Progress in material design for biomedical applications

Nanofibrous Hydrogels with Spatially Patterned Biochemical Signals to Control Cell Behavior

(2015) Ryan J. Wade et al.   ADVANCED MATERIALS

Direct 3D Printing of Shear-Thinning Hydrogels into Self-Healing Hydrogels

(2015) Christopher B. Highley et al.   ADVANCED MATERIALS

Adaptable Hydrogel Networks with Reversible Linkages for Tissue Engineering

(2015) Huiyuan Wang et al.   ADVANCED MATERIALS

Protein-Induced Supramolecular Disassembly of Amphiphilic Polypeptide Nanoassemblies

(2015) Mijanur Rahaman Molla et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Fractal heterogeneity in minimal matrix models of scars modulates stiff-niche stem-cell responses via nuclear exit of a mechanorepressor

(2015) P. C. Dave P. Dingal et al.   NATURE MATERIALS

Pore Interconnectivity Influences Growth Factor-Mediated Vascularization in Sphere-Templated Hydrogels

(2015) Sami I. Somo et al.   TISSUE ENGINEERING PART C-METHODS

Collagen Scaffolds Incorporating Coincident Gradations of Instructive Structural and Biochemical Cues for Osteotendinous Junction Engineering

(2015) Steven R. Caliari et al.   Advanced Healthcare Materials

Nanoparticle-Hydrogel Composites: Concept, Design, and Applications of These Promising, Multi-Functional Materials

(2015) Praveen Thoniyot et al.   Advanced Science

3D Bioprinting of Vascularized, Heterogeneous Cell-Laden Tissue Constructs

(2014) David B. Kolesky et al.   ADVANCED MATERIALS

Biomedical Applications of Supramolecular Systems Based on Host–Guest Interactions

(2014) Xing Ma et al.   CHEMICAL REVIEWS

Matricellular proteins and biomaterials

(2014) Aaron H. Morris et al.   MATRIX BIOLOGY

Advances in nanofibrous scaffolds for biomedical applications: From electrospinning to self-assembly

(2014) Ryan J. Wade et al.   Nano Today

Injectable and bioresponsive hydrogels for on-demand matrix metalloproteinase inhibition

(2014) Brendan P. Purcell et al.   NATURE MATERIALS

Light-triggered in vivo activation of adhesive peptides regulates cell adhesion, inflammation and vascularization of biomaterials

(2014) Ted T. Lee et al.   NATURE MATERIALS

Mechanical memory and dosing influence stem cell fate

(2014) Chun Yang et al.   NATURE MATERIALS

In vivo endothelial siRNA delivery using polymeric nanoparticles with low molecular weight

(2014) James E. Dahlman et al.   Nature Nanotechnology

mRNA-based therapeutics — developing a new class of drugs

(2014) Ugur Sahin et al.   NATURE REVIEWS DRUG DISCOVERY

Ultrasound-triggered disruption and self-healing of reversibly cross-linked hydrogels for drug delivery and enhanced chemotherapy

(2014) Nathaniel Huebsch et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

In Vivo Applications of Electrospun Tissue-Engineered Vascular Grafts: A Review

(2014) Kevin A. Rocco et al.   TISSUE ENGINEERING PART B-REVIEWS

Guided and magnetic self-assembly of tunable magnetoceptive gels

(2014) S. Tasoglu et al.   Nature Communications

Synthesis and orthogonal photopatterning of hyaluronic acid hydrogels with thiol-norbornene chemistry

(2013) William M. Gramlich et al.   BIOMATERIALS

Efficiency of siRNA delivery by lipid nanoparticles is limited by endocytic recycling

(2013) Gaurav Sahay et al.   NATURE BIOTECHNOLOGY

Zwitterionic hydrogels implanted in mice resist the foreign-body reaction

(2013) Lei Zhang et al.   NATURE BIOTECHNOLOGY

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

Engineering synthetic vaccines using cues from natural immunity

(2013) Darrell J. Irvine et al.   NATURE MATERIALS

Delivery materials for siRNA therapeutics

(2013) Rosemary Kanasty et al.   NATURE MATERIALS

Safety and Efficacy of RNAi Therapy for Transthyretin Amyloidosis

(2013) Teresa Coelho et al.   NEW ENGLAND JOURNAL OF MEDICINE

Hydrogels that mimic developmentally relevant matrix and N-cadherin interactions enhance MSC chondrogenesis

(2013) L. Bian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

(2013) P. L. Rodriguez et al.   SCIENCE

Stimuli-responsive polymers: Biomedical applications and challenges for clinical translation

(2012) Allan S. Hoffman   ADVANCED DRUG DELIVERY REVIEWS

Three-Dimensional Biomimetic Patterning in Hydrogels to Guide Cellular Organization

(2012) James C. Culver et al.   ADVANCED MATERIALS

Recent Insights Into the Biomedical Applications of Shape-memory Polymers

(2012) Maria C. Serrano et al.   MACROMOLECULAR BIOSCIENCE

Rapid casting of patterned vascular networks for perfusable engineered three-dimensional tissues

(2012) Jordan S. Miller et al.   NATURE MATERIALS

Dual Delivery of Hepatocyte and Vascular Endothelial Growth Factors via a Protease-Degradable Hydrogel Improves Cardiac Function in Rats

(2012) Apoorva S. Salimath et al.   PLoS One

Dynamic Microenvironments: The Fourth Dimension

(2012) M. W. Tibbitt et al.   Science Translational Medicine

Stiffening hydrogels to probe short- and long-term cellular responses to dynamic mechanics

(2012) Murat Guvendiren et al.   Nature Communications

Bioorthogonal Click Chemistry: An Indispensable Tool to Create Multifaceted Cell Culture Scaffolds

(2012) Malar A. Azagarsamy et al.   ACS Macro Letters

Surfaces That Sequester Serum-Borne Heparin Amplify Growth Factor Activity

(2011) Gregory A. Hudalla et al.   ADVANCED MATERIALS

Photoreversible Patterning of Biomolecules within Click-Based Hydrogels

(2011) Cole A. DeForest et al.   ANGEWANDTE CHEMIE-INTERNATIONAL EDITION

The effect of anisotropic collagen-GAG scaffolds and growth factor supplementation on tendon cell recruitment, alignment, and metabolic activity

(2011) Steven R. Caliari et al.   BIOMATERIALS

Controlled activation of morphogenesis to generate a functional human microvasculature in a synthetic matrix

(2011) D. Hanjaya-Putra et al.   BLOOD

Injectable and biodegradable hydrogels: gelation, biodegradation and biomedical applications

(2011) Yulin Li et al.   CHEMICAL SOCIETY REVIEWS

Biomedical applications of biodegradable polymers

(2011) Bret D. Ulery et al.   JOURNAL OF POLYMER SCIENCE PART B-POLYMER PHYSICS

Biomimetic Approaches to Control Soluble Concentration Gradients in Biomaterials

(2011) Eric H. Nguyen et al.   MACROMOLECULAR BIOSCIENCE

Spatially controlled simultaneous patterning of multiple growth factors in three-dimensional hydrogels

(2011) Ryan G. Wylie et al.   NATURE MATERIALS

Photoactivated Composite Biomaterial for Soft Tissue Restoration in Rodents and in Humans

(2011) A. T. Hillel et al.   Science Translational Medicine

Emerging area: biomaterials that mimic and exploit protein motion

(2011) William L. Murphy   Soft Matter

From 3D cell culture to organs-on-chips

(2011) Dongeun Huh et al.   TRENDS IN CELL BIOLOGY

Facile formation of dynamic hydrogel microspheres for triggered growth factor delivery

(2010) William J. King et al.   Acta Biomaterialia

A microcomposite hydrogel for repeated on-demand ultrasound-triggered drug delivery

(2010) Hila Epstein-Barash et al.   BIOMATERIALS

Hydrogels with time-dependent material properties enhance cardiomyocyte differentiation in vitro

(2010) Jennifer L. Young et al.   BIOMATERIALS

High-throughput methods to define complex stem cell niches

(2010) Stefan Kobel et al.   BIOTECHNIQUES

Shape-memory polymers as a technology platform for biomedical applications

(2010) Andreas Lendlein et al.   Expert Review of Medical Devices

Review Paper: Absorbable Polymeric Surgical Sutures: Chemistry, Production, Properties, Biodegradability, and Performance

(2010) Chennakkattu Krishna Sadasivan Pillai et al.   JOURNAL OF BIOMATERIALS APPLICATIONS

Coronary Stents

(2010) Scot Garg et al.   JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY

Affinity-Based Drug Delivery

(2010) Nick X. Wang et al.   MACROMOLECULAR BIOSCIENCE

Proangiogenic scaffolds as functional templates for cardiac tissue engineering

(2010) L. R. Madden et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Substrate Elasticity Regulates Skeletal Muscle Stem Cell Self-Renewal in Culture

(2010) P. M. Gilbert et al.   SCIENCE

Dynamic Hydrogels: Switching of 3D Microenvironments Using Two-Component Naturally Derived Extracellular Matrices

(2009) Brian M. Gillette et al.   ADVANCED MATERIALS

The relationship between fibroblast growth and the dynamic stiffnesses of a DNA crosslinked hydrogel

(2009) Frank X. Jiang et al.   BIOMATERIALS

In situ elasticity modulation with dynamic substrates to direct cell phenotype

(2009) April M. Kloxin et al.   BIOMATERIALS

Hydrogels as extracellular matrix mimics for 3D cell culture

(2009) Mark W. Tibbitt et al.   BIOTECHNOLOGY AND BIOENGINEERING

Knocking down barriers: advances in siRNA delivery

(2009) Kathryn A. Whitehead et al.   NATURE REVIEWS DRUG DISCOVERY

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

In Situ Regulation of DC Subsets and T Cells Mediates Tumor Regression in Mice

(2009) O. A. Ali et al.   Science Translational Medicine

Light-Induced Temperature Transitions in Biodegradable Polymer and Nanorod Composites

(2009) Kolin C. Hribar et al.   Small

Sequential crosslinking to control cellular spreading in 3-dimensional hydrogels

(2009) Sudhir Khetan et al.   Soft Matter

Hydrolytically Degradable Hyaluronic Acid Hydrogels with Controlled Temporal Structures

(2008) Sujata Sahoo et al.   BIOMACROMOLECULES

Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: Systematic modulation of a synthetic cell-responsive PEG-hydrogel

(2008) Thomas P. Kraehenbuehl et al.   BIOMATERIALS

Three-dimensional micropatterning of bioactive hydrogels via two-photon laser scanning photolithography for guided 3D cell migration

(2008) Soo-Hong Lee et al.   BIOMATERIALS

Electrospinning: Applications in drug delivery and tissue engineering

(2008) Travis J. Sill et al.   BIOMATERIALS

Growth factor gradients via microsphere delivery in biopolymer scaffolds for osteochondral tissue engineering

(2008) Xiaoqin Wang et al.   JOURNAL OF CONTROLLED RELEASE

Nanoparticle therapeutics: an emerging treatment modality for cancer

(2008) Mark E. Davis et al.   NATURE REVIEWS DRUG DISCOVERY

Polymeric Biomaterials in Tissue Engineering

(2008) Daniel S Kohane et al.   PEDIATRIC RESEARCH

Foreign body reaction to biomaterials

(2008) James M. Anderson et al.   SEMINARS IN IMMUNOLOGY

Image-Guided Tissue Engineering of Anatomically Shaped Implants via MRI and Micro-CT Using Injection Molding

(2008) Jeffrey J. Ballyns et al.   TISSUE ENGINEERING PART A

Cell Encapsulation in Biodegradable Hydrogels for Tissue Engineering Applications

(2008) Garret D. Nicodemus et al.   TISSUE ENGINEERING PART B-REVIEWS