIF2B Mutations Cause Mitochondrial Malfunction in Oligodendrocytes

(2019) Melisa Herrero et al.   NEUROMOLECULAR MEDICINE

Molecular Control of Oligodendrocyte Development

(2019) Benayahu Elbaz et al.   TRENDS IN NEUROSCIENCES

Pharmacological boost of DNA damage response and repair by enhanced biogenesis of DNA damage response RNAs

(2019) Ubaldo Gioia et al.   Scientific Reports

Epigenetics in cancer therapy and nanomedicine

(2019) Annalisa Roberti et al.   Clinical Epigenetics

Investigation of Oligodendrocyte Precursor Cell Differentiation by Quantitative Proteomics

(2019) Carmen Schoor et al.   PROTEOMICS

Therapeutic efficacy of dimethyl fumarate in relapsing-remitting multiple sclerosis associates with ROS pathway in monocytes

(2019) Karl E. Carlström et al.   Nature Communications

Targeting Phosphodiesterases—Towards a Tailor-Made Approach in Multiple Sclerosis Treatment

(2019) Melissa Schepers et al.   Frontiers in Immunology

Targeting age‐related differences in brain and cognition with multimodal imaging and connectome topography profiling

(2019) Alexander J. Lowe et al.   HUMAN BRAIN MAPPING

Nrf2 deficiency increases oligodendrocyte loss, demyelination, neuroinflammation and axonal damage in an MS animal model

(2019) Anna Nellessen et al.   METABOLIC BRAIN DISEASE

Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

(2019) Björn Neumann et al.   Cell Stem Cell

Interplay between MicroRNAs and Oxidative Stress in Neurodegenerative Diseases

(2019) Konovalova et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The Yin-Yang Regulation of Reactive Oxygen Species and MicroRNAs in Cancer

(2019) Kamesh R. Babu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Remyelination and ageing: Reversing the ravages of time

(2019) Bjoern Neumann et al.   Multiple Sclerosis Journal

Disruption of Oligodendrogenesis Impairs Memory Consolidation in Adult Mice

(2019) Patrick E. Steadman et al.   NEURON

The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells

(2019) Matheus Molina Silva et al.   Scientific Reports

Oligodendrocyte Intrinsic miR-27a Controls Myelination and Remyelination

(2019) Ajai Tripathi et al.   Cell Reports

Oligodendrocytes in Development, Myelin Generation and Beyond

(2019) Sarah Kuhn et al.   Cells

From OPC to Oligodendrocyte: An Epigenetic Journey

(2019) Assia Tiane et al.   Cells

Myrf guides target gene selection of transcription factor Sox10 during oligodendroglial development

(2019) Jessica Aprato et al.   NUCLEIC ACIDS RESEARCH

DNA damage-associated oligodendrocyte degeneration precedes amyloid pathology and contributes to Alzheimer's disease and dementia

(2018) Kai-Hei Tse et al.   Alzheimers & Dementia

AMPK-Mediated Regulation of Lipid Metabolism by Phosphorylation

(2018) Qi Wang et al.   BIOLOGICAL & PHARMACEUTICAL BULLETIN

Mitochondrial DNA damage and reactive oxygen species in neurodegenerative disease

(2018) Nadee Nissanka et al.   FEBS LETTERS

Advanced Glycation Endproducts Are Increased in the Animal Model of Multiple Sclerosis but Cannot Be Reduced by Pyridoxamine Treatment or Glyoxalase 1 Overexpression

(2018) Suzan Wetzels et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Deoxyribonucleic Acid Damage and Repair: Capitalizing on Our Understanding of the Mechanisms of Maintaining Genomic Integrity for Therapeutic Purposes

(2018) Jolene Helena et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Oligodendroglia Are Particularly Vulnerable to Oxidative Damage after NeurotraumaIn Vivo

(2018) Marcus K. Giacci et al.   JOURNAL OF NEUROSCIENCE

Lifelong cortical myelin plasticity and age-related degeneration in the live mammalian brain

(2018) Robert A. Hill et al.   NATURE NEUROSCIENCE

Roflumilast promotes memory recovery and attenuates white matter injury in aged rats subjected to chronic cerebral hypoperfusion

(2018) Amanda Santiago et al.   NEUROPHARMACOLOGY

Protective effects of a radical scavenger edaravone on oligodendrocyte precursor cells against oxidative stress

(2018) Hajime Takase et al.   NEUROSCIENCE LETTERS

From Oxidative Stress Damage to Pathways, Networks, and Autophagy via MicroRNAs

(2018) Nikolai Engedal et al.   Oxidative Medicine and Cellular Longevity

Oral N -acetylcysteine in the treatment of obsessive-compulsive disorder: A systematic review of the clinical evidence

(2018) José Paulo Couto et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mitochondria-derived ROS activate AMP-activated protein kinase (AMPK) indirectly

(2018) Elizabeth C Hinchy et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Nrf2 Signaling in Sodium Azide-Treated Oligodendrocytes Restores Mitochondrial Functions

(2018) Annette Liessem-Schmitz et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Activity-dependent central nervous system myelination throughout life

(2018) Omar de Faria et al.   JOURNAL OF NEUROCHEMISTRY

Multimodal Enhancement of Remyelination by Exercise with a Pivotal Role for Oligodendroglial PGC1α

(2018) Samuel K. Jensen et al.   Cell Reports

Overview on the Effects of N-Acetylcysteine in Neurodegenerative Diseases

(2018) Giuseppe Tardiolo et al.   MOLECULES

The Role of Mitochondria in Reactive Oxygen Species Generation and Its Implications for Neurodegenerative Diseases

(2018) Saima Kausar et al.   Cells

Mechanisms of DNA damage, repair, and mutagenesis

(2017) Nimrat Chatterjee et al.   ENVIRONMENTAL AND MOLECULAR MUTAGENESIS

Pathophysiology of mitochondrial lipid oxidation: Role of 4-hydroxynonenal (4-HNE) and other bioactive lipids in mitochondria

(2017) Mengqing Xiao et al.   FREE RADICAL BIOLOGY AND MEDICINE

Chemistry and analysis of HNE and other prominent carbonyl-containing lipid oxidation compounds

(2017) Bebiana C. Sousa et al.   FREE RADICAL BIOLOGY AND MEDICINE

Sox8 and Sox10 jointly maintain myelin gene expression in oligodendrocytes

(2017) Tanja Turnescu et al.   GLIA

Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis

(2017) Suzan Wetzels et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial DNA Double-Strand Breaks in Oligodendrocytes Cause Demyelination, Axonal Injury, and CNS Inflammation

(2017) Pernille M. Madsen et al.   JOURNAL OF NEUROSCIENCE

DNA damage in the oligodendrocyte lineage and its role in brain aging

(2017) Kai-Hei Tse et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Multiscale network modeling of oligodendrocytes reveals molecular components of myelin dysregulation in Alzheimer’s disease

(2017) Andrew T. McKenzie et al.   Molecular Neurodegeneration

Active liver X receptor signaling in phagocytes in multiple sclerosis lesions

(2017) Jo Mailleux et al.   Multiple Sclerosis Journal

Regenerating CNS myelin — from mechanisms to experimental medicines

(2017) Robin J. M. Franklin et al.   NATURE REVIEWS NEUROSCIENCE

Epigenetics and Oxidative Stress in Aging

(2017) Amy Guillaumet-Adkins et al.   Oxidative Medicine and Cellular Longevity

Orexin activation counteracts decreases in nonexercise activity thermogenesis (NEAT) caused by high-fat diet

(2017) P.E. Bunney et al.   PHYSIOLOGY & BEHAVIOR

Folate Metabolism Regulates Oligodendrocyte Survival and Differentiation by Modulating AMPKα Activity

(2017) Qinjie Weng et al.   Scientific Reports

LRP1 regulates peroxisome biogenesis and cholesterol homeostasis in oligodendrocytes and is required for proper CNS myelin development and repair

(2017) Jing-Ping Lin et al.   eLife

Active liver X receptor signaling in phagocytes in multiple sclerosis lesions

(2017) Jo Mailleux et al.   Multiple Sclerosis Journal

Oxidative stress, prefrontal cortex hypomyelination and cognitive symptoms in schizophrenia

(2017) D A Maas et al.   Translational Psychiatry

Doublecortin in Oligodendrocyte Precursor Cells in the Adult Mouse Brain

(2017) Jenna J. Boulanger et al.   Frontiers in Neuroscience

Calcium and Mitochondrial Reactive Oxygen Species Generation: How to Read the Facts

(2017) Vera Adam-Vizi et al.   JOURNAL OF ALZHEIMERS DISEASE

Relapsing-remitting multiple sclerosis patients display an altered lipoprotein profile with dysfunctional HDL

(2017) Winde Jorissen et al.   Scientific Reports

Gene expression profiling of brain samples from patients with Lewy body dementia

(2016) Maciej Pietrzak et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Mitochondrial lipids in neurodegeneration

(2016) Andreas Aufschnaiter et al.   CELL AND TISSUE RESEARCH

Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study

(2016) Mara Colzani et al.   ChemMedChem

Movement and structure of mitochondria in oligodendrocytes and their myelin sheaths

(2016) Johanne E. Rinholm et al.   GLIA

N-Acetylcysteine in Depressive Symptoms and Functionality

(2016) Brisa S. Fernandes et al.   JOURNAL OF CLINICAL PSYCHIATRY

Reduced sterol regulatory element-binding protein (SREBP) processing through site-1 protease (S1P) inhibition alters oligodendrocyte differentiationin vitro

(2016) Hubert Monnerie et al.   JOURNAL OF NEUROCHEMISTRY

Oligodendrogliopathy in Multiple Sclerosis: Low Glycolytic Metabolic Rate Promotes Oligodendrocyte Survival

(2016) M. B. Rone et al.   JOURNAL OF NEUROSCIENCE

Contribution of the oligodendrocyte lineage to CNS repair and neurodegenerative pathologies

(2016) Reshmi Tognatta et al.   NEUROPHARMACOLOGY

Targeting demyelination and virtual hypoxia with high-dose biotin as a treatment for progressive multiple sclerosis

(2016) Frédéric Sedel et al.   NEUROPHARMACOLOGY

Diversity Matters: A Revised Guide to Myelination

(2016) Giulio Srubek Tomassy et al.   TRENDS IN CELL BIOLOGY

Reactive Oxygen Species Derived from NOX3 and NOX5 Drive Differentiation of Human Oligodendrocytes

(2016) Roberta Accetta et al.   Frontiers in Cellular Neuroscience

Oxidative stress signaling to chromatin in health and disease

(2016) Sarah Kreuz et al.   Epigenomics

Oxidative stress at low levels can induce clustered DNA lesions leading to NHEJ mediated mutations

(2016) Vyom Sharma et al.   Oncotarget

mTOR coordinates protein synthesis, mitochondrial activity and proliferation

(2015) Masahiro Morita et al.   CELL CYCLE

ROS-Mediated DNA Methylation Pattern Alterations in Carcinogenesis

(2015) Qihan Wu et al.   CURRENT DRUG TARGETS

How to make an oligodendrocyte

(2015) S. A. Goldman et al.   DEVELOPMENT

Resistance of glia-like central and peripheral neural stem cells to genetically induced mitochondrial dysfunction--differential effects on neurogenesis

(2015) B. Diaz-Castro et al.   EMBO REPORTS

Peroxisome proliferator activated receptor-γ agonists protect oligodendrocyte progenitors against tumor necrosis factor-alpha-induced damage: Effects on mitochondrial functions and differentiation

(2015) C. De Nuccio et al.   EXPERIMENTAL NEUROLOGY

Confocal Imaging–Guided Laser Ablation of Basal Cell Carcinomas: An Ex Vivo Study

(2015) Heidy Sierra et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

Thyroid-stimulating hormone decreases HMG-CoA reductase phosphorylation via AMP-activated protein kinase in the liver

(2015) Xiujuan Zhang et al.   JOURNAL OF LIPID RESEARCH

Transcription factors Sox10 and Sox2 functionally interact with positive transcription elongation factor b in Schwann cells

(2015) Juliane Arter et al.   JOURNAL OF NEUROCHEMISTRY

Demyelination Causes Adult CNS Progenitors to Revert to an Immature State and Express Immune Cues That Support Their Migration

(2015) S. Moyon et al.   JOURNAL OF NEUROSCIENCE

Differentiation of oligodendrocyte precursors is impaired in the prefrontal cortex in schizophrenia

(2015) Sarah A. Mauney et al.   SCHIZOPHRENIA RESEARCH

Depression as a Microglial Disease

(2015) Raz Yirmiya et al.   TRENDS IN NEUROSCIENCES

Oligodendrocytes: Myelination and Axonal Support

(2015) Mikael Simons et al.   Cold Spring Harbor Perspectives in Biology

Dimethyl fumarate modulates antioxidant and lipid metabolism in oligodendrocytes

(2015) He Huang et al.   Redox Biology

The Role of Oxidative Stress in Neurodegenerative Diseases

(2015) Geon Ha Kim et al.   Experimental Neurobiology

p38 Mitogen-Activated Protein Kinase Pathway Regulates Genes during Proliferation and Differentiation in Oligodendrocytes

(2015) Jeffery D. Haines et al.   PLoS One

Tumor necrosis factor-α impairs oligodendroglial differentiation through a mitochondria-dependent process

(2014) M Bonora et al.   CELL DEATH AND DIFFERENTIATION

Mitochondria, Energetics, Epigenetics, and Cellular Responses to Stress

(2014) Daniel T. Shaughnessy et al.   ENVIRONMENTAL HEALTH PERSPECTIVES

Adapting brain metabolism to myelination and long-range signal transduction

(2014) Johannes Hirrlinger et al.   GLIA

Dynamics of ten-eleven translocation hydroxylase family proteins and 5-hydroxymethylcytosine in oligodendrocyte differentiation

(2014) Xianghui Zhao et al.   GLIA

Shortened telomere length in white matter oligodendrocytes in major depression: potential role of oxidative stress

(2014) Attila Szebeni et al.   INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY

An RNA-Sequencing Transcriptome and Splicing Database of Glia, Neurons, and Vascular Cells of the Cerebral Cortex

(2014) Y. Zhang et al.   JOURNAL OF NEUROSCIENCE

Stem cell aging: mechanisms, regulators and therapeutic opportunities

(2014) Juhyun Oh et al.   NATURE MEDICINE

Motor skill learning requires active central myelination

(2014) I. A. McKenzie et al.   SCIENCE

Reactive Carbonyl SpeciesIn Vivo: Generation and Dual Biological Effects

(2014) Halyna M. Semchyshyn   TheScientificWorldJOURNAL

Astroglial PGC-1alpha increases mitochondrial antioxidant capacity and suppresses inflammation: implications for multiple sclerosis

(2014) Philip G Nijland et al.   Acta Neuropathologica Communications

mTOR: A Link from the Extracellular Milieu to Transcriptional Regulation of Oligodendrocyte Development

(2013) Teresa L. Wood et al.   ASN Neuro

Myelin peroxisomes – Essential organelles for the maintenance of white matter in the nervous system

(2013) Celia M. Kassmann   BIOCHIMIE

Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis

(2013) Alberto Camacho et al.   EUROPEAN JOURNAL OF NEUROSCIENCE

Nbngene inactivation in the CNS of mouse inhibits the myelinating ability of the mature cortical oligodendrocytes

(2013) Bo Liu et al.   GLIA

Modulation of Rho-Rock signaling pathway protects oligodendrocytes against cytokine toxicity via PPAR-α-dependent mechanism

(2013) Ajaib S. Paintlia et al.   GLIA

Sustained Activation of ERK1/2 MAPK in Oligodendrocytes and Schwann Cells Enhances Myelin Growth and Stimulates Oligodendrocyte Progenitor Expansion

(2013) A. Ishii et al.   JOURNAL OF NEUROSCIENCE

DNA damage and oxidative injury are associated with hypomyelination in the corpus callosum of newborn NbnCNS-delmice

(2013) B. Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Oligodendrocyte Dynamics in the Healthy Adult CNS: Evidence for Myelin Remodeling

(2013) Kaylene M. Young et al.   NEURON

Mechanisms regulating the development of oligodendrocytes and central nervous system myelin

(2013) S. Mitew et al.   NEUROSCIENCE

Inhibition of NADPH Oxidase Activation in Oligodendrocytes Reduces Cytotoxicity Following Trauma

(2013) Joshua T. Johnstone et al.   PLoS One

Oxidative Stress Interferes With White Matter Renewal After Prolonged Cerebral Hypoperfusion in Mice

(2013) Nobukazu Miyamoto et al.   STROKE

NMDA modulates oligodendrocyte differentiation of subventricular zone cells through PKC activation

(2013) Fabio Cavaliere et al.   Frontiers in Cellular Neuroscience

The Transcription Factors Sox10 and Myrf Define an Essential Regulatory Network Module in Differentiating Oligodendrocytes

(2013) Julia Hornig et al.   PLoS Genetics

Mitochondrial dysfunction and neurodegeneration in multiple sclerosis

(2013) Kimmy Su et al.   Frontiers in Physiology

Reduced expression of PGC-1α partly underlies mitochondrial changes and correlates with neuronal loss in multiple sclerosis cortex

(2012) Maarten E. Witte et al.   ACTA NEUROPATHOLOGICA

NADPH oxidase expression in active multiple sclerosis lesions in relation to oxidative tissue damage and mitochondrial injury

(2012) Marie T. Fischer et al.   BRAIN

Identification and Quantification of Oligodendrocyte Precursor Cells in Multiple System Atrophy, Progressive Supranuclear Palsy and Parkinson's Disease

(2012) Zeshan Ahmed et al.   BRAIN PATHOLOGY

Mitochondrial changes within axons in multiple sclerosis

(2012) Graham R. Campbell et al.   CURRENT OPINION IN NEUROLOGY

Olig2-dependent developmental fate switch of NG2 cells

(2012) X. Zhu et al.   DEVELOPMENT

Selective binding of nuclear alpha-synuclein to the PGC1alpha promoter under conditions of oxidative stress may contribute to losses in mitochondrial function: Implications for Parkinson’s disease

(2012) Almas Siddiqui et al.   FREE RADICAL BIOLOGY AND MEDICINE

Histone deacetylase activity is required for human oligodendrocyte progenitor differentiation

(2012) Gregory D. Conway et al.   GLIA

Redox implications of AMPK-mediated signal transduction beyond energetic clues

(2012) S. Cardaci et al.   JOURNAL OF CELL SCIENCE

Clusters of activated microglia in normal-appearing white matter show signs of innate immune activation

(2012) Jack van Horssen et al.   Journal of Neuroinflammation

Post-Translational Oxidative Modification and Inactivation of Mitochondrial Complex I in Epileptogenesis

(2012) K. Ryan et al.   JOURNAL OF NEUROSCIENCE

Minocycline protects oligodendroglial precursor cells against injury caused by oxygen-glucose deprivation

(2012) Thomas Schmitz et al.   JOURNAL OF NEUROSCIENCE RESEARCH

The Nrf2-antioxidant response element pathway: a target for regulating energy metabolism

(2012) Emilie E. Vomhof-DeKrey et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

nNOS mediated mitochondrial injury in LPS stimulated oligodendrocytes

(2012) S.-Y. Yao et al.   MITOCHONDRION

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

Evidence of oxidative stress in very long chain fatty acid – Treated oligodendrocytes and potentialization of ROS production using RNA interference-directed knockdown of ABCD1 and ACOX1 peroxisomal proteins

(2012) M. Baarine et al.   NEUROSCIENCE

Oligodendrocyte differentiation from adult multipotent stem cells is modulated by glutamate

(2012) F Cavaliere et al.   Cell Death & Disease

Oxidative damage in multiple sclerosis lesions

(2011) L. Haider et al.   BRAIN

Regulation of chromatin by histone modifications

(2011) Andrew J Bannister et al.   CELL RESEARCH

Epigenetic Modifications

(2011) Diane E. Handy et al.   CIRCULATION

A role for myelin-associated peroxisomes in maintaining paranodal loops and axonal integrity

(2011) Celia M. Kassmann et al.   FEBS LETTERS

The molecular basis of neurodegeneration in multiple sclerosis

(2011) Hans Lassmann et al.   FEBS LETTERS

Synapses between NG2 glia and neurons

(2011) Dominik Sakry et al.   JOURNAL OF ANATOMY

Peroxisome Proliferator-Activated Receptor γ Agonists Accelerate Oligodendrocyte Maturation and Influence Mitochondrial Functions and Oscillatory Ca2+Waves

(2011) Chiara De Nuccio et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Iron Efflux from Oligodendrocytes Is Differentially Regulated in Gray and White Matter

(2011) K. Schulz et al.   JOURNAL OF NEUROSCIENCE

Regulation of Oligodendrocyte Development and Myelination by Glucose and Lactate

(2011) J. E. Rinholm et al.   JOURNAL OF NEUROSCIENCE

The ERK2 Mitogen-Activated Protein Kinase Regulates the Timing of Oligodendrocyte Differentiation

(2011) S. L. Fyffe-Maricich et al.   JOURNAL OF NEUROSCIENCE

Peroxisome-Proliferator-Activated Receptor Gamma Coactivator 1   Contributes to Dysmyelination in Experimental Models of Huntington's Disease

(2011) Z. Xiang et al.   JOURNAL OF NEUROSCIENCE

Schwann Cell Mitochondrial Metabolism Supports Long-Term Axonal Survival and Peripheral Nerve Function

(2011) A. Viader et al.   JOURNAL OF NEUROSCIENCE

Age-associated neurodegeneration and oxidative damage to lipids, proteins and DNA

(2011) Zsolt Radak et al.   MOLECULAR ASPECTS OF MEDICINE

Protein modification by acrolein: Relevance to pathological conditions and inhibition by aldehyde sequestering agents

(2011) Giancarlo Aldini et al.   MOLECULAR NUTRITION & FOOD RESEARCH

DNA methylation in cancer development, diagnosis and therapy--multiple opportunities for genotoxic agents to act as methylome disruptors or remediators

(2011) J. Lewandowska et al.   MUTAGENESIS

Chemistry and biology of reactive oxygen species in signaling or stress responses

(2011) Bryan C Dickinson et al.   Nature Chemical Biology

MicroRNAs in Development and Disease

(2011) Danish Sayed et al.   PHYSIOLOGICAL REVIEWS

Neurite outgrowth inhibitor Nogo-A establishes spatial segregation and extent of oligodendrocyte myelination

(2011) S. Y. C. Chong et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Neuroinflammation in schizophrenia especially focused on the role of microglia

(2011) Akira Monji et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Mitochondrial DNA deletions and neurodegeneration in multiple sclerosis

(2010) Graham R. Campbell et al.   ANNALS OF NEUROLOGY

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End-Joining Pathway

(2010) Michael R. Lieber   Annual Review of Biochemistry

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Cells of the oligodendroglial lineage, myelination, and remyelination

(2010) Veronique E. Miron et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Oxidative modification to LDL receptor-related protein 1 in hippocampus from subjects with Alzheimer disease: Implications for Aβ accumulation in AD brain

(2010) Joshua B. Owen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Nrf2 and DJ1 are consistently upregulated in inflammatory multiple sclerosis lesions

(2010) Jack van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Injury and differentiation following inhibition of mitochondrial respiratory chain complex IV in rat oligodendrocytes

(2010) Iryna Ziabreva et al.   GLIA

Redox Signaling, Alkylation (Carbonylation) of Conserved Cysteines Inactivates Class I Histone Deacetylases 1, 2, and 3 and Antagonizes Their Transcriptional Repressor Function

(2010) Kelly Doyle et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Synergistic activity of interleukin-17 and tumor necrosis factor-α enhances oxidative stress-mediated oligodendrocyte apoptosis

(2010) Manjeet K. Paintlia et al.   JOURNAL OF NEUROCHEMISTRY

In vitro and in vivo induction and activation of nNOS by LPS in oligodendrocytes

(2010) S.Y. Yao et al.   JOURNAL OF NEUROIMMUNOLOGY

Activated Microglia Mediate Axoglial Disruption That Contributes to Axonal Injury in Multiple Sclerosis

(2010) Owain W. Howell et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Mechanisms of Regulation of Oligodendrocyte Development by p38 Mitogen-Activated Protein Kinase

(2010) L.-J. Chew et al.   JOURNAL OF NEUROSCIENCE

Developmental genetics of vertebrate glial–cell specification

(2010) David H. Rowitch et al.   NATURE

Aluminum induces neurodegeneration and its toxicity arises from increased iron accumulation and reactive oxygen species (ROS) production

(2010) Zhihao Wu et al.   NEUROBIOLOGY OF AGING

Regulation of Oligodendrocyte Differentiation and Myelination

(2010) B. Emery   SCIENCE

Epigenetic regulation of oligodendrocyte identity

(2010) Jia Liu et al.   TRENDS IN NEUROSCIENCES

Oligodendrocytes: biology and pathology

(2009) Monika Bradl et al.   ACTA NEUROPATHOLOGICA

Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities

(2009) Rao Muralikrishna Adibhatla et al.   ANTIOXIDANTS & REDOX SIGNALING

MicroRNA profiling of multiple sclerosis lesions identifies modulators of the regulatory protein CD47

(2009) Andreas Junker et al.   BRAIN

Two-tier transcriptional control of oligodendrocyte differentiation

(2009) Huiliang Li et al.   CURRENT OPINION IN NEUROBIOLOGY

On the biogenesis of myelin membranes: Sorting, trafficking and cell polarity

(2009) Wia Baron et al.   FEBS LETTERS

Co-localization ofNkx6.2andNkx2.2homeodomain proteins in differentiated myelinating oligodendrocytes

(2009) Jun Cai et al.   GLIA

Chronic expression of PPAR-δ by oligodendrocyte lineage cells in the injured rat spinal cord

(2009) Akshata Almad et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Neuroinflammation in Parkinson’s Disease

(2009) Jae-Kyung Lee et al.   Journal of Neuroimmune Pharmacology

Peroxisome Proliferator-Activated Receptor-γ Agonists Promote Differentiation and Antioxidant Defenses of Oligodendrocyte Progenitor Cells

(2009) Antonietta Bernardo et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Oxidative stress disrupts oligodendrocyte maturation

(2009) Heather Morein French et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Oligodendroglial differentiation induces mitochondrial genes and inhibition of mitochondrial function represses oligodendroglial differentiation

(2009) Robert Schoenfeld et al.   MITOCHONDRION

Human DNA methylomes at base resolution show widespread epigenomic differences

(2009) Ryan Lister et al.   NATURE

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the β-catenin–TCF interaction

(2009) Feng Ye et al.   NATURE NEUROSCIENCE

Cytokines and schizophrenia: Microglia hypothesis of schizophrenia

(2009) Akira Monji et al.   PSYCHIATRY AND CLINICAL NEUROSCIENCES

NADPH oxidase as a therapeutic target in Alzheimer's disease

(2008) Michelle L Block   BMC NEUROSCIENCE

Mitochondrial defects in acute multiple sclerosis lesions

(2008) Don Mahad et al.   BRAIN

Differentiation block of oligodendroglial progenitor cells as a cause for remyelination failure in chronic multiple sclerosis

(2008) T. Kuhlmann et al.   BRAIN

Maturation-dependent sensitivity of oligodendrocyte lineage cells to apoptosis: implications for normal development and disease

(2008) B D Butts et al.   CELL DEATH AND DIFFERENTIATION

Proliferation and differentiation of oligodendrocyte progenitor cells induced from rat embryonic neural precursor cells followed by flow cytometry

(2008) He‐Zuo Lü et al.   CYTOMETRY PART A

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

(2008) J. van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Modulation of peroxisome proliferator-activated receptor-α activity by N-acetyl cysteine attenuates inhibition of oligodendrocyte development in lipopolysaccharide stimulated mixed glial cultures

(2008) Manjeet K. Paintlia et al.   JOURNAL OF NEUROCHEMISTRY

Glutathione: Overview of its protective roles, measurement, and biosynthesis

(2008) Henry Jay Forman et al.   MOLECULAR ASPECTS OF MEDICINE

Environmental-induced oxidative stress in neurodegenerative disorders and aging

(2008) Lucia Migliore et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Age-dependent epigenetic control of differentiation inhibitors is critical for remyelination efficiency

(2008) Siming Shen et al.   NATURE NEUROSCIENCE

The role of mitochondrial DNA mutations in aging and sarcopenia: Implications for the mitochondrial vicious cycle theory of aging

(2007) A HIONA   EXPERIMENTAL GERONTOLOGY