Engineered Biomaterials for Enhanced Function of Insulin‐Secreting β‐Cell Organoids
Published 2020 View Full Article
- Home
- Publications
- Publication Search
- Publication Details
Title
Engineered Biomaterials for Enhanced Function of Insulin‐Secreting β‐Cell Organoids
Authors
Keywords
-
Journal
ADVANCED FUNCTIONAL MATERIALS
Volume -, Issue -, Pages 2000134
Publisher
Wiley
Online
2020-04-27
DOI
10.1002/adfm.202000134
References
Ask authors/readers for more resources
Related references
Note: Only part of the references are listed.- Encapsulation boosts islet-cell signature in differentiating human induced pluripotent stem cells via integrin signalling
- (2020) Thomas Aga Legøy et al. Scientific Reports
- Adipocyte-derived stem cell-based gene therapy upon adipogenic differentiation on microcarriers attenuates type 1 diabetes in mice
- (2019) Qing Fang et al. Stem Cell Research & Therapy
- Acquisition of Dynamic Function in Human Stem Cell-Derived β Cells
- (2019) Leonardo Velazco-Cruz et al. Stem Cell Reports
- A Double Fail-Safe Approach to Prevent Tumorigenesis and Select Pancreatic β Cells from Human Embryonic Stem Cells
- (2019) Mirza Muhammad Fahd Qadir et al. Stem Cell Reports
- Recapitulating endocrine cell clustering in culture promotes maturation of human stem-cell-derived β cells
- (2019) Gopika G. Nair et al. NATURE CELL BIOLOGY
- Navigating Two Roads to Glucose Normalization in Diabetes: Automated Insulin Delivery Devices and Cell Therapy
- (2019) Esther Latres et al. Cell Metabolism
- Engineering the Vasculature for Islet Transplantation
- (2019) Daniel T. Bowers et al. Acta Biomaterialia
- Oxygenation strategies for encapsulated islet and beta cell transplants
- (2019) Klearchos K. Papas et al. ADVANCED DRUG DELIVERY REVIEWS
- Heterogeneity of the Human Pancreatic Islet
- (2019) Michael P. Dybala et al. DIABETES
- Charting cellular identity during human in vitro β-cell differentiation
- (2019) Adrian Veres et al. NATURE
- Linkage Groups within Thiol–Ene Photoclickable PEG Hydrogels Control In Vivo Stability
- (2019) Michael D. Hunckler et al. Advanced Healthcare Materials
- Engineering immunomodulatory biomaterials for type 1 diabetes
- (2019) C. L. Stabler et al. Nature Reviews Materials
- Oxygen generating biomaterial improves the function and efficacy of beta cells within a macroencapsulation device
- (2019) M.M. Coronel et al. BIOMATERIALS
- A hydrogel platform for in vitro three dimensional assembly of human stem cell-derived islet cells and endothelial cells
- (2019) Punn Augsornworawat et al. Acta Biomaterialia
- Engineered materials for organoid systems
- (2019) Michael J. Kratochvil et al. Nature Reviews Materials
- The Role of the Islet Niche on Beta Cell Structure and Function
- (2019) Eckhard Lammert et al. JOURNAL OF MOLECULAR BIOLOGY
- In vivo–mimicking microfluidic perfusion culture of pancreatic islet spheroids
- (2019) Yesl Jun et al. Science Advances
- Endothelialized collagen based pseudo-islets enables tuneable subcutaneous diabetes therapy
- (2019) Alexander E. Vlahos et al. BIOMATERIALS
- Proteomic analysis of decellularized pancreatic matrix identifies collagen V as a critical regulator for islet organogenesis from human pluripotent stem cells
- (2019) Huanjing Bi et al. BIOMATERIALS
- Circadian Entrainment Triggers Maturation of Human In Vitro Islets
- (2019) Juan R. Alvarez-Dominguez et al. Cell Stem Cell
- 3D heterogeneous islet organoid generation from human embryonic stem cells using a novel engineered hydrogel platform
- (2018) Joseph Candiello et al. BIOMATERIALS
- Layer-by-layer cell coating technique using extracellular matrix facilitates rapid fabrication and function of pancreatic β-cell spheroids
- (2018) Yasunari Fukuda et al. BIOMATERIALS
- Stem Cell Therapies for Treating Diabetes: Progress and Remaining Challenges
- (2018) Julie B. Sneddon et al. Cell Stem Cell
- Extracellular matrix molecules and their potential contribution to the function of transplanted pancreatic islets
- (2018) L. Alberto Llacua et al. DIABETOLOGIA
- Molecular dynamics of pancreatic transcription factors in bioengineered humanized insulin producing neoorgan
- (2018) Sandeep Kumar Vishwakarma et al. GENE
- Endothelial and beta cell composite aggregates for improved function of a bioartificial pancreas encapsulation device
- (2018) Katarzyna Skrzypek et al. INTERNATIONAL JOURNAL OF ARTIFICIAL ORGANS
- Decellularized pancreas as a native extracellular matrix scaffold for pancreatic islet seeding and culture
- (2018) Rajesh Guruswamy Damodaran et al. Journal of Tissue Engineering and Regenerative Medicine
- Report of the Key Opinion Leaders Meeting on Stem Cell-Derived Beta Cells
- (2018) Jon Odorico et al. TRANSPLANTATION
- Replication confers β cell immaturity
- (2018) Sapna Puri et al. Nature Communications
- The journey of islet cell transplantation and future development
- (2018) Anissa Gamble et al. Islets
- Collagen type VI interaction improves human islet survival in immunoisolating microcapsules for treatment of diabetes
- (2018) L. Alberto Llacua et al. Islets
- Cluster-assembled zirconia substrates promote long-term differentiation and functioning of human islets of Langerhans
- (2018) Alessandra Galli et al. Scientific Reports
- Generation of insulin-producing cells from human induced pluripotent stem cells on PLLA/PVA nanofiber scaffold
- (2018) Seyed Ehsan Enderami et al. Artificial Cells Nanomedicine and Biotechnology
- Bioactive silk hydrogels with tunable mechanical properties
- (2018) Xue Wang et al. Journal of Materials Chemistry B
- Expansion of Adult Human Pancreatic Tissue Yields Organoids Harboring Progenitor Cells with Endocrine Differentiation Potential
- (2018) Cindy J.M. Loomans et al. Stem Cell Reports
- The EndoC-βH1 cell line is a valid model of human beta cells and applicable for screenings to identify novel drug target candidates
- (2018) Violeta Georgieva Tsonkova et al. Molecular Metabolism
- 3-D physiomimetic extracellular matrix hydrogels provide a supportive microenvironment for rodent and human islet culture
- (2018) K. Jiang et al. BIOMATERIALS
- The Role of Accessory Cells in Islet Homeostasis
- (2018) Shiue-Cheng Tang et al. Current Diabetes Reports
- Progress and potential in organoid research
- (2018) Giuliana Rossi et al. NATURE REVIEWS GENETICS
- Current Status of Stem Cell Treatment for Type I Diabetes Mellitus
- (2018) Anupama Kakkar et al. Tissue Engineering and Regenerative Medicine
- Optimization of a Polycaprolactone (PCL) Scaffold for Islet and Cellular Transplantation
- (2018) Steven Wisel et al. TRANSPLANTATION
- Extracellular matrix scaffold and hydrogel derived from decellularized and delipidized human pancreas
- (2018) Sara Dutton Sackett et al. Scientific Reports
- Neurogenin3 phosphorylation controls reprogramming efficiency of pancreatic ductal organoids into endocrine cells
- (2018) Roberta Azzarelli et al. Scientific Reports
- Local Integrin Activation in Pancreatic β Cells Targets Insulin Secretion to the Vasculature
- (2018) Wan Jun Gan et al. Cell Reports
- Islet Encapsulation
- (2018) Alexander Ulrich Ernst et al. Journal of Materials Chemistry B
- Alginate encapsulation as long-term immune protection of allogeneic pancreatic islet cells transplanted into the omental bursa of macaques
- (2018) Matthew A. Bochenek et al. Nature Biomedical Engineering
- Nanotopographical regulation of pancreatic islet-like cluster formation from human pluripotent stem cells using a gradient-pattern chip
- (2018) Jong Hyun Kim et al. Acta Biomaterialia
- Advanced Collagen-Based Biomaterials for Regenerative Biomedicine
- (2018) Kaili Lin et al. ADVANCED FUNCTIONAL MATERIALS
- Pancreatic Islet Transplantation in Humans: Recent Progress and Future Directions
- (2018) Michael R Rickels et al. ENDOCRINE REVIEWS
- Generation of functional human pancreatic organoids by transplants of embryonic stem cell derivatives in a 3D-printed tissue trapper
- (2018) Anahita Soltanian et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Closed-loop insulin delivery in suboptimally controlled type 1 diabetes: a multicentre, 12-week randomised trial
- (2018) Martin Tauschmann et al. LANCET
- Mechanosignalling via integrins directs fate decisions of pancreatic progenitors
- (2018) Anant Mamidi et al. NATURE
- Pluripotent Stem Cell-Derived Pancreatic Progenitors and β-Like Cells for Type 1 Diabetes Treatment
- (2018) Rangarajan Sambathkumar et al. PHYSIOLOGY
- Concise Review: Human Pluripotent Stem Cells for the Modeling of Pancreatic β-Cell Pathology
- (2018) Diego Balboa et al. STEM CELLS
- Generation of pancreatic β cells for treatment of diabetes: advances and challenges
- (2018) Hussain Md. Shahjalal et al. Stem Cell Research & Therapy
- Autologous fibrin scaffolds: When platelet- and plasma-derived biomolecules meet fibrin
- (2018) Eduardo Anitua et al. BIOMATERIALS
- Generation of insulin-producing cells from human adipose-derived mesenchymal stem cells on PVA scaffold by optimized differentiation protocol
- (2017) Seyed Ehsan Enderami et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Stem cell-derived organoids and their application for medical research and patient treatment
- (2017) Sina Bartfeld et al. JOURNAL OF MOLECULAR MEDICINE-JMM
- Laminin and collagen IV inclusion in immunoisolating microcapsules reduces cytokine-mediated cell death in human pancreatic islets
- (2017) L. Alberto Llacua et al. Journal of Tissue Engineering and Regenerative Medicine
- Pancreatic differentiation of induced pluripotent stem cells in activin A-grafted gelatin-poly(lactide- co -glycolide) nanoparticle scaffolds with induction of LY294002 and retinoic acid
- (2017) Yung-Chih Kuo et al. Materials Science & Engineering C-Materials for Biological Applications
- Pluripotent state transitions coordinate morphogenesis in mouse and human embryos
- (2017) Marta N. Shahbazi et al. NATURE
- Synthetic hydrogels for human intestinal organoid generation and colonic wound repair
- (2017) Ricardo Cruz-Acuña et al. NATURE CELL BIOLOGY
- Bioengineering of an Intraabdominal Endocrine Pancreas
- (2017) David A. Baidal et al. NEW ENGLAND JOURNAL OF MEDICINE
- Oxygen environment and islet size are the primary limiting factors of isolated pancreatic islet survival
- (2017) Hirotake Komatsu et al. PLoS One
- Designing a retrievable and scalable cell encapsulation device for potential treatment of type 1 diabetes
- (2017) Duo An et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets
- (2017) Alexander E. Vlahos et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Development of Islet Organoids from H9 Human Embryonic Stem Cells in Biomimetic 3D Scaffolds
- (2017) Weiwei Wang et al. STEM CELLS AND DEVELOPMENT
- Fibrin scaffold enhances function of insulin producing cells differentiated from human umbilical cord matrix-derived stem cells
- (2017) Fatemeh Seyedi et al. TISSUE & CELL
- Use of additives, scaffolds and extracellular matrix components for improvement of human pancreatic islet outcomes in vitro: A systematic review
- (2017) Natália Emerim Lemos et al. Islets
- Quantitative analysis of intra- and inter-individual variability of human beta-cell mass
- (2017) Scott K. Olehnik et al. Scientific Reports
- Take a deep breath and digest the material: organoids and biomaterials of the respiratory and digestive systems
- (2017) Briana R. Dye et al. MRS Communications
- Current and Future Perspectives on Alginate Encapsulated Pancreatic Islet
- (2017) Berit L. Strand et al. Stem Cells Translational Medicine
- The global economic burden of diabetes in adults aged 20–79 years: a cost-of-illness study
- (2017) Christian Bommer et al. Lancet Diabetes & Endocrinology
- Closed-loop insulin delivery in inpatients with type 2 diabetes: a randomised, parallel-group trial
- (2017) Hood Thabit et al. Lancet Diabetes & Endocrinology
- Localized Immunomodulatory Silk Macrocapsules for Islet-like Spheroid Formation and Sustained Insulin Production
- (2017) Manishekhar Kumar et al. ACS Biomaterials-Science & Engineering
- Type 1 diabetes mellitus
- (2017) Anastasia Katsarou et al. Nature Reviews Disease Primers
- Localized Immunomodulatory Silk Macrocapsules for Islet-like Spheroid Formation and Sustained Insulin Production
- (2017) Manishekhar Kumar et al. ACS Biomaterials Science & Engineering
- Vasculogenic hydrogel enhances islet survival, engraftment, and function in leading extrahepatic sites
- (2017) Jessica D. Weaver et al. Science Advances
- Engineering an endocrine Neo-Pancreas by repopulation of a decellularized rat pancreas with islets of Langerhans
- (2017) H. Napierala et al. Scientific Reports
- Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation
- (2017) Edward A. Phelps et al. Scientific Reports
- Capsule stiffness regulates the efficiency of pancreatic differentiation of human embryonic stem cells
- (2016) Thomas Richardson et al. Acta Biomaterialia
- The state of the art of islet transplantation and cell therapy in type 1 diabetes
- (2016) Silvia Pellegrini et al. ACTA DIABETOLOGICA
- The Human Pancreas as a Source of Protolerogenic Extracellular Matrix Scaffold for a New-generation Bioartificial Endocrine Pancreas
- (2016) Andrea Peloso et al. ANNALS OF SURGERY
- Silk matrices promote formation of insulin-secreting islet-like clusters
- (2016) Nancy Dekki Shalaly et al. BIOMATERIALS
- Transforming growth factor-beta 1 delivery from microporous scaffolds decreases inflammation post-implant and enhances function of transplanted islets
- (2016) Jeffrey M.H. Liu et al. BIOMATERIALS
- The dynamic three-dimensional culture of islet-like clusters in decellularized liver scaffolds
- (2016) Pengcheng Zhou et al. CELL AND TISSUE RESEARCH
- Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold
- (2016) Dora M. Berman et al. DIABETES
- The quest to make fully functional human pancreatic beta cells from embryonic stem cells: climbing a mountain in the clouds
- (2016) James D. Johnson DIABETOLOGIA
- PVA-based hydrogels for tissue engineering: A review
- (2016) Anuj Kumar et al. International Journal of Polymeric Materials and Polymeric Biomaterials
- Extracellular matrix components supporting human islet function in alginate-based immunoprotective microcapsules for treatment of diabetes
- (2016) Alberto Llacua et al. JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART A
- Cell polarity defines three distinct domains in pancreatic β-cells
- (2016) Wan J. Gan et al. JOURNAL OF CELL SCIENCE
- Designer matrices for intestinal stem cell and organoid culture
- (2016) Nikolce Gjorevski et al. NATURE
- Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice
- (2016) Arturo J Vegas et al. NATURE MEDICINE
- Advances in islet encapsulation technologies
- (2016) Tejal Desai et al. NATURE REVIEWS DRUG DISCOVERY
- Impact of islet architecture on β-cell heterogeneity, plasticity and function
- (2016) Sara S. Roscioni et al. Nature Reviews Endocrinology
- Clinical pancreatic islet transplantation
- (2016) A. M. James Shapiro et al. Nature Reviews Endocrinology
- Enzymes for Pancreatic Islet Isolation Impact Chemokine-Production and Polarization of Insulin-Producing β-Cells with Reduced Functional Survival of Immunoisolated Rat Islet-Allografts as a Consequence
- (2016) Paul de Vos et al. PLoS One
- Oxygen-Generating Biomaterials: A New, Viable Paradigm for Tissue Engineering?
- (2016) Mazaher Gholipourmalekabadi et al. TRENDS IN BIOTECHNOLOGY
- Pancreatic islet blood flow and its measurement
- (2016) Leif Jansson et al. UPSALA JOURNAL OF MEDICAL SCIENCES
- Generation of stem cell-derived β-cells from patients with type 1 diabetes
- (2016) Jeffrey R. Millman et al. Nature Communications
- Human islets contain four distinct subtypes of β cells
- (2016) Craig Dorrell et al. Nature Communications
- β-Cell regeneration through the transdifferentiation of pancreatic cells: Pancreatic progenitor cells in the pancreas
- (2016) Hyo-Sup Kim et al. Journal of Diabetes Investigation
- PVA-based hydrogels for tissue engineering: A review
- (2016) Anuj Kumar et al. International Journal of Polymeric Materials and Polymeric Biomaterials
- Lung-Derived Microscaffolds Facilitate Diabetes Reversal after Mouse and Human Intraperitoneal Islet Transplantation
- (2016) Nasser Abualhassan et al. PLoS One
- Pancreatic beta cell lines and their applications in diabetes mellitus research
- (2016) Masa Skelin ALTEX-Alternatives to Animal Experimentation
- Evolving insights in cell–matrix interactions: Elucidating how non-soluble properties of the extracellular niche direct stem cell fate
- (2015) Nick J. Walters et al. Acta Biomaterialia
- Human pluripotent stem cell based islet models for diabetes research
- (2015) Diego Balboa et al. BEST PRACTICE & RESEARCH CLINICAL ENDOCRINOLOGY & METABOLISM
- Impact of an autologous oxygenating matrix culture system on rat islet transplantation outcome
- (2015) A. Schaschkow et al. BIOMATERIALS
- Islet formation in mice and men: lessons for the generation of functional insulin-producing β-cells from human pluripotent stem cells
- (2015) Gopika Nair et al. CURRENT OPINION IN GENETICS & DEVELOPMENT
- New insights into the architecture of the islet of Langerhans: a focused cross-species assessment
- (2015) Rafael Arrojo e Drigo et al. DIABETOLOGIA
- Controlled induction of human pancreatic progenitors produces functional beta-like cells in vitro
- (2015) H. A. Russ et al. EMBO JOURNAL
- Three-dimensional culture of mouse pancreatic islet on a liver-derived perfusion-decellularized bioscaffold for potential clinical application
- (2015) Tianxin Xu et al. JOURNAL OF BIOMATERIALS APPLICATIONS
- Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis
- (2015) Nduka O. Enemchukwu et al. JOURNAL OF CELL BIOLOGY
- Human Islet Morphology Revisited
- (2015) Susan Bonner-Weir et al. JOURNAL OF HISTOCHEMISTRY & CYTOCHEMISTRY
- Extracellular Matrix and Growth Factors Improve the Efficacy of Intramuscular Islet Transplantation
- (2015) Haruyuki Tsuchiya et al. PLoS One
- Progress in material design for biomedical applications
- (2015) Mark W. Tibbitt et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Three-dimensional differentiation of bone marrow-derived mesenchymal stem cells into insulin-producing cells
- (2015) Layasadat Khorsandi et al. TISSUE & CELL
- Controlled Release of Dexamethasone from Organosilicone Constructs for Local Modulation of Inflammation in Islet Transplantation
- (2015) Jessica D. Weaver et al. TISSUE ENGINEERING PART A
- Beta Cells Secrete Significant and Regulated Levels of Insulin for Long Periods when Seeded onto Acellular Micro-Scaffolds
- (2015) Ronit Vogt Sionov et al. TISSUE ENGINEERING PART A
- Fibrin, a Scaffold Material for Islet Transplantation and Pancreatic Endocrine Tissue Engineering
- (2015) Matthew Riopel et al. TISSUE ENGINEERING PART B-REVIEWS
- Accelerated Maturation of Human Stem Cell-Derived Pancreatic Progenitor Cells into Insulin-Secreting Cells in Immunodeficient Rats Relative to Mice
- (2015) Jennifer E. Bruin et al. Stem Cell Reports
- Type 2 diabetes mellitus
- (2015) Ralph A. DeFronzo et al. Nature Reviews Disease Primers
- Enhancing Human Islet Transplantation by Localized Release of Trophic Factors From PLG Scaffolds
- (2014) K. A. Hlavaty et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Generation of Functional Human Pancreatic β Cells In Vitro
- (2014) Felicia W. Pagliuca et al. CELL
- Stem Cells to Insulin Secreting Cells: Two Steps Forward and Now a Time to Pause?
- (2014) Jake A. Kushner et al. Cell Stem Cell
- Cadherin Engagement Improves Insulin Secretion of Single Human β-Cells
- (2014) Geraldine Parnaud et al. DIABETES
- Insulin secretion from beta cells in intact mouse islets is targeted towards the vasculature
- (2014) Jiun T. Low et al. DIABETOLOGIA
- Collagen matrix support of pancreatic islet survival and function
- (2014) Matthew Riopel Frontiers in Bioscience-Landmark
- Improved physiological properties of gravity-enforced reassembled rat and human pancreatic pseudo-islets
- (2014) R. A. Zuellig et al. Journal of Tissue Engineering and Regenerative Medicine
- Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells
- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
- Alginate Encapsulation of Human Embryonic Stem Cells to Enhance Directed Differentiation to Pancreatic Islet-Like Cells
- (2014) Thomas Richardson et al. TISSUE ENGINEERING PART A
- Compliant 3D Microenvironment Improves β-Cell Cluster Insulin Expression Through Mechanosensing and β-Catenin Signaling
- (2014) Crystal E. Nyitray et al. TISSUE ENGINEERING PART A
- Scaffold Architecture Controls Insulinoma Clustering, Viability, and Insulin Production
- (2014) Britani N. Blackstone et al. TISSUE ENGINEERING PART A
- In vitro reconstitution of pancreatic islets
- (2014) Nobuhiko Kojima Organogenesis
- The effect of endothelial cells on hESC-derived pancreatic progenitors in a 3D environment
- (2014) Anat Weizman et al. Biomaterials Science
- Nanotopography – potential relevance in the stem cell niche
- (2014) Lesley-Anne Turner et al. Biomaterials Science
- Fibrin improves beta (INS-1) cell function, proliferation and survival through integrin αvβ3
- (2013) Matthew Riopel et al. Acta Biomaterialia
- Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes
- (2013) Edward A. Phelps et al. BIOMATERIALS
- Porcine pancreas extracellular matrix as a platform for endocrine pancreas bioengineering
- (2013) Sayed-Hadi Mirmalek-Sani et al. BIOMATERIALS
- Perfusion-decellularized pancreas as a natural 3D scaffold for pancreatic tissue and whole organ engineering
- (2013) Saik-Kia Goh et al. BIOMATERIALS
- Macroporous Three-Dimensional PDMS Scaffolds for Extrahepatic Islet Transplantation
- (2013) Eileen Pedraza et al. CELL TRANSPLANTATION
- Engineering synthetic hydrogel microenvironments to instruct stem cells
- (2013) Murat Guvendiren et al. CURRENT OPINION IN BIOTECHNOLOGY
- Engineering a local microenvironment for pancreatic islet replacement
- (2013) Maria M Coronel et al. CURRENT OPINION IN BIOTECHNOLOGY
- Artificial three-dimensional niches deconstruct pancreas development in vitro
- (2013) C. Greggio et al. DEVELOPMENT
- 1 integrin is a crucial regulator of pancreatic -cell expansion
- (2013) G. R. Diaferia et al. DEVELOPMENT
- Unlimited in vitro expansion of adult bi-potent pancreas progenitors through the Lgr5/R-spondin axis
- (2013) Meritxell Huch et al. EMBO JOURNAL
- Collagen-chitosan-laminin hydrogels for the delivery of insulin-producing tissue
- (2013) Kimberly McEwan et al. Journal of Tissue Engineering and Regenerative Medicine
- Connexin 36, a key element in pancreatic beta cell function
- (2013) E. Martha Pérez-Armendariz NEUROPHARMACOLOGY
- Reconstituting pancreas development from purified progenitor cells reveals genes essential for islet differentiation
- (2013) T. Sugiyama et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Growing Self-Organizing Mini-Guts from a Single Intestinal Stem Cell: Mechanism and Applications
- (2013) T. Sato et al. SCIENCE
- Collagen IV-Modified Scaffolds Improve Islet Survival and Function and Reduce Time to Euglycemia
- (2013) Woon Teck Yap et al. TISSUE ENGINEERING PART A
- Enhanced Survival and Function of Islet-Like Clusters Differentiated from Adipose Stem Cells on a Three-Dimensional Natural Polymeric Scaffold: An In Vitro Study
- (2013) Neena Aloysious et al. TISSUE ENGINEERING PART A
- Young porcine endocrine pancreatic islets cultured in fibrin show improved resistance toward hydrogen peroxide
- (2013) Carina Kuehn et al. Islets
- Alginate-Based Biomaterials for Regenerative Medicine Applications
- (2013) Jinchen Sun et al. Materials
- Microbead-based biomimetic synthetic neighbors enhance survival and function of rat pancreatic β-cells
- (2013) Wei Li et al. Scientific Reports
- Evaluation of islets derived from human fetal pancreatic progenitor cells in diabetes treatment
- (2013) Wen-Jian Zhang et al. Stem Cell Research & Therapy
- Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells
- (2013) Jonghyeob Lee et al. eLife
- Engineered VEGF-releasing PEG–MAL hydrogel for pancreatic islet vascularization
- (2013) Edward A. Phelps et al. Drug Delivery and Translational Research
- Three-Dimensional Scaffolds Reduce Islet Amyloid Formation and Enhance Survival and Function of Cultured Human Islets
- (2012) Yun Zhang et al. AMERICAN JOURNAL OF PATHOLOGY
- Enhanced function of pancreatic islets co-encapsulated with ECM proteins and mesenchymal stromal cells in a silk hydrogel
- (2012) Nicolynn E. Davis et al. BIOMATERIALS
- Porous Scaffolds Support Extrahepatic Human Islet Transplantation, Engraftment, and Function in Mice
- (2012) Romie F. Gibly et al. CELL TRANSPLANTATION
- Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
- (2012) A. Rezania et al. DIABETES
- The Peri-islet Basement Membrane, a Barrier to Infiltrating Leukocytes in Type 1 Diabetes in Mouse and Human
- (2012) E. Korpos et al. DIABETES
- Distinctions Between the Islets of Mice and Men: Implications for New Therapies for Type 1 and 2 Diabetes
- (2012) Claresa Levetan et al. Endocrine Practice
- Synthesis of macroporous poly(dimethylsiloxane) scaffolds for tissue engineering applications
- (2012) Eileen Pedraza et al. JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION
- Matrix nanotopography as a regulator of cell function
- (2012) Deok-Ho Kim et al. JOURNAL OF CELL BIOLOGY
- Functional beta-cell maturation is marked by an increased glucose threshold and by expression of urocortin 3
- (2012) Barak Blum et al. NATURE BIOTECHNOLOGY
- Functional engraftment of colon epithelium expanded in vitro from a single adult Lgr5+ stem cell
- (2012) Shiro Yui et al. NATURE MEDICINE
- Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture
- (2012) Sarita Negi et al. PLoS One
- Preventing hypoxia-induced cell death in beta cells and islets via hydrolytically activated, oxygen-generating biomaterials
- (2012) E. Pedraza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- What Is the Greatest Regulatory Challenge in the Translation of Biomaterials to the Clinic?
- (2012) G. D. Prestwich et al. Science Translational Medicine
- Moving from static to dynamic complexity in hydrogel design
- (2012) Jason A. Burdick et al. Nature Communications
- Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery
- (2011) Edward A. Phelps et al. ADVANCED MATERIALS
- The role of short synthetic adhesion peptides in regenerative medicine; The debate
- (2011) David F. Williams BIOMATERIALS
- Evolving the use of peptides as components of biomaterials
- (2011) Joel H. Collier et al. BIOMATERIALS
- The role of ECM proteins and protein fragments in guiding cell behavior in regenerative medicine
- (2011) Thomas H. Barker BIOMATERIALS
- PEG hydrogels formed by thiol-ene photo-click chemistry and their effect on the formation and recovery of insulin-secreting cell spheroids
- (2011) Chien-Chi Lin et al. BIOMATERIALS
- An overview of tissue and whole organ decellularization processes
- (2011) Peter M. Crapo et al. BIOMATERIALS
- Perfluorodecalin-enriched fibrin matrix for human islet culture
- (2011) Elisa Maillard et al. BIOMATERIALS
- Advancing islet transplantation: from engraftment to the immune response
- (2011) R. F. Gibly et al. DIABETOLOGIA
- Gap junctions and other mechanisms of cell-cell communication regulate basal insulin secretion in the pancreatic islet
- (2011) R. K. P. Benninger et al. JOURNAL OF PHYSIOLOGY-LONDON
- Tailoring material properties of a nanofibrous extracellular matrix derived hydrogel
- (2011) Todd D Johnson et al. NANOTECHNOLOGY
- Cell-cell communication mimicry with poly(ethylene glycol) hydrogels for enhancing -cell function
- (2011) C.-C. Lin et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Matrix Components and Scaffolds for Sustained Islet Function
- (2011) Jennifer Y.C. Cheng et al. TISSUE ENGINEERING PART B-REVIEWS
- Function and Viability of Human Islets Encapsulated in Alginate Sheets: In Vitro and in Vivo Culture
- (2011) M. Lamb et al. TRANSPLANTATION PROCEEDINGS
- Role of islet structure and cellular interactions in the control of insulin secretion
- (2011) Catriona Kelly et al. Islets
- The in vivo performance of polyvinyl alcohol macro-encapsulated islets
- (2010) Zhi Qi et al. BIOMATERIALS
- Bioactive modification of poly(ethylene glycol) hydrogels for tissue engineering
- (2010) Junmin Zhu BIOMATERIALS
- Long-term in vitro human pancreatic islet culture using three-dimensional microfabricated scaffolds
- (2010) Jamal T. Daoud et al. BIOMATERIALS
- Unique Arrangement of - and -Cells in Human Islets of Langerhans
- (2010) D. Bosco et al. DIABETES
- Multiple uses of basement membrane-like matrix (BME/Matrigel) in vitro and in vivo with cancer cells
- (2010) Gabriel Benton et al. INTERNATIONAL JOURNAL OF CANCER
- Pseudoislets in stirred-suspension culture exhibit enhanced cell survival, propagation and insulin secretion
- (2010) Lye T. Lock et al. JOURNAL OF BIOTECHNOLOGY
- Fibroblast populated collagen matrix promotes islet survival and reduces the number of islets required for diabetes reversal
- (2010) Reza B. Jalili et al. JOURNAL OF CELLULAR PHYSIOLOGY
- Quantitative analysis of cell composition and purity of human pancreatic islet preparations
- (2010) Anna Pisania et al. LABORATORY INVESTIGATION
- Bioartificial matrices for therapeutic vascularization
- (2010) Edward A. Phelps et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Matrigel: A complex protein mixture required for optimal growth of cell culture
- (2010) Chris S. Hughes et al. PROTEOMICS
- Encapsulation of Pancreatic Islets Within Nano-Thin Functional Polyethylene Glycol Coatings for Enhanced Insulin Secretion
- (2010) Seda Kizilel et al. TISSUE ENGINEERING PART A
- Preservation of Islet Survival by Upregulating α3 Integrin Signaling: The Importance of 3-Dimensional Islet Culture in Basement Membrane Extract
- (2010) Y. Zhao et al. TRANSPLANTATION PROCEEDINGS
- ‘Giving and taking’: endothelial and β-cells in the islets of Langerhans
- (2010) Daniel Eberhard et al. TRENDS IN ENDOCRINOLOGY AND METABOLISM
- Pancreatic islet plasticity: Interspecies comparison of islet architecture and composition
- (2010) Donald J. Steiner et al. Islets
- Quantitative Monitoring of Insulin Secretion from Single Islets of Langerhans in Parallel on a Microfluidic Chip
- (2009) John F. Dishinger et al. ANALYTICAL CHEMISTRY
- Glucagon-Like Peptide-1 Functionalized PEG Hydrogels Promote Survival and Function of Encapsulated Pancreatic β-Cells
- (2009) Chien-Chi Lin et al. BIOMACROMOLECULES
- Islet assessment for transplantation
- (2009) Klearchos K Papas et al. Current Opinion in Organ Transplantation
- Impaired Insulin Exocytosis in Neural Cell Adhesion Molecule−/−Mice Due to Defective Reorganization of the Submembrane F-Actin Network
- (2009) Charlotta S. Olofsson et al. ENDOCRINOLOGY
- Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties
- (2009) April M. Kloxin et al. SCIENCE
- Entrapped Collagen Type 1 Promotes Differentiation of Embryonic Pancreatic Precursor Cells into Glucose-Responsive β-Cells When Cultured in Three-Dimensional PEG Hydrogels
- (2009) Mariah N. Mason et al. TISSUE ENGINEERING PART A
- Long-Term Survival of Nonhuman Primate Islets Implanted in an Omental Pouch on a Biodegradable Scaffold
- (2008) D. M. Berman et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Unique basement membrane structure of human pancreatic islets: implications for β-cell growth and differentiation
- (2008) T. Otonkoski et al. DIABETES OBESITY & METABOLISM
- Pancreatic β-cell mass in European subjects with type 2 diabetes
- (2008) J. Rahier et al. DIABETES OBESITY & METABOLISM
- Insulin secretion from human beta cells is heterogeneous and dependent on cell-to-cell contacts
- (2008) A. Wojtusciszyn et al. DIABETOLOGIA
- Microfluidic device for multimodal characterization of pancreatic islets
- (2008) Javeed Shaikh Mohammed et al. LAB ON A CHIP
- Hydrogel encapsulation environments functionalized with extracellular matrix interactions increase islet insulin secretion
- (2008) Laney M. Weber et al. MATRIX BIOLOGY
- Pancreatic endoderm derived from human embryonic stem cells generates glucose-responsive insulin-secreting cells in vivo
- (2008) Evert Kroon et al. NATURE BIOTECHNOLOGY
- Cell–Matrix Interactions Improve β-Cell Survival and Insulin Secretion in Three-Dimensional Culture
- (2008) Laney M. Weber et al. TISSUE ENGINEERING PART A
- Selective β-Cell Differentiation of Dissociated Embryonic Pancreatic Precursor Cells Cultured in Synthetic Polyethylene Glycol Hydrogels
- (2008) Mariah N. Mason et al. TISSUE ENGINEERING PART A
- Fibrin: A Versatile Scaffold for Tissue Engineering Applications
- (2008) Tamer A.E. Ahmed et al. TISSUE ENGINEERING PART B-REVIEWS
- Extracellular Matrix Protein-Coated Scaffolds Promote the Reversal of Diabetes After Extrahepatic Islet Transplantation
- (2008) David M. Salvay et al. TRANSPLANTATION
Add your recorded webinar
Do you already have a recorded webinar? Grow your audience and get more views by easily listing your recording on Peeref.
Upload NowAsk a Question. Answer a Question.
Quickly pose questions to the entire community. Debate answers and get clarity on the most important issues facing researchers.
Get Started