Molecular landmarks of tumor hypoxia across cancer types

The Evolutionary Landscape of Localized Prostate Cancers Drives Clinical Aggression

(2018) Shadrielle Melijah G. Espiritu et al.   CELL

Intermediate Endpoints After Postprostatectomy Radiotherapy: 5-Year Distant Metastasis to Predict Overall Survival

(2018) William C. Jackson et al.   EUROPEAN UROLOGY

Sex Differences in Cancer Driver Genes and Biomarkers

(2018) Constance H. Li et al.   CANCER RESEARCH

Translating a Prognostic DNA Genomic Classifier into the Clinic: Retrospective Validation in 563 Localized Prostate Tumors

(2017) Emilie Lalonde et al.   EUROPEAN UROLOGY

Intraductal Carcinoma of the Prostate: Anonymous to Ominous

(2017) Melvin L.K. Chua et al.   EUROPEAN UROLOGY

Genomic hallmarks of localized, non-indolent prostate cancer

(2017) Michael Fraser et al.   NATURE

Neurostimulation Therapy for Pediatric Primary Enuresis: A Meta-analysis

(2017) Michael E. Chua et al.   UROLOGY

Mitochondrial mutations drive prostate cancer aggression

(2017) Julia F. Hopkins et al.   Nature Communications

BAMQL: a query language for extracting reads from BAM files

(2016) Andre P. Masella et al.   BMC BIOINFORMATICS

Comprehensive Characterization of Molecular Differences in Cancer between Male and Female Patients

(2016) Yuan Yuan et al.   CANCER CELL

Integrated Proteogenomic Characterization of Human High-Grade Serous Ovarian Cancer

(2016) Hui Zhang et al.   CELL

Proteogenomics connects somatic mutations to signalling in breast cancer

(2016) Philipp Mertins et al.   NATURE

Hypoxic control of metastasis

(2016) E. B. Rankin et al.   SCIENCE

The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes

(2016) Bernard Pereira et al.   Nature Communications

Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia

(2015) Muhammad Zaeem Noman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-CELL PHYSIOLOGY

The Clinical Significance of Hypoxia in Human Cancers

(2015) Neesha Dhani et al.   SEMINARS IN NUCLEAR MEDICINE

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

(2015) Matthew K.H. Hong et al.   Nature Communications

Age-related somatic mutations in the cancer genome

(2015) Brandon Milholland et al.   Oncotarget

PhyloWGS: Reconstructing subclonal composition and evolution from whole-genome sequencing of tumors

(2015) Amit G Deshwar et al.   GENOME BIOLOGY

ShatterProof: operational detection and quantification of chromothripsis

(2014) Shaylan K Govind et al.   BMC BIOINFORMATICS

The tumour hypoxia marker pimonidazole reflects a transcriptional programme associated with aggressive prostate cancer

(2014) H B Ragnum et al.   BRITISH JOURNAL OF CANCER

TITAN: inference of copy number architectures in clonal cell populations from tumor whole-genome sequence data

(2014) Gavin Ha et al.   GENOME RESEARCH

Tumour genomic and microenvironmental heterogeneity for integrated prediction of 5-year biochemical recurrence of prostate cancer: a retrospective cohort study

(2014) Emilie Lalonde et al.   LANCET ONCOLOGY

A tumor DNA complex aberration index is an independent predictor of survival in breast and ovarian cancer

(2014) Hans Kristian Moen Vollan et al.   Molecular Oncology

Proteogenomic characterization of human colon and rectal cancer

(2014) Bing Zhang et al.   NATURE

Discovery and saturation analysis of cancer genes across 21 tumour types

(2014) Michael S. Lawrence et al.   NATURE

Estimating telomere length from whole genome sequence data

(2014) Zhihao Ding et al.   NUCLEIC ACIDS RESEARCH

Copy number alteration burden predicts prostate cancer relapse

(2014) H. Hieronymus et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

A 26-Gene Hypoxia Signature Predicts Benefit from Hypoxia-Modifying Therapy in Laryngeal Cancer but Not Bladder Cancer

(2013) A. Eustace et al.   CLINICAL CANCER RESEARCH

Reprogramming Metabolism with Metformin Improves Tumor Oxygenation and Radiotherapy Response

(2013) V. E. Zannella et al.   CLINICAL CANCER RESEARCH

Role of hypoxia-inducible factors in breast cancer metastasis

(2013) Daniele M Gilkes et al.   Future Oncology

Pan-cancer patterns of somatic copy number alteration

(2013) Travis I Zack et al.   NATURE GENETICS

DELLY: structural variant discovery by integrated paired-end and split-read analysis

(2012) T. Rausch et al.   BIOINFORMATICS

Tumor Hypoxia Predicts Biochemical Failure following Radiotherapy for Clinically Localized Prostate Cancer

(2012) M. Milosevic et al.   CLINICAL CANCER RESEARCH

Effects of hypoxia and HIFs on cancer metabolism

(2012) Vera Mucaj et al.   INTERNATIONAL JOURNAL OF HEMATOLOGY

Accelerated Radiotherapy With Carbogen and Nicotinamide for Laryngeal Cancer: Results of a Phase III Randomized Trial

(2012) Geert O. Janssens et al.   JOURNAL OF CLINICAL ONCOLOGY

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups

(2012) Christina Curtis et al.   NATURE

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The tumor microenvironment

(2011) Cynthia E. Weber et al.   SURGICAL ONCOLOGY-OXFORD

A scalable, fully automated process for construction of sequence-ready human exome targeted capture libraries

(2011) Sheila Fisher et al.   GENOME BIOLOGY

Identifying pH independent hypoxia induced genes in human squamous cell carcinomasin vitro

(2010) Brita Singers Sørensen et al.   ACTA ONCOLOGICA

ConsensusClusterPlus: a class discovery tool with confidence assessments and item tracking

(2010) Matthew D. Wilkerson et al.   BIOINFORMATICS

Large meta-analysis of multiple cancers reveals a common, compact and highly prognostic hypoxia metagene

(2010) F M Buffa et al.   BRITISH JOURNAL OF CANCER

Integrative Genomic Profiling of Human Prostate Cancer

(2010) Barry S. Taylor et al.   CANCER CELL

Oxygen in Stem Cell Biology: A Critical Component of the Stem Cell Niche

(2010) Ahmed Mohyeldin et al.   Cell Stem Cell

The Genome Analysis Toolkit: A MapReduce framework for analyzing next-generation DNA sequencing data

(2010) A. McKenna et al.   GENOME RESEARCH

Radiotherapy With Concurrent Carbogen and Nicotinamide in Bladder Carcinoma

(2010) Peter J. Hoskin et al.   JOURNAL OF CLINICAL ONCOLOGY

ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data

(2010) K. Wang et al.   NUCLEIC ACIDS RESEARCH

The Sequence Alignment/Map format and SAMtools

(2009) H. Li et al.   BIOINFORMATICS

Fast and accurate short read alignment with Burrows-Wheeler transform

(2009) H. Li et al.   BIOINFORMATICS

A compact VEGF signature associated with distant metastases and poor outcomes

(2009) Zhiyuan Hu et al.   BMC Medicine

The key hypoxia regulated gene CAIX is upregulated in basal-like breast tumours and is associated with resistance to chemotherapy

(2009) E Y Tan et al.   BRITISH JOURNAL OF CANCER

The hematopoietic stem cell niche: Low in oxygen but a nice place to be

(2009) Pernilla Eliasson et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Hypoxia-Inducible mir-210 Regulates Normoxic Gene Expression Involved in Tumor Initiation

(2009) Xin Huang et al.   MOLECULAR CELL

An integrative genomics approach identifies Hypoxia Inducible Factor-1 (HIF-1)-target genes that form the core response to hypoxia

(2009) Yair Benita et al.   NUCLEIC ACIDS RESEARCH