Slow Replication Fork Velocity of Homologous Recombination-Defective Cells Results from Endogenous Oxidative Stress

BRCA1 and BRCA2 protect against oxidative DNA damage converted into double-strand breaks during DNA replication

(2015) Ram Fridlich et al.   DNA REPAIR

Fully validated assay for the quantification of endogenous nucleoside mono- and triphosphates using online extraction coupled with liquid chromatography–tandem mass spectrometry

(2014) Christelle Machon et al.   ANALYTICAL AND BIOANALYTICAL CHEMISTRY

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

(2014) Bret D. Freudenthal et al.   NATURE

The causes of replication stress and their consequences on genome stability and cell fate

(2014) Indiana Magdalou et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

BRCA1 interacts with Nrf2 to regulate antioxidant signaling and cell survival

(2013) Chiara Gorrini et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Spontaneous slow replication fork progression elicits mitosis alterations in homologous recombination-deficient mammalian cells

(2013) T. Wilhelm et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

APE2 is required for ATR-Chk1 checkpoint activation in response to oxidative stress

(2013) J. Willis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mre11-Dependent Degradation of Stalled DNA Replication Forks Is Prevented by BRCA2 and PARP1

(2012) S. Ying et al.   CANCER RESEARCH

Oxidative stress induces an ATM-independent senescence pathway through p38 MAPK-mediated lamin B1 accumulation

(2012) Aurelia Barascu et al.   EMBO JOURNAL

dNTP pools determine fork progression and origin usage under replication stress

(2012) Jérôme Poli et al.   EMBO JOURNAL

Double-Strand Break Repair-Independent Role for BRCA2 in Blocking Stalled Replication Fork Degradation by MRE11

(2011) Katharina Schlacher et al.   CELL

Nucleotide Deficiency Promotes Genomic Instability in Early Stages of Cancer Development

(2011) Assaf C. Bester et al.   CELL

Giant yeast cells with nonrecyclable ribonucleotide reductase

(2011) Emilie Ma et al.   MOLECULAR GENETICS AND GENOMICS

Common fragile sites: mechanisms of instability revisited

(2011) Michelle Debatisse et al.   TRENDS IN GENETICS

Pyrimidine pool imbalance induced by BLM helicase deficiency contributes to genetic instability in Bloom syndrome

(2011) Pauline Chabosseau et al.   Nature Communications

Mechanisms of dNTP supply that play an essential role in maintaining genome integrity in eukaryotic cells

(2010) Hiroyuki Niida et al.   CANCER SCIENCE

Oncogene-induced senescence: the bright and dark side of the response

(2010) Vassilis G Gorgoulis et al.   CURRENT OPINION IN CELL BIOLOGY

Nucleotide supply, not local histone acetylation, sets replication origin usage in transcribed regions

(2010) Sophie Gay et al.   EMBO REPORTS

Inhibition of S-phase progression triggered by UVA-induced ROS does not require a functional DNA damage checkpoint response in mammalian cells

(2008) Pierre-Marie Girard et al.   DNA REPAIR

A homologous recombination defect affects replication-fork progression in mammalian cells

(2007) F. Daboussi et al.   JOURNAL OF CELL SCIENCE

Concerning the Origin of Malignant Tumours by Theodor Boveri. Translated and annotated by Henry Harris

(2007) T. Boveri   JOURNAL OF CELL SCIENCE