Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
Published 2009 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Lipid Oxidation and Peroxidation in CNS Health and Disease: From Molecular Mechanisms to Therapeutic Opportunities
Authors
Keywords
-
Journal
ANTIOXIDANTS & REDOX SIGNALING
Volume 12, Issue 1, Pages 125-169
Publisher
Mary Ann Liebert Inc
Online
2009-07-23
DOI
10.1089/ars.2009.2668
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Iron Toxicity in Diseases of Aging: Alzheimer's Disease, Parkinson's Disease and Atherosclerosis
- (2017) Sandro Altamura et al. JOURNAL OF ALZHEIMERS DISEASE
- Phospholipase A2, reactive oxygen species, and lipid peroxidation in CNS pathologies
- (2011) Rao Muralikrishna Adibhatla et al. BMB Reports
- Lipid-based systemic delivery of siRNA
- (2009) Yu-Cheng Tseng et al. ADVANCED DRUG DELIVERY REVIEWS
- Small silencing RNAs: State-of-the-art
- (2009) Dirk Grimm ADVANCED DRUG DELIVERY REVIEWS
- siRNA delivery systems for cancer treatment
- (2009) Yu-Kyoung Oh et al. ADVANCED DRUG DELIVERY REVIEWS
- Mitochondrial Function, Morphology, and Axonal Transport in Amyotrophic Lateral Sclerosis
- (2009) Jordi Magrané et al. ANTIOXIDANTS & REDOX SIGNALING
- Glutamate Transporters and the Excitotoxic Path to Motor Neuron Degeneration in Amyotrophic Lateral Sclerosis
- (2009) Emily Foran et al. ANTIOXIDANTS & REDOX SIGNALING
- Polyamine catabolism and disease
- (2009) Robert A. Casero et al. BIOCHEMICAL JOURNAL
- Cholesterol transport in steroid biosynthesis: Role of protein–protein interactions and implications in disease states
- (2009) Malena B. Rone et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Niemann–Pick C2 (NPC2) and intracellular cholesterol trafficking
- (2009) Judith Storch et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS
- Resolvin D1 controls inflammation initiated by glutathione-lipid conjugates formed during oxidative stress
- (2009) M Spite et al. BRITISH JOURNAL OF PHARMACOLOGY
- Future Role for Selective Phospholipase A2 Inhibitors in the Prevention of Atherosclerotic Cardiovascular Disease
- (2009) Robert S. Rosenson CARDIOVASCULAR DRUGS AND THERAPY
- Sphingomyelinases: their regulation and roles in cardiovascular pathophysiology
- (2009) Catherine Pavoine et al. CARDIOVASCULAR RESEARCH
- Roles and regulation of secretory and lysosomal acid sphingomyelinase
- (2009) Russell W. Jenkins et al. CELLULAR SIGNALLING
- Brain oxidative stress after traumatic brain injury … cool it?*
- (2009) Douglas D. Fraser et al. CRITICAL CARE MEDICINE
- Therapeutic hypothermia preserves antioxidant defenses after severe traumatic brain injury in infants and children*
- (2009) Hülya Bayr et al. CRITICAL CARE MEDICINE
- The genetics of Parkinson's syndromes: a critical review
- (2009) John Hardy et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- Oxidative Imbalance in Nonstimulated X-Adrenoleukodystrophy-Derived Lymphoblasts
- (2009) Takuhiro Uto et al. DEVELOPMENTAL NEUROSCIENCE
- Cytochrome c/cardiolipin relations in mitochondria: a kiss of death
- (2009) Valerian E. Kagan et al. FREE RADICAL BIOLOGY AND MEDICINE
- Oxidative stress and mitochondrial dysfunction as determinants of ischemic neuronal death and survival
- (2009) Kuniyasu Niizuma et al. JOURNAL OF NEUROCHEMISTRY
- Transglutaminases and neurodegeneration
- (2009) Thomas M. Jeitner et al. JOURNAL OF NEUROCHEMISTRY
- Differential sensitivity of oligodendrocytes and motor neurons to reactive nitrogen species: implications for multiple sclerosis
- (2009) Amy Bishop et al. JOURNAL OF NEUROCHEMISTRY
- Combination therapy with Coenzyme Q10and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases
- (2009) Lichuan Yang et al. JOURNAL OF NEUROCHEMISTRY
- Iron accumulation in syndromes of neurodegeneration with brain iron accumulation 1 and 2: causative or consequential?
- (2009) S A Schneider et al. JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY
- Neuronal PPAR Deficiency Increases Susceptibility to Brain Damage after Cerebral Ischemia
- (2009) X. Zhao et al. JOURNAL OF NEUROSCIENCE
- Effects of 1-H-indole-3-glyoxamide (A-002) on concentration of secretory phospholipase A2 (PLASMA study): a phase II double-blind, randomised, placebo-controlled trial
- (2009) Robert S Rosenson et al. LANCET
- The curious case of clioquinol
- (2009) Lauren Cahoon NATURE MEDICINE
- Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
- (2009) Peter Fraisl et al. NATURE REVIEWS DRUG DISCOVERY
- Brain iron homeostasis and neurodegenerative disease
- (2009) E. E. Benarroch NEUROLOGY
- Apolipoprotein E-genotype dependent hippocampal and cortical responses to traumatic brain injury
- (2009) F. Crawford et al. NEUROSCIENCE
- Nrf2-mediated neuroprotection in the MPTP mouse model of Parkinson's disease: Critical role for the astrocyte
- (2009) Pei-Chun Chen et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Statins: Mechanisms of neuroprotection
- (2009) Peter J. van der Most et al. PROGRESS IN NEUROBIOLOGY
- The distinct roles of cyclooxygenase-1 and -2 in neuroinflammation: implications for translational research
- (2009) Sang-Ho Choi et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Lipoprotein-Associated Phospholipase A2: A Risk Marker or a Risk Factor?
- (2008) Amir Lerman et al. AMERICAN JOURNAL OF CARDIOLOGY
- Decline in NRF2-regulated Antioxidants in Chronic Obstructive Pulmonary Disease Lungs Due to Loss of Its Positive Regulator, DJ-1
- (2008) Deepti Malhotra et al. AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE
- Multiple Sclerosis: An Immune or Neurodegenerative Disorder?
- (2008) Bruce D. Trapp et al. Annual Review of Neuroscience
- Acid Sphingomyelinase Promotes Lipoprotein Retention Within Early Atheromata and Accelerates Lesion Progression
- (2008) Cecilia M. Devlin et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Improved resistance to serum oxidation in Gilbert's syndrome: A mechanism for cardiovascular protection
- (2008) Andrew C. Bulmer et al. ATHEROSCLEROSIS
- Acrolein, IL-6 and CRP as markers of silent brain infarction
- (2008) Madoka Yoshida et al. ATHEROSCLEROSIS
- Acrolein toxicity: Comparison with reactive oxygen species
- (2008) Madoka Yoshida et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Mutant huntingtin activates Nrf2-responsive genes and impairs dopamine synthesis in a PC12 model of Huntington's disease
- (2008) Willeke MC van Roon-Mom et al. BMC MOLECULAR BIOLOGY
- A defect of sphingolipid metabolism modifies the properties of normal appearing white matter in multiple sclerosis
- (2008) David Wheeler et al. BRAIN
- Stress-Response Hormesis and Aging: “That which Does Not Kill Us Makes Us Stronger”
- (2008) David Gems et al. Cell Metabolism
- Effects of the Direct Lipoprotein-Associated Phospholipase A 2 Inhibitor Darapladib on Human Coronary Atherosclerotic Plaque
- (2008) Patrick W. Serruys et al. CIRCULATION
- Activation of Mitochondrial Biogenesis by Hormesis
- (2008) Motoaki Sano et al. CIRCULATION RESEARCH
- Tissue Plasminogen Activator (tPA) and Matrix Metalloproteinases in the Pathogenesis of Stroke: Therapeutic Strategies
- (2008) Rao Adibhatla et al. CNS & Neurological Disorders-Drug Targets
- Role of iron in neurotoxicity: a cause for concern in the elderly?
- (2008) James M Stankiewicz et al. CURRENT OPINION IN CLINICAL NUTRITION AND METABOLIC CARE
- Pharmacological evidence for a role of peroxynitrite in the pathophysiology of spinal cord injury
- (2008) Yiqin Xiong et al. EXPERIMENTAL NEUROLOGY
- Implication of the JNK pathway in a rat model of Huntington's disease
- (2008) V. Perrin et al. EXPERIMENTAL NEUROLOGY
- Emerging pathways in genetic Parkinson's disease: Potential role of ceramide metabolism in Lewy body disease
- (2008) Jose Bras et al. FEBS Journal
- 4-hydroxynonenal contributes to macrophage foam cell formation through increased expression of class A scavenger receptor at the level of translation
- (2008) Mi R. Yun et al. FREE RADICAL BIOLOGY AND MEDICINE
- Nrf2-induced antioxidant protection: A promising target to counteract ROS-mediated damage in neurodegenerative disease?
- (2008) Helga E. de Vries et al. FREE RADICAL BIOLOGY AND MEDICINE
- Antioxidant therapy in multiple sclerosis
- (2008) Abbas Mirshafiey et al. IMMUNOPHARMACOLOGY AND IMMUNOTOXICOLOGY
- Brain-derived neurotrophic factor and inflammatory markers in patients with early- vs. late-stage bipolar disorder
- (2008) Marcia Kauer-Sant'Anna et al. INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
- Oxidative stress markers in bipolar disorder: A meta-analysis
- (2008) Ana C. Andreazza et al. JOURNAL OF AFFECTIVE DISORDERS
- Identification of a Domain That Mediates Association of Platelet-activating Factor Acetylhydrolase with High Density Lipoprotein
- (2008) Alison A. Gardner et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Lysobisphosphatidic Acid Controls Endosomal Cholesterol Levels
- (2008) Julien Chevallier et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Electrophilic Cyclopentenone Neuroprostanes Are Anti-inflammatory Mediators Formed from the Peroxidation of the ω-3 Polyunsaturated Fatty Acid Docosahexaenoic Acid
- (2008) Erik S. Musiek et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Oxidative stress in NPC1 deficient cells: protective effect of allopregnanolone
- (2008) Stefania Zampieri et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Progesterone and its Metabolite Allopregnanolone Differentially Regulate Hemostatic Proteins after Traumatic Brain Injury
- (2008) Jacob W VanLandingham et al. JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM
- Selective decrease of bis(monoacylglycero)phosphate content in macrophages by high supplementation with docosahexaenoic acid
- (2008) Jérôme Bouvier et al. JOURNAL OF LIPID RESEARCH
- The emerging role of group VI calcium-independent phospholipase A2in releasing docosahexaenoic acid from brain phospholipids: Fig. 1.
- (2008) Joshua T. Green et al. JOURNAL OF LIPID RESEARCH
- The ketogenic diet increases mitochondrial glutathione levels
- (2008) Stuart G. Jarrett et al. JOURNAL OF NEUROCHEMISTRY
- Amyloid beta peptide and NMDA induce ROS from NADPH oxidase and AA release from cytosolic phospholipase A2in cortical neurons
- (2008) Phullara B. Shelat et al. JOURNAL OF NEUROCHEMISTRY
- Mutant copper-zinc superoxide dismutase associated with amyotrophic lateral sclerosis binds to adenine/uridine-rich stability elements in the vascular endothelial growth factor 3′-untranslated region
- (2008) Xuelin Li et al. JOURNAL OF NEUROCHEMISTRY
- Blockade of cytosolic phospholipase A2α prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses
- (2008) S MARUSIC et al. JOURNAL OF NEUROIMMUNOLOGY
- Neuroinflammatory response to lipopolysaccharide is exacerbated in mice genetically deficient in cyclooxygenase-2
- (2008) Saba Aid et al. Journal of Neuroinflammation
- Neuroaxonal Dystrophy Caused by Group VIA Phospholipase A2 Deficiency in Mice: A Model of Human Neurodegenerative Disease
- (2008) K. Shinzawa et al. JOURNAL OF NEUROSCIENCE
- The Effect of Darapladib on Plasma Lipoprotein-Associated Phospholipase A2 Activity and Cardiovascular Biomarkers in Patients With Stable Coronary Heart Disease or Coronary Heart Disease Risk Equivalent
- (2008) Emile R. Mohler et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Breaking the 3 h barrier for treatment of acute ischaemic stroke
- (2008) Geoffrey A Donnan et al. LANCET NEUROLOGY
- Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?
- (2008) J S Rao et al. MOLECULAR PSYCHIATRY
- Getting to the core of atherosclerosis
- (2008) Nancy R Webb NATURE MEDICINE
- Inhibition of lipoprotein-associated phospholipase A2 reduces complex coronary atherosclerotic plaque development
- (2008) Robert L Wilensky et al. NATURE MEDICINE
- Phospholipase A2 reduction ameliorates cognitive deficits in a mouse model of Alzheimer's disease
- (2008) Rene O Sanchez-Mejia et al. NATURE NEUROSCIENCE
- ALS-causing SOD1 mutants generate vascular changes prior to motor neuron degeneration
- (2008) Zhihui Zhong et al. NATURE NEUROSCIENCE
- Principles of bioactive lipid signalling: lessons from sphingolipids
- (2008) Yusuf A. Hannun et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Brain foods: the effects of nutrients on brain function
- (2008) Fernando Gómez-Pinilla NATURE REVIEWS NEUROSCIENCE
- Oxidative and Inflammatory Pathways in Parkinson’s Disease
- (2008) Rebecca L. Miller et al. NEUROCHEMICAL RESEARCH
- Mitochondrial Dysfunction and Psychiatric Disorders
- (2008) Gislaine T. Rezin et al. NEUROCHEMICAL RESEARCH
- Edaravone (MCI-186) Scavenges Reactive Oxygen Species and Ameliorates Tissue Damage in the Murine Spinal Cord Injury Model
- (2008) Takeshi AOYAMA et al. NEUROLOGIA MEDICO-CHIRURGICA
- Neuroprotective potential of phase II enzyme inducer diallyl trisulfide
- (2008) Meng-Meng Sun et al. NEUROLOGICAL RESEARCH
- Brain cholesterol metabolism and neurologic disease
- (2008) E. E. Benarroch NEUROLOGY
- Dyslipidemia is a protective factor in amyotrophic lateral sclerosis
- (2008) L. Dupuis et al. NEUROLOGY
- T2* and FSE MRI distinguishes four subtypes of neurodegeneration with brain iron accumulation
- (2008) A. McNeill et al. NEUROLOGY
- Neurodegeneration associated with genetic defects in phospholipase A2
- (2008) A. Gregory et al. NEUROLOGY
- Phenotypic spectrum of neurodegeneration associated with mutations in the PLA2G6 gene (PLAN)
- (2008) M. A. Kurian et al. NEUROLOGY
- Ethyl-Eicosapentaenoic Acid in First-Episode Psychosis. A 1H-MRS Study
- (2008) Gregor E Berger et al. NEUROPSYCHOPHARMACOLOGY
- Activation of Nrf2–ARE pathway in brain after traumatic brain injury
- (2008) Wei Yan et al. NEUROSCIENCE LETTERS
- Therapeutics for Alzheimer’s disease based on the metal hypothesis
- (2008) Ashley I. Bush et al. Neurotherapeutics
- Serine palmitoyltransferase inhibitor myriocin induces the regression of atherosclerotic plaques in hyperlipidemic ApoE-deficient mice
- (2008) T PARK et al. PHARMACOLOGICAL RESEARCH
- Disruption of Nrf2, a Key Inducer of Antioxidant Defenses, Attenuates ApoE-Mediated Atherosclerosis in Mice
- (2008) Thomas E. Sussan et al. PLoS One
- Tempol-mediated activation of latent iron regulatory protein activity prevents symptoms of neurodegenerative disease in IRP2 knockout mice
- (2008) M. C. Ghosh et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Elevated serum superoxide dismutase and thiobarbituric acid reactive substances in different phases of bipolar disorder and in schizophrenia
- (2008) Maurício Kunz et al. PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY
- Exploiting endogenous anti-apoptotic proteins for novel therapeutic strategies in cerebral ischemia
- (2008) A RAMI et al. PROGRESS IN NEUROBIOLOGY
- Increased oxidative stress as a mechanism for decreased BDNF levels in acute manic episodes
- (2008) Flávio Kapczinski et al. REVISTA BRASILEIRA DE PSIQUIATRIA
- Neurosteroids as modulators of neurogenesis and neuronal survival
- (2008) Ioannis Charalampopoulos et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- The influences of diet and exercise on mental health through hormesis
- (2007) Fernando Gomez-Pinilla AGEING RESEARCH REVIEWS
- Ceramide: A common pathway for atherosclerosis?
- (2007) Jean Bismuth et al. ATHEROSCLEROSIS
- Progesterone exerts neuroprotective effects after brain injury
- (2007) Donald G. Stein BRAIN RESEARCH REVIEWS
- Regenerative potential of allopregnanolone
- (2007) Jun Ming Wang et al. BRAIN RESEARCH REVIEWS
- Inflammation as a causative factor in the aetiology of Parkinson's disease
- (2007) P S Whitton BRITISH JOURNAL OF PHARMACOLOGY
- Integration of cytokine biology and lipid metabolism in stroke
- (2007) Rao Muralikrishna Adibhatla Frontiers in Bioscience-Landmark
- Aging of the brain, neurotrophin signaling, and Alzheimer's disease: Is IGF1-R the common culprit?
- (2007) Luigi Puglielli NEUROBIOLOGY OF AGING
- Lipidomics: Practical aspects and applications
- (2007) Claude Wolf et al. PROGRESS IN LIPID RESEARCH
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExplorePublish scientific posters with Peeref
Peeref publishes scientific posters from all research disciplines. Our Diamond Open Access policy means free access to content and no publication fees for authors.
Learn More