Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function
Published 2012 View Full Article
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Title
Hypoxia and hypoxia-inducible factors as regulators of T cell development, differentiation, and function
Authors
Keywords
T cell, Oxygen, Hypoxia, Hypoxia-inducible factor, Metabolism
Journal
IMMUNOLOGIC RESEARCH
Volume 55, Issue 1-3, Pages 58-70
Publisher
Springer Nature
Online
2012-09-08
DOI
10.1007/s12026-012-8349-8
References
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Note: Only part of the references are listed.- HIF-1 in T cells ameliorated dextran sodium sulfate-induced murine colitis
- (2012) Masaaki Higashiyama et al. JOURNAL OF LEUKOCYTE BIOLOGY
- A new pharmacological agent (AKB-4924) stabilizes hypoxia inducible factor-1 (HIF-1) and increases skin innate defenses against bacterial infection
- (2012) Cheryl Y. M. Okumura et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- The role of low-level lactate production in airway inflammation in asthma
- (2011) Marina Ostroukhova et al. AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY
- Targeting NF-κB and HIF-1 Pathways for the Treatment of Cancer: Part II
- (2011) Jacek Wilczynski et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
- (2011) J. Schodel et al. BLOOD
- Blocking Hypoxia-Induced Autophagy in Tumors Restores Cytotoxic T-Cell Activity and Promotes Regression
- (2011) M. Z. Noman et al. CANCER RESEARCH
- Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
- (2011) Eric V. Dang et al. CELL
- Current Insights into the Role of HIF-1 in Cutaneous Wound Healing
- (2011) E. Andrikopoulou et al. CURRENT MOLECULAR MEDICINE
- The Transcription Factor Myc Controls Metabolic Reprogramming upon T Lymphocyte Activation
- (2011) Ruoning Wang et al. IMMUNITY
- An Essential Role of the Transcription Factor GATA-3 for the Function of Regulatory T Cells
- (2011) Yunqi Wang et al. IMMUNITY
- Mitochondrial Respiratory Capacity Is a Critical Regulator of CD8+ T Cell Memory Development
- (2011) Gerritje J.W. van der Windt et al. IMMUNITY
- Dynamic regulation of Th17 differentiation by oxygen concentrations
- (2011) A. Ikejiri et al. INTERNATIONAL IMMUNOLOGY
- GATA3 controls Foxp3+ regulatory T cell fate during inflammation in mice
- (2011) Elizabeth A. Wohlfert et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Tregcells
- (2011) Lewis Z. Shi et al. JOURNAL OF EXPERIMENTAL MEDICINE
- IFN- Attenuates Hypoxia-Inducible Factor (HIF) Activity in Intestinal Epithelial Cells through Transcriptional Repression of HIF-1
- (2011) L. E. Glover et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: Distinct Glycolytic and Lipid Oxidative Metabolic Programs Are Essential for Effector and Regulatory CD4+ T Cell Subsets
- (2011) R. D. Michalek et al. JOURNAL OF IMMUNOLOGY
- MCM Proteins Are Negative Regulators of Hypoxia-Inducible Factor 1
- (2011) Maimon E. Hubbi et al. MOLECULAR CELL
- Tumour hypoxia promotes tolerance and angiogenesis via CCL28 and Treg cells
- (2011) Andrea Facciabene et al. NATURE
- The transcription factors Blimp-1 and IRF4 jointly control the differentiation and function of effector regulatory T cells
- (2011) Erika Cretney et al. NATURE IMMUNOLOGY
- Ischemia and reperfusion—from mechanism to translation
- (2011) Holger K Eltzschig et al. NATURE MEDICINE
- Follicular regulatory T cells expressing Foxp3 and Bcl-6 suppress germinal center reactions
- (2011) Yeonseok Chung et al. NATURE MEDICINE
- Foxp3+ follicular regulatory T cells control the germinal center response
- (2011) Michelle A Linterman et al. NATURE MEDICINE
- Principles and mechanisms of vessel normalization for cancer and other angiogenic diseases
- (2011) Peter Carmeliet et al. NATURE REVIEWS DRUG DISCOVERY
- Hypoxia and Inflammation
- (2011) Holger K. Eltzschig et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oxygen Sensing, Homeostasis, and Disease
- (2011) Gregg L. Semenza NEW ENGLAND JOURNAL OF MEDICINE
- Invited review: decoding the microRNA response to hypoxia
- (2011) Roger Pocock PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY
- Type 1 regulatory T cells (Tr1) in autoimmunity
- (2011) Caroline Pot et al. SEMINARS IN IMMUNOLOGY
- The Hydroxylase Inhibitor Dimethyloxallyl Glycine Attenuates Endotoxic Shock Via Alternative Activation of Macrophages and IL-10 Production by B1 Cells
- (2011) Emily Hams et al. SHOCK
- Macrophage Expression of Hypoxia-Inducible Factor-1 Suppresses T-Cell Function and Promotes Tumor Progression
- (2010) A. L. Doedens et al. CANCER RESEARCH
- Regulation of the HIF-1α Level Is Essential for Hematopoietic Stem Cells
- (2010) Keiyo Takubo et al. Cell Stem Cell
- Metabolism in T cell activation and differentiation
- (2010) Erika L Pearce CURRENT OPINION IN IMMUNOLOGY
- Epigenetics: The epicenter of the hypoxic response
- (2010) Jenny A. Watson et al. Epigenetics
- Differential activation and antagonistic function of HIF- isoforms in macrophages are essential for NO homeostasis
- (2010) N. Takeda et al. GENES & DEVELOPMENT
- The metabolic life and times of a T-cell
- (2010) Ryan D. Michalek et al. IMMUNOLOGICAL REVIEWS
- Hypoxia-inducible factor 2α regulates macrophage function in mouse models of acute and tumor inflammation
- (2010) Hongxia Z. Imtiyaz et al. JOURNAL OF CLINICAL INVESTIGATION
- HIF-1α regulates function and differentiation of myeloid-derived suppressor cells in the tumor microenvironment
- (2010) Cesar A. Corzo et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Hydroxylase Inhibition Abrogates TNF- -Induced Intestinal Epithelial Damage by Hypoxia-Inducible Factor-1-Dependent Repression of FADD
- (2010) P. Hindryckx et al. JOURNAL OF IMMUNOLOGY
- Inhibition of Prolyl Hydroxylases Increases Erythropoietin Production in ESRD
- (2010) W. M. Bernhardt et al. JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY
- Hypoxia: an alarm signal during intestinal inflammation
- (2010) Sean P. Colgan et al. Nature Reviews Gastroenterology & Hepatology
- How does PKMζ maintain long-term memory?
- (2010) Todd C. Sacktor NATURE REVIEWS NEUROSCIENCE
- Ancient Atmospheres and the Evolution of Oxygen Sensing Via the Hypoxia-Inducible Factor in Metazoans
- (2010) Cormac T. Taylor et al. PHYSIOLOGY
- Hypoxia-induced changes in pulmonary and systemic vascular resistance: Where is the O2 sensor?
- (2010) Gregory B. Waypa et al. RESPIRATORY PHYSIOLOGY & NEUROBIOLOGY
- The Role of NF-κB in Hypoxia-Induced Gene Expression
- (2009) Cormac T. Taylor et al. Annals of the New York Academy of Sciences
- Role of Hypoxia-Inducible Factor 1α in T Cells as a Negative Regulator in Development of Vascular Remodeling
- (2009) Hirotsugu Kurobe et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Prolyl hydroxylases as regulators of cell metabolism: Figure 1
- (2009) Houda Boulahbel et al. BIOCHEMICAL SOCIETY TRANSACTIONS
- Mitochondrial reactive oxygen species regulate hypoxic signaling
- (2009) Robert B Hamanaka et al. CURRENT OPINION IN CELL BIOLOGY
- HIF-1 Inhibitors for Cancer Therapy: From Gene Expression to Drug Discovery
- (2009) G. Semenza CURRENT PHARMACEUTICAL DESIGN
- Enhanced Interferon-γ Gene Expression in T Cells and Reduced Ovalbumin-Dependent Lung Eosinophilia in Hypoxia-Inducible Factor-1-α-Deficient Mice
- (2009) Jia Guo et al. INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY
- Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
- (2009) David R. Mole et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The Cooperative Induction of Hypoxia-Inducible Factor-1 and STAT3 during Hypoxia Induced an Impairment of Tumor Susceptibility to CTL-Mediated Cell Lysis
- (2009) M. Z. Noman et al. JOURNAL OF IMMUNOLOGY
- Induction of HIF-1α and the glycolytic pathway alters apoptotic and differentiation profiles of activated human T cells
- (2009) Anis Larbi et al. JOURNAL OF LEUKOCYTE BIOLOGY
- Adaptation of Human CD4+ T Cells to Pathophysiological Hypoxia: A Transcriptome Analysis
- (2009) T. GABER et al. JOURNAL OF RHEUMATOLOGY
- Regulatory T-cell suppressor program co-opts transcription factor IRF4 to control TH2 responses
- (2009) Ye Zheng et al. NATURE
- The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation
- (2009) Meghan A Koch et al. NATURE IMMUNOLOGY
- Lean, but not obese, fat is enriched for a unique population of regulatory T cells that affect metabolic parameters
- (2009) Markus Feuerer et al. NATURE MEDICINE
- CD8+ effector T cells contribute to macrophage recruitment and adipose tissue inflammation in obesity
- (2009) Satoshi Nishimura et al. NATURE MEDICINE
- Normalization of obesity-associated insulin resistance through immunotherapy
- (2009) Shawn Winer et al. NATURE MEDICINE
- Inhibition of oxygen sensors as a therapeutic strategy for ischaemic and inflammatory disease
- (2009) Peter Fraisl et al. NATURE REVIEWS DRUG DISCOVERY
- Regulation of Oxygen Homeostasis by Hypoxia-Inducible Factor 1
- (2009) Gregg L. Semenza PHYSIOLOGY
- Acriflavine inhibits HIF-1 dimerization, tumor growth, and vascularization
- (2009) K. Lee et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- CD4+ Regulatory T Cells Control TH17 Responses in a Stat3-Dependent Manner
- (2009) A. Chaudhry et al. SCIENCE
- The aryl hydrocarbon receptor in immunity
- (2009) Charlotte Esser et al. TRENDS IN IMMUNOLOGY
- Epidermal Sensing of Oxygen Is Essential for Systemic Hypoxic Response
- (2008) Adam T. Boutin et al. CELL
- Human CD4+ T cells maintain specific functions even under conditions of extremely restricted ATP production
- (2008) Robert Tripmacher et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Hypoxia controls CD4+CD25+ regulatory T-cell homeostasis via hypoxia-inducible factor-1α
- (2008) Jeremy Ben-Shoshan et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Hypoxia-Independent Activation of HIF-1 by Enterobacteriaceae and Their Siderophores
- (2008) Hanna Hartmann et al. GASTROENTEROLOGY
- Preferential expression of the novel alternative isoform I.3 of hypoxia-inducible factor 1α in activated human T lymphocytes
- (2008) Dmitriy Lukashev et al. HUMAN IMMUNOLOGY
- Tuberculous Granulomas Are Hypoxic in Guinea Pigs, Rabbits, and Nonhuman Primates
- (2008) L. E. Via et al. INFECTION AND IMMUNITY
- Emerging role of adipose tissue hypoxia in obesity and insulin resistance
- (2008) J Ye INTERNATIONAL JOURNAL OF OBESITY
- Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
- (2008) William G. Kaelin et al. MOLECULAR CELL
- NF-κB links innate immunity to the hypoxic response through transcriptional regulation of HIF-1α
- (2008) Jordi Rius et al. NATURE
- Digoxin and other cardiac glycosides inhibit HIF-1 synthesis and block tumor growth
- (2008) H. Zhang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Mitochondria and cellular oxygen sensing in the HIF pathway
- (2007) Cormac T. Taylor BIOCHEMICAL JOURNAL
- The Hydroxylase Inhibitor Dimethyloxalylglycine Is Protective in a Murine Model of Colitis
- (2007) Eoin P. Cummins et al. GASTROENTEROLOGY
- Mucosal Protection by Hypoxia-Inducible Factor Prolyl Hydroxylase Inhibition
- (2007) Andreas Robinson et al. GASTROENTEROLOGY
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