Abnormal X chromosome inactivation and tumor development

X chromosome inactivation in human development

(2020) Catherine Patrat et al.   DEVELOPMENT

Emerging role of tumor-related functional peptides encoded by lncRNA and circRNA

(2020) Pan Wu et al.   Molecular Cancer

Predictive biomarkers and mechanisms underlying resistance to PD1/PD-L1 blockade cancer immunotherapy

(2020) Daixi Ren et al.   Molecular Cancer

Analysis of status and countermeasures of cancer incidence and mortality in China

(2019) Chunchun Wu et al.   Science China-Life Sciences

Xist Deletional Analysis Reveals an Interdependency between Xist RNA and Polycomb Complexes for Spreading along the Inactive X

(2019) David Colognori et al.   MOLECULAR CELL

Effects and mechanisms of innate immune molecules on inhibiting nasopharyngeal carcinoma

(2019) Fang Xiong et al.   CHINESE MEDICAL JOURNAL

circ MAN 1A2 could serve as a novel serum biomarker for malignant tumors

(2019) Chun‐Mei Fan et al.   CANCER SCIENCE

TSC22D2 identified as a candidate susceptibility gene of multi-cancer pedigree using genome-wide linkage analysis and whole exome sequencing

(2019) Lan Xiao et al.   CARCINOGENESIS

Long non-coding RNA PVT1 interacts with MYC and its downstream molecules to synergistically promote tumorigenesis

(2019) Ke Jin et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

PVT1 Promotes Cancer Progression via MicroRNAs

(2019) Wenxi Wang et al.   Frontiers in Oncology

Neoantigen vaccine: an emerging tumor immunotherapy

(2019) Miao Peng et al.   Molecular Cancer

XIST-Promoter Demethylation as Tissue Biomarker for Testicular Germ Cell Tumors and Spermatogenesis Quality

(2019) Lobo et al.   Cancers

Loss of XIST in Breast Cancer Activates MSN-c-Met and Reprograms Microglia via Exosomal miRNA to Promote Brain Metastasis

(2018) Fei Xing et al.   CANCER RESEARCH

UTX is an escape from X-inactivation tumor-suppressor in B cell lymphoma

(2018) Xiaoxi Li et al.   Nature Communications

Identification of genomic alterations in nasopharyngeal carcinoma and nasopharyngeal carcinoma-derived Epstein–Barr virus by whole-genome sequencing

(2018) Chaofeng Tu et al.   CARCINOGENESIS

Effects of tumor metabolic microenvironment on regulatory T cells

(2018) Yi-an Wang et al.   Molecular Cancer

Application of atomic force microscopy in cancer research

(2018) Xiangying Deng et al.   JOURNAL OF NANOBIOTECHNOLOGY

Role of long non-coding RNAs in glucose metabolism in cancer

(2017) Chunmei Fan et al.   Molecular Cancer

Linking long non-coding RNAs and SWI/SNF complexes to chromatin remodeling in cancer

(2017) Yanyan Tang et al.   Molecular Cancer

Trend analysis of cancer incidence and mortality in China

(2017) Fang Wei et al.   Science China-Life Sciences

High Expression of LINC01420 indicates an unfavorable prognosis and modulates cell migration and invasion in nasopharyngeal carcinoma

(2017) Liting Yang et al.   Journal of Cancer

Control of Chromosomal Localization of Xist by hnRNP U Family Molecules

(2016) Takehisa Sakaguchi et al.   DEVELOPMENTAL CELL

Structural organization of the inactive X chromosome in the mouse

(2016) Luca Giorgetti et al.   NATURE

Tumor-suppressor genes that escape from X-inactivation contribute to cancer sex bias

(2016) Andrew Dunford et al.   NATURE GENETICS

Xist recruits the X chromosome to the nuclear lamina to enable chromosome-wide silencing

(2016) C.-K. Chen et al.   SCIENCE

Mutations in DDX3X Are a Common Cause of Unexplained Intellectual Disability with Gender-Specific Effects on Wnt Signaling

(2015) Lot Snijders Blok et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Systematic Discovery of Xist RNA Binding Proteins

(2015) Ci Chu et al.   CELL

The inactive X chromosome is epigenetically unstable and transcriptionally labile in breast cancer

(2015) Ronan Chaligné et al.   GENOME RESEARCH

The Xist lncRNA interacts directly with SHARP to silence transcription through HDAC3

(2015) Colleen A. McHugh et al.   NATURE

A Pooled shRNA Screen Identifies Rbm15, Spen, and Wtap as Factors Required for Xist RNA-Mediated Silencing

(2015) Benoit Moindrot et al.   Cell Reports

Escape from X Inactivation Varies in Mouse Tissues

(2015) Joel B. Berletch et al.   PLoS Genetics

The H3K27me3 demethylase UTX is a gender-specific tumor suppressor in T-cell acute lymphoblastic leukemia

(2014) Joni Van der Meulen et al.   BLOOD

A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping

(2014) Suhas S.P. Rao et al.   CELL

X-chromosome inactivation in development and cancer

(2014) Ronan Chaligné et al.   FEBS LETTERS

Human UTY(KDM6C) Is a Male-specificNϵ-Methyl Lysyl Demethylase

(2014) Louise J. Walport et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mammalian Y chromosomes retain widely expressed dosage-sensitive regulators

(2014) Daniel W. Bellott et al.   NATURE

Cellular Resolution Maps of X Chromosome Inactivation: Implications for Neural Development, Function, and Disease

(2014) Hao Wu et al.   NEURON

Chromosome X-Wide Association Study Identifies Loci for Fasting Insulin and Height and Evidence for Incomplete Dosage Compensation

(2014) Taru Tukiainen et al.   PLoS Genetics

MLL2 and KDM6A mutations in patients with Kabuki syndrome

(2013) Noriko Miyake et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART A

Xist RNA Is a Potent Suppressor of Hematologic Cancer in Mice

(2013) Eda Yildirim et al.   CELL

High-resolution Xist binding maps reveal two-step spreading during X-chromosome inactivation

(2013) Matthew D. Simon et al.   NATURE

The Xist lncRNA Exploits Three-Dimensional Genome Architecture to Spread Across the X Chromosome

(2013) J. M. Engreitz et al.   SCIENCE

Analysis of expressed SNPs identifies variable extents of expression from the human inactive X chromosome

(2013) Allison M Cotton et al.   GENOME BIOLOGY

Site-Specific Silencing of Regulatory Elements as a Mechanism of X Inactivation

(2012) J. Mauro Calabrese et al.   CELL

Molecular Signatures of Human Induced Pluripotent Stem Cells Highlight Sex Differences and Cancer Genes

(2012) Montserrat C. Anguera et al.   Cell Stem Cell

Erosion of Dosage Compensation Impacts Human iPSC Disease Modeling

(2012) Shila Mekhoubad et al.   Cell Stem Cell

Enigmatic sex disparities in cancer incidence

(2012) Gustaf Edgren et al.   EUROPEAN JOURNAL OF EPIDEMIOLOGY

Inactivation of X-linked tumor suppressor genes in human cancer

(2012) Runhua Liu et al.   Future Oncology

Cancer cells preferentially lose small chromosomes

(2012) Pascal H.G. Duijf et al.   INTERNATIONAL JOURNAL OF CANCER

RNF12 initiates X-chromosome inactivation by targeting REX1 for degradation

(2012) Cristina Gontan et al.   NATURE

Spatial partitioning of the regulatory landscape of the X-inactivation centre

(2012) Elphège P. Nora et al.   NATURE

Long non-coding RNAs and cancer: a new frontier of translational research?

(2012) R Spizzo et al.   ONCOGENE

Sex Disparities in Cancer Mortality and Survival

(2011) M. B. Cook et al.   CANCER EPIDEMIOLOGY BIOMARKERS & PREVENTION

Genes that escape from X inactivation

(2011) Joel B. Berletch et al.   HUMAN GENETICS

Recent advances in X-chromosome inactivation

(2011) Sundeep Kalantry   JOURNAL OF CELLULAR PHYSIOLOGY

Frequent pathway mutations of splicing machinery in myelodysplasia

(2011) Kenichi Yoshida et al.   NATURE

Gene silencing in X-chromosome inactivation: advances in understanding facultative heterochromatin formation

(2011) Anton Wutz   NATURE REVIEWS GENETICS

Expression and Function of a Large Non-coding RNA Gene XIST in Human Cancer

(2011) Sarah M. Weakley et al.   WORLD JOURNAL OF SURGERY

RNF12 Activates Xist and Is Essential for X Chromosome Inactivation

(2011) Tahsin Stefan Barakat et al.   PLoS Genetics

Genome–nuclear lamina interactions and gene regulation

(2010) Jop Kind et al.   CURRENT OPINION IN CELL BIOLOGY

Global survey of escape from X inactivation by RNA-sequencing in mouse

(2010) F. Yang et al.   GENOME RESEARCH

PHF6 mutations in T-cell acute lymphoblastic leukemia

(2010) Pieter Van Vlierberghe et al.   NATURE GENETICS

Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenome

(2009) J. T. Lee   GENES & DEVELOPMENT

Misbehaviour of XIST RNA in Breast Cancer Cells

(2009) Silvia M. Sirchia et al.   PLoS One

Large-Scale Population Study of Human Cell Lines Indicates that Dosage Compensation Is Virtually Complete

(2008) Colette M. Johnston et al.   PLoS Genetics

X-chromosome inactivation and epigenetic fluidity in human embryonic stem cells

(2008) S. S. Silva et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

X-inactivation in female human embryonic stem cells is in a nonrandom pattern and prone to epigenetic alterations

(2008) Y. Shen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Polycomb Proteins Targeted by a Short Repeat RNA to the Mouse X Chromosome

(2008) J. Zhao et al.   SCIENCE