Role of metabolism in cancer cell radioresistance and radiosensitization methods

Circular RNAs (circRNAs) in cancer

(2018) Ruoyu Zhou et al.   CANCER LETTERS

Function of the c-Met receptor tyrosine kinase in carcinogenesis and associated therapeutic opportunities

(2018) Yazhuo Zhang et al.   Molecular Cancer

LncRNAs regulate the cytoskeleton and related Rho/ROCK signaling in cancer metastasis

(2018) Yanyan Tang et al.   Molecular Cancer

Circular RNAs function as ceRNAs to regulate and control human cancer progression

(2018) Yaxian Zhong et al.   Molecular Cancer

BPIFB1 (LPLUNC1) inhibits radioresistance in nasopharyngeal carcinoma by inhibiting VTN expression

(2018) Fang Wei et al.   Cell Death & Disease

Long non-coding RNA PVT1 predicts poor prognosis and induces radioresistance by regulating DNA repair and cell apoptosis in nasopharyngeal carcinoma

(2018) Yi He et al.   Cell Death & Disease

Roles of Long Noncoding RNAs in Recurrence and Metastasis of Radiotherapy-Resistant Cancer Stem Cells

(2017) Hsiang-Cheng Chi et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2-Methoxyestradiol enhances radiosensitivity in radioresistant melanoma MDA-MB-435R cells by regulating glycolysis via HIF-1α/PDK1 axis

(2017) Hong Zhao et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Autophagy enhanced the radioresistance of non-small cell lung cancer by regulating ROS level under hypoxia condition

(2017) Xiaoyan Chen et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Silencing the Girdin gene enhances radio-sensitivity of hepatocellular carcinoma via suppression of glycolytic metabolism

(2017) Li Yu et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

circGFRA1 and GFRA1 act as ceRNAs in triple negative breast cancer by regulating miR-34a

(2017) Rongfang He et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

The CD44 standard isoform contributes to radioresistance of pancreatic cancer cells

(2017) Kento Tsubouchi et al.   JOURNAL OF RADIATION RESEARCH

Acquisition of radioresistance by IL-6 treatment is caused by suppression of oxidative stress derived from mitochondria after γ-irradiation

(2017) Yuki Tamari et al.   JOURNAL OF RADIATION RESEARCH

Genome-Wide Analysis of 18 Epstein-Barr Viruses Isolated from Primary Nasopharyngeal Carcinoma Biopsy Specimens

(2017) Chaofeng Tu et al.   JOURNAL OF VIROLOGY

Low Rap1-interacting factor 1 and sirtuin 6 expression predict poor outcome in radiotherapy-treated Hodgkin lymphoma patients

(2017) Hamid Bur et al.   LEUKEMIA & LYMPHOMA

Role of long non-coding RNAs in glucose metabolism in cancer

(2017) Chunmei Fan et al.   Molecular Cancer

Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer

(2017) Yanyan Tang et al.   Molecular Cancer

14-3-3σ Contributes to Radioresistance By Regulating DNA Repair and Cell Cycle via PARP1 and CHK2

(2017) Yifan Chen et al.   MOLECULAR CANCER RESEARCH

Tumor cell-derived lactate induces TAZ-dependent upregulation of PD-L1 through GPR81 in human lung cancer cells

(2017) J Feng et al.   ONCOGENE

Berberine sensitizes nasopharyngeal carcinoma cells to radiation through inhibition of Sp1 and EMT

(2017) Jun Wang et al.   ONCOLOGY REPORTS

Trend analysis of cancer incidence and mortality in China

(2017) Fang Wei et al.   Science China-Life Sciences

miR-668 enhances the radioresistance of human breast cancer cell by targeting IκBα

(2017) Ming Luo et al.   Breast Cancer

CD44+CD24+ subset of PANC-1 cells exhibits radiation resistance via decreased levels of reactive oxygen species

(2017) Lei Wang et al.   Oncology Letters

p38 MAPK signaling and phosphorylations in the BRCT1 domain regulate XRCC1 recruitment to sites of DNA damage

(2017) Mirta Mittelstedt Leal de Sousa et al.   Scientific Reports

Impact of CD44 expression on radiation response for bladder cancer

(2017) Chun-Te Wu et al.   Journal of Cancer

SIRT1 Enhances the Survival of Human Embryonic Stem Cells by Promoting DNA Repair

(2017) Jiho Jang et al.   Stem Cell Reports

Hypoxia-induced angiotensin II by the lactate-chymase-dependent mechanism mediates radioresistance of hypoxic tumor cells

(2017) Guozhu Xie et al.   Scientific Reports

UCHL1-HIF-1 axis-mediated antioxidant property of cancer cells as a therapeutic target for radiosensitization

(2017) Ryota Nakashima et al.   Scientific Reports

Metformin Has a Positive Therapeutic Effect on Prostate Cancer in Patients With Type 2 Diabetes Mellitus

(2016) R. William Chong et al.   AMERICAN JOURNAL OF THE MEDICAL SCIENCES

Mitochondrial drug targets in neurodegenerative diseases

(2016) Jiyoun Lee   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Inhibition of Glut1 by WZB117 sensitizes radioresistant breast cancer cells to irradiation

(2016) Fei Zhao et al.   CANCER CHEMOTHERAPY AND PHARMACOLOGY

Shared Risk Factors in Cardiovascular Disease and Cancer

(2016) Ryan J. Koene et al.   CIRCULATION

Lactate as a predictive marker for tumor recurrence in patients with head and neck squamous cell carcinoma (HNSCC) post radiation: a prospective study over 15 years

(2016) Sebastian Blatt et al.   Clinical Oral Investigations

Hypoxia-inducible proteins HIF1α and lactate dehydrogenase LDH5, key markers of anaerobic metabolism, relate with stem cell markers and poor post-radiotherapy outcome in bladder cancer

(2016) Michael I. Koukourakis et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

The Involvement of Mitochondrial Membrane Potential in Cross-Resistance Between Radiation and Docetaxel

(2016) Yoshikazu Kuwahara et al.   INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS

MicroRNA-19b-3p regulates nasopharyngeal carcinoma radiosensitivity by targeting TNFAIP3/NF-κB axis

(2016) Teng Huang et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Targeting autophagy to sensitive glioma to temozolomide treatment

(2016) Yuanliang Yan et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Hypoxia-inducible factor 1–mediated characteristic features of cancer cells for tumor radioresistance

(2016) Hiroshi Harada   JOURNAL OF RADIATION RESEARCH

Fractionated irradiation-induced EMT-like phenotype conferred radioresistance in esophageal squamous cell carcinoma

(2016) Hongfang Zhang et al.   JOURNAL OF RADIATION RESEARCH

The flavonoid apigenin reduces prostate cancer CD44 + stem cell survival and migration through PI3K/Akt/NF-κB signaling

(2016) Suat Erdogan et al.   LIFE SCIENCES

Oxidative stress and metabolic disorders: Pathogenesis and therapeutic strategies

(2016) Vibha Rani et al.   LIFE SCIENCES

Extensive metabolic disorders are present in APCmin tumorigenesis mice

(2016) Zhenzhen Liu et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Sensitization of hepatocellular carcinoma cells to irradiation by miR-34a through targeting lactate dehydrogenase-A

(2016) XIAOGANG LI et al.   Molecular Medicine Reports

CXCL12 mediates glioblastoma resistance to radiotherapy in the subventricular zone

(2016) Nicolas Goffart et al.   NEURO-ONCOLOGY

2-Methoxyestradiol inhibits the proliferation and migration and reduces the radioresistance of nasopharyngeal carcinoma CNE-2 stem cells via NF-κB/HIF-1 signaling pathway inactivation and EMT reversal

(2016) Shun-Long Wu et al.   ONCOLOGY REPORTS

Investigating the Radioresistant Properties of Lung Cancer Stem Cells in the Context of the Tumor Microenvironment

(2016) Ryan Chan et al.   RADIATION RESEARCH

MiR-21 modulates radiosensitivity of cervical cancer through inhibiting autophagy via the PTEN/Akt/HIF-1α feedback loop and the Akt-mTOR signaling pathway

(2016) Lili Song et al.   TUMOR BIOLOGY

Knockdown of the M2 Isoform of Pyruvate Kinase (PKM2) with shRNA Enhances the Effect of Docetaxel in Human NSCLC Cell LinesIn Vitro

(2016) Sujuan Yuan et al.   YONSEI MEDICAL JOURNAL

Overexpression of microRNA-133b sensitizes non-small cell lung cancer cells to irradiation through the inhibition of glycolysis

(2016) GANG LIU et al.   Oncology Letters

Radiation induces the generation of cancer stem cells: A novel mechanism for cancer radioresistance

(2016) Fengsheng Li et al.   Oncology Letters

Docetaxel induced-JNK2/PHD1 signaling pathway increases degradation of HIF-1α and causes cancer cell death under hypoxia

(2016) Eun-Taex Oh et al.   Scientific Reports

Hypoxia-responsive miR-124 and miR-144 reduce hypoxia-induced autophagy and enhance radiosensitivity of prostate cancer cells via suppressing PIM1

(2016) Hao Gu et al.   Cancer Medicine

Transient elevation of glycolysis confers radio-resistance by facilitating DNA repair in cells

(2015) Anant Narayan Bhatt et al.   BMC CANCER

Radiosensitization with combined use of olaparib and PI-103 in triple-negative breast cancer

(2015) Na Young Jang et al.   BMC CANCER

Targeting pyruvate kinase M2 contributes to radiosensitivity of non-small cell lung cancer cells in vitro and in vivo

(2015) Mao-Bin Meng et al.   CANCER LETTERS

Therapeutic strategies targeting cancer stem cells

(2015) Go J. Yoshida et al.   CANCER SCIENCE

Reprogramming of glucose, fatty acid and amino acid metabolism for cancer progression

(2015) Zhaoyong Li et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Metformin reduces ovarian cancer risk in Taiwanese women with type 2 diabetes mellitus

(2015) Chin-Hsiao Tseng   DIABETES-METABOLISM RESEARCH AND REVIEWS

The acquired radioresistance in HeLa cells under conditions mimicking hypoxia was attenuated by a decreased expression of HIF subunit genes induced by RNA interference

(2015) Nobutaka Doi et al.   EXPERIMENTAL CELL RESEARCH

PI3K/mTOR pathway inhibition overcomes radioresistance via suppression of the HIF1-α/VEGF pathway in endometrial cancer

(2015) Aki Miyasaka et al.   GYNECOLOGIC ONCOLOGY

Metabolic reprogramming: the emerging concept and associated therapeutic strategies

(2015) Go J. Yoshida   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Paclitaxel pretreatment overcomes hypoxia inducible factor-1α-induced radioresistance acquisition of human hepatoma and lung adenocarcinoma cells

(2015) Kun-Goung Lai et al.   LIFE SCIENCES

Acute Tumor Lactate Perturbations as a Biomarker of Genotoxic Stress: Development of a Biochemical Model

(2015) V. C. Sandulache et al.   MOLECULAR CANCER THERAPEUTICS

CDK1-Mediated SIRT3 Activation Enhances Mitochondrial Function and Tumor Radioresistance

(2015) R. Liu et al.   MOLECULAR CANCER THERAPEUTICS

Sensitization of Glioblastoma Cells to Irradiation by Modulating the Glucose Metabolism

(2015) H. Shen et al.   MOLECULAR CANCER THERAPEUTICS

Apigenin inhibits the proliferation of adenoid cystic carcinoma via suppression of glucose transporter-1

(2015) JIN FANG et al.   Molecular Medicine Reports

Proteomic overview and perspectives of the radiation-induced bystander effects

(2015) François Chevalier et al.   MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH

Targeting mitochondria metabolism for cancer therapy

(2015) Samuel E Weinberg et al.   Nature Chemical Biology

Breast cancer therapy-associated cardiovascular disease

(2015) Timothy M. Zagar et al.   Nature Reviews Clinical Oncology

Metformin Use Is Associated With Better Survival of Breast Cancer Patients With Diabetes: A Meta-Analysis

(2015) H. Xu et al.   ONCOLOGIST

MicroRNA-216a enhances the radiosensitivity of pancreatic cancer cells by inhibiting beclin-1-mediated autophagy

(2015) XIANGLIANG ZHANG et al.   ONCOLOGY REPORTS

Inhibiting GLUT-1 expression and PI3K/Akt signaling using apigenin improves the radiosensitivity of laryngeal carcinoma in vivo

(2015) YANG-YANG BAO et al.   ONCOLOGY REPORTS

Epithelial–mesenchymal transition in human cancer: Comprehensive reprogramming of metabolism, epigenetics, and differentiation

(2015) Linna Li et al.   PHARMACOLOGY & THERAPEUTICS

The NG2 Proteoglycan Protects Oligodendrocyte Precursor Cells against Oxidative Stress via Interaction with OMI/HtrA2

(2015) Frank Maus et al.   PLoS One

The expression level of the transcription factor Aryl hydrocarbon receptor nuclear translocator (ARNT) determines cellular survival after radiation treatment

(2015) Markus Mandl et al.   Radiation Oncology

The role of hypoxia-inducible factor-1α in radiation-induced autophagic cell death in breast cancer cells

(2015) Rui Zhong et al.   TUMOR BIOLOGY

Hypoxia-Inducible Factor-1α Protects Cervical Carcinoma Cells from Apoptosis Induced by Radiation via Modulation of Vascular Endothelial Growth Factor and p53 under Hypoxia

(2015) Fengmei Wang   MEDICAL SCIENCE MONITOR

Co-Inhibition of GLUT-1 Expression and the PI3K/Akt Signaling Pathway to Enhance the Radiosensitivity of Laryngeal Carcinoma Xenografts In Vivo

(2015) Xing-Mei Luo et al.   PLoS One

Reprogramming of tumor metabolism by targeting mitochondria improves tumor response to irradiation

(2014) Vanesa Bol et al.   ACTA ONCOLOGICA

The role of melanogenesis in regulation of melanoma behavior: Melanogenesis leads to stimulation of HIF-1α expression and HIF-dependent attendant pathways

(2014) A. Slominski et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

Overcoming 5-Fu Resistance of Colon Cells through Inhibition of Glut1 by the Specific Inhibitor WZB117

(2014) Wei Liu et al.   Asian Pacific Journal of Cancer Prevention

Modulatory roles of glycolytic enzymes in cell death

(2014) Claudia Cerella et al.   BIOCHEMICAL PHARMACOLOGY

Lactate dehydrogenase 5 isoenzyme overexpression defines resistance of prostate cancer to radiotherapy

(2014) M I Koukourakis et al.   BRITISH JOURNAL OF CANCER

Stereotactic ablative body radiotherapy combined with immunotherapy: Present status and future perspectives

(2014) N.H. Rekers et al.   Cancer Radiotherapie

IGF2 Preserves Osteosarcoma Cell Survival by Creating an Autophagic State of Dormancy That Protects Cells against Chemotherapeutic Stress

(2014) T. Shimizu et al.   CANCER RESEARCH

AKT1 and MYC Induce Distinctive Metabolic Fingerprints in Human Prostate Cancer

(2014) C. Priolo et al.   CANCER RESEARCH

Mitochondrial MKP1 Is a Target for Therapy-Resistant HER2-Positive Breast Cancer Cells

(2014) D. Candas et al.   CANCER RESEARCH

Osteopontin-CD44 Signaling in the Glioma Perivascular Niche Enhances Cancer Stem Cell Phenotypes and Promotes Aggressive Tumor Growth

(2014) Alexander Pietras et al.   Cell Stem Cell

Diabetes mellitus: influences on cancer risk

(2014) Leszek Szablewski   DIABETES-METABOLISM RESEARCH AND REVIEWS

Knockdown of miR-210 decreases hypoxic glioma stem cells stemness and radioresistance

(2014) Wei Yang et al.   EXPERIMENTAL CELL RESEARCH

Hypoxia-induced autophagy reduces radiosensitivity by the HIF-1α/miR-210/Bcl-2 pathway in colon cancer cells

(2014) YONG SUN et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hypoxia sustains glioblastoma radioresistance through ERKs/DNA-PKcs/HIF-1α functional interplay

(2014) FRANCESCO MARAMPON et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Hypoxia as a biomarker for radioresistant cancer stem cells

(2014) Claudia Peitzsch et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Cancer stem cells and radioresistance

(2014) Kiera Rycaj et al.   INTERNATIONAL JOURNAL OF RADIATION BIOLOGY

Hypoxia-induced autophagy contributes to radioresistance via c-Jun-mediated Beclin1 expression in lung cancer cells

(2014) Yan-mei Zou et al.   Journal of Huazhong University of Science and Technology-Medical Sciences

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(2014) Markus Mandl et al.   MOLECULAR MEDICINE

Roles of glucose transporter-1 and the phosphatidylinositol 3-kinase/protein kinase B pathway in cancer radioresistance (Review)

(2014) JIN FANG et al.   Molecular Medicine Reports

Mitochondrial KATP Channels Control Glioma Radioresistance by Regulating ROS-Induced ERK Activation

(2014) Lianyan Huang et al.   MOLECULAR NEUROBIOLOGY

Oncogene ablation-resistant pancreatic cancer cells depend on mitochondrial function

(2014) Andrea Viale et al.   NATURE

Altered Mitochondrial Function and Energy Metabolism Is Associated with a Radioresistant Phenotype in Oesophageal Adenocarcinoma

(2014) Niamh Lynam-Lennon et al.   PLoS One

Loss of the tumor suppressor LKB1 promotes metabolic reprogramming of cancer cells via HIF-1 

(2014) B. Faubert et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

AKT-mediated enhanced aerobic glycolysis causes acquired radioresistance by human tumor cells

(2014) Tsutomu Shimura et al.   RADIOTHERAPY AND ONCOLOGY

STAT3 inhibitor NSC74859 radiosensitizes esophageal cancer via the downregulation of HIF-1α

(2014) Chi Zhang et al.   TUMOR BIOLOGY

STAT3 inhibitor stattic enhances radiosensitivity in esophageal squamous cell carcinoma

(2014) Qu Zhang et al.   TUMOR BIOLOGY

PI3K/Akt/mTOR pathway inhibitors enhance radiosensitivity in radioresistant prostate cancer cells through inducing apoptosis, reducing autophagy, suppressing NHEJ and HR repair pathways

(2014) L Chang et al.   Cell Death & Disease

Berberine radiosensitizes human nasopharyngeal carcinoma by suppressing hypoxia-inducible factor-1α expression

(2013) Chi Zhang et al.   ACTA OTO-LARYNGOLOGICA

Inversed relationship between CD44 variant and c-Myc due to oxidative stress-induced canonical Wnt activation

(2013) Go J. Yoshida et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Progress and controversies: Radiation therapy for invasive breast cancer

(2013) Reshma Jagsi   CA-A CANCER JOURNAL FOR CLINICIANS

Therapeutic strategies targeting cancer stem cells

(2013) Xiaoyan Ning et al.   CANCER BIOLOGY & THERAPY

Chrysin enhances sensitivity of BEL-7402/ADM cells to doxorubicin by suppressing PI3K/Akt/Nrf2 and ERK/Nrf2 pathway

(2013) Ai-Mei Gao et al.   CHEMICO-BIOLOGICAL INTERACTIONS

Effect of Antisense Oligodeoxynucleotides Glucose Transporter-1 on Enhancement of Radiosensitivity of Laryngeal Carcinoma

(2013) Sen-Xiang Yan et al.   International Journal of Medical Sciences

Glucose Transporter-1 as a New Therapeutic Target in Laryngeal Carcinoma

(2013) X-M Luo et al.   JOURNAL OF INTERNATIONAL MEDICAL RESEARCH

Mitochondrial protein ATPase family, AAA domain containing 3A correlates with radioresistance in glioblastoma

(2013) W.-C. You et al.   NEURO-ONCOLOGY

Autophagy in Human Health and Disease

(2013)   NEW ENGLAND JOURNAL OF MEDICINE

IGF1 Receptor Signaling Regulates Adaptive Radioprotection in Glioma Stem Cells

(2013) Satoru Osuka et al.   STEM CELLS

HDAC inhibitors reverse acquired radio resistance of KYSE-150R esophageal carcinoma cells by modulating Bmi-1 expression

(2013) Qinghua Dong et al.   TOXICOLOGY LETTERS

MiR-210 promotes a hypoxic phenotype and increases radioresistance in human lung cancer cell lines

(2013) S Grosso et al.   Cell Death & Disease

Obesity Promotes Liver Carcinogenesis via Mcl-1 Stabilization Independent of IL-6Rα Signaling

(2013) Sabine Gruber et al.   Cell Reports

KNK437, abrogates hypoxia-induced radioresistance by dual targeting of the AKT and HIF-1α survival pathways

(2012) Deepu Oommen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Li-Fraumeni syndrome with simultaneous osteosarcoma and liver cancer: Increased expression of a CD44 variant isoform after chemotherapy

(2012) Go J Yoshida et al.   BMC CANCER

The hypoxic microenvironment upgrades stem-like properties of ovarian cancer cells

(2012) Dongming Liang et al.   BMC CANCER

Targeting Hypoxia, HIF-1, and Tumor Glucose Metabolism to Improve Radiotherapy Efficacy

(2012) T. W. H. Meijer et al.   CLINICAL CANCER RESEARCH

Downregulation of miR-210 expression inhibits proliferation, induces apoptosis and enhances radiosensitivity in hypoxic human hepatoma cells in vitro

(2012) Wei Yang et al.   EXPERIMENTAL CELL RESEARCH

The critical role of mast cell-derived hypoxia-inducible factor-1α in human and mice melanoma growth

(2012) Hyun-Ja Jeong et al.   INTERNATIONAL JOURNAL OF CANCER

Crystal structure of a bacterial homologue of glucose transporters GLUT1–4

(2012) Linfeng Sun et al.   NATURE

Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell

(2012) Toshifumi Yae et al.   Nature Communications

Terfenadine induces apoptosis and autophagy in melanoma cells through ROS-dependent and -independent mechanisms

(2011) Francesca Nicolau-Galmés et al.   APOPTOSIS

Chk2-mediated G2/M cell cycle arrest maintains radiation resistance in malignant meningioma cells

(2011) Venkateswara Rao Gogineni et al.   CANCER LETTERS

Lactate: A Metabolic Key Player in Cancer

(2011) F. Hirschhaeuser et al.   CANCER RESEARCH

Reduction of nitric oxide level enhances the radiosensitivity of hypoxic non-small cell lung cancer

(2011) Wael Saleem et al.   CANCER SCIENCE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

Targeting cancer metabolism – aiming at a tumour's sweet-spot

(2011) Neil P. Jones et al.   DRUG DISCOVERY TODAY

The monocarboxylate transporter family-Structure and functional characterization

(2011) Andrew P. Halestrap   IUBMB LIFE

HIF-1α inhibition by siRNA or chetomin in human malignant glioma cells: effects on hypoxic radioresistance and monitoring via CA9 expression

(2010) Jacqueline Kessler et al.   BMC CANCER

Mitochondria-targeted antioxidant enzyme activity regulates radioresistance in human pancreatic cancer cells

(2010) Carolyn J. Fisher et al.   CANCER BIOLOGY & THERAPY

Sorafenib induces preferential apoptotic killing of a drug- and radio-resistant hep G2 cells through a mitochondria-dependent oxidative stress mechanism

(2010) Jeng-Fong Chiou et al.   CANCER BIOLOGY & THERAPY

CD44 Expression Predicts Local Recurrence after Radiotherapy in Larynx Cancer

(2010) M. C. de Jong et al.   CLINICAL CANCER RESEARCH

HIF-1 and NDRG2 contribute to hypoxia-induced radioresistance of cervical cancer Hela cells

(2010) Junye Liu et al.   EXPERIMENTAL CELL RESEARCH

Apigenin Down-Regulates the Hypoxia Response Genes: HIF-1α, GLUT-1, and VEGF in Human Pancreatic Cancer Cells

(2010) Laleh G. Melstrom et al.   JOURNAL OF SURGICAL RESEARCH

GLUT1 gene is a potential hypoxic marker in colorectal cancer patients

(2009) Fu-Yen Chung et al.   BMC CANCER

STAT1-dependent expression of energy metabolic pathways links tumour growth and radioresistance to the Warburg effect

(2009) Sean P Pitroda et al.   BMC Medicine

Inhibition of cell proliferation and glucose uptake in human laryngeal carcinoma cells by antisense oligonucleotides against glucose transporter-1

(2009) Shui-Hong Zhou et al.   HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK

Lactate Dehydrogenase 5 Expression in Squamous Cell Head and Neck Cancer Relates to Prognosis following Radical or Postoperative Radiotherapy

(2009) Michael I. Koukourakis et al.   ONCOLOGY

Glycolytic metabolism and tumour response to fractionated irradiation

(2009) Ulrike G.A. Sattler et al.   RADIOTHERAPY AND ONCOLOGY

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Histone Deacetylase Inhibition and Blockade of the Glycolytic Pathway Synergistically Induce Glioblastoma Cell Death

(2008) V. Egler et al.   CLINICAL CANCER RESEARCH