Methylglyoxal-Derived Advanced Glycation Endproducts in Multiple Sclerosis

Oxidative Stress Induced by Lipid Peroxidation Is Related with Inflammation of Demyelination and Neurodegeneration in Multiple Sclerosis

(2017) Pin Wang et al.   EUROPEAN NEUROLOGY

Reduced expression of membrane-bound (m)RAGE is a biomarker of multiple sclerosis disease progression

(2016) Zohara Sternberg et al.   IMMUNOBIOLOGY

Novel insights in the dysfunction of human blood-brain barrier after glycation

(2016) Maryam Hussain et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Microglial M1/M2 polarization and metabolic states

(2015) Ruben Orihuela et al.   BRITISH JOURNAL OF PHARMACOLOGY

Metabolic reprogramming in macrophages and dendritic cells in innate immunity

(2015) Beth Kelly et al.   CELL RESEARCH

The role of methylglyoxal and the glyoxalase system in diabetes and other age-related diseases

(2015) Dionne E.M. Maessen et al.   CLINICAL SCIENCE

Pathological mechanisms in progressive multiple sclerosis

(2015) Don H Mahad et al.   LANCET NEUROLOGY

Role of the innate and adaptive immune responses in the course of multiple sclerosis

(2015) Bernhard Hemmer et al.   LANCET NEUROLOGY

DHA Inhibited AGEs-Induced Retinal Microglia Activation Via Suppression of the PPARγ/NFκB Pathway and Reduction of Signal Transducers in the AGEs/RAGE Axis Recruitment into Lipid Rafts

(2015) Li Wang et al.   NEUROCHEMICAL RESEARCH

The role of immune cells, glia and neurons in white and gray matter pathology in multiple sclerosis

(2015) Giulia Mallucci et al.   PROGRESS IN NEUROBIOLOGY

Methylglyoxal, the dark side of glycolysis

(2015) Igor Allaman et al.   Frontiers in Neuroscience

Macrophage subsets and microglia in multiple sclerosis

(2014) Jeroen F. J. Bogie et al.   ACTA NEUROPATHOLOGICA

LR-90 prevents methylglyoxal-induced oxidative stress and apoptosis in human endothelial cells

(2014) James L. Figarola et al.   APOPTOSIS

Role of the Blood–Brain Barrier in Multiple Sclerosis

(2014) Genaro Gabriel Ortiz et al.   ARCHIVES OF MEDICAL RESEARCH

N ε -(Carboxymethyl)lysine-Receptor for Advanced Glycation End Product Axis Is a Key Modulator of Obesity-Induced Dysregulation of Adipokine Expression and Insulin Resistance

(2014) Katrien H.J. Gaens et al.   ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY

Molecular mechanisms linking neuroinflammation and neurodegeneration in MS

(2014) Erik Ellwardt et al.   EXPERIMENTAL NEUROLOGY

In acute experimental autoimmune encephalomyelitis, infiltrating macrophages are immune activated, whereas microglia remain immune suppressed

(2014) I. D. Vainchtein et al.   GLIA

Cellular distribution of glucose and monocarboxylate transporters in human brain white matter and multiple sclerosis lesions

(2014) Philip G. Nijland et al.   GLIA

Macrophages: A double-edged sword in experimental autoimmune encephalomyelitis

(2014) Zhilong Jiang et al.   IMMUNOLOGY LETTERS

Patients with multiple sclerosis show increased oxidative stress markers and somatic telomere length shortening

(2014) Jing-Zhi Guan et al.   MOLECULAR AND CELLULAR BIOCHEMISTRY

Oxidative Stress and Neurobiology of Demyelination

(2014) Srdjan Ljubisavljevic   MOLECULAR NEUROBIOLOGY

Glutathione in multiple sclerosis: More than just an antioxidant?

(2014) Andreia N Carvalho et al.   Multiple Sclerosis Journal

Role of advanced glycation end products in cellular signaling

(2014) Christiane Ott et al.   Redox Biology

Advanced glycation endproducts and its receptor for advanced glycation endproducts in obesity

(2013) Katrien HJ. Gaens et al.   CURRENT OPINION IN LIPIDOLOGY

The methylglyoxal-derived AGE tetrahydropyrimidine is increased in plasma of individuals with type 1 diabetes mellitus and in atherosclerotic lesions and is associated with sVCAM-1

(2013) M. G. A. van Eupen et al.   DIABETOLOGIA

Higher levels of advanced glycation endproducts in human carotid atherosclerotic plaques are associated with a rupture-prone phenotype

(2013) Nordin M.J. Hanssen et al.   EUROPEAN HEART JOURNAL

Advanced glycation endproducts in food and their effects on health

(2013) Malene W. Poulsen et al.   FOOD AND CHEMICAL TOXICOLOGY

Advanced glycoxidation and lipoxidation end products (AGEs and ALEs): an overview of their mechanisms of formation

(2013) G. Vistoli et al.   FREE RADICAL RESEARCH

Onset of secondary progressive phase and long-term evolution of multiple sclerosis

(2013) A. Scalfari et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Advanced glycation end-products disrupt the blood–brain barrier by stimulating the release of transforming growth factor–β by pericytes and vascular endothelial growth factor and matrix metalloproteinase–2 by endothelial cells in vitro

(2013) Fumitaka Shimizu et al.   NEUROBIOLOGY OF AGING

Glycolytic oligodendrocytes maintain myelin and long-term axonal integrity

(2012) Ursula Fünfschilling et al.   NATURE

AGEs–RAGE mediated up-regulation of connexin43 in activated human microglial CHME-5 cells

(2012) Shamim B. Shaikh et al.   NEUROCHEMISTRY INTERNATIONAL

Myelin-Derived Lipids Modulate Macrophage Activity by Liver X Receptor Activation

(2012) Jeroen F. J. Bogie et al.   PLoS One

Oral advanced glycation endproducts (AGEs) promote insulin resistance and diabetes by depleting the antioxidant defenses AGE receptor-1 and sirtuin 1

(2012) W. Cai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Brain Energy Metabolism: Focus on Astrocyte-Neuron Metabolic Cooperation

(2011) Mireille Bélanger et al.   Cell Metabolism

Advanced lipoxidation end-products

(2011) Reinald Pamplona   CHEMICO-BIOLOGICAL INTERACTIONS

Endogenous formation of Nε-(carboxymethyl)lysine is increased in fatty livers and induces inflammatory markers in an in vitro model of hepatic steatosis

(2011) Katrien H.J. Gaens et al.   JOURNAL OF HEPATOLOGY

Latitude is significantly associated with the prevalence of multiple sclerosis: a meta-analysis

(2011) S. Simpson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

A functional p.82G>S polymorphism in the RAGE gene is associated with multiple sclerosis in the Chinese population

(2011) Keshen Li et al.   Multiple Sclerosis Journal

Primary infection with the epstein-barr virus and risk of multiple sclerosis

(2010) Lynn I. Levin et al.   ANNALS OF NEUROLOGY

Radical changes in multiple sclerosis pathogenesis

(2010) Jack van Horssen et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

The RAGE Axis

(2010) Shi Fang Yan et al.   CIRCULATION RESEARCH

AGE-RAGE in Multiple Sclerosis Brain

(2010) Zohara Sternberg et al.   IMMUNOLOGICAL INVESTIGATIONS

Diagnostic potential of plasma carboxymethyllysine and carboxyethyllysine in multiple sclerosis

(2010) Zohara Sternberg et al.   Journal of Neuroinflammation

Lower levels of glutathione in the brains of secondary progressive multiple sclerosis patients measured by 1H magnetic resonance chemical shift imaging at 3 T

(2010) I-Y Choi et al.   Multiple Sclerosis Journal

RAGE Gene Polymorphisms in Patients with Multiple Sclerosis

(2009) Zoltán Tiszlavicz et al.   JOURNAL OF MOLECULAR NEUROSCIENCE

Virtual hypoxia and chronic necrosis of demyelinated axons in multiple sclerosis

(2009) Bruce D Trapp et al.   LANCET NEUROLOGY

MR spectroscopic imaging of glutathione in the white and gray matter at 7 T with an application to multiple sclerosis

(2009) Radhika Srinivasan et al.   MAGNETIC RESONANCE IMAGING

The bioenergetic and antioxidant status of neurons is controlled by continuous degradation of a key glycolytic enzyme by APC/C–Cdh1

(2009) Angel Herrero-Mendez et al.   NATURE CELL BIOLOGY

Tobacco smoking, but not Swedish snuff use, increases the risk of multiple sclerosis

(2009) A. K. Hedstrom et al.   NEUROLOGY

Astrocytes in multiple sclerosis: A product of their environment

(2008) A. Nair et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Severe oxidative damage in multiple sclerosis lesions coincides with enhanced antioxidant enzyme expression

(2008) J. van Horssen et al.   FREE RADICAL BIOLOGY AND MEDICINE

Pivotal Advance: HMGB1 expression in active lesions of human and experimental multiple sclerosis

(2008) Åsa Andersson et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Multiple sclerosis

(2008) Alastair Compston et al.   LANCET

Soluble receptor for advanced glycation end products in multiple sclerosis: A potential marker of disease severity

(2008) Z Sternberg et al.   Multiple Sclerosis Journal