Metabolism via Arginase or Nitric Oxide Synthase: Two Competing Arginine Pathways in Macrophages

Metabolic Regulation of Immune Responses

(2014) Kirthana Ganeshan et al.   Annual Review of Immunology

Gliadin activates arginase pathway in RAW264.7 cells and in human monocytes

(2014) Amelia Barilli et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

(2014) Peter J. Murray et al.   IMMUNITY

Tumor-Associated Macrophages: From Mechanisms to Therapy

(2014) Roy Noy et al.   IMMUNITY

Myeloid-Specific Disruption of Tyrosine Phosphatase Shp2 Promotes Alternative Activation of Macrophages and Predisposes Mice to Pulmonary Fibrosis

(2014) Bo Tao et al.   JOURNAL OF IMMUNOLOGY

Macrophage PTEN Regulates Expression and Secretion of Arginase I Modulating Innate and Adaptive Immune Responses

(2014) Emine Sahin et al.   JOURNAL OF IMMUNOLOGY

M1 and M2 Macrophages: The Chicken and the Egg of Immunity

(2014) Charles D. Mills et al.   Journal of Innate Immunity

Granulocyte functions are independent of arginine availability

(2014) Katharina Kapp et al.   JOURNAL OF LEUKOCYTE BIOLOGY

The IL-13/IL-4Rαaxis is involved in tuberculosis-associated pathology

(2014) Lisa Heitmann et al.   JOURNAL OF PATHOLOGY

Metabolism of stromal and immune cells in health and disease

(2014) Bart Ghesquière et al.   NATURE

Functional polarization of tumour-associated macrophages by tumour-derived lactic acid

(2014) Oscar R. Colegio et al.   NATURE

Macrophage arginase-1 controls bacterial growth and pathology in hypoxic tuberculosis granulomas

(2014) M. A. Duque-Correa et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Growth Factor and Th2 Cytokine Signaling Pathways Converge at STAT6 to Promote Arginase Expression in Progressive Experimental Visceral Leishmaniasis

(2014) E. Yaneth Osorio et al.   PLoS Pathogens

M1 and M2 Macrophages: Oracles of Health and Disease

(2013) Charles Mills   CRITICAL REVIEWS IN IMMUNOLOGY

Retinoic acid promotes the development of Arg1-expressing dendritic cells for the regulation of T-cell differentiation

(2013) Jinsam Chang et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Shaping the Murine Macrophage Phenotype: IL-4 and Cyclic AMP Synergistically Activate the Arginase I Promoter

(2013) K. E. Sheldon et al.   JOURNAL OF IMMUNOLOGY

Microenvironments in Tuberculous Granulomas Are Delineated by Distinct Populations of Macrophage Subsets and Expression of Nitric Oxide Synthase and Arginase Isoforms

(2013) J. T. Mattila et al.   JOURNAL OF IMMUNOLOGY

Arginine Transport Is Impaired in C57Bl/6 Mouse Macrophages as a Result of a Deletion in the Promoter of Slc7a2 (CAT2), and Susceptibility to Leishmania Infection Is Reduced

(2013) M. Gloria Sans-Fons et al.   JOURNAL OF INFECTIOUS DISEASES

The SLC3 and SLC7 families of amino acid transporters

(2013) Dimitrios Fotiadis et al.   MOLECULAR ASPECTS OF MEDICINE

Cytotoxicity of Tumor Antigen Specific Human T Cells Is Unimpaired by Arginine Depletion

(2013) Markus Munder et al.   PLoS One

Arginase Activity in the Blood of Patients with Visceral Leishmaniasis and HIV Infection

(2013) Yegnasew Takele et al.   PLoS Neglected Tropical Diseases

Arginase Activity - A Marker of Disease Status in Patients with Visceral Leishmaniasis in Ethiopia

(2013) Tamrat Abebe et al.   PLoS Neglected Tropical Diseases

Sustained Generation of Nitric Oxide and Control of Mycobacterial Infection Requires Argininosuccinate Synthase 1

(2012) Joseph E. Qualls et al.   Cell Host & Microbe

Orchestration of Metabolism by Macrophages

(2012) Subhra K. Biswas et al.   Cell Metabolism

Deacetylation of C/EBPβ is required for IL-4-inducedarginase-1expression in murine macrophages

(2012) Neus Serrat et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Metabolism of L-Arginine by Myeloid-Derived Suppressor Cells in Cancer: Mechanisms of T cell suppression and Therapeutic Perspectives

(2012) Patrick Raber et al.   IMMUNOLOGICAL INVESTIGATIONS

Arginine deficiency leads to impaired cofilin dephosphorylation in activated human T lymphocytes

(2012) Nadja Feldmeyer et al.   INTERNATIONAL IMMUNOLOGY

Macrophage plasticity and polarization: in vivo veritas

(2012) Antonio Sica et al.   JOURNAL OF CLINICAL INVESTIGATION

The Key Role of IL-6-Arginase Cascade for Inducing Dendritic Cell-Dependent CD4+ T Cell Dysfunction in Tumor-Bearing Mice

(2012) Y. Narita et al.   JOURNAL OF IMMUNOLOGY

Metabolic Characterization of Leishmania major Infection in Activated and Nonactivated Macrophages.

(2012) Sabrina D. Lamour et al.   JOURNAL OF PROTEOME RESEARCH

Increased arginase activity contributes to airway remodelling in chronic allergic asthma

(2011) H. Maarsingh et al.   EUROPEAN RESPIRATORY JOURNAL

Immune Evasion by Helicobacter pylori Is Mediated by Induction of Macrophage Arginase II

(2011) N. D. Lewis et al.   JOURNAL OF IMMUNOLOGY

Obstacles and opportunities for understanding macrophage polarization

(2011) P. J. Murray et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Alternative Activation of Macrophages: Mechanism and Functions

(2010) Siamon Gordon et al.   IMMUNITY

Arginase I Suppresses IL-12/IL-23p40-Driven Intestinal Inflammation during Acute Schistosomiasis

(2010) D. R. Herbert et al.   JOURNAL OF IMMUNOLOGY

L-Arginine Deprivation Regulates Cyclin D3 mRNA Stability in Human T Cells by Controlling HuR Expression

(2010) P. C. Rodriguez et al.   JOURNAL OF IMMUNOLOGY

Increased Level of Arginase Activity Correlates with Disease Severity in HIV‐Seropositive Patients

(2010) T. E. Cloke et al.   JOURNAL OF INFECTIOUS DISEASES

Control of RSV-induced lung injury by alternatively activated macrophages is IL-4Rα-, TLR4- and IFN-β-dependent

(2010) K A Shirey et al.   Mucosal Immunology

TPL-2-Mediated Activation of MAPK Downstream of TLR4 Signaling Is Coupled to Arginine Availability

(2010) V. Mieulet et al.   Science Signaling

Arginine Usage in Mycobacteria-Infected Macrophages Depends on Autocrine-Paracrine Cytokine Signaling

(2010) J. E. Qualls et al.   Science Signaling

Amino acid transporters:éminences grisesof nutrient signalling mechanisms?: Figure 1

(2009) Peter M. Taylor   BIOCHEMICAL SOCIETY TRANSACTIONS

Arginase: an emerging key player in the mammalian immune system

(2009) Markus Munder   BRITISH JOURNAL OF PHARMACOLOGY

L-Arginine deprivation impairs Leishmania major-specific T-cell responses

(2009) Markus Munder et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IL-8 induces exocytosis of arginase 1 by neutrophil polymorphonuclears in nonsmall cell lung cancer

(2009) Rita Rotondo et al.   INTERNATIONAL JOURNAL OF CANCER

Mammalian polyamine metabolism and function

(2009) Anthony E. Pegg   IUBMB LIFE

Polymorphonuclear neutrophils and T lymphocytes: strange bedfellows or brothers in arms?

(2009) Ingrid Müller et al.   TRENDS IN IMMUNOLOGY

Local Suppression of T Cell Responses by Arginase-Induced L-Arginine Depletion in Nonhealing Leishmaniasis

(2009) Manuel Modolell et al.   PLoS Neglected Tropical Diseases

Arginase-1–Expressing Macrophages Suppress Th2 Cytokine–Driven Inflammation and Fibrosis

(2009) John T. Pesce et al.   PLoS Pathogens

Toll-like receptor–induced arginase 1 in macrophages thwarts effective immunity against intracellular pathogens

(2008) Karim C El Kasmi et al.   NATURE IMMUNOLOGY

Functional role and species-specific contribution of arginases in pulmonary fibrosis

(2007) Kamila Kitowska et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY