Modular tissue engineering for the vascularization of subcutaneously transplanted pancreatic islets

Colony stimulating factor-1 receptor is a central component of the foreign body response to biomaterial implants in rodents and non-human primates

(2017) Joshua C. Doloff et al.   NATURE MATERIALS

Three-Dimensional Optical Mapping of Nanoparticle Distribution in Intact Tissues

(2016) Shrey Sindhwani et al.   ACS Nano

Effect of methacrylic acid beads on the sonic hedgehog signaling pathway and macrophage polarization in a subcutaneous injection mouse model

(2016) Alexandra Lisovsky et al.   BIOMATERIALS

Clarifying intact 3D tissues on a microfluidic chip for high-throughput structural analysis

(2016) Yih Yang Chen et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Coculturing Human Islets with Proangiogenic Support Cells to Improve Islet Revascularization at the Subcutaneous Transplantation Site

(2016) Mijke Buitinga et al.   TISSUE ENGINEERING PART A

Harnessing the Foreign Body Reaction in Marginal Mass Device-less Subcutaneous Islet Transplantation in Mice

(2016) Andrew R. Pepper et al.   TRANSPLANTATION

A prevascularized subcutaneous device-less site for islet and cellular transplantation

(2015) Andrew R Pepper et al.   NATURE BIOTECHNOLOGY

A Method for Performing Islet Transplantation Using Tissue-Engineered Sheets of Islets and Mesenchymal Stem Cells

(2015) Masataka Hirabaru et al.   TISSUE ENGINEERING PART C-METHODS

Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device

(2015) Andrew R. Pepper et al.   TRANSPLANTATION

Long-Term Allogeneic Islet Graft Survival in Prevascularized Subcutaneous Sites Without Immunosuppressive Treatment

(2014) N. M. Luan et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Single-Cell Phenotyping within Transparent Intact Tissue through Whole-Body Clearing

(2014) Bin Yang et al.   CELL

Islet Microenvironment, Modulated by Vascular Endothelial Growth Factor-A Signaling, Promotes β Cell Regeneration

(2014) Marcela Brissova et al.   Cell Metabolism

Phenotyping animal models of diabetic neuropathy: a consensus statement of the diabetic neuropathy study group of the EASD (Neurodiab)

(2014) G.J. Biessels et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Advanced CLARITY for rapid and high-resolution imaging of intact tissues

(2014) Raju Tomer et al.   Nature Protocols

Co-Transplantation of Endothelial Progenitor Cells and Pancreatic Islets to Induce Long-Lasting Normoglycemia in Streptozotocin-Treated Diabetic Rats

(2014) Paola Quaranta et al.   PLoS One

M2 macrophages promote beta-cell proliferation by up-regulation of SMAD7

(2014) Xiangwei Xiao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mutual effect of subcutaneously transplanted human adipose-derived stem cells and pancreatic islets within fibrin gel

(2013) Suk Ho Bhang et al.   BIOMATERIALS

Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes

(2013) Edward A. Phelps et al.   BIOMATERIALS

Revascularization of Transplanted Pancreatic Islets and Role of the Transplantation Site

(2013) Andrew R. Pepper et al.   Clinical & Developmental Immunology

Bioengineered Sites for Islet Cell Transplantation

(2013) Sophie Vériter et al.   Current Diabetes Reports

Engineering a local microenvironment for pancreatic islet replacement

(2013) Maria M Coronel et al.   CURRENT OPINION IN BIOTECHNOLOGY

Resolution of inflammation: an integrated view

(2013) Almudena Ortega-Gómez et al.   EMBO Molecular Medicine

Collagen IV-Modified Scaffolds Improve Islet Survival and Function and Reduce Time to Euglycemia

(2013) Woon Teck Yap et al.   TISSUE ENGINEERING PART A

Ex Vivo Expanded Human Regulatory T Cells Can Prolong Survival of a Human Islet Allograft in a Humanized Mouse Model

(2013) Douglas C. Wu et al.   TRANSPLANTATION

Bioengineering a highly vascularized matrix for the ectopic transplantation of islets

(2013) Cara Ellis et al.   Islets

Update on Islet Transplantation

(2013) M. McCall et al.   Cold Spring Harbor Perspectives in Medicine

VEGF-A recruits a proangiogenic MMP-9-delivering neutrophil subset that induces angiogenesis in transplanted hypoxic tissue

(2012) G. Christoffersson et al.   BLOOD

Adoptive Transfer of Immunomodulatory M2 Macrophages Prevents Type 1 Diabetes in NOD Mice

(2012) R. Parsa et al.   DIABETES

Analysis of Beta-Cell Gene Expression Reveals Inflammatory Signaling and Evidence of Dedifferentiation following Human Islet Isolation and Culture

(2012) Sarita Negi et al.   PLoS One

Improvement of islet function in a bioartificial pancreas by enhanced oxygen supply and growth hormone releasing hormone agonist

(2012) B. Ludwig et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cotransplantation of Adipose-Derived Mesenchymal Stromal Cells and Endothelial Cells in a Modular Construct Drives Vascularization in SCID/bg Mice

(2012) Mark J. Butler et al.   TISSUE ENGINEERING PART A

Strategies toward single-donor islets of Langerhans transplantation

(2011) A.M. James Shapiro   Current Opinion in Organ Transplantation

Donor Islet Endothelial Cells in Pancreatic Islet Revascularization

(2011) D. Nyqvist et al.   DIABETES

Bone Marrow-Derived Mesenchymal Stromal Cells Enhance Chimeric Vessel Development Driven by Endothelial Cell-Coated Microtissues

(2011) Michael Dean Chamberlain et al.   TISSUE ENGINEERING PART A

Human Immune System Development and Rejection of Human Islet Allografts in Spontaneously Diabetic NOD-Rag1null IL2r null Ins2Akita Mice

(2010) M. A. Brehm et al.   DIABETES

Bone Marrow Cell Cotransplantation With Islets Improves Their Vascularization and Function

(2010) Naoaki Sakata et al.   TRANSPLANTATION

Preservation of Islet Survival by Upregulating α3 Integrin Signaling: The Importance of 3-Dimensional Islet Culture in Basement Membrane Extract

(2010) Y. Zhao et al.   TRANSPLANTATION PROCEEDINGS

A Practical Guide to Rodent Islet Isolation and Assessment

(2009) Jeffrey D. Carter et al.   BIOLOGICAL PROCEDURES ONLINE

Creation of a Rich Subcutaneous Vascular Network with Implanted Adipose Tissue–Derived Stromal Cells and Adipose Tissue Enhances Subcutaneous Grafting of Islets in Diabetic Mice

(2009) Yuichi Fumimoto et al.   TISSUE ENGINEERING PART C-METHODS

Long-Term Insulin-Independence After Allogeneic Islet Transplantation for Type 1 Diabetes: Over the 10-Year Mark

(2008) T. Berney et al.   AMERICAN JOURNAL OF TRANSPLANTATION

Plasma–Fibroblast Gel as Scaffold for Islet Transplantation

(2008) Marcos Perez-Basterrechea et al.   TISSUE ENGINEERING PART A