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Title
DNA damage responses in ageing
Authors
Keywords
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Journal
Open Biology
Volume 9, Issue 11, Pages 190168
Publisher
The Royal Society
Online
2019-11-20
DOI
10.1098/rsob.190168
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Note: Only part of the references are listed.- Cells exhibiting strong p16INK4a promoter activation in vivo display features of senescence
- (2019) Jie-Yu Liu et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2019) Allyson K. Palmer et al. AGING CELL
- New Trend in Old-Age Mortality: Gompertzialization of Mortality Trajectory
- (2019) Leonid A. Gavrilov et al. GERONTOLOGY
- Dietary restriction delays the secretion of senescence associated secretory phenotype by reducing DNA damage response in the process of renal aging
- (2018) Wenjuan Wang et al. EXPERIMENTAL GERONTOLOGY
- Brain–gut communications via distinct neuroendocrine signals bidirectionally regulate longevity inC. elegans
- (2018) Bi Zhang et al. GENES & DEVELOPMENT
- Role of hypothalamus in aging and its underlying cellular mechanisms
- (2018) Keetae Kim et al. MECHANISMS OF AGEING AND DEVELOPMENT
- The senescent bystander effect is caused by ROS-activated NF-κB signalling
- (2018) Glyn Nelson et al. MECHANISMS OF AGEING AND DEVELOPMENT
- Senolytics improve physical function and increase lifespan in old age
- (2018) Ming Xu et al. NATURE MEDICINE
- A PQM-1-Mediated Response Triggers Transcellular Chaperone Signaling and Regulates Organismal Proteostasis
- (2018) Daniel O’Brien et al. Cell Reports
- Naked mole-rat mortality rates defy Gompertzian laws by not increasing with age
- (2018) J Graham Ruby et al. eLife
- Reactivation of RNA metabolism underlies somatic restoration after adult reproductive diapause in C. elegans
- (2018) Nikolay Burnaevskiy et al. eLife
- The bystander effect contributes to the accumulation of senescent cells in vivo
- (2018) Paulo F. L. da Silva et al. AGING CELL
- A simple answer to complex questions: Caenorhabditis elegans as an experimental model for examining the DNA damage response and disease genes
- (2017) Matthias Rieckher et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Change in the Rate of Biological Aging in Response to Caloric Restriction: CALERIE Biobank Analysis
- (2017) Daniel W Belsky et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- DNA mismatch repair and its many roles in eukaryotic cells
- (2017) Dekang Liu et al. MUTATION RESEARCH-REVIEWS IN MUTATION RESEARCH
- Hypothalamic stem cells control ageing speed partly through exosomal miRNAs
- (2017) Yalin Zhang et al. NATURE
- Non-homologous DNA end joining and alternative pathways to double-strand break repair
- (2017) Howard H. Y. Chang et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Inflammaging and ‘Garb-aging’
- (2017) Claudio Franceschi et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Caloric restriction improves health and survival of rhesus monkeys
- (2017) Julie A. Mattison et al. Nature Communications
- Cellular senescence mediates fibrotic pulmonary disease
- (2017) Marissa J. Schafer et al. Nature Communications
- Cellular senescence drives age-dependent hepatic steatosis
- (2017) Mikolaj Ogrodnik et al. Nature Communications
- Multilayered Reprogramming in Response to Persistent DNA Damage in C. elegans
- (2017) Diletta Edifizi et al. Cell Reports
- Mitochondria in Cell Senescence: Is Mitophagy the Weakest Link?
- (2017) Viktor I. Korolchuk et al. EBioMedicine
- Chronic senolytic treatment alleviates established vasomotor dysfunction in aged or atherosclerotic mice
- (2016) Carolyn M. Roos et al. AGING CELL
- Robust, universal biomarker assay to detect senescent cells in biological specimens
- (2016) Konstantinos Evangelou et al. AGING CELL
- Neuropeptide signals cell non-autonomous mitochondrial unfolded protein response
- (2016) Li-Wa Shao et al. CELL RESEARCH
- JAK/STAT signalling mediates cell survival in response to tissue stress
- (2016) Marco La Fortezza et al. DEVELOPMENT
- Interplay between Fanconi anemia and homologous recombination pathways in genome integrity
- (2016) Johanna Michl et al. EMBO JOURNAL
- Identification of Senescent Cells in the Bone Microenvironment
- (2016) Joshua N Farr et al. JOURNAL OF BONE AND MINERAL RESEARCH
- Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
- (2016) Darren J. Baker et al. NATURE
- Senescence-associated secretory phenotype contributes to pathological angiogenesis in retinopathy
- (2016) M. Oubaha et al. Science Translational Medicine
- Systemic DNA damage responses in aging and diseases
- (2016) Flavia Ribezzo et al. SEMINARS IN CANCER BIOLOGY
- Deep Proteome Analysis Identifies Age-Related Processes in C. elegans
- (2016) Vikram Narayan et al. Cell Systems
- Longevity and stress in Caenorhabditis elegans
- (2016) Katherine I. Zhou et al. Aging-US
- Specific lipofuscin staining as a novel biomarker to detect replicative and stress-induced senescence. A method applicable in cryo-preserved and archival tissues
- (2016) EA Georgakopoulou et al. Aging-US
- Inflammaging: disturbed interplay between autophagy and inflammasomes
- (2016) Antero Salminen et al. Aging-US
- The Achilles’ heel of senescent cells: from transcriptome to senolytic drugs
- (2015) Yi Zhu et al. AGING CELL
- Widespread Proteome Remodeling and Aggregation in Aging C. elegans
- (2015) Dirk M. Walther et al. CELL
- Neuronal CRTC-1 Governs Systemic Mitochondrial Metabolism and Lifespan via a Catecholamine Signal
- (2015) Kristopher Burkewitz et al. CELL
- Promoting Health and Longevity through Diet: From Model Organisms to Humans
- (2015) Luigi Fontana et al. CELL
- The impact of base excision DNA repair in age-related neurodegenerative diseases
- (2015) Giovana S. Leandro et al. MUTATION RESEARCH-FUNDAMENTAL AND MOLECULAR MECHANISMS OF MUTAGENESIS
- Cell nonautonomous activation of flavin-containing monooxygenase promotes longevity and health span
- (2015) S. F. Leiser et al. SCIENCE
- DNA polymerase β deficiency leads to neurodegeneration and exacerbates Alzheimer disease phenotypes
- (2015) Peter Sykora et al. NUCLEIC ACIDS RESEARCH
- Physiological and pathological consequences of cellular senescence
- (2014) Dominick G. A. Burton et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- An Essential Role for Senescent Cells in Optimal Wound Healing through Secretion of PDGF-AA
- (2014) Marco Demaria et al. DEVELOPMENTAL CELL
- Biodemography of Old-Age Mortality in Humans and Rodents
- (2014) N. S. Gavrilova et al. JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES
- Geriatric muscle stem cells switch reversible quiescence into senescence
- (2014) Pedro Sousa-Victor et al. NATURE
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- (2014) Michael M. Mueller et al. NATURE CELL BIOLOGY
- Systemic stress signalling: understanding the cell non-autonomous control of proteostasis
- (2014) Rebecca C. Taylor et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- Cellular senescence: from physiology to pathology
- (2014) Daniel Muñoz-Espín et al. NATURE REVIEWS MOLECULAR CELL BIOLOGY
- DNA Damage and Its Links to Neurodegeneration
- (2014) Ram Madabhushi et al. NEURON
- Cellular and molecular longevity pathways: the old and the new
- (2014) Vassiliki Nikoletopoulou et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Systemic DNA damage responses: organismal adaptations to genome instability
- (2014) Maria A. Ermolaeva et al. TRENDS IN GENETICS
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- (2014) A. Mehta et al. Cold Spring Harbor Perspectives in Biology
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- (2014) Diana Jurk et al. Nature Communications
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- (2014) Sander Barnhoorn et al. PLoS Genetics
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- (2013) Carlos López-Otín et al. CELL
- DNA damage leads to progressive replicative decline but extends the life span of long-lived mutant animals
- (2013) H Lans et al. CELL DEATH AND DIFFERENTIATION
- DNA strand break repair and neurodegeneration
- (2013) Stuart L. Rulten et al. DNA REPAIR
- The role of DNA repair in brain related disease pathology
- (2013) Chandrika Canugovi et al. DNA REPAIR
- Autophagy and leucine promote chronological longevity and respiration proficiency during calorie restriction in yeast
- (2013) John P. Aris et al. EXPERIMENTAL GERONTOLOGY
- The effects of dietary restriction on oxidative stress in rodents
- (2013) Michael E. Walsh et al. FREE RADICAL BIOLOGY AND MEDICINE
- p53-dependent release of Alarmin HMGB1 is a central mediator of senescent phenotypes
- (2013) Albert R. Davalos et al. JOURNAL OF CELL BIOLOGY
- Cockayne syndrome pathogenesis: Lessons from mouse models
- (2013) Dick Jaarsma et al. MECHANISMS OF AGEING AND DEVELOPMENT
- DNA damage in germ cells induces an innate immune response that triggers systemic stress resistance
- (2013) Maria A. Ermolaeva et al. NATURE
- Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH
- (2013) Guo Zhang et al. NATURE
- A complex secretory program orchestrated by the inflammasome controls paracrine senescence
- (2013) Juan Carlos Acosta et al. NATURE CELL BIOLOGY
- Repair of Strand Breaks by Homologous Recombination
- (2013) M. Jasin et al. Cold Spring Harbor Perspectives in Biology
- The role of DNA damage and repair in aging through the prism of Koch-like criteria
- (2012) Alexey A. Moskalev et al. AGEING RESEARCH REVIEWS
- A senescent cell bystander effect: senescence-induced senescence
- (2012) Glyn Nelson et al. AGING CELL
- Postmitotic neurons develop a p21-dependent senescence-like phenotype driven by a DNA damage response
- (2012) Diana Jurk et al. AGING CELL
- Age-associated inflammation inhibits epidermal stem cell function
- (2012) J. Doles et al. GENES & DEVELOPMENT
- NF-κB inhibition delays DNA damage–induced senescence and aging in mice
- (2012) Jeremy S. Tilstra et al. JOURNAL OF CLINICAL INVESTIGATION
- Lamin B1 loss is a senescence-associated biomarker
- (2012) Adam Freund et al. MOLECULAR BIOLOGY OF THE CELL
- Diseases Associated with Defective Responses to DNA Damage
- (2012) M. O'Driscoll Cold Spring Harbor Perspectives in Biology
- Telomeres are favoured targets of a persistent DNA damage response in ageing and stress-induced senescence
- (2012) Graeme Hewitt et al. Nature Communications
- The Cell-Non-Autonomous Nature of Electron Transport Chain-Mediated Longevity
- (2011) Jenni Durieux et al. CELL
- Dynamic Coordination of Innate Immune Signaling and Insulin Signaling Regulates Systemic Responses to Localized DNA Damage
- (2011) Jason Karpac et al. DEVELOPMENTAL CELL
- Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
- (2011) Darren J. Baker et al. NATURE
- Aging in the Natural World: Comparative Data Reveal Similar Mortality Patterns Across Primates
- (2011) A. M. Bronikowski et al. SCIENCE
- A pathway that links reproductive status to lifespan in Caenorhabditis elegans
- (2010) Cynthia Kenyon Annals of the New York Academy of Sciences
- The Senescence-Associated Secretory Phenotype: The Dark Side of Tumor Suppression
- (2010) Jean-Philippe Coppé et al. Annual Review of Pathology-Mechanisms of Disease
- Metabolic Regulation of Stem Cell Behavior and Implications for Aging
- (2010) Heinrich Jasper et al. Cell Metabolism
- With TOR, Less Is More: A Key Role for the Conserved Nutrient-Sensing TOR Pathway in Aging
- (2010) Pankaj Kapahi et al. Cell Metabolism
- Using synthetic DNA interstrand crosslinks to elucidate repair pathways and identify new therapeutic targets for cancer chemotherapy
- (2010) Angelo Guainazzi et al. CELLULAR AND MOLECULAR LIFE SCIENCES
- Cellular senescence: putting the paradoxes in perspective
- (2010) Judith Campisi CURRENT OPINION IN GENETICS & DEVELOPMENT
- The genetics of ageing
- (2010) Cynthia J. Kenyon NATURE
- Mutations in PNKP cause microcephaly, seizures and defects in DNA repair
- (2010) Jun Shen et al. NATURE GENETICS
- Expression ofp16INK4ain peripheral blood T-cells is a biomarker of human aging
- (2009) Yan Liu et al. AGING CELL
- DNA damage response and cellular senescence in tissues of aging mice
- (2009) Chunfang Wang et al. AGING CELL
- Cytokine/Jak/Stat Signaling Mediates Regeneration and Homeostasis in the Drosophila Midgut
- (2009) Huaqi Jiang et al. CELL
- Update on Slow Aging and Negligible Senescence – A Mini-Review
- (2009) Caleb E. Finch GERONTOLOGY
- Persistent transcription-blocking DNA lesions trigger somatic growth attenuation associated with longevity
- (2009) George A. Garinis et al. NATURE CELL BIOLOGY
- DNA Damage, Aging, and Cancer
- (2009) Jan H.J. Hoeijmakers NEW ENGLAND JOURNAL OF MEDICINE
- Association ofFOXO3Avariation with human longevity confirmed in German centenarians
- (2009) Friederike Flachsbart et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Starvation Protects Germline Stem Cells and Extends Reproductive Longevity in C. elegans
- (2009) G. Angelo et al. SCIENCE
- Aging and Survival: The Genetics of Life Span Extension by Dietary Restriction
- (2008) William Mair et al. Annual Review of Biochemistry
- Cellular senescence in vivo: a barrier to tumorigenesis
- (2008) Alexandre Prieur et al. CURRENT OPINION IN CELL BIOLOGY
- C. elegans dauer formation and the molecular basis of plasticity
- (2008) N. Fielenbach et al. GENES & DEVELOPMENT
- Negligible senescence in the longest living rodent, the naked mole-rat: insights from a successfully aging species
- (2008) Rochelle Buffenstein JOURNAL OF COMPARATIVE PHYSIOLOGY B-BIOCHEMICAL SYSTEMIC AND ENVIRONMENTAL PHYSIOLOGY
- An Xpb Mouse Model for Combined Xeroderma Pigmentosum and Cockayne Syndrome Reveals Progeroid Features upon Further Attenuation of DNA Repair
- (2008) J.-O. Andressoo et al. MOLECULAR AND CELLULAR BIOLOGY
- Sealing the gap between nuclear DNA damage and longevity
- (2008) Björn Schumacher et al. MOLECULAR AND CELLULAR ENDOCRINOLOGY
- Single-strand break repair and genetic disease
- (2008) Keith W. Caldecott NATURE REVIEWS GENETICS
- A Role for Autophagy in the Extension of Lifespan by Dietary Restriction in C. elegans
- (2008) Malene Hansen et al. PLoS Genetics
- FOXO3A genotype is strongly associated with human longevity
- (2008) B. J. Willcox et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Long-Term Effects of Caloric Restriction or Exercise on DNA and RNA Oxidation Levels in White Blood Cells and Urine in Humans
- (2008) Tim Hofer et al. REJUVENATION RESEARCH
- Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor
- (2008) Jean-Philippe Coppé et al. PLOS BIOLOGY
- Delayed and Accelerated Aging Share Common Longevity Assurance Mechanisms
- (2008) Björn Schumacher et al. PLoS Genetics
- Activation of innate immunity system during aging: NF-kB signaling is the molecular culprit of inflamm-aging
- (2007) Antero Salminen et al. AGEING RESEARCH REVIEWS
- Remarkable longevity and stress resistance of nematode PI3K-null mutants
- (2007) Srinivas Ayyadevara et al. AGING CELL
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