The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
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Title
The potential of P2X7 receptors as a therapeutic target, including inflammation and tumour progression
Authors
Keywords
Pain, Infection, Cancer, CNS disorders, Cardiovascular, Airways, Diabetes, Kidney, Bladder, Liver, Gut, Immune cells
Journal
Purinergic Signalling
Volume 14, Issue 1, Pages 1-18
Publisher
Springer Nature
Online
2017-11-22
DOI
10.1007/s11302-017-9593-0
References
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- Efficacy and Safety of Diquafosol Ophthalmic Solution in Patients with Dry Eye Syndrome: A Japanese Phase 2 Clinical Trial
- (2012) Yukihiro Matsumoto et al. OPHTHALMOLOGY
- Activation of P2X7 Receptor by ATP Plays an Important Role in Regulating Inflammatory Responses during Acute Viral Infection
- (2012) Benjamin H. Lee et al. PLoS One
- Purinergic Receptor Antagonist A438079 Protects Against Acetaminophen-Induced Liver Injury by Inhibiting P450 Isoenzymes, Not by Inflammasome Activation
- (2012) Yuchao Xie et al. TOXICOLOGICAL SCIENCES
- The Neuroprotective Effect of a Specific P2X7 Receptor Antagonist Derives from its Ability to Inhibit Assembly of the NLRP3 Inflammasome in Glial Cells
- (2011) Niamh Murphy et al. BRAIN PATHOLOGY
- The role of P2X7 purinergic receptors in inflammatory and nociceptive changes accompanying cyclophosphamide-induced haemorrhagic cystitis in mice
- (2011) JP Martins et al. BRITISH JOURNAL OF PHARMACOLOGY
- Hypoxia-increased RAGE and P2X7R expression regulates tumor cell invasion through phosphorylation of Erk1/2 and Akt and nuclear translocation of NF-κB
- (2011) Marco Tafani et al. CARCINOGENESIS
- P2X7 receptor antagonism attenuates the hypertension and renal injury in Dahl salt-sensitive rats
- (2011) Xu Ji et al. HYPERTENSION RESEARCH
- Anthrax Toxin Induces Macrophage Death by p38 MAPK Inhibition but Leads to Inflammasome Activation via ATP Leakage
- (2011) Syed Raza Ali et al. IMMUNITY
- UV-B induced alteration in purinergic receptors and signaling on HaCaT keratinocytes
- (2011) Olga Ruzsnavszky et al. JOURNAL OF PHOTOCHEMISTRY AND PHOTOBIOLOGY B-BIOLOGY
- Inhibition of the P2X7 Receptor Reduces Cystogenesis in PKD
- (2011) M.-Y. Chang et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- European meeting “P2 receptors: new targets for the treatment of osteoporosis”
- (2011) Niklas Rye Jørgensen et al. Purinergic Signalling
- Lipopolysaccharide-induced lung injury: Role of P2X7 receptor
- (2011) Leonardo C. Monção-Ribeiro et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- P2X7Receptor Signaling in the Pathogenesis of Smoke-Induced Lung Inflammation and Emphysema
- (2010) Monica Lucattelli et al. AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY
- Structure–activity relationships and in vivo activity of (1H-pyrazol-4-yl)acetamide antagonists of the P2X7 receptor
- (2010) Paul J. Beswick et al. BIOORGANIC & MEDICINAL CHEMISTRY LETTERS
- AF-353, a novel, potent and orally bioavailable P2X3/P2X2/3 receptor antagonist
- (2010) Joel R Gever et al. BRITISH JOURNAL OF PHARMACOLOGY
- Lack of the purinergic receptor P2X7results in resistance to contact hypersensitivity
- (2010) Felix C. Weber et al. JOURNAL OF EXPERIMENTAL MEDICINE
- The effects of P2X7 receptor antagonists on the formation and function of human osteoclasts in vitro
- (2010) Ankita Agrawal et al. Purinergic Signalling
- Activation of P2X7-mediated apoptosis Inhibits DMBA/TPA-induced formation of skin papillomas and cancer in mice
- (2009) Wen Fu et al. BMC CANCER
- Atypical P2X7 receptor pharmacology in two human osteoblast-like cell lines
- (2009) SM Alqallaf et al. BRITISH JOURNAL OF PHARMACOLOGY
- P2X7-mediated chemoprevention of epithelial cancers
- (2009) George I Gorodeski EXPERT OPINION ON THERAPEUTIC TARGETS
- Altered P2X7-receptor level and function in mouse models of Huntington’s disease and therapeutic efficacy of antagonist administration
- (2009) Miguel Díaz-Hernández et al. FASEB JOURNAL
- Functional variants of the P2RX7 gene, aseptic osteolysis, and revision of the total hip arthroplasty: A preliminary study
- (2009) F. Mrazek et al. HUMAN IMMUNOLOGY
- Genetics of the P2X7 receptor and human disease
- (2009) Stephen J. Fuller et al. Purinergic Signalling
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