Metabolic crosstalk in the tumor microenvironment regulates antitumor immunosuppression and immunotherapy resisitance
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Title
Metabolic crosstalk in the tumor microenvironment regulates antitumor immunosuppression and immunotherapy resisitance
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Journal
CELLULAR AND MOLECULAR LIFE SCIENCES
Volume -, Issue -, Pages -
Publisher
Springer Science and Business Media LLC
Online
2020-07-11
DOI
10.1007/s00018-020-03581-0
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Note: Only part of the references are listed.- Abnormal X chromosome inactivation and tumor development
- (2020) Dan Wang et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Top 10 Challenges in Cancer Immunotherapy
- (2020) Priti S. Hegde et al. IMMUNITY
- Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapy
- (2020) Daixi Ren et al. Molecular Cancer
- Tumor Microenvironment, Metabolism, and Immunotherapy
- (2020) Ralph J. DeBerardinis NEW ENGLAND JOURNAL OF MEDICINE
- Epstein‐Barr virus‐encoded miR‐BART6‐3p inhibits cancer cell proliferation through the LOC553103‐STMN1 axis
- (2020) Dan Wang et al. FASEB JOURNAL
- LncRNA AATBC regulates Pinin to promote metastasis in nasopharyngeal carcinoma
- (2020) Ting Tang et al. Molecular Oncology
- Intestinal Flora and Disease Mutually Shape the Regional Immune System in the Intestinal Tract
- (2020) Bolun Zhou et al. Frontiers in Immunology
- Circulating Tumor Cell Clustering Shapes DNA Methylation to Enable Metastasis Seeding
- (2019) Sofia Gkountela et al. CELL
- Role of the tumor microenvironment in PD-L1/PD-1-mediated tumor immune escape
- (2019) Xianjie Jiang et al. Molecular Cancer
- Molecular landmarks of tumor hypoxia across cancer types
- (2019) Vinayak Bhandari et al. NATURE GENETICS
- The P2X7 receptor modulates immune cells infiltration, ectonucleotidases expression and extracellular ATP levels in the tumor microenvironment
- (2019) Elena De Marchi et al. ONCOGENE
- T cell stemness and dysfunction in tumors are triggered by a common mechanism
- (2019) Suman Kumar Vodnala et al. SCIENCE
- Upregulation and hypomethylation of lncRNA AFAP1‑AS1 predicts a poor prognosis and promotes the migration and invasion of cervical cancer
- (2019) Hao Bo et al. ONCOLOGY REPORTS
- Navigating metabolic pathways to enhance antitumour immunity and immunotherapy
- (2019) Xiaoyun Li et al. Nature Reviews Clinical Oncology
- Proteomics identifies new therapeutic targets of early-stage hepatocellular carcinoma
- (2019) Ying Jiang et al. NATURE
- Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity
- (2019) Kim Vriens et al. NATURE
- Natural killer group 2D receptor and its ligands in cancer immune escape
- (2019) Shixin Duan et al. Molecular Cancer
- Blocking TREM-1+ Tumor-associated macrophages induced by hypoxia reverses immunosuppression and anti-PD-L1 resistance in liver cancer
- (2019) Qinchuan Wu et al. HEPATOLOGY
- Membrane Cholesterol Efflux Drives Tumor-Associated Macrophage Reprogramming and Tumor Progression
- (2019) Pieter Goossens et al. Cell Metabolism
- Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
- (2019) Christopher J. Halbrook et al. Cell Metabolism
- Impact of hypoxic tumor microenvironment and tumor cell plasticity on the expression of immune checkpoints
- (2019) Audrey LEQUEUX et al. CANCER LETTERS
- TSC22D2 identified as a candidate susceptibility gene of multi-cancer pedigree using genome-wide linkage analysis and whole exome sequencing
- (2019) Lan Xiao et al. CARCINOGENESIS
- Adaptive Immune Resistance Emerges from Tumor-Initiating Stem Cells
- (2019) Yuxuan Miao et al. CELL
- Pembrolizumab versus chemotherapy for previously untreated, PD-L1-expressing, locally advanced or metastatic non-small-cell lung cancer (KEYNOTE-042): a randomised, open-label, controlled, phase 3 trial
- (2019) Tony S K Mok et al. LANCET
- Fatty acid transport protein 2 reprograms neutrophils in cancer
- (2019) Filippo Veglia et al. NATURE
- Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy
- (2019) Mauro Di Pilato et al. NATURE
- Extracellular vesicle-packaged HIF-1α-stabilizing lncRNA from tumour-associated macrophages regulates aerobic glycolysis of breast cancer cells
- (2019) Fei Chen et al. NATURE CELL BIOLOGY
- Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
- (2019) Ivan Perrot et al. Cell Reports
- Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells
- (2019) Zhilin Hu et al. Cell Metabolism
- Long non-coding RNA PVT1 interacts with MYC and its downstream molecules to synergistically promote tumorigenesis
- (2019) Ke Jin et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Acquired resistance to cancer immunotherapy: Role of tumor-mediated immunosuppression
- (2019) Reem Saleh et al. SEMINARS IN CANCER BIOLOGY
- Glutamine Synthetase Promotes Radiation Resistance via Facilitating Nucleotide Metabolism and Subsequent DNA Damage Repair
- (2019) Shujun Fu et al. Cell Reports
- Metabolic Control of Dendritic Cell Functions: Digesting Information
- (2019) Stefanie K. Wculek et al. Frontiers in Immunology
- Lipid Metabolic Pathways Confer the Immunosuppressive Function of Myeloid-Derived Suppressor Cells in Tumor
- (2019) Dehong Yan et al. Frontiers in Immunology
- PVT1 Promotes Cancer Progression via MicroRNAs
- (2019) Wenxi Wang et al. Frontiers in Oncology
- MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer
- (2019) Niranjan Venkateswaran et al. GENES & DEVELOPMENT
- Neoantigen vaccine: an emerging tumor immunotherapy
- (2019) Miao Peng et al. Molecular Cancer
- PTEN Suppresses Glycolysis by Dephosphorylating and Inhibiting Autophosphorylated PGK1
- (2019) Xu Qian et al. MOLECULAR CELL
- GLS2 is protumorigenic in breast cancers
- (2019) Marilia M. Dias et al. ONCOGENE
- Dendritic Cell Metabolism and Function in Tumors
- (2019) Paolo Giovanelli et al. TRENDS IN IMMUNOLOGY
- Glutamine blockade induces divergent metabolic programs to overcome tumor immune evasion
- (2019) Robert D. Leone et al. SCIENCE
- Metabolic landscape of the tumor microenvironment at single cell resolution
- (2019) Zhengtao Xiao et al. Nature Communications
- Metabolomic adaptations and correlates of survival to immune checkpoint blockade
- (2019) Haoxin Li et al. Nature Communications
- Targeting L-Lactate Metabolism to Overcome Resistance to Immune Therapy of Melanoma and Other Tumor Entities
- (2019) René G. Feichtinger et al. Journal of Oncology
- Mechanisms of resistance to immune checkpoint inhibitors
- (2018) Russell W Jenkins et al. BRITISH JOURNAL OF CANCER
- Metabolic changes in tumor cells and tumor-associated macrophages: A mutual relationship
- (2018) Romana T. Netea-Maier et al. CANCER LETTERS
- As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
- (2018) Natalya N. Pavlova et al. Cell Metabolism
- Increased Tumor Glycolysis Characterizes Immune Resistance to Adoptive T Cell Therapy
- (2018) Tina Cascone et al. Cell Metabolism
- Recent progress in therapeutic antibodies for cancer immunotherapy
- (2018) Anthony Lee et al. CURRENT OPINION IN CHEMICAL BIOLOGY
- Myeloid derived-suppressor cells: their role in cancer and obesity
- (2018) Suzanne Ostrand-Rosenberg CURRENT OPINION IN IMMUNOLOGY
- Recent Development of Small Molecule Glutaminase Inhibitors
- (2018) Minsoo Song et al. CURRENT TOPICS IN MEDICINAL CHEMISTRY
- Glucose transporters in cancer - from tumor cells to the tumor microenvironment
- (2018) Pierre-Benoit Ancey et al. FEBS Journal
- Macrophage plasticity, polarization, and function in health and disease
- (2018) Abbas Shapouri-Moghaddam et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Role of metabolism in cancer cell radioresistance and radiosensitization methods
- (2018) Le Tang et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Emerging role of lipid metabolism alterations in Cancer stem cells
- (2018) Mei Yi et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities
- (2018) Yazhuo Zhang et al. Molecular Cancer
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- (2018) Yajuan Zhang et al. MOLECULAR CELL
- The gut microbiota influences anticancer immunosurveillance and general health
- (2018) Bertrand Routy et al. Nature Reviews Clinical Oncology
- IDO takes a blow
- (2018) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- The commensal microbiome is associated with anti–PD-1 efficacy in metastatic melanoma patients
- (2018) Vyara Matson et al. SCIENCE
- Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression
- (2018) Wei Xiang et al. Nature Communications
- Transfer of miRNA in Macrophage-Derived Exosomes Induces Drug Resistance in Pancreatic Adenocarcinoma
- (2018) Yoav Binenbaum et al. CANCER RESEARCH
- A Role for p53 in the Adaptation to Glutamine Starvation through the Expression of SLC1A3
- (2018) Mylène Tajan et al. Cell Metabolism
- Hippo/Mst signalling couples metabolic state and immune function of CD8α+ dendritic cells
- (2018) Xingrong Du et al. NATURE
- A2AR Antagonism with CPI-444 Induces Antitumor Responses and Augments Efficacy to Anti–PD-(L)1 and Anti–CTLA-4 in Preclinical Models
- (2018) Stephen B. Willingham et al. Cancer Immunology Research
- Targeting T Cell Metabolism for Improvement of Cancer Immunotherapy
- (2018) Thibault Le Bourgeois et al. Frontiers in Oncology
- Distinct Regulation of Th17 and Th1 Cell Differentiation by Glutaminase-Dependent Metabolism
- (2018) Marc O. Johnson et al. CELL
- A Paradigm Shift in Cancer Immunotherapy: From Enhancement to Normalization
- (2018) Miguel F. Sanmamed et al. CELL
- Roles of the immune system in cancer: from tumor initiation to metastatic progression
- (2018) Hugo Gonzalez et al. GENES & DEVELOPMENT
- Lactate inhibits ATP6V0d2 expression in tumor-associated macrophages to promote HIF-2α–mediated tumor progression
- (2018) Na Liu et al. JOURNAL OF CLINICAL INVESTIGATION
- Effects of tumor metabolic microenvironment on regulatory T cells
- (2018) Yi-an Wang et al. Molecular Cancer
- Altered cancer metabolism in mechanisms of immunotherapy resistance
- (2018) Rishab Ramapriyan et al. PHARMACOLOGY & THERAPEUTICS
- Systems biology–based drug repositioning identifies digoxin as a potential therapy for groups 3 and 4 medulloblastoma
- (2018) Lei Huang et al. Science Translational Medicine
- Biosynthetic energy cost for amino acids decreases in cancer evolution
- (2018) Hong Zhang et al. Nature Communications
- Lactate: A Metabolic Driver in the Tumour Landscape
- (2018) Luigi Ippolito et al. TRENDS IN BIOCHEMICAL SCIENCES
- Regulatory T Cell Migration Is Dependent on Glucokinase-Mediated Glycolysis
- (2017) Madhav Kishore et al. IMMUNITY
- The future of immune checkpoint cancer therapy after PD-1 and CTLA-4
- (2017) Andrew W Hahn et al. Immunotherapy
- Therapeutic T cell engineering
- (2017) Michel Sadelain et al. NATURE
- Inflammation, metaflammation and immunometabolic disorders
- (2017) Gökhan S. Hotamisligil NATURE
- Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells
- (2017) J Feng et al. ONCOGENE
- The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
- (2017) Geoffrey Burnstock et al. Purinergic Signalling
- Gut microbiome modulates response to anti–PD-1 immunotherapy in melanoma patients
- (2017) V. Gopalakrishnan et al. SCIENCE
- Gut microbiome influences efficacy of PD-1–based immunotherapy against epithelial tumors
- (2017) Bertrand Routy et al. SCIENCE
- Reprogramming of the Tumor in the Hypoxic Niche: The Emerging Concept and Associated Therapeutic Strategies
- (2017) Guan-Zhong Qiu et al. TRENDS IN PHARMACOLOGICAL SCIENCES
- Metabolic interactions in cancer: cellular metabolism at the interface between the microenvironment, the cancer cell phenotype and the epigenetic landscape
- (2017) Gianmarco Rinaldi et al. Wiley Interdisciplinary Reviews-Systems Biology and Medicine
- INCB24360 (Epacadostat), a Highly Potent and Selective Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitor for Immuno-oncology
- (2017) Eddy W. Yue et al. ACS Medicinal Chemistry Letters
- Compensatory metabolic networks in pancreatic cancers upon perturbation of glutamine metabolism
- (2017) Douglas E. Biancur et al. Nature Communications
- Oncogenic MYC Activates a Feedforward Regulatory Loop Promoting Essential Amino Acid Metabolism and Tumorigenesis
- (2017) Ming Yue et al. Cell Reports
- Role of tumor microenvironment in tumorigenesis
- (2017) Maonan Wang et al. Journal of Cancer
- PD-1 and PD-L1 Checkpoint Signaling Inhibition for Cancer Immunotherapy: Mechanism, Combinations, and Clinical Outcome
- (2017) Hashem O. Alsaab et al. Frontiers in Pharmacology
- Metabolic Adaptation of Human CD4+ and CD8+ T-Cells to T-Cell Receptor-Mediated Stimulation
- (2017) Nicholas Jones et al. Frontiers in Immunology
- Metabolic Hallmarks of Tumor and Immune Cells in the Tumor Microenvironment
- (2017) Kathrin Renner et al. Frontiers in Immunology
- Exogenous lipid uptake induces metabolic and functional reprogramming of tumor-associated myeloid-derived suppressor cells
- (2017) Amir A. Al-Khami et al. OncoImmunology
- Tumor-associated macrophages: Potential therapeutic targets for anti-cancer therapy
- (2016) Yoshihiro Komohara et al. ADVANCED DRUG DELIVERY REVIEWS
- CTLA-4 and PD-1 Pathways
- (2016) Elizabeth I. Buchbinder et al. AMERICAN JOURNAL OF CLINICAL ONCOLOGY-CANCER CLINICAL TRIALS
- The Emerging Hallmarks of Cancer Metabolism
- (2016) Natalya N. Pavlova et al. Cell Metabolism
- LDHA-Associated Lactic Acid Production Blunts Tumor Immunosurveillance by T and NK Cells
- (2016) Almut Brand et al. Cell Metabolism
- Regulatory T cells in cancer immunotherapy
- (2016) Atsushi Tanaka et al. CELL RESEARCH
- Reprogramming mitochondrial metabolism in macrophages as an anti-inflammatory signal
- (2016) Evanna L. Mills et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Comprehensive Proteomics Analysis Reveals Metabolic Reprogramming of Tumor-Associated Macrophages Stimulated by the Tumor Microenvironment
- (2016) Di Liu et al. JOURNAL OF PROTEOME RESEARCH
- Hypoxia-inducible factor 1–mediated characteristic features of cancer cells for tumor radioresistance
- (2016) Hiroshi Harada JOURNAL OF RADIATION RESEARCH
- Tumour hypoxia causes DNA hypermethylation by reducing TET activity
- (2016) Bernard Thienpont et al. NATURE
- Potentiating the antitumour response of CD8+ T cells by modulating cholesterol metabolism
- (2016) Wei Yang et al. NATURE
- Targeting renal cell carcinoma with a HIF-2 antagonist
- (2016) Wenfang Chen et al. NATURE
- Ionic immune suppression within the tumour microenvironment limits T cell effector function
- (2016) Robert Eil et al. NATURE
- Inhibition of acetyl-CoA carboxylase suppresses fatty acid synthesis and tumor growth of non-small-cell lung cancer in preclinical models
- (2016) Robert U Svensson et al. NATURE MEDICINE
- Cancer metabolism pipeline breaks new ground
- (2016) Asher Mullard NATURE REVIEWS DRUG DISCOVERY
- Arginine dependence of tumor cells: targeting a chink in cancer’s armor
- (2016) M D Patil et al. ONCOGENE
- Hypoxic stress: obstacles and opportunities for innovative immunotherapy of cancer
- (2016) S Chouaib et al. ONCOGENE
- Therapeutic targeting of hypoxia and hypoxia-inducible factors in cancer
- (2016) Caroline Wigerup et al. PHARMACOLOGY & THERAPEUTICS
- Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m6A-demethylation of NANOG mRNA
- (2016) Chuanzhao Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IDO in the Tumor Microenvironment: Inflammation, Counter-Regulation, and Tolerance
- (2016) David H. Munn et al. TRENDS IN IMMUNOLOGY
- The Nature of Myeloid-Derived Suppressor Cells in the Tumor Microenvironment
- (2016) Vinit Kumar et al. TRENDS IN IMMUNOLOGY
- High expression of CD39 in gastric cancer reduces patient outcome following radical resection
- (2016) Xiao-Yan Cai et al. Oncology Letters
- A Metabolic Immune Checkpoint: Adenosine in Tumor Microenvironment
- (2016) Akio Ohta Frontiers in Immunology
- Fundamentals of cancer metabolism
- (2016) R. J. DeBerardinis et al. Science Advances
- Acetyl-CoA Synthetase 2 Promotes Acetate Utilization and Maintains Cancer Cell Growth under Metabolic Stress
- (2015) Zachary T. Schug et al. CANCER CELL
- Regulation of Glutamine Carrier Proteins by RNF5 Determines Breast Cancer Response to ER Stress-Inducing Chemotherapies
- (2015) Young Joo Jeon et al. CANCER CELL
- ER Stress Sensor XBP1 Controls Anti-tumor Immunity by Disrupting Dendritic Cell Homeostasis
- (2015) Juan R. Cubillos-Ruiz et al. CELL
- Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
- (2015) Ping-Chih Ho et al. CELL
- Metabolic Competition in the Tumor Microenvironment Is a Driver of Cancer Progression
- (2015) Chih-Hao Chang et al. CELL
- Molecular Pathways: Targeting IDO1 and Other Tryptophan Dioxygenases for Cancer Immunotherapy
- (2015) L. Zhai et al. CLINICAL CANCER RESEARCH
- Emerging Roles of P2X Receptors in Cancer
- (2015) Elena Adinolfi et al. CURRENT MEDICINAL CHEMISTRY
- 514 Results of Phase 1b trial of the Indoleamine 2,3-dioxygenase (IDO) Pathway Inhibitor Indoximod plus Ipilimumab for the treatment of unresectable stage III or IV melanoma
- (2015) Y. Zakharia et al. EUROPEAN JOURNAL OF CANCER
- Metabolic Reprogramming of Immune Cells in Cancer Progression
- (2015) Subhra K. Biswas IMMUNITY
- Active Immunotherapy of Cancer
- (2015) Thinle Chodon et al. IMMUNOLOGICAL INVESTIGATIONS
- Regulators of Glucose Metabolism in CD4+ and CD8+ T Cells
- (2015) Clovis S. Palmer et al. INTERNATIONAL REVIEWS OF IMMUNOLOGY
- A dendritic-cell brake on antitumour immunity
- (2015) Miriam Merad et al. NATURE
- Metabolic pathways promoting cancer cell survival and growth
- (2015) Lindsey K. Boroughs et al. NATURE CELL BIOLOGY
- Cancer mediates effector T cell dysfunction by targeting microRNAs and EZH2 via glycolysis restriction
- (2015) Ende Zhao et al. NATURE IMMUNOLOGY
- CREB pathway links PGE2 signaling with macrophage polarization
- (2015) Bing Luan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Commensal Bifidobacterium promotes antitumor immunity and facilitates anti-PD-L1 efficacy
- (2015) A. Sivan et al. SCIENCE
- Anticancer immunotherapy by CTLA-4 blockade relies on the gut microbiota
- (2015) M. Vetizou et al. SCIENCE
- Immune evasion in cancer: Mechanistic basis and therapeutic strategies
- (2015) Dass S. Vinay et al. SEMINARS IN CANCER BIOLOGY
- Confusing signals: Recent progress in CTLA-4 biology
- (2015) Lucy S.K. Walker et al. TRENDS IN IMMUNOLOGY
- T cell metabolic fitness in antitumor immunity
- (2015) Peter J. Siska et al. TRENDS IN IMMUNOLOGY
- Fatty acid metabolism in the regulation of T cell function
- (2015) Matthias Lochner et al. TRENDS IN IMMUNOLOGY
- Lactate Regulates Metabolic and Pro-inflammatory Circuits in Control of T Cell Migration and Effector Functions
- (2015) Robert Haas et al. PLOS BIOLOGY
- Inhibition of Fatty Acid Oxidation Modulates Immunosuppressive Functions of Myeloid-Derived Suppressor Cells and Enhances Cancer Therapies
- (2015) F. Hossain et al. Cancer Immunology Research
- Glucose Metabolism Regulates T Cell Activation, Differentiation, and Functions
- (2015) Clovis S. Palmer et al. Frontiers in Immunology
- Controlling T cell senescence in the tumor microenvironment for tumor immunotherapy
- (2015) Jian Ye et al. OncoImmunology
- Follow the ATP: Tumor Energy Production: A Perspective
- (2014) Bryan Oronsky et al. Anti-Cancer Agents in Medicinal Chemistry
- Gangliosides Drive the Tumor Infiltration and Function of Myeloid-Derived Suppressor Cells
- (2014) A. Wondimu et al. CANCER RESEARCH
- L-Arginine Depletion Blunts Antitumor T-cell Responses by Inducing Myeloid-Derived Suppressor Cells
- (2014) M. Fletcher et al. CANCER RESEARCH
- The Glucose Transporter Glut1 Is Selectively Essential for CD4 T Cell Activation and Effector Function
- (2014) Andrew N. Macintyre et al. Cell Metabolism
- Hypoxic Regulation of Glutamine Metabolism through HIF1 and SIAH2 Supports Lipid Synthesis that Is Necessary for Tumor Growth
- (2014) Ramon C. Sun et al. Cell Metabolism
- TLR8 signaling enhances tumor immunity by preventing tumor-induced T-cell senescence
- (2014) J. Ye et al. EMBO Molecular Medicine
- PD-L1 is a novel direct target of HIF-1α, and its blockade under hypoxia enhanced MDSC-mediated T cell activation
- (2014) Muhammad Zaeem Noman et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Metabolic Reprogramming towards Aerobic Glycolysis Correlates with Greater Proliferative Ability and Resistance to Metabolic Inhibition in CD8 versus CD4 T Cells
- (2014) Yilin Cao et al. PLoS One
- Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages
- (2014) Meera Rath et al. Frontiers in Immunology
- Posttranscriptional Control of T Cell Effector Function by Aerobic Glycolysis
- (2013) Chih-Hao Chang et al. CELL
- Cellular Fatty Acid Metabolism and Cancer
- (2013) Erin Currie et al. Cell Metabolism
- A proposed role for glutamine in cancer cell growth through acid resistance
- (2013) Weijiao Huang et al. CELL RESEARCH
- Altered Glutamine Metabolism and Therapeutic Opportunities for Lung Cancer
- (2013) Amr Mohamed et al. Clinical Lung Cancer
- M1 and M2 Macrophages: Oracles of Health and Disease
- (2013) Charles Mills CRITICAL REVIEWS IN IMMUNOLOGY
- Fatty acid synthase plays a role in cancer metabolism beyond providing fatty acids for phospholipid synthesis or sustaining elevations in glycolytic activity
- (2013) Kathryn E. Hopperton et al. EXPERIMENTAL CELL RESEARCH
- Metabolic Pathways in Immune Cell Activation and Quiescence
- (2013) Erika L. Pearce et al. IMMUNITY
- Glutamine and cancer: cell biology, physiology, and clinical opportunities
- (2013) Christopher T. Hensley et al. JOURNAL OF CLINICAL INVESTIGATION
- ACAT Inhibitors: The Search for Novel Cholesterol Lowering Agents
- (2013) Palash Pal et al. MINI-REVIEWS IN MEDICINAL CHEMISTRY
- Tumor glycolysis as a target for cancer therapy: progress and prospects
- (2013) Shanmugasundaram Ganapathy-Kanniappan et al. Molecular Cancer
- Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway
- (2013) Jaekyoung Son et al. NATURE
- mTORC1 couples immune signals and metabolic programming to establish Treg-cell function
- (2013) Hu Zeng et al. NATURE
- Fueling Immunity: Insights into Metabolism and Lymphocyte Function
- (2013) E. L. Pearce et al. SCIENCE
- Tryptophan Catabolism in Cancer: Beyond IDO and Tryptophan Depletion
- (2012) M. Platten et al. CANCER RESEARCH
- Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy
- (2012) T. W. H. Meijer et al. CLINICAL CANCER RESEARCH
- Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function
- (2012) Eóin N. McNamee et al. IMMUNOLOGIC RESEARCH
- Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives
- (2012) Patrick Raber et al. IMMUNOLOGICAL INVESTIGATIONS
- Metabolism in 'the driver's seat
- (2012) Luisa Tasselli et al. NATURE
- Safety, Activity, and Immune Correlates of Anti–PD-1 Antibody in Cancer
- (2012) Suzanne L. Topalian et al. NEW ENGLAND JOURNAL OF MEDICINE
- Cancer metabolism: current perspectives and future directions
- (2012) C Muñoz-Pinedo et al. Cell Death & Disease
- Hallmarks of Cancer: The Next Generation
- (2011) Douglas Hanahan et al. CELL
- Regulation of Immune Responses by Prostaglandin E2
- (2011) P. Kalinski JOURNAL OF IMMUNOLOGY
- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
- (2011) Andrea Facciabene et al. NATURE
- T cell exhaustion
- (2011) E John Wherry NATURE IMMUNOLOGY
- The role of p53 in glucose metabolism
- (2010) Eric C Cheung et al. CURRENT OPINION IN CELL BIOLOGY
- Metabolism in T cell activation and differentiation
- (2010) Erika L Pearce CURRENT OPINION IN IMMUNOLOGY
- An Interaction between Kynurenine and the Aryl Hydrocarbon Receptor Can Generate Regulatory T Cells
- (2010) J. D. Mezrich et al. JOURNAL OF IMMUNOLOGY
- Macrophage plasticity and interaction with lymphocyte subsets: cancer as a paradigm
- (2010) Subhra K Biswas et al. NATURE IMMUNOLOGY
- Improved Survival with Ipilimumab in Patients with Metastatic Melanoma
- (2010) F. Stephen Hodi et al. NEW ENGLAND JOURNAL OF MEDICINE
- Extracellular adenosine triphosphate and adenosine in cancer
- (2010) J Stagg et al. ONCOGENE
- The Control of the Metabolic Switch in Cancers by Oncogenes and Tumor Suppressor Genes
- (2010) A. J. Levine et al. SCIENCE
- The mTOR Kinase Differentially Regulates Effector and Regulatory T Cell Lineage Commitment
- (2009) Greg M. Delgoffe et al. IMMUNITY
- Lactic Acid and Acidification Inhibit TNF Secretion and Glycolysis of Human Monocytes
- (2009) K. Dietl et al. JOURNAL OF IMMUNOLOGY
- mTOR regulates memory CD8 T-cell differentiation
- (2009) Koichi Araki et al. NATURE
- Q's next: the diverse functions of glutamine in metabolism, cell biology and cancer
- (2009) R J DeBerardinis et al. ONCOGENE
- Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
- (2009) M. G. Vander Heiden et al. SCIENCE
- Arginine regulation by myeloid derived suppressor cells and tolerance in cancer: mechanisms and therapeutic perspectives
- (2008) Paulo C. Rodríguez et al. IMMUNOLOGICAL REVIEWS
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