The Effects of Ellagic Acid upon Brain Cells: A Mechanistic View and Future Directions

Altered sensitivity to ellagic acid in neuroblastoma cells undergoing differentiation with 12- O -tetradecanoylphorbol-13-acetate and all- trans retinoic acid

(2015) Christina Fjæraa Alfredsson et al.   BIOMEDICINE & PHARMACOTHERAPY

Efficacy and Safety of Pomegranate Medicinal Products for Cancer

(2015) Christian Vlachojannis et al.   Evidence-based Complementary and Alternative Medicine

Ellagic acid prevents cognitive and hippocampal long-term potentiation deficits and brain inflammation in rat with traumatic brain injury

(2015) Yaghoob Farbood et al.   LIFE SCIENCES

Involvement of the Nrf2/HO-1 signaling pathway in sulfuretin-induced protection against amyloid beta25–35 neurotoxicity

(2015) S.-H. Kwon et al.   NEUROSCIENCE

Long-term (15 mo) dietary supplementation with pomegranates from Oman attenuates cognitive and behavioral deficits in a transgenic mice model of Alzheimer's disease

(2015) Selvaraju Subash et al.   NUTRITION

Ellagic acid: Pharmacological activities and molecular mechanisms involved in liver protection

(2015) Wylly Ramsés García-Niño et al.   PHARMACOLOGICAL RESEARCH

Ellagic acid, a polyphenolic compound, selectively induces ROS-mediated apoptosis in cancerous B-lymphocytes of CLL patients by directly targeting mitochondria

(2015) Ahmad Salimi et al.   Redox Biology

Long-Term Dietary Supplementation of Pomegranates, Figs and Dates Alleviate Neuroinflammation in a Transgenic Mouse Model of Alzheimer’s Disease

(2015) Musthafa Mohamed Essa et al.   PLoS One

Ellagic Acid Mitigates SNO-PDI Induced Aggregation of Parkinsonian Biomarkers

(2014) Parijat Kabiraj et al.   ACS Chemical Neuroscience

Ellagic acid, an NF-κB inhibitor, ameliorates renal function in experimental diabetic nephropathy

(2014) Amjid Ahad et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Protective Effect of Ellagic Acid on Concanavalin A-Induced Hepatitis via Toll-Like Receptor and Mitogen-Activated Protein Kinase/Nuclear Factor κB Signaling Pathways

(2014) Jae Hong Lee et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Ellagic Acid Antiinflammatory and Antiapoptotic Potential Mediate Renoprotection in Cisplatin Nephrotoxic Rats

(2014) Amany M. El-Garhy et al.   JOURNAL OF BIOCHEMICAL AND MOLECULAR TOXICOLOGY

Pomegranate extract protects against cerebral ischemia/reperfusion injury and preserves brain DNA integrity in rats

(2014) Maha A.E. Ahmed et al.   LIFE SCIENCES

Protective effect of ellagic acid against TCDD-induced renal oxidative stress: Modulation of CYP1A1 activity and antioxidant defense mechanisms

(2014) Viswanadha Vijaya Padma et al.   MOLECULAR BIOLOGY REPORTS

Method Development and Validation for Pharmacokinetic and Tissue Distributions of Ellagic Acid Using Ultrahigh Performance Liquid Chromatography-Tandem Mass Spectrometry (UPLC-MS/MS)

(2014) Linlin Yan et al.   MOLECULES

Ellagic Acid Induces Novel and Atypical PKC Isoforms and Promotes Caspase-3 Dependent Apoptosis by Blocking Energy Metabolism

(2014) Sudha Mishra et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Metabolic control of cell death

(2014) D. R. Green et al.   SCIENCE

Inhibition of allergic airway inflammation through the blockage of NF-κB activation by ellagic acid in an ovalbumin-induced mouse asthma model

(2014) Ershun Zhou et al.   Food & Function

Ellagic acid-induced thrombotic focal cerebral ischemic model in rats

(2014) Xiaoming Pang et al.   JOURNAL OF PHARMACOLOGICAL AND TOXICOLOGICAL METHODS

Punicalagin and Ellagic Acid Demonstrate Antimutagenic Activity and Inhibition of Benzo[a]pyrene Induced DNA Adducts

(2014) Maryam Zahin et al.   Biomed Research International

Ellagic acid induces a dose- and time-dependent depolarization of mitochondria and activation of caspase-9 and -3 in human neuroblastoma cells

(2013) Christina Fjæraa Alfredsson et al.   BIOMEDICINE & PHARMACOTHERAPY

Ellagic acid encapsulated chitosan nanoparticles for drug delivery system in human oral cancer cell line (KB)

(2013) V. Arulmozhi et al.   COLLOIDS AND SURFACES B-BIOINTERFACES

Effects of Nicorandil in Neuroprotective Activation of PI3K/AKT Pathways in a Cellular Model of Alzheimer's Disease

(2013) Jingjing Kong et al.   EUROPEAN NEUROLOGY

Pomegranate Juice Augments Memory and fMRI Activity in Middle-Aged and Older Adults with Mild Memory Complaints

(2013) Susan Y. Bookheimer et al.   Evidence-based Complementary and Alternative Medicine

Ellagic acid attenuates bleomycin and cyclophosphamide-induced pulmonary toxicity in Wistar rats

(2013) Saba et al.   FOOD AND CHEMICAL TOXICOLOGY

Pomegranate Polyphenols and Extract Inhibit Nuclear Factor of Activated T-Cell Activity and Microglial Activation In Vitro and in a Transgenic Mouse Model of Alzheimer Disease

(2013) Lalida Rojanathammanee et al.   JOURNAL OF NUTRITION

Pomegranate and type 2 diabetes

(2013) Saleem Banihani et al.   NUTRITION RESEARCH

Neuroprotective Effects of a Variety of Pomegranate Juice Extracts against MPTP-Induced Cytotoxicity and Oxidative Stress in Human Primary Neurons

(2013) Nady Braidy et al.   Oxidative Medicine and Cellular Longevity

Undifferentiated and Differentiated PC12 Cells Protected by Huprines Against Injury Induced by Hydrogen Peroxide

(2013) Marta Pera et al.   PLoS One

Evaluation of the effects of ellagic acid (EA) on 7,12-dimethylbenz(α) anthracene (DMBA) induced micronuclei in mammalian cells in vitro and in vivo

(2013) Maria Rosaria Grossi et al.   TOXICOLOGY LETTERS

Resveratrol affects undifferentiated and differentiated PC12 cells differently, particularly with respect to possible differences in mitochondrial and autophagic functions

(2012) Naoya Hayakawa et al.   EUROPEAN JOURNAL OF CELL BIOLOGY

Dietary supplementation of an ellagic acid-enriched pomegranate extract attenuates chronic colonic inflammation in rats

(2012) Maria Angeles Rosillo et al.   PHARMACOLOGICAL RESEARCH

The protective role of pomegranate juice against carbon tetrachloride–induced oxidative stress in rats

(2012) Mihdiye Pirinççioğlu et al.   TOXICOLOGY AND INDUSTRIAL HEALTH

Ellagic acid coordinately attenuates Wnt/β-catenin and NF-κB signaling pathways to induce intrinsic apoptosis in an animal model of oral oncogenesis

(2011) Prabukumar Anitha et al.   EUROPEAN JOURNAL OF NUTRITION

Differentiation of SH-SY5Y cells to a neuronal phenotype changes cellular bioenergetics and the response to oxidative stress

(2011) Lonnie Schneider et al.   FREE RADICAL BIOLOGY AND MEDICINE

AMP-activated protein kinase inhibits NF-κB signaling and inflammation: impact on healthspan and lifespan

(2011) Antero Salminen et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Ellagic acid attenuates oxidative stress on brain and sciatic nerve and improves histopathology of brain in streptozotocin-induced diabetic rats

(2011) Ertugrul Uzar et al.   NEUROLOGICAL SCIENCES

Influence of ellagic acid on prostate cancer cell proliferation: A caspase–dependent pathway

(2011) Arshi Malik et al.   Asian Pacific Journal of Tropical Medicine

A chitosan/β-glycerophosphate thermo-sensitive gel for the delivery of ellagic acid for the treatment of brain cancer

(2010) Sungwoo Kim et al.   BIOMATERIALS

Comparison between proliferative and neuron-like SH-SY5Y cells as an in vitro model for Parkinson disease studies

(2010) Fernanda Martins Lopes et al.   BRAIN RESEARCH

Ellagic acid, a natural polyphenolic compound, induces apoptosis and potentiates retinoic acid-induced differentiation of human leukemia HL-60 cells

(2010) Yuki Hagiwara et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Ellagic acid inhibits oxidized LDL-mediated LOX-1 expression, ROS generation, and inflammation in human endothelial cells

(2010) Wen-Jane Lee et al.   JOURNAL OF VASCULAR SURGERY

Determinants of paraoxonase activity in healthy adults

(2010) Christine Boesch-Saadatmandi et al.   MOLECULAR NUTRITION & FOOD RESEARCH

Ellagic acid protects endothelial cells from oxidized low-density lipoprotein-induced apoptosis by modulating the PI3K/Akt/eNOS pathway

(2010) Hsiu-Chung Ou et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Ellagic acid promotes Aβ42 fibrillization and inhibits Aβ42-induced neurotoxicity

(2009) Ying Feng et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

The inhibition of glioma growth in vitro and in vivo by a chitosan/ellagic acid composite biomaterial

(2009) Sungwoo Kim et al.   BIOMATERIALS

Ellagic acid protects hepatocytes from damage by inhibiting mitochondrial production of reactive oxygen species

(2009) Jung Me Hwang et al.   BIOMEDICINE & PHARMACOTHERAPY

High-Throughput Cell-Based Screen for Chemicals That Inhibit Infection by Simian Virus 40 and Human Polyomaviruses

(2009) E. C. Goodwin et al.   JOURNAL OF VIROLOGY

Effect of ellagic acid on proliferation, cell adhesion and apoptosis in SH-SY5Y human neuroblastoma cells

(2008) Christina Fjaeraa et al.   BIOMEDICINE & PHARMACOTHERAPY

Hepatoprotective role and antioxidant capacity of pomegranate (Punica granatum) flowers infusion against trichloroacetic acid-exposed in rats

(2008) Ismail Celik et al.   FOOD AND CHEMICAL TOXICOLOGY

The Effects of Dietary Phenolic Compounds on Cytokine and Antioxidant Production by A549 Cells

(2008) Benoit Gauliard et al.   JOURNAL OF MEDICINAL FOOD

Pomegranate Juice and Extracts Provide Similar Levels of Plasma and Urinary Ellagitannin Metabolites in Human Subjects

(2008) Navindra P. Seeram et al.   JOURNAL OF MEDICINAL FOOD

Cancer chemoprevention and chemotherapy: Dietary polyphenols and signalling pathways

(2008) Sonia Ramos   MOLECULAR NUTRITION & FOOD RESEARCH

Inhibition of cadmium-induced oxidative injury in rat primary astrocytes by the addition of antioxidants and the reduction of intracellular calcium

(2007) Chung-Shi Yang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY