Mechanosignalling via integrins directs fate decisions of pancreatic progenitors

EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity

(2017) Zarah M. Löf-Öhlin et al.   NATURE CELL BIOLOGY

YAP/TAZ link cell mechanics to Notch signalling to control epidermal stem cell fate

(2017) Antonio Totaro et al.   Nature Communications

Efficient Generation of Glucose-Responsive Beta Cells from Isolated GP2 + Human Pancreatic Progenitors

(2017) Jacqueline Ameri et al.   Cell Reports

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4

(2015) Nina S. Funa et al.   Cell Stem Cell

TEAD and YAP regulate the enhancer network of human embryonic pancreatic progenitors

(2015) Inês Cebola et al.   NATURE CELL BIOLOGY

Developmental regulation of apical endocytosis controls epithelial patterning in vertebrate tubular organs

(2015) Alejo E. Rodríguez-Fraticelli et al.   NATURE CELL BIOLOGY

limma powers differential expression analyses for RNA-sequencing and microarray studies

(2015) Matthew E. Ritchie et al.   NUCLEIC ACIDS RESEARCH

Transcriptional Co-repressor Function of the Hippo Pathway Transducers YAP and TAZ

(2015) Minchul Kim et al.   Cell Reports

Hippo Pathway Effectors Control Cardiac Progenitor Cell Fate by Acting as Dynamic Sensors of Substrate Mechanics and Nanostructure

(2014) Diogo Mosqueira et al.   ACS Nano

Cdc42/N-WASP signaling links actin dynamics to pancreatic   cell delamination and differentiation

(2014) G. Kesavan et al.   DEVELOPMENT

Expression of type I collagen and tenascin C is regulated by actin polymerization through MRTF in dedifferentiated chondrocytes

(2014) Justin Parreno et al.   FEBS LETTERS

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

A method to recapitulate early embryonic spatial patterning in human embryonic stem cells

(2014) Aryeh Warmflash et al.   NATURE METHODS

Pancreas Organogenesis: From Lineage Determination to Morphogenesis

(2013) Hung Ping Shih et al.   Annual Review of Cell and Developmental Biology

Hippo Signaling Regulates Differentiation and Maintenance in the Exocrine Pancreas

(2013) Tao Gao et al.   GASTROENTEROLOGY

β1- and αv-class integrins cooperate to regulate myosin II during rigidity sensing of fibronectin-based microenvironments

(2013) Herbert B. Schiller et al.   NATURE CELL BIOLOGY

Enrichment of human embryonic stem cell-derived NKX6.1-expressing pancreatic progenitor cells accelerates the maturation of insulin-secreting cells in vivo

(2013) Alireza Rezania et al.   STEM CELLS

Switch Enhancers Interpret TGF-β and Hippo Signaling to Control Cell Fate in Human Embryonic Stem Cells

(2013) Tobias A. Beyer et al.   Cell Reports

Signaling crosstalk between TGFβ and Dishevelled/Par1b

(2012) A Mamidi et al.   CELL DEATH AND DIFFERENTIATION

Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice

(2012) A. Rezania et al.   DIABETES

Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP

(2012) Y. Liu-Chittenden et al.   GENES & DEVELOPMENT

Cell detachment activates the Hippo pathway via cytoskeleton reorganization to induce anoikis

(2012) B. Zhao et al.   GENES & DEVELOPMENT

Hippo Signaling Regulates Pancreas Development through Inactivation of Yap

(2012) N. M. George et al.   MOLECULAR AND CELLULAR BIOLOGY

Mind bomb 1 is required for pancreatic  -cell formation

(2012) S. Horn et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Sox9+ ductal cells are multipotent progenitors throughout development but do not produce new endocrine cells in the normal or injured adult pancreas

(2011) J. L. Kopp et al.   DEVELOPMENT

Pancreas organogenesis: From bud to plexus to gland

(2011) Fong Cheng Pan et al.   DEVELOPMENTAL DYNAMICS

A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos

(2011) Rasmus Klinck et al.   GENE EXPRESSION PATTERNS

Inhibitors of Src and Focal Adhesion Kinase Promote Endocrine Specification

(2011) Ivka Afrikanova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of YAP/TAZ in mechanotransduction

(2011) Sirio Dupont et al.   NATURE

The Merlin/NF2 Tumor Suppressor Functions through the YAP Oncoprotein to Regulate Tissue Homeostasis in Mammals

(2010) Nailing Zhang et al.   DEVELOPMENTAL CELL

Geometric cues for directing the differentiation of mesenchymal stem cells

(2010) K. A. Kilian et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

FAM/USP9x, a Deubiquitinating Enzyme Essential for TGFβ Signaling, Controls Smad4 Monoubiquitination

(2009) Sirio Dupont et al.   CELL

Cdc42-Mediated Tubulogenesis Controls Cell Specification

(2009) Gokul Kesavan et al.   CELL

Adhesion signaling - crosstalk between integrins, Src and Rho

(2009) S. Huveneers et al.   JOURNAL OF CELL SCIENCE