The Role of Mitochondria in Reactive Oxygen Species Generation and Its Implications for Neurodegenerative Diseases

Characterization of the complete mitochondrial genome of Biston marginata (Lepidoptera: Geometridae) and phylogenetic analysis among lepidopteran insects

(2018) Nan Zheng et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Mitochondrial genome of Diaphania indica (saunders) (Lepidoptera: Pyraloidea) and implications for its phylogeny

(2018) Li-Shang Dai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Complete sequence and characterization of the Ectropis oblique mitochondrial genome and its phylogenetic implications

(2018) Li-Shang Dai et al.   INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES

Control of mitochondrial superoxide production by reverse electron transport at complex I

(2018) Ellen L. Robb et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Quality Control in Neurodegenerative Diseases: Focus on Parkinson's Disease and Huntington's Disease

(2018) Sandra Franco-Iborra et al.   Frontiers in Neuroscience

The cryo-electron microscopy structure of huntingtin

(2018) Qiang Guo et al.   NATURE

Redox-coupled quinone dynamics in the respiratory complex I

(2018) Judith Warnau et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The Sources of Reactive Oxygen Species and Its Possible Role in the Pathogenesis of Parkinson’s Disease

(2018) Minrui Weng et al.   Parkinsons Disease

The interplay between mitochondrial reactive oxygen species formation and the coenzyme Q reduction level

(2018) Karolina Dominiak et al.   Redox Biology

Huntington's disease: a clinical review

(2017) P. McColgan et al.   EUROPEAN JOURNAL OF NEUROLOGY

Reactive oxygen species production induced by pore opening in cardiac mitochondria: The role of complex III

(2017) Paavo Korge et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Huntington’s Disease and Mitochondria

(2017) Mohammad Jodeiri Farshbaf et al.   NEUROTOXICITY RESEARCH

Interactions of iron, dopamine and neuromelanin pathways in brain aging and Parkinson's disease

(2017) Fabio A. Zucca et al.   PROGRESS IN NEUROBIOLOGY

Electron tomographic analysis reveals ultrastructural features of mitochondrial cristae architecture which reflect energetic state and aging

(2017) Yi-fan Jiang et al.   Scientific Reports

Anti-Oxidants in Parkinson's Disease Therapy: A Critical Point of View

(2016) Roberta Filograna et al.   Current Neuropharmacology

The Role of Reactive Oxygen Species in the Pathogenesis of Alzheimer’s Disease, Parkinson’s Disease, and Huntington’s Disease: A Mini Review

(2016) Shanmugam Manoharan et al.   Oxidative Medicine and Cellular Longevity

Mitochondrial Cristae: Where Beauty Meets Functionality

(2016) Sara Cogliati et al.   TRENDS IN BIOCHEMICAL SCIENCES

Parkinson’s Disease: The Mitochondria-Iron Link

(2016) Yorka Muñoz et al.   Parkinsons Disease

Mitochondrial dysfunction in Parkinson’s disease

(2016) Qingsong Hu et al.   Translational Neurodegeneration

Characterization of the Complete Mitochondrial Genome of Leucoma salicis (Lepidoptera: Lymantriidae) and Comparison with Other Lepidopteran Insects

(2016) Yu-Xuan Sun et al.   Scientific Reports

Oxidative stress, mitochondrial dysfunction and neurodegenerative diseases; a mechanistic insight

(2015) Aashiq Hussain Bhat et al.   BIOMEDICINE & PHARMACOTHERAPY

Structure and function of mitochondrial membrane protein complexes

(2015) Werner Kühlbrandt   BMC BIOLOGY

Huntington disease iPSCs show early molecular changes in intracellular signaling, the expression of oxidative stress proteins and the p53 pathway

(2015) Wojciech J. Szlachcic et al.   Disease Models & Mechanisms

A Cellular Perspective on Brain Energy Metabolism and Functional Imaging

(2015) Pierre J. Magistretti et al.   NEURON

Huntington disease

(2015) Gillian P. Bates et al.   Nature Reviews Disease Primers

Aerobic Glycolysis in the Human Brain Is Associated with Development and Neotenous Gene Expression

(2014) Manu S. Goyal et al.   Cell Metabolism

The Role of Oxidative Stress in Huntington’s Disease: Are Antioxidants Good Therapeutic Candidates?

(2014) Joana Gil-Mohapel et al.   CURRENT DRUG TARGETS

The role of lipid peroxidation in neurological disorders

(2014) Mototada Shichiri   JOURNAL OF CLINICAL BIOCHEMISTRY AND NUTRITION

 -Synuclein Is Localized to Mitochondria-Associated ER Membranes

(2014) C. Guardia-Laguarta et al.   JOURNAL OF NEUROSCIENCE

Lipid Peroxidation: Production, Metabolism, and Signaling Mechanisms of Malondialdehyde and 4-Hydroxy-2-Nonenal

(2014) Antonio Ayala et al.   Oxidative Medicine and Cellular Longevity

HACE1 reduces oxidative stress and mutant Huntingtin toxicity by promoting the NRF2 response

(2014) B. Rotblat et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Complexity of dopamine metabolism

(2013) Johannes Meiser et al.   Cell Communication and Signaling

Mitochondria and Reactive Oxygen Species: Physiology and Pathophysiology

(2013) Subhashini Bolisetty et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial Biology and Parkinson's Disease

(2013) C. Perier et al.   Cold Spring Harbor Perspectives in Medicine

Clinical Approach to Parkinson's Disease: Features, Diagnosis, and Principles of Management

(2013) J. Massano et al.   Cold Spring Harbor Perspectives in Medicine

Iron toxicity in neurodegeneration

(2012) Marco T. Núñez et al.   BIOMETALS

Upregulated function of mitochondria-associated ER membranes in Alzheimer disease

(2012) Estela Area-Gomez et al.   EMBO JOURNAL

Reactive oxygen species are generated by the respiratory complex II - evidence for lack of contribution of the reverse electron flow in complex I

(2012) Rafael Moreno-Sánchez et al.   FEBS Journal

Glutathione redox cycle dysregulation in Huntington’s disease knock-in striatal cells

(2012) Márcio Ribeiro et al.   FREE RADICAL BIOLOGY AND MEDICINE

Dithiol-based Compounds Maintain Expression of Antioxidant Protein Peroxiredoxin 1 That Counteracts Toxicity of Mutant Huntingtin

(2012) Andrea Pitts et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mitochondrial Complex II Can Generate Reactive Oxygen Species at High Rates in Both the Forward and Reverse Reactions

(2012) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Iron accumulation in Parkinson’s disease

(2012) Hideki Mochizuki et al.   JOURNAL OF NEURAL TRANSMISSION

A mutation in sigma-1 receptor causes juvenile amyotrophic lateral sclerosis

(2011) Amr Al-Saif et al.   ANNALS OF NEUROLOGY

Antioxidants in Huntington's disease

(2011) Ashu Johri et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Dual Role of Mitofilin in Mitochondrial Membrane Organization and Protein Biogenesis

(2011) Karina von der Malsburg et al.   DEVELOPMENTAL CELL

Genomic instability induced by mutant succinate dehydrogenase subunit D (SDHD) is mediated by O2-• and H2O2

(2011) Kjerstin M. Owens et al.   FREE RADICAL BIOLOGY AND MEDICINE

Mutant huntingtin's interaction with mitochondrial protein Drp1 impairs mitochondrial biogenesis and causes defective axonal transport and synaptic degeneration in Huntington's disease

(2011) U. P. Shirendeb et al.   HUMAN MOLECULAR GENETICS

The Mechanism of Superoxide Production by the Antimycin-inhibited Mitochondrial Q-cycle

(2011) Casey L. Quinlan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Superoxide Is Produced by the Reduced Flavin in Mitochondrial Complex I

(2011) Kenneth R. Pryde et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evidence for Two Sites of Superoxide Production by Mitochondrial NADH-Ubiquinone Oxidoreductase (Complex I)

(2011) Jason R. Treberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A mitochondrial-focused genetic interaction map reveals a scaffold-like complex required for inner membrane organization in mitochondria

(2011) Suzanne Hoppins et al.   JOURNAL OF CELL BIOLOGY

Mitochondria: isolation, structure and function

(2011) Martin Picard et al.   JOURNAL OF PHYSIOLOGY-LONDON

Inhibitors of Succinate: Quinone Reductase/Complex II Regulate Production of Mitochondrial Reactive Oxygen Species and Protect Normal Cells from Ischemic Damage but Induce Specific Cancer Cell Death

(2011) Stephen J. Ralph et al.   PHARMACEUTICAL RESEARCH

Advances in metal-induced oxidative stress and human disease

(2011) Klaudia Jomova et al.   TOXICOLOGY

Modulation of lipid peroxidation and mitochondrial function improves neuropathology in Huntington’s disease mice

(2010) Junghee Lee et al.   ACTA NEUROPATHOLOGICA

Evidence of Oxidant Damage in Huntington's Disease: Translational Strategies Using Antioxidants

(2010) Edward C. Stack et al.   Annals of the New York Academy of Sciences

Oxidative Stress in Parkinson's Disease

(2010) Chun Zhou et al.   Annals of the New York Academy of Sciences

Discrimination between two possible reaction sequences that create potential risk of generation of deleterious radicals by cytochrome bc1

(2010) Marcin Sarewicz et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOENERGETICS

The sites and topology of mitochondrial superoxide production

(2010) Martin D. Brand   EXPERIMENTAL GERONTOLOGY

Oxidative stress and plasma aminopeptidase activity in Huntington’s disease

(2010) Raquel Duran et al.   JOURNAL OF NEURAL TRANSMISSION

Mitochondrial reactive oxygen species generation by the SDHC V69E mutation causes low birth weight and neonatal growth retardation

(2010) Takamasa Ishii et al.   MITOCHONDRION

Parkinson’s disease: oxidative stress and therapeutic approaches

(2010) Sankar Surendran et al.   NEUROLOGICAL SCIENCES

Stoichiometry of Base Excision Repair Proteins Correlates with Increased Somatic CAG Instability in Striatum over Cerebellum in Huntington's Disease Transgenic Mice

(2009) Agathi-Vassiliki Goula et al.   PLoS Genetics

Movement of the Iron−Sulfur Head Domain of Cytochromebc1Transiently Opens the Catalytic QoSite for Reaction with Oxygen†

(2008) Arkadiusz Borek et al.   BIOCHEMISTRY

Oxidative and nitrative protein modifications in Parkinson's disease

(2008) Steven R. Danielson et al.   FREE RADICAL BIOLOGY AND MEDICINE

Stigmatellin Induces Reduction of Iron-Sulfur Protein in the Oxidized Cytochromebc1Complex

(2008) Buddha Gurung et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The Mechanism of Mitochondrial Superoxide Production by the Cytochromebc1Complex

(2008) Stefan Dröse et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Environmental-induced oxidative stress in neurodegenerative disorders and aging

(2008) Lucia Migliore et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Increased oxidative damage in peripheral blood correlates with severity of Parkinson's disease

(2008) Chiung-Mei Chen et al.   NEUROBIOLOGY OF DISEASE

Mitochondria in Neuroplasticity and Neurological Disorders

(2008) Mark P. Mattson et al.   NEURON

Structure of the human voltage-dependent anion channel

(2008) M. Bayrhuber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mitochondrial Pathophysiology, Reactive Oxygen Species, and Cardiovascular Diseases

(2008) Ling Gao et al.   VETERINARY CLINICS OF NORTH AMERICA-SMALL ANIMAL PRACTICE

Ischemic defects in the electron transport chain increase the production of reactive oxygen species from isolated rat heart mitochondria

(2007) Qun Chen et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

Complex I deficiency in Parkinson's disease frontal cortex

(2007) W. Davis Parker et al.   BRAIN RESEARCH

Oxidative Stress and Neurotoxicity

(2007) Lawrence M. Sayre et al.   CHEMICAL RESEARCH IN TOXICOLOGY

ΔΨm-Dependent and -independent production of reactive oxygen species by rat brain mitochondria

(2003) Tatyana V. Votyakova et al.   JOURNAL OF NEUROCHEMISTRY