Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Replication Stress, DNA Damage, Inflammatory Cytokines and Innate Immune Response
Authors
Keywords
-
Journal
Genes
Volume 11, Issue 4, Pages 409
Publisher
MDPI AG
Online
2020-04-10
DOI
10.3390/genes11040409
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- BRCA2 deficiency instigates cGAS-mediated inflammatory signaling and confers sensitivity to tumor necrosis factor-alpha-mediated cytotoxicity
- (2019) Anne Margriet Heijink et al. Nature Communications
- Targeting DNA Damage Response Promotes Antitumor Immunity through STING-Mediated T-cell Activation in Small Cell Lung Cancer
- (2019) Triparna Sen et al. Cancer Discovery
- cGAS in action: Expanding roles in immunity and inflammation
- (2019) Andrea Ablasser et al. SCIENCE
- Structural basis of STING binding with and phosphorylation by TBK1
- (2019) Conggang Zhang et al. NATURE
- Cryo-EM structures of STING reveal its mechanism of activation by cyclic GMP–AMP
- (2019) Guijun Shang et al. NATURE
- ATR Inhibition Potentiates the Radiation-induced Inflammatory Tumor Microenvironment
- (2019) Magnus T. Dillon et al. CLINICAL CANCER RESEARCH
- Exploiting DNA Replication Stress for Cancer Treatment
- (2019) Tajinder Ubhi et al. CANCER RESEARCH
- Bloom syndrome protein restrains innate immune sensing of micronuclei by cGAS
- (2019) Matthieu Gratia et al. JOURNAL OF EXPERIMENTAL MEDICINE
- DNA sensing by the cGAS–STING pathway in health and disease
- (2019) Mona Motwani et al. NATURE REVIEWS GENETICS
- BRCA2 abrogation triggers innate immune responses potentiated by treatment with PARP inhibitors
- (2019) Timo Reisländer et al. Nature Communications
- DNA Damage and Associated DNA Repair Defects in Disease and Premature Aging
- (2019) Vinod Tiwari et al. AMERICAN JOURNAL OF HUMAN GENETICS
- Premature mitotic entry induced by ATR inhibition potentiates olaparib inhibition‐mediated genomic instability, inflammatory signaling and cytotoxicity in BRCA2‐deficient cancer cells
- (2019) Pepijn M. Schoonen et al. Molecular Oncology
- DNA damage responses in ageing
- (2019) Paulo F. L. da Silva et al. Open Biology
- The cGAS Paradox: Contrasting Roles for cGAS-STING Pathway in Chromosomal Instability
- (2019) Christy Hong et al. Cells
- The Cytosolic DNA-Sensing cGAS–STING Pathway in Cancer
- (2019) John Kwon et al. Cancer Discovery
- Repair of DNA double-strand breaks by mammalian alternative end-joining pathways
- (2018) Annahita Sallmyr et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The cGAS–cGAMP–STING pathway connects DNA damage to inflammation, senescence, and cancer
- (2018) Tuo Li et al. JOURNAL OF EXPERIMENTAL MEDICINE
- PARP1 and PARP2 stabilise replication forks at base excision repair intermediates through Fbh1-dependent Rad51 regulation
- (2018) George E. Ronson et al. Nature Communications
- 20 Years of Mre11 Biology: No End in Sight
- (2018) Tanya T. Paull MOLECULAR CELL
- Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage
- (2018) Gillian Dunphy et al. MOLECULAR CELL
- SAMHD1 acts at stalled replication forks to prevent interferon induction
- (2018) Flavie Coquel et al. NATURE
- The therapeutic significance of mutational signatures from DNA repair deficiency in cancer
- (2018) Jennifer Ma et al. Nature Communications
- Mitochondria, Oxidative Stress and Innate Immunity
- (2018) Yuxin Chen et al. Frontiers in Physiology
- PARP inhibition enhances tumor cell–intrinsic immunity in ERCC1-deficient non–small cell lung cancer
- (2018) Roman M. Chabanon et al. JOURNAL OF CLINICAL INVESTIGATION
- SAMHD1 and the innate immune response to cytosolic DNA during DNA replication
- (2018) Flavie Coquel et al. CURRENT OPINION IN IMMUNOLOGY
- Genomic rearrangements induced by unscheduled DNA double strand breaks in somatic mammalian cells
- (2017) Ayeong So et al. FEBS Journal
- A prosurvival DNA damage-induced cytoplasmic interferon response is mediated by end resection factors and is limited by Trex1
- (2017) Erkin Erdal et al. GENES & DEVELOPMENT
- Absence of RNase H2 triggers generation of immunogenic micronuclei removed by autophagy
- (2017) Kareen Bartsch et al. HUMAN MOLECULAR GENETICS
- DNA damage-induced immune response: Micronuclei provide key platform
- (2017) Nelson O. Gekara JOURNAL OF CELL BIOLOGY
- Sensing of dangerous DNA
- (2017) Stephan Gasser et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Single-Molecule Imaging Reveals How Mre11-Rad50-Nbs1 Initiates DNA Break Repair
- (2017) Logan R. Myler et al. MOLECULAR CELL
- ATM, ATR, and DNA-PK: The Trinity at the Heart of the DNA Damage Response
- (2017) Andrew N. Blackford et al. MOLECULAR CELL
- Inactivation of DNA repair triggers neoantigen generation and impairs tumour growth
- (2017) Giovanni Germano et al. NATURE
- cGAS surveillance of micronuclei links genome instability to innate immunity
- (2017) Karen J. Mackenzie et al. NATURE
- Mitotic progression following DNA damage enables pattern recognition within micronuclei
- (2017) Shane M. Harding et al. NATURE
- The essential kinase ATR: ensuring faithful duplication of a challenging genome
- (2017) Joshua C. Saldivar et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- The multifaceted roles of PARP1 in DNA repair and chromatin remodelling
- (2017) Arnab Ray Chaudhuri et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- RAD51 interconnects between DNA replication, DNA repair and immunity
- (2017) Souparno Bhattacharya et al. NUCLEIC ACIDS RESEARCH
- Redox-sensitive alteration of replisome architecture safeguards genome integrity
- (2017) Kumar Somyajit et al. SCIENCE
- Use of CRISPR-modified human stem cell organoids to study the origin of mutational signatures in cancer
- (2017) Jarno Drost et al. SCIENCE
- Expanding functions of ADP-ribosylation in the maintenance of genome integrity
- (2017) K. Martin-Hernandez et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Topoisomerase II Inhibitors Induce DNA Damage-Dependent Interferon Responses Circumventing Ebola Virus Immune Evasion
- (2017) Priya Luthra et al. mBio
- SAMHD1 Promotes DNA End Resection to Facilitate DNA Repair by Homologous Recombination
- (2017) Waaqo Daddacha et al. Cell Reports
- R Loops in the Regulation of Antibody Gene Diversification
- (2017) Rushad Pavri Genes
- Fanconi Anemia Proteins Function in Mitophagy and Immunity
- (2016) Rhea Sumpter et al. CELL
- The DNA Structure-Specific Endonuclease MUS81 Mediates DNA Sensor STING-Dependent Host Rejection of Prostate Cancer Cells
- (2016) Samantha S.W. Ho et al. IMMUNITY
- Recognition of Endogenous Nucleic Acids by the Innate Immune System
- (2016) Axel Roers et al. IMMUNITY
- The role of neoantigens in response to immune checkpoint blockade
- (2016) Nadeem Riaz et al. INTERNATIONAL IMMUNOLOGY
- RNase H2 catalytic core Aicardi-Goutières syndrome–related mutant invokes cGAS–STING innate immune-sensing pathway in mice
- (2016) Vladislav Pokatayev et al. JOURNAL OF EXPERIMENTAL MEDICINE
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- PARP1 Links CHD2-Mediated Chromatin Expansion and H3.3 Deposition to DNA Repair by Non-homologous End-Joining
- (2016) Martijn S. Luijsterburg et al. MOLECULAR CELL
- The nature of mutations induced by replication–transcription collisions
- (2016) T. Sabari Sankar et al. NATURE
- NADPH oxidases: new actors in thyroid cancer?
- (2016) Rabii Ameziane-El-Hassani et al. Nature Reviews Endocrinology
- Transcription–replication conflicts: how they occur and how they are resolved
- (2016) Tatiana García-Muse et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Replication stress: getting back on track
- (2016) Matteo Berti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- ROS and ROS-Mediated Cellular Signaling
- (2016) Jixiang Zhang et al. Oxidative Medicine and Cellular Longevity
- RPA and Rad51 constitute a cell intrinsic mechanism to protect the cytosol from self DNA
- (2016) Christine Wolf et al. Nature Communications
- Replication stress: getting back on track
- (2016) Matteo Berti et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Epidermal Nbn deletion causes premature hair loss and a phenotype resembling psoriasiform dermatitis
- (2016) Philipp Seidel et al. Oncotarget
- Intracellular STING inactivation sensitizes breast cancer cells to genotoxic agents
- (2016) Julie Gaston et al. Oncotarget
- Association and prognostic significance of BRCA1/2-mutation status with neoantigen load, number of tumor-infiltrating lymphocytes and expression of PD-1/PD-L1 in high grade serous ovarian cancer
- (2016) Kyle C. Strickland et al. Oncotarget
- Deregulation of STING Signaling in Colorectal Carcinoma Constrains DNA Damage Responses and Correlates With Tumorigenesis
- (2016) Tianli Xia et al. Cell Reports
- Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress
- (2016) Therese Wilhelm et al. PLoS Genetics
- Activation of STING-Dependent Innate Immune Signaling By S-Phase-Specific DNA Damage in Breast Cancer
- (2016) Eileen E. Parkes et al. JNCI-Journal of the National Cancer Institute
- DNA Damage Response and Immune Defense: Links and Mechanisms
- (2016) Rania Nakad et al. Frontiers in Genetics
- Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production
- (2016) Christelle Brégnard et al. EBioMedicine
- DNA Replication Stress as a Hallmark of Cancer
- (2015) Morgane Macheret et al. Annual Review of Pathology-Mechanisms of Disease
- NBS1 is required for macrophage homeostasis and functional activity in mice
- (2015) S. Pereira-Lopes et al. BLOOD
- DNA Damage Primes the Type I Interferon System via the Cytosolic DNA Sensor STING to Promote Anti-Microbial Innate Immunity
- (2015) Anetta Härtlova et al. IMMUNITY
- Human Disease Phenotypes Associated With Mutations in TREX1
- (2015) Gillian I. Rice et al. JOURNAL OF CLINICAL IMMUNOLOGY
- Cutting Edge: cGAS Is Required for Lethal Autoimmune Disease in the Trex1-Deficient Mouse Model of Aicardi–Goutières Syndrome
- (2015) Elizabeth E. Gray et al. JOURNAL OF IMMUNOLOGY
- The Extracellular IFI16 Protein Propagates Inflammation in Endothelial Cells Via p38 MAPK and NF-κB p65 Activation
- (2015) Mandar Bawadekar et al. JOURNAL OF INTERFERON AND CYTOKINE RESEARCH
- R loops: new modulators of genome dynamics and function
- (2015) José M. Santos-Pereira et al. NATURE REVIEWS GENETICS
- Activation of cyclic GMP-AMP synthase by self-DNA causes autoimmune diseases
- (2015) Daxing Gao et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Genome-Derived Cytosolic DNA Mediates Type I Interferon-Dependent Rejection of B Cell Lymphoma Cells
- (2015) Yu J. Shen et al. Cell Reports
- DNA-Damage-Induced Type I Interferon Promotes Senescence and Inhibits Stem Cell Function
- (2015) Qiujing Yu et al. Cell Reports
- DNA Repair Cofactors ATMIN and NBS1 Are Required to Suppress T Cell Activation
- (2015) Jana Prochazkova et al. PLoS Genetics
- BRCA1 Regulates IFI16 Mediated Nuclear Innate Sensing of Herpes Viral DNA and Subsequent Induction of the Innate Inflammasome and Interferon-β Responses
- (2015) Dipanjan Dutta et al. PLoS Pathogens
- Replication Stress in Mammalian Cells and Its Consequences for Mitosis
- (2015) Camille Gelot et al. Genes
- RAE1 Ligands for the NKG2D Receptor Are Regulated by STING-Dependent DNA Sensor Pathways in Lymphoma
- (2014) Adeline R. Lam et al. CANCER RESEARCH
- Self-DNA, STING-dependent signaling and the origins of autoinflammatory disease
- (2014) Jeonghyun Ahn et al. CURRENT OPINION IN IMMUNOLOGY
- The clinical impact of deficiency in DNA non-homologous end-joining
- (2014) Lisa Woodbine et al. DNA REPAIR
- The Mre11/Rad50/Nbs1 complex: Recent insights into catalytic activities and ATP-driven conformational changes
- (2014) Tanya T. Paull et al. EXPERIMENTAL CELL RESEARCH
- STING-Dependent Cytosolic DNA Sensing Promotes Radiation-Induced Type I Interferon-Dependent Antitumor Immunity in Immunogenic Tumors
- (2014) Liufu Deng et al. IMMUNITY
- Apurinic/Apyrimidinic Endonuclease 2 Regulates the Expansion of Germinal Centers by Protecting against Activation-Induced Cytidine Deaminase–Independent DNA Damage in B Cells
- (2014) Jeroen E. J. Guikema et al. JOURNAL OF IMMUNOLOGY
- Cutting Edge: STING Mediates Protection against Colorectal Tumorigenesis by Governing the Magnitude of Intestinal Inflammation
- (2014) Qifan Zhu et al. JOURNAL OF IMMUNOLOGY
- IgH Chain Class Switch Recombination: Mechanism and Regulation
- (2014) Janet Stavnezer et al. JOURNAL OF IMMUNOLOGY
- Cytosolic-DNA-Mediated, STING-Dependent Proinflammatory Gene Induction Necessitates Canonical NF- B Activation through TBK1
- (2014) T. Abe et al. JOURNAL OF VIROLOGY
- Transcription-Coupled Nucleotide Excision Repair Factors Promote R-Loop-Induced Genome Instability
- (2014) Julie Sollier et al. MOLECULAR CELL
- Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production
- (2014) Susanne Roth et al. NATURE IMMUNOLOGY
- Cancer cell–autonomous contribution of type I interferon signaling to the efficacy of chemotherapy
- (2014) Antonella Sistigu et al. NATURE MEDICINE
- The causes of replication stress and their consequences on genome stability and cell fate
- (2014) Indiana Magdalou et al. SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY
- Inflammation-driven carcinogenesis is mediated through STING
- (2014) Jeonghyun Ahn et al. Nature Communications
- PARP1-Driven Poly-ADP-Ribosylation Regulates BRCA1 Function in Homologous Recombination-Mediated DNA Repair
- (2014) Y. Hu et al. Cancer Discovery
- Altered mucosal immune response after acute lung injury in a murine model of Ataxia Telangiectasia
- (2014) Olaf Eickmeier et al. BMC Pulmonary Medicine
- The Cytosolic DNA Sensor cGAS Forms an Oligomeric Complex with DNA and Undergoes Switch-like Conformational Changes in the Activation Loop
- (2014) Xu Zhang et al. Cell Reports
- Is Non-Homologous End-Joining Really an Inherently Error-Prone Process?
- (2014) Mireille Bétermier et al. PLoS Genetics
- Is homologous recombination really an error-free process?
- (2014) Josée Guirouilh-Barbat et al. Frontiers in Genetics
- Reactive Oxygen Species in Inflammation and Tissue Injury
- (2013) Manish Mittal et al. ANTIOXIDANTS & REDOX SIGNALING
- NADPH Oxidases: A Perspective on Reactive Oxygen Species Production in Tumor Biology
- (2013) Jennifer L. Meitzler et al. ANTIOXIDANTS & REDOX SIGNALING
- Cyclic [G(2′,5′)pA(3′,5′)p] Is the Metazoan Second Messenger Produced by DNA-Activated Cyclic GMP-AMP Synthase
- (2013) Pu Gao et al. CELL
- DNA Damage Triggers a Chronic Autoinflammatory Response, Leading to Fat Depletion in NER Progeria
- (2013) Ismene Karakasilioti et al. Cell Metabolism
- How unfinished business from S-phase affects mitosis and beyond
- (2013) Hocine W Mankouri et al. EMBO JOURNAL
- Anthracyclines Induce DNA Damage Response-Mediated Protection against Severe Sepsis
- (2013) Nuno Figueiredo et al. IMMUNITY
- Oxidative Damage of DNA Confers Resistance to Cytosolic Nuclease TREX1 Degradation and Potentiates STING-Dependent Immune Sensing
- (2013) Nadine Gehrke et al. IMMUNITY
- Immune Sensing of DNA
- (2013) Søren R. Paludan et al. IMMUNITY
- Molecular Basis of DNA Recognition in the Immune System
- (2013) M. K. Atianand et al. JOURNAL OF IMMUNOLOGY
- cGAS produces a 2′-5′-linked cyclic dinucleotide second messenger that activates STING
- (2013) Andrea Ablasser et al. NATURE
- Structural mechanism of cytosolic DNA sensing by cGAS
- (2013) Filiz Civril et al. NATURE
- Causes and consequences of replication stress
- (2013) Michelle K. Zeman et al. NATURE CELL BIOLOGY
- Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells
- (2013) T. Wilhelm et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Role of poly(ADP-ribose) polymerase-1 in the removal of UV-induced DNA lesions by nucleotide excision repair
- (2013) M. Robu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking
- (2013) T. Kondo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- IFI16 DNA Sensor Is Required for Death of Lymphoid CD4 T Cells Abortively Infected with HIV
- (2013) K. M. Monroe et al. SCIENCE
- Postreplicative Mismatch Repair
- (2013) J. Jiricny Cold Spring Harbor Perspectives in Biology
- DNA Damage Sensing by the ATM and ATR Kinases
- (2013) A. Marechal et al. Cold Spring Harbor Perspectives in Biology
- A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining
- (2013) Anastazja Grabarz et al. Cell Reports
- The Innate Immune DNA Sensor cGAS Produces a Noncanonical Cyclic Dinucleotide that Activates Human STING
- (2013) Elie J. Diner et al. Cell Reports
- Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1
- (2012) S. Ying et al. CANCER RESEARCH
- Aging-associated inflammation in healthy Japanese individuals and patients with Werner syndrome
- (2012) Makoto Goto et al. EXPERIMENTAL GERONTOLOGY
- Autoimmunity Initiates in Nonhematopoietic Cells and Progresses via Lymphocytes in an Interferon-Dependent Autoimmune Disease
- (2012) Alevtina Gall et al. IMMUNITY
- Role of Nitrative and Oxidative DNA Damage in Inflammation-Related Carcinogenesis
- (2012) Mariko Murata et al. JOURNAL OF BIOMEDICINE AND BIOTECHNOLOGY
- PARP1 promotes nucleotide excision repair through DDB2 stabilization and recruitment of ALC1
- (2012) Alex Pines et al. JOURNAL OF CELL BIOLOGY
- NF-κB inhibition delays DNA damage–induced senescence and aging in mice
- (2012) Jeremy S. Tilstra et al. JOURNAL OF CLINICAL INVESTIGATION
- BRCA Mutation Frequency and Patterns of Treatment Response in BRCA Mutation–Positive Women With Ovarian Cancer: A Report From the Australian Ovarian Cancer Study Group
- (2012) Kathryn Alsop et al. JOURNAL OF CLINICAL ONCOLOGY
- R Loops: From Transcription Byproducts to Threats to Genome Stability
- (2012) Andrés Aguilera et al. MOLECULAR CELL
- Topoisomerase I poisoning results in PARP-mediated replication fork reversal
- (2012) Arnab Ray Chaudhuri et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Visualization of a DNA-PK/PARP1 complex
- (2012) Laura Spagnolo et al. NUCLEIC ACIDS RESEARCH
- Various modes of cell death induced by DNA damage
- (2012) O Surova et al. ONCOGENE
- Pleiotropic Cellular Functions of PARP1 in Longevity and Aging: Genome Maintenance Meets Inflammation
- (2012) Aswin Mangerich et al. Oxidative Medicine and Cellular Longevity
- Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
- (2012) L. Sun et al. SCIENCE
- Mammalian mismatch repair: error-free or error-prone?
- (2012) Javier Peña-Diaz et al. TRENDS IN BIOCHEMICAL SCIENCES
- Signaling in Innate Immunity and Inflammation
- (2012) K. Newton et al. Cold Spring Harbor Perspectives in Biology
- DNA-PK is a DNA sensor for IRF-3-dependent innate immunity
- (2012) Brian J Ferguson et al. eLife
- Defective DNA double-strand break repair in pediatric systemic lupus erythematosus
- (2011) Robert C. Davies et al. ARTHRITIS AND RHEUMATISM
- Role of peroxisomes in ROS/RNS-metabolism: Implications for human disease
- (2011) Marc Fransen et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE
- The Efficacy of Radiotherapy Relies upon Induction of Type I Interferon-Dependent Innate and Adaptive Immunity
- (2011) B. C. Burnette et al. CANCER RESEARCH
- Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11
- (2011) Katharina Schlacher et al. CELL
- Linking RNA Polymerase Backtracking to Genome Instability in E. coli
- (2011) Dipak Dutta et al. CELL
- The Werner syndrome protein affects the expression of genes involved in adipogenesis and inflammation in addition to cell cycle and DNA damage responses
- (2011) Ramachander V.N. Turaga et al. CELL CYCLE
- Aicardi-Goutieres syndrome: from patients to genes and beyond
- (2011) C Chahwan et al. CLINICAL GENETICS
- Premature aging and cancer in nucleotide excision repair-disorders
- (2011) K. Diderich et al. DNA REPAIR
- PARP-1 enhances the mismatch-dependence of 5′-directed excision in human mismatch repair in vitro
- (2011) Yiyong Liu et al. DNA REPAIR
- BLM-DNA2-RPA-MRN and EXO1-BLM-RPA-MRN constitute two DNA end resection machineries for human DNA break repair
- (2011) A. V. Nimonkar et al. GENES & DEVELOPMENT
- Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces Type III Rather Than Type I IFN
- (2011) X. Zhang et al. JOURNAL OF IMMUNOLOGY
- Activation of Interferon-Stimulated Genes by -Ray Irradiation Independently of the Ataxia Telangiectasia Mutated-p53 Pathway
- (2011) T. Sugihara et al. MOLECULAR CANCER RESEARCH
- SNPs in DNA repair genes associated to meningitis and host immune response
- (2011) Thayse Azevedo da Silva et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Reactive Oxygen Species (ROS)––Induced genetic and epigenetic alterations in human carcinogenesis
- (2011) Dominique Ziech et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Recapitulation of premature ageing with iPSCs from Hutchinson–Gilford progeria syndrome
- (2011) Guang-Hui Liu et al. NATURE
- Co-directional replication–transcription conflicts lead to replication restart
- (2011) Houra Merrikh et al. NATURE
- STING is a direct innate immune sensor of cyclic di-GMP
- (2011) Dara L. Burdette et al. NATURE
- Ascorbate improves metabolic abnormalities in Wrn mutant mice but not the free radical scavenger catechin
- (2010) Michel Lebel et al. Annals of the New York Academy of Sciences
- Making the best of the loose ends: Mre11/Rad50 complexes and Sae2 promote DNA double-strand break resection
- (2010) Tanya T. Paull DNA REPAIR
- The MRN complex in double-strand break repair and telomere maintenance
- (2010) Brandon J. Lamarche et al. FEBS LETTERS
- The DNA Damage Response: Making It Safe to Play with Knives
- (2010) Alberto Ciccia et al. MOLECULAR CELL
- Genomic instability — an evolving hallmark of cancer
- (2010) Simona Negrini et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Co-Orientation of Replication and Transcription Preserves Genome Integrity
- (2010) Anjana Srivatsan et al. PLoS Genetics
- The structural biochemistry of the superoxide dismutases
- (2009) J.J.P. Perry et al. BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS
- Aicardi-Goutieres syndrome
- (2009) S. Orcesi et al. BRITISH MEDICAL BULLETIN
- DNA Repair in Mammalian Cells
- (2009) T. Nouspikel CELLULAR AND MOLECULAR LIFE SCIENCES
- PARP is activated at stalled forks to mediate Mre11-dependent replication restart and recombination
- (2009) Helen E Bryant et al. EMBO JOURNAL
- Aicardi-Goutieres syndrome and related phenotypes: linking nucleic acid metabolism with autoimmunity
- (2009) Y. J. Crow et al. HUMAN MOLECULAR GENETICS
- A Genome-wide siRNA Screen Reveals Diverse Cellular Processes and Pathways that Mediate Genome Stability
- (2009) Renee D. Paulsen et al. MOLECULAR CELL
- The DNA-damage response in human biology and disease
- (2009) Stephen P. Jackson et al. NATURE
- STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
- (2009) Hiroki Ishikawa et al. NATURE
- Multiple functions of MRN in end-joining pathways during isotype class switching
- (2009) Maria Dinkelmann et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Role of mammalian Mre11 in classical and alternative nonhomologous end joining
- (2009) Anyong Xie et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Role of Mre11 in chromosomal nonhomologous end joining in mammalian cells
- (2009) Emilie Rass et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Structural and Functional Relationships of the XPF/MUS81 Family of Proteins
- (2008) Alberto Ciccia et al. Annual Review of Biochemistry
- Mechanism and Regulation of Class Switch Recombination
- (2008) Janet Stavnezer et al. Annual Review of Immunology
- DNA helicases Sgs1 and BLM promote DNA double-strand break resection
- (2008) S. Gravel et al. GENES & DEVELOPMENT
- A DNA-PKcs mutation in a radiosensitive T–B– SCID patient inhibits Artemis activation and nonhomologous end-joining
- (2008) Mirjam van der Burg et al. JOURNAL OF CLINICAL INVESTIGATION
- Prevalence and clinical associations of anti-Ku antibodies in systemic autoimmune diseases
- (2008) I Cavazzana et al. LUPUS
- STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
- (2008) Hiroki Ishikawa et al. NATURE
- Ataxia-telangiectasia: from a rare disorder to a paradigm for cell signalling and cancer
- (2008) Martin F. Lavin NATURE REVIEWS MOLECULAR CELL BIOLOGY
- A homologous recombination defect affects replication-fork progression in mammalian cells
- (2007) F. Daboussi et al. JOURNAL OF CELL SCIENCE
Find Funding. Review Successful Grants.
Explore over 25,000 new funding opportunities and over 6,000,000 successful grants.
ExploreFind the ideal target journal for your manuscript
Explore over 38,000 international journals covering a vast array of academic fields.
Search