Evidence for an alternative fatty acid desaturation pathway increasing cancer plasticity

Dual loss of succinate dehydrogenase (SDH) and complex I activity is necessary to recapitulate the metabolic phenotype of SDH mutant tumors

(2017) Doriane Lorendeau et al.   METABOLIC ENGINEERING

Lipid desaturation - the next step in targeting lipogenesis in cancer?

(2016) Barrie Peck et al.   FEBS Journal

Breast Cancer-Derived Lung Metastases Show Increased Pyruvate Carboxylase-Dependent Anaplerosis

(2016) Stefan Christen et al.   Cell Reports

Non-small cell lung cancer is characterized by dramatic changes in phospholipid profiles

(2015) Eyra Marien et al.   INTERNATIONAL JOURNAL OF CANCER

Glutamine synthetase activity fuels nucleotide biosynthesis and supports growth of glutamine-restricted glioblastoma

(2015) Saverio Tardito et al.   NATURE CELL BIOLOGY

Hypoxia, lipids, and cancer: surviving the harsh tumor microenvironment

(2014) Daniel Ackerman et al.   TRENDS IN CELL BIOLOGY

Cellular Fatty Acid Metabolism and Cancer

(2013) Erin Currie et al.   Cell Metabolism

The Role of Lipids in the Control of Autophagy

(2013) Claudia Dall'Armi et al.   CURRENT BIOLOGY

Quantitative imaging of membrane lipid order in cells and organisms

(2011) Dylan M Owen et al.   Nature Protocols

SAR and optimization of thiazole analogs as potent stearoyl-CoA desaturase inhibitors

(2010) Yeeman K. Ramtohul et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

De novo Lipogenesis Protects Cancer Cells from Free Radicals and Chemotherapeutics by Promoting Membrane Lipid Saturation

(2010) E. Rysman et al.   CANCER RESEARCH