Oxidative Stress, Antioxidant Capabilities, and Bioavailability: Ellagic Acid or Urolithins?

Polyester-Based Dendrimer Nanoparticles Combined with Etoposide Have an Improved Cytotoxic and Pro-Oxidant Effect on Human Neuroblastoma Cells

(2020) Silvana Alfei et al.   Antioxidants

The Metabolite Urolithin-A Ameliorates Oxidative Stress in Neuro-2a Cells, Becoming a Potential Neuroprotective Agent

(2020) Guillermo Cásedas et al.   Antioxidants

Neuroinflammation in Aged Brain: Impact of the Oral Administration of Ellagic Acid Microdispersion

(2020) Raffaella Boggia et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Formulation Strategies to Improve Oral Bioavailability of Ellagic Acid

(2020) Guendalina Zuccari et al.   Applied Sciences-Basel

Pomegranate and grape by-products and their active compounds: Are they a valuable source for food applications?

(2019) Mariana A. Andrade et al.   TRENDS IN FOOD SCIENCE & TECHNOLOGY

Ellagic acid a multi-target bioactive compound for drug discovery in CNS? A narrative review

(2019) Silvana Alfei et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Establishment of pressurized-liquid extraction by response surface methodology approach coupled to HPLC-DAD-TOF-MS for the determination of phenolic compounds of myrtle leaves

(2018) Elixabet Díaz-de-Cerio et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Aqueous extracts of two tropical ethnobotanicals ( Tetrapleura tetraptera and Q uassia undulata) improved spatial and non-spatial working memories in scopolamine-induced amnesic rats: Influence of neuronal cholinergic and antioxidant systems

(2018) Veronica O. Odubanjo et al.   BIOMEDICINE & PHARMACOTHERAPY

Three new flavonoids, proanthocyanidin, and accompanying phenolic constituents from Feijoa sellowiana

(2018) Hiroe Aoyama et al.   BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY

Crude extract and fractions from Eugenia uniflora Linn leaves showed anti-inflammatory, antioxidant, and antibacterial activities

(2018) Tamires Rocha Falcão et al.   BMC Complementary and Alternative Medicine

Chemical characterization of Myrciaria floribunda (H. West ex Willd) fruit

(2018) Luciana Mouta de Oliveira et al.   FOOD CHEMISTRY

Flavonols and ellagic acid derivatives in peels of different species of jabuticaba ( Plinia spp.) identified by HPLC-DAD-ESI/MS n

(2018) Nathália de Andrade Neves et al.   FOOD CHEMISTRY

Nutritional potential, chemical profile and antioxidant activity of Chichá ( Sterculia striata ) nuts and its by-products

(2018) Priscila de Britto Policarpi et al.   FOOD RESEARCH INTERNATIONAL

Identification and Characterization of Phenolic Compounds in Black Walnut Kernels

(2018) Danh C. Vu et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ellagic acid mitigates arsenic-trioxide-induced mitochondrial dysfunction and cytotoxicity in SH-SY5Y cells

(2018) Fakiha Firdaus et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Ethnopharmacology, phytochemistry, and pharmacology of Cornus officinalis Sieb. et Zucc

(2018) Jun Huang et al.   JOURNAL OF ETHNOPHARMACOLOGY

Chemical characterization and cytotoxic, genotoxic, and mutagenic properties of Baccharis trinervis (Lam, Persoon) from Colombia and Brazil

(2018) Victoria Jaramillo-García et al.   JOURNAL OF ETHNOPHARMACOLOGY

Lafoensia pacari A. St.-Hil.: Wound healing activity and mechanism of action of standardized hydroethanolic leaves extract

(2018) Lucas Olivo Martins Pereira et al.   JOURNAL OF ETHNOPHARMACOLOGY

LC–MS analysis and cytoprotective effect against the mercurium and aluminium toxicity by bioactive products of Psidium brownianum Mart. ex DC

(2018) Celestina E. Sobral-Souza et al.   JOURNAL OF HAZARDOUS MATERIALS

Chemical constituents from Canarium album Raeusch and their anti-influenza A virus activities

(2018) Luo-Ping Yang et al.   Journal of Natural Medicines

Weed Suppressing Potential and Isolation of Potent Plant Growth Inhibitors from Castanea crenata Sieb. et Zucc

(2018) Phung Tuyen et al.   MOLECULES

Chemical constituents of Geum urbanum L. roots

(2018) Quang Ton That et al.   NATURAL PRODUCT RESEARCH

A new flavone glucoside together with known ellagitannins and flavones with anti-diabetic and anti-obesity activities from the flowers of pomegranate (Punica granatum)

(2018) Sheng Wu et al.   NATURAL PRODUCT RESEARCH

Terminalia chebula supplementation attenuates cisplatin-induced nephrotoxicity in Wistar rats through modulation of apoptotic pathway

(2018) Prerna Kalra et al.   NATURAL PRODUCT RESEARCH

Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

(2018) Xiaocong Pang et al.   Oxidative Medicine and Cellular Longevity

The effects of urolithins on the response of prostate cancer cells to non-steroidal antiandrogen bicalutamide

(2018) Iwona J. Stanisławska et al.   PHYTOMEDICINE

A Pharmacological Update of Ellagic Acid

(2018) José-Luis Ríos et al.   PLANTA MEDICA

Identification of Ellagic Acid from Plant Rhodiola rosea L. as an Anti-Ebola Virus Entry Inhibitor

(2018) Qinghua Cui et al.   Viruses-Basel

Metabolic fate of strawberry polyphenols after chronic intake in healthy older adults

(2018) Amandeep K. Sandhu et al.   Food & Function

The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging

(2018) A. Cortés-Martín et al.   Food & Function

Polyphenols-rich extract from Pleurotus eryngii with growth inhibitory of HCT116 colon cancer cells and anti-inflammatory function in RAW264.7 cells

(2018) Qiuhui Hu et al.   Food & Function

Phytochemicals from Camellia nitidissima Chi Flowers Reduce the Pyocyanin Production and Motility of Pseudomonas aeruginosa PAO1

(2018) Rui Yang et al.   Frontiers in Microbiology

Oxidative stress, aging, and diseases

(2018) Ilaria Liguori et al.   Clinical Interventions in Aging

Berry Phenolic Antioxidants – Implications for Human Health?

(2018) Beata Olas   Frontiers in Pharmacology

Oxidative Stress: A Major Player in Cerebrovascular Alterations Associated to Neurodegenerative Events

(2018) Cristina Carvalho et al.   Frontiers in Physiology

Polyphenolic profile and antioxidant activities of Madeiran elderberry ( Sambucus lanceolata ) as affected by simulated in vitro digestion

(2017) Joana Pinto et al.   FOOD RESEARCH INTERNATIONAL

Multiple effects of ellagic acid on human colorectal carcinoma cells identified by gene expression profile analysis

(2017) Jinlu Zhao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Ellagitannins from Strawberries with Different Degrees of Polymerization Showed Different Metabolism through Gastrointestinal Tract of Rats

(2017) Joanna Milala et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Jabuticaba (Myrciaria jaboticaba) juice obtained by steam-extraction: phenolic compound profile, antioxidant capacity, microbiological stability, and sensory acceptability

(2017) Kim Ohanna Pimenta Inada et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Phytochemical composition, antioxidant and anti-bacterial activity of Syzygium calophyllifolium Walp. fruit

(2017) Saikumar Sathyanarayanan et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Antidiabetic and antioxidant functionality associated with phenolic constituents from fruit parts of indigenous black jamun (Syzygium cumini L.) landraces

(2017) H. P. Gajera et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Determination of anthocyanins and non-anthocyanin polyphenols by ultra performance liquid chromatography/electrospray ionization mass spectrometry (UPLC/ESI–MS) in jussara (Euterpe edulis) extracts

(2017) Gláucia S. Vieira et al.   JOURNAL OF FOOD SCIENCE AND TECHNOLOGY-MYSORE

Sea Buckthorn (Hippophae rhamnoides L.) Leaf Extracts Protect Neuronal PC-12 Cells from Oxidative Stress

(2017) Chi Heung Cho et al.   JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY

Ellagic acid glycosides with hepatoprotective activity from traditional Tibetan medicine Potentilla anserina

(2017) Toshio Morikawa et al.   Journal of Natural Medicines

Antioxidant potential assessment of phenolic and flavonoid rich fractions of Clematis orientalis and Clematis ispahanica (Ranunculaceae)

(2017) Ehsan Karimi et al.   NATURAL PRODUCT RESEARCH

Ellagic Acid Enhances Apoptotic Sensitivity of Breast Cancer Cells to γ-Radiation

(2017) Vidhula Ahire et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Bioactivity-guided isolation and identification of anti-adipogenic compounds from Sanguisorba officinalis

(2017) Sun Hyuk Im et al.   PHARMACEUTICAL BIOLOGY

In vitro antioxidant and antiproliferative activities of various solvent fractions from Clerodendrum viscosum leaves

(2017) Nripendranath Mandal et al.   Pharmacognosy Magazine

Polyphenols from Euphorbia pekinensis Inhibit AGEs Formation In Vitro and Vessel Dilation in Larval Zebrafish In Vivo

(2017) Ik-Soo Lee et al.   PLANTA MEDICA

Polyphenolic content, in vitro antioxidant activity and chemical composition of extract from Nephelium lappaceum L. (Mexican rambutan) husk

(2017) Cristian Hernández et al.   Asian Pacific Journal of Tropical Medicine

Ellagic acid inhibits the proliferation of human pancreatic carcinoma PANC-1 cells in vitro and in vivo

(2017) Hao Cheng et al.   Oncotarget

Leaf and Root Extracts from Campomanesia adamantium (Myrtaceae) Promote Apoptotic Death of Leukemic Cells via Activation of Intracellular Calcium and Caspase-3

(2017) Jaqueline F. Campos et al.   Frontiers in Pharmacology

Inhibition of protein glycation, antioxidant and antiproliferative activities of Carpobrotus edulis extracts

(2016) Jawhar Hafsa et al.   BIOMEDICINE & PHARMACOTHERAPY

Proanthocyanidins and hydrolysable tannins: occurrence, dietary intake and pharmacological effects

(2016) Antonella Smeriglio et al.   BRITISH JOURNAL OF PHARMACOLOGY

Insights Into Effects of Ellagic Acid on the Nervous System: A Mini Review

(2016) Touqeer Ahmed et al.   CURRENT PHARMACEUTICAL DESIGN

Evaluation of different extraction methods from pomegranate whole fruit or peels and the antioxidant and antiproliferative activity of the polyphenolic fraction

(2016) Alessandra Masci et al.   FOOD CHEMISTRY

Organic acids in Kakadu plum ( Terminalia ferdinandiana ): The good (ellagic), the bad (oxalic) and the uncertain (ascorbic)

(2016) David J. Williams et al.   FOOD RESEARCH INTERNATIONAL

Advanced glycation end products and their receptor in age-related, non-communicable chronic inflammatory diseases; Overview of clinical evidence and potential contributions to disease

(2016) Niki L. Reynaert et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

Coumarin–Chalcone Hybrids as Peroxyl Radical Scavengers: Kinetics and Mechanisms

(2016) Gloria Mazzone et al.   Journal of Chemical Information and Modeling

Differences in Metabolism of Ellagitannins by Human Gut Microbiota ex Vivo Cultures

(2016) Jakub P. Piwowarski et al.   JOURNAL OF NATURAL PRODUCTS

Urolithins, the rescue of “old” metabolites to understand a “new” concept: Metabotypes as a nexus among phenolic metabolism, microbiota dysbiosis, and host health status

(2016) Francisco A. Tomás-Barberán et al.   MOLECULAR NUTRITION & FOOD RESEARCH

The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions

(2016) Marcos Roberto de Oliveira   NEUROCHEMICAL RESEARCH

Redox Homeostasis and Cellular Antioxidant Systems: Crucial Players in Cancer Growth and Therapy

(2016) Barbara Marengo et al.   Oxidative Medicine and Cellular Longevity

Polyphenols as Modulator of Oxidative Stress in Cancer Disease: New Therapeutic Strategies

(2016) Anna Maria Mileo et al.   Oxidative Medicine and Cellular Longevity

Prooxidant Activity of Polyphenols, Flavonoids, Anthocyanins and Carotenoids: Updated Review of Mechanisms and Catalyzing Metals

(2016) Samira Eghbaliferiz et al.   PHYTOTHERAPY RESEARCH

Food Antioxidants: Chemical Insights at the Molecular Level

(2016) Annia Galano et al.   Annual Review of Food Science and Technology

Investigation of the profile of phenolic compounds in the leaves and stems of Pandiaka heudelotii using gas chromatography coupled with flame ionization detector

(2016) Mercy O. Ifeanacho et al.   Food Science & Nutrition

Nutritive value and polyphenol content of pomegranate seed pulp ensiled with different tannin-inactivating agents

(2015) F. Khosravi et al.   ANIMAL FEED SCIENCE AND TECHNOLOGY

Clinical Relevance of Biomarkers of Oxidative Stress

(2015) Jeroen Frijhoff et al.   ANTIOXIDANTS & REDOX SIGNALING

Reactive nitrogen species in cellular signaling

(2015) Levi Adams et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Pomegranate peel and peel extracts: Chemistry and food features

(2015) Saeed Akhtar et al.   FOOD CHEMISTRY

N-Acetylserotonin and 6-Hydroxymelatonin against Oxidative Stress: Implications for the Overall Protection Exerted by Melatonin

(2015) Ruslán Álvarez-Diduk et al.   JOURNAL OF PHYSICAL CHEMISTRY B

Comprehensive characterization of the effects of ellagic acid and urolithins on colorectal cancer and key-associated molecular hallmarks: MicroRNA cell specific induction ofCDKN1A(p21) as a common mechanism involved

(2015) Antonio González-Sarrías et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Reactive Oxygen and Nitrogen Species

(2015) Dereck Salisbury et al.   NURSING RESEARCH

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

(2015) Wylly Ramsés García-Niño et al.   PHARMACOLOGICAL RESEARCH

Quercetin 7-O-glucoside suppresses nitrite-induced formation of dinitrosocatechins and their quinones in catechin/nitrite systems under stomach simulating conditions

(2015) Filis Morina et al.   Food & Function

Ellagic Acid: An Unusually Versatile Protector against Oxidative Stress

(2014) Annia Galano et al.   CHEMICAL RESEARCH IN TOXICOLOGY

Oxidized low-density lipoprotein as a biomarker of cardiovascular diseases

(2014) Andreja Trpkovic et al.   CRITICAL REVIEWS IN CLINICAL LABORATORY SCIENCES

Metabolic Fate of Ellagitannins: Implications for Health, and Research Perspectives for Innovative Functional Foods

(2014) Cristina Garcia-Muñoz et al.   CRITICAL REVIEWS IN FOOD SCIENCE AND NUTRITION

Profiling ellagic acid content: The importance of form and ascorbic acid levels

(2014) David J. Williams et al.   FOOD RESEARCH INTERNATIONAL

Gordonibacter urolithinfaciens sp. nov., a urolithin-producing bacterium isolated from the human gut

(2014) M. V. Selma et al.   INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY

Ellagic Acid Metabolism by Human Gut Microbiota: Consistent Observation of Three Urolithin Phenotypes in Intervention Trials, Independent of Food Source, Age, and Health Status

(2014) Francisco A. Tomás-Barberán et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Endocrine Disruptome—An Open Source Prediction Tool for Assessing Endocrine Disruption Potential through Nuclear Receptor Binding

(2014) Katra Kolšek et al.   Journal of Chemical Information and Modeling

Melatonin and its metabolites as copper chelating agents and their role in inhibiting oxidative stress: a physicochemical analysis

(2014) Annia Galano et al.   JOURNAL OF PINEAL RESEARCH

Targeted metabolic profiling of pomegranate polyphenols and urolithins in plasma, urine and colon tissues from colorectal cancer patients

(2014) María A. Nuñez-Sánchez et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Description of urolithin production capacity from ellagic acid of two human intestinal Gordonibacter species

(2014) María V. Selma et al.   Food & Function

Oxidative Stress, Prooxidants, and Antioxidants: The Interplay

(2014) Anu Rahal et al.   Biomed Research International

Phytochemical divergence in 45 accessions of Terminalia ferdinandiana (Kakadu plum)

(2013) Izabela Konczak et al.   FOOD CHEMISTRY

Diversity of urinary excretion patterns of main ellagitannins' colonic metabolites after ingestion of tropical highland blackberry (Rubus adenotrichus) juice

(2013) Cristina García-Muñoz et al.   FOOD RESEARCH INTERNATIONAL

Oxidative Stress in Aging-Matters of the Heart and Mind

(2013) Krishnan Venkataraman et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Urolithins Display both Antioxidant and Pro-oxidant Activities Depending on Assay System and Conditions

(2013) Tuija Kallio et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Markers of oxidant stress that are clinically relevant in aging and age-related disease

(2013) Kimberly D. Jacob et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Role of Glutathione in Cancer Progression and Chemoresistance

(2013) Nicola Traverso et al.   Oxidative Medicine and Cellular Longevity

Effects of Ellagic Acid on Angiogenic Factors in Prostate Cancer Cells

(2013) Luca Vanella et al.   Cancers

Ellagic acid protects human keratinocyte (HaCaT) cells against UVA-induced oxidative stress and apoptosis through the upregulation of the HO-1 and Nrf-2 antioxidant genes

(2012) You-Cheng Hseu et al.   FOOD AND CHEMICAL TOXICOLOGY

Ellagitannins, ellagic acid and their derived metabolites: A review about source, metabolism, functions and health

(2011) J.M. Landete   FOOD RESEARCH INTERNATIONAL

UV and MS Identification of Urolithins and Nasutins, the Bioavailable Metabolites of Ellagitannins and Ellagic Acid in Different Mammals

(2011) Rocío González-Barrio et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Synthesis, Characterization, and Evaluation of Radical Scavenging Ability of Ellagic Acid-Loaded Nanogels

(2011) Gautam Behl et al.   Journal of Nanomaterials

Pressurised water extraction of polyphenols from pomegranate peels

(2010) Mustafa Çam et al.   FOOD CHEMISTRY

Role of Reactive Oxygen Species in the Progression of Type 2 Diabetes and Atherosclerosis

(2010) Hideaki Kaneto et al.   MEDIATORS OF INFLAMMATION

Ellagitannins, ellagic acid and vascular health

(2010) Mar Larrosa et al.   MOLECULAR ASPECTS OF MEDICINE

Polyphenolic compounds in the fruits of Egyptian medicinal plants (Terminalia bellerica, Terminalia chebula and Terminalia horrida): Characterization, quantitation and determination of antioxidant capacities

(2010) Beate Pfundstein et al.   PHYTOCHEMISTRY

A Systematic Review of the Evidence Supporting a Causal Link Between Dietary Factors and Coronary Heart Disease

(2009) Andrew Mente et al.   ARCHIVES OF INTERNAL MEDICINE

Paraoxonase 1 (PON1) expression in hepatocytes is upregulated by pomegranate polyphenols: A role for PPAR-γ pathway

(2009) Jasmin Khateeb et al.   ATHEROSCLEROSIS

Coffee and Green Tea As a Large Source of Antioxidant Polyphenols in the Japanese Population

(2009) Yoichi Fukushima et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Anti-inflammatory properties of a pomegranate extract and its metabolite urolithin-A in a colitis rat model and the effect of colon inflammation on phenolic metabolism☆

(2009) Mar Larrosa et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Tannins: Current knowledge of food sources, intake, bioavailability and biological effects

(2009) José Serrano et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Phenolics: From Chemistry to Biology

(2009) David Pereira et al.   MOLECULES

Anti-Ischemic Activity and Endothelium-Dependent Vasorelaxant Effect of Hydrolysable Tannins from the Leaves ofRhus coriaria(Sumac) in Isolated Rabbit Heart and Thoracic Aorta

(2009) Giangiacomo Beretta et al.   PLANTA MEDICA

Interactions of gallic acid, resveratrol, quercetin and aspirin at the platelet cyclooxygenase-1 level Functional and modelling studies

(2009) Marilena Crescente et al.   THROMBOSIS AND HAEMOSTASIS

Multitargeted therapy of cancer by ellagitannins

(2008) David Heber   CANCER LETTERS

Ellagic acid: Characterization as substrate of polyphenol oxidase

(2008) Jose Luis Muñoz-Muñoz et al.   IUBMB LIFE