Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production

Published 2016 View Full Article

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Title
Upregulated LINE-1 Activity in the Fanconi Anemia Cancer Susceptibility Syndrome Leads to Spontaneous Pro-inflammatory Cytokine Production
Authors
Keywords
Inflammation, DNA damage, SLX4 complex, endogenous retroelement, Interferon, Fanconi Anemia, cGAS-STING, Innate immune sensing, Cytoplasmic DNA
Journal
EBioMedicine
Volume 8, Issue -, Pages 184-194
Publisher
Elsevier BV
Online
2016-05-08
DOI
10.1016/j.ebiom.2016.05.005

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