Rad50-CARD9 interactions link cytosolic DNA sensing to IL-1β production

Differential Use of CARD9 by Dectin-1 in Macrophages and Dendritic Cells

(2014) H. S. Goodridge et al.   JOURNAL OF IMMUNOLOGY

Immune Sensing of DNA

(2013) Søren R. Paludan et al.   IMMUNITY

Cytosolic Sensing of Viruses

(2013) Delphine Goubau et al.   IMMUNITY

Vaccinia virus immune evasion: mechanisms, virulence and immunogenicity

(2013) G. L. Smith et al.   JOURNAL OF GENERAL VIROLOGY

DNA damage sensor MRE11 recognizes cytosolic double-stranded DNA and induces type I interferon by regulating STING trafficking

(2013) T. Kondo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Pivotal Roles of cGAS-cGAMP Signaling in Antiviral Defense and Immune Adjuvant Effects

(2013) X.-D. Li et al.   SCIENCE

Caspase recruitment domain-containing protein 9 signaling in innate immunity and inflammation

(2013) Susanne Roth et al.   TRENDS IN IMMUNOLOGY

Interleukin-1β receptor expressed by modified vaccinia virus Ankara interferes with interleukin-1β activity produced in various virus-infected antigen-presenting cells

(2013) Stefan Zimmerling et al.   Virology Journal

RIG-I detects infection with liveListeriaby sensing secreted bacterial nucleic acids

(2012) Zeinab Abdullah et al.   EMBO JOURNAL

Syk Kinase-Coupled C-type Lectin Receptors Engage Protein Kinase C-δ to Elicit Card9 Adaptor-Mediated Innate Immunity

(2012) Dominikus Strasser et al.   IMMUNITY

Subversion of cytokine networks by virally encoded decoy receptors

(2012) Megan L. Epperson et al.   IMMUNOLOGICAL REVIEWS

Critical role of AIM2 in Mycobacterium tuberculosis infection

(2012) H. Saiga et al.   INTERNATIONAL IMMUNOLOGY

Treating inflammation by blocking interleukin-1 in a broad spectrum of diseases

(2012) Charles A. Dinarello et al.   NATURE REVIEWS DRUG DISCOVERY

Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

(2012) J. Wu et al.   SCIENCE

Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

(2012) L. Sun et al.   SCIENCE

DNA-PK is a DNA sensor for IRF-3-dependent innate immunity

(2012) Brian J Ferguson et al.   eLife

The Double-Stranded RNA-Binding Protein PACT Functions as a Cellular Activator of RIG-I to Facilitate Innate Antiviral Response

(2011) Kin-Hang Kok et al.   Cell Host & Microbe

Cutting Edge: Ku70 Is a Novel Cytosolic DNA Sensor That Induces Type III Rather Than Type I IFN

(2011) X. Zhang et al.   JOURNAL OF IMMUNOLOGY

MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP

(2011) L. Jin et al.   JOURNAL OF IMMUNOLOGY

The helicase DDX41 senses intracellular DNA mediated by the adaptor STING in dendritic cells

(2011) Zhiqiang Zhang et al.   NATURE IMMUNOLOGY

The MRE11 complex: starting from the ends

(2011) Travis H. Stracker et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Cytosolic DNA Triggers Inflammasome Activation in Keratinocytes in Psoriatic Lesions

(2011) Y. Dombrowski et al.   Science Translational Medicine

Pattern Recognition Receptors and Inflammation

(2010) Osamu Takeuchi et al.   CELL

The AIM2 inflammasome is essential for host defense against cytosolic bacteria and DNA viruses

(2010) Vijay A K Rathinam et al.   NATURE IMMUNOLOGY

The AIM2 inflammasome is critical for innate immunity to Francisella tularensis

(2010) Teresa Fernandes-Alnemri et al.   NATURE IMMUNOLOGY

Regulation and Function of NF-κB Transcription Factors in the Immune System

(2009) Sivakumar Vallabhapurapu et al.   Annual Review of Immunology

STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity

(2009) Hiroki Ishikawa et al.   NATURE

Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production

(2009) Hendrik Poeck et al.   NATURE IMMUNOLOGY

An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome

(2009) Tilmann Bürckstümmer et al.   NATURE IMMUNOLOGY

Rad50 Is Dispensable for the Maintenance and Viability of Postmitotic Tissues

(2008) C. A. Adelman et al.   MOLECULAR AND CELLULAR BIOLOGY

Vaccinia virus morphogenesis and dissemination

(2008) Kim L. Roberts et al.   TRENDS IN MICROBIOLOGY