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Title
Advances in islet encapsulation technologies
Authors
Keywords
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Journal
NATURE REVIEWS DRUG DISCOVERY
Volume 16, Issue 5, Pages 338-350
Publisher
Springer Nature
Online
2016-12-25
DOI
10.1038/nrd.2016.232
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- (2016) Xunrong Luo et al. Annual Review of Biomedical Engineering
- Spatially localized recruitment of anti-inflammatory monocytes by SDF-1α-releasing hydrogels enhances microvascular network remodeling
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- (2016) Chaiyaboot Ariyachet et al. Cell Stem Cell
- Optimization and Scale-up Isolation and Culture of Neonatal Porcine Islets: Potential for Clinical Application
- (2016) Cara Ellis et al. CELL TRANSPLANTATION
- Bioengineering the Endocrine Pancreas: Intraomental Islet Transplantation Within a Biologic Resorbable Scaffold
- (2016) Dora M. Berman et al. DIABETES
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- (2016) Bernhard J. Hering et al. DIABETES CARE
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- (2016) Arturo J Vegas et al. NATURE BIOTECHNOLOGY
- Long-term glycemic control using polymer-encapsulated human stem cell–derived beta cells in immune-competent mice
- (2016) Arturo J Vegas et al. NATURE MEDICINE
- Tunable Microfibers Suppress Fibrotic Encapsulation via Inhibition of TGFβ Signaling
- (2016) Jessica Allen et al. TISSUE ENGINEERING PART A
- First update of the International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-Chapter 2b: genetically modified source pigs
- (2016) Peter J. Cowan et al. XENOTRANSPLANTATION
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- (2015) Crystal E. Nyitray et al. ACS Nano
- Stratifying Patients Based on Epitope Mismatching: Ready for Primetime?
- (2015) D. Glotz et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Long-Term Control of Diabetes in Immunosuppressed Nonhuman Primates (NHP) by the Transplantation of Adult Porcine Islets
- (2015) J. S. Shin et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Alginate Encapsulant Incorporating CXCL12 Supports Long-Term Allo- and Xenoislet Transplantation Without Systemic Immune Suppression
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- (2015) Omid Veiseh et al. NATURE MATERIALS
- Type 1 diabetes immunotherapy using polyclonal regulatory T cells
- (2015) Jeffrey A. Bluestone et al. Science Translational Medicine
- Diabetes Is Reversed in a Murine Model by Marginal Mass Syngeneic Islet Transplantation Using a Subcutaneous Cell Pouch Device
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- Regulatory T Cells: Serious Contenders in the Promise for Immunological Tolerance in Transplantation
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- Control of IBMIR in Neonatal Porcine Islet Xenotransplantation in Baboons
- (2014) W. J. Hawthorne et al. AMERICAN JOURNAL OF TRANSPLANTATION
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- (2014) R. Bottino et al. AMERICAN JOURNAL OF TRANSPLANTATION
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- (2014) Brian J. Kwee et al. ANNALS OF BIOMEDICAL ENGINEERING
- Bioengineering the Ovarian Follicle Microenvironment
- (2014) Lonnie D. Shea et al. Annual Review of Biomedical Engineering
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- (2014) Alireza Rezania et al. NATURE BIOTECHNOLOGY
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- (2014) A. A. Tomei et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2014) Christophe Willems et al. Regenerative Medicine
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- (2013) Omaima M. Sabek et al. LAB ON A CHIP
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- (2013) Tova Neufeld et al. PLoS One
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- (2013) B. Ludwig et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
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- (2013) John G. Graham et al. TISSUE ENGINEERING PART A
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- (2013) Patricia Luz-Crawford et al. Stem Cell Research & Therapy
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- (2013) Edward A. Phelps et al. Drug Delivery and Translational Research
- Mechanisms Underlying CD4+ Treg Immune Regulation in the Adult: From Experiments to Models
- (2013) Marta Caridade et al. Frontiers in Immunology
- A Novel Monoclonal Antibody to CD40 Prolongs Islet Allograft Survival
- (2012) M. Lowe et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Alternative Immunomodulatory Strategies for Xenotransplantation: CD40/154 Pathway-Sparing Regimens Promote Xenograft Survival
- (2012) P. Thompson et al. AMERICAN JOURNAL OF TRANSPLANTATION
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- (2012) G. Chen et al. AMERICAN JOURNAL OF TRANSPLANTATION
- Regulatory T-cell therapy for transplantation
- (2012) Qizhi Tang et al. Current Opinion in Organ Transplantation
- Maturation of Human Embryonic Stem Cell-Derived Pancreatic Progenitors Into Functional Islets Capable of Treating Pre-existing Diabetes in Mice
- (2012) A. Rezania et al. DIABETES
- Improvement in Outcomes of Clinical Islet Transplantation: 1999-2010
- (2012) F. B. Barton et al. DIABETES CARE
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- (2012) Jamil Stanekzai et al. DIABETES RESEARCH AND CLINICAL PRACTICE
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- (2012) Karen English IMMUNOLOGY AND CELL BIOLOGY
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- (2012) E. Pedraza et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Antidiabetic Effect of Mesenchymal Stem Cells Is Unrelated to Their Transdifferentiation Potential But to Their Capability to Restore Th1/Th2 Balance and to Modify the Pancreatic Microenvironment
- (2012) Fernando Ezquer et al. STEM CELLS
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- (2012) Virginie Bonnamain et al. STEM CELLS
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- (2011) Soyoung Lee et al. Acta Biomaterialia
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- (2011) Anne Mari Rokstad et al. Acta Biomaterialia
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- (2011) P. Thompson et al. AMERICAN JOURNAL OF TRANSPLANTATION
- CD40-Specific Costimulation Blockade Enhances Neonatal Porcine Islet Survival in Nonhuman Primates
- (2011) P. Thompson et al. AMERICAN JOURNAL OF TRANSPLANTATION
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- (2011) Natalia Marek et al. ANNALS OF SURGERY
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- (2011) Enrica Saino et al. BIOMACROMOLECULES
- Ex vivo expansion of human Tregs specific for alloantigens presented directly or indirectly
- (2011) A. Veerapathran et al. BLOOD
- Long-Term Metabolic and Immunological Follow-Up of Nonimmunosuppressed Patients With Type 1 Diabetes Treated With Microencapsulated Islet Allografts: Four cases
- (2011) G. Basta et al. DIABETES CARE
- Advancing islet transplantation: from engraftment to the immune response
- (2011) R. F. Gibly et al. DIABETOLOGIA
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- (2011) Yoshifumi Sato et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2011) E. S. Yolcu et al. JOURNAL OF IMMUNOLOGY
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- (2010) Jiashing Yu et al. BIOMATERIALS
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- (2010) L. Sanchez-Martin et al. BLOOD
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- (2010) Nathan Karin JOURNAL OF LEUKOCYTE BIOLOGY
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- (2009) D. J. van der Windt et al. AMERICAN JOURNAL OF TRANSPLANTATION
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