Identification of Estrogen Receptor α Antagonists from Natural Products via In Vitro and In Silico Approaches

Ameliorative role of genistein against age-dependent chronic arsenic toxicity in murine brains via the regulation of oxidative stress and inflammatory signaling cascades

(2018) Sukanya Saha et al.   JOURNAL OF NUTRITIONAL BIOCHEMISTRY

Effects of P-Glycoprotein on the Transport of DL0410, a Potential Multifunctional Anti-Alzheimer Agent

(2017) Xiaocong Pang et al.   MOLECULES

Evaluation of Novel Dual Acetyl- and Butyrylcholinesterase Inhibitors as Potential Anti-Alzheimer’s Disease Agents Using Pharmacophore, 3D-QSAR, and Molecular Docking Approaches

(2017) Xiaocong Pang et al.   MOLECULES

Synthesis and structure–activity relationships of novel hybrid ferrocenyl compounds based on a bicyclic core skeleton for breast cancer therapy

(2016) Changhao Li et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Self-Organizing Map (SOM) and Support Vector Machine (SVM) Models for the Prediction of Human Epidermal Growth Factor Receptor (EGFR/ ErbB-1) Inhibitors

(2016) Yue Kong et al.   COMBINATORIAL CHEMISTRY & HIGH THROUGHPUT SCREENING

Design, synthesis and evaluation of 6-aryl-indenoisoquinolone derivatives dual targeting ERα and VEGFR-2 as anti-breast cancer agents

(2016) Zhichao Tang et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Characterization of a selective inverse agonist for estrogen related receptor α as a potential agent for breast cancer

(2016) Liudi Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Use of machine learning approaches for novel drug discovery

(2016) Angélica Nakagawa Lima et al.   Expert Opinion on Drug Discovery

Identification of estrogen receptor α ligands with virtual screening techniques

(2016) Sanna P. Niinivehmas et al.   JOURNAL OF MOLECULAR GRAPHICS & MODELLING

Structure–activity relationship study of diphenylamine-based estrogen receptor (ER) antagonists

(2015) Kiminori Ohta et al.   BIOORGANIC & MEDICINAL CHEMISTRY

Review of natural product databases

(2015) Tao Xie et al.   CELL PROLIFERATION

Machine-learning approaches in drug discovery: methods and applications

(2015) Antonio Lavecchia   DRUG DISCOVERY TODAY

Estrogen-related receptor alpha and cancer: axis of evil

(2015) Harmit S. Ranhotra   JOURNAL OF RECEPTORS AND SIGNAL TRANSDUCTION

Selective estrogen-receptor modulators suppress microglial activation and neuronal cell death via an estrogen receptor-dependent pathway

(2015) Yasuhiro Ishihara et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

CEMTDD: Chinese Ethnic Minority Traditional Drug Database

(2014) Jian Huang et al.   APOPTOSIS

Characterization of estrogen receptor α activities in polychlorinated biphenyls by in vitro dual-luciferase reporter gene assay

(2014) Quan Zhang et al.   ENVIRONMENTAL POLLUTION

Flavonoids from Herba epimedii selectively activate estrogen receptor alpha (ERα) and stimulate ER-dependent osteoblastic functions in UMR-106 cells

(2014) Hui-Hui Xiao et al.   JOURNAL OF STEROID BIOCHEMISTRY AND MOLECULAR BIOLOGY

Amorphous solid dispersion with increased gastric solubility in tandem with oral disintegrating tablets: a successful approach to improve the bioavailability of atorvastatin

(2014) Jumah Masoud M. Salmani et al.   PHARMACEUTICAL DEVELOPMENT AND TECHNOLOGY

Phloretin promotes osteoclast apoptosis in murine macrophages and inhibits estrogen deficiency-induced osteoporosis in mice

(2014) Eun-Jung Lee et al.   PHYTOMEDICINE

Estrogen receptors alpha (ERα) and beta (ERβ): Subtype-selective ligands and clinical potential

(2014) Ilaria Paterni et al.   STEROIDS

TCMSP: a database of systems pharmacology for drug discovery from herbal medicines

(2014) Jinlong Ru et al.   Journal of Cheminformatics

Novel drugs that target the estrogen-related receptor alpha: their therapeutic potential in breast cancer

(2014) Felicity May   Cancer Management and Research

Predictions of BuChE Inhibitors Using Support Vector Machine and Naive Bayesian Classification Techniques in Drug Discovery

(2013) Jiansong Fang et al.   Journal of Chemical Information and Modeling

Estrogen and estrogen receptors in cardiovascular oxidative stress

(2013) Paula-Anahi Arias-Loza et al.   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

admetSAR: A Comprehensive Source and Free Tool for Assessment of Chemical ADMET Properties

(2012) Feixiong Cheng et al.   Journal of Chemical Information and Modeling

Directory of Useful Decoys, Enhanced (DUD-E): Better Ligands and Decoys for Better Benchmarking

(2012) Michael M. Mysinger et al.   JOURNAL OF MEDICINAL CHEMISTRY

TCMID: traditional Chinese medicine integrative database for herb molecular mechanism analysis

(2012) Ruichao Xue et al.   NUCLEIC ACIDS RESEARCH

ADME Evaluation in Drug Discovery. 10. Predictions of P-Glycoprotein Inhibitors Using Recursive Partitioning and Naive Bayesian Classification Techniques

(2011) Lei Chen et al.   MOLECULAR PHARMACEUTICS

TCM Database@Taiwan: The World's Largest Traditional Chinese Medicine Database for Drug Screening In Silico

(2011) Calvin Yu-Chian Chen   PLoS One

Estrogen Receptors: Therapies Targeted to Receptor Subtypes

(2010) S Nilsson et al.   CLINICAL PHARMACOLOGY & THERAPEUTICS

Factors to Consider in the Association Between Soy Isoflavone Intake and Breast Cancer Risk

(2010) Chisato Nagata   JOURNAL OF EPIDEMIOLOGY

Recent Advances in Selective Estrogen Receptor Modulators for Breast Cancer

(2009) Tianlin Wang et al.   MINI-REVIEWS IN MEDICINAL CHEMISTRY

SuperToxic: a comprehensive database of toxic compounds

(2008) U. Schmidt et al.   NUCLEIC ACIDS RESEARCH