Synthetic matrices reveal contributions of ECM biophysical and biochemical properties to epithelial morphogenesis

Basal localization of MT1-MMP is essential for epithelial cell morphogenesis in 3D collagen matrix

(2014) S. A. Weaver et al.   JOURNAL OF CELL SCIENCE

The influence of matrix properties on growth and morphogenesis of human pancreatic ductal epithelial cells in 3D

(2013) Asad Raza et al.   BIOMATERIALS

The independent roles of mechanical, structural and adhesion characteristics of 3D hydrogels on the regulation of cancer invasion and dissemination

(2013) Jennifer N. Beck et al.   BIOMATERIALS

Vasculogenic bio-synthetic hydrogel for enhancement of pancreatic islet engraftment and function in type 1 diabetes

(2013) Edward A. Phelps et al.   BIOMATERIALS

Degradation-mediated cellular traction directs stem cell fate in covalently crosslinked three-dimensional hydrogels

(2013) Sudhir Khetan et al.   NATURE MATERIALS

αV-Integrins Are Required for Mechanotransduction in MDCK Epithelial Cells

(2013) Terhi P. Teräväinen et al.   PLoS One

Polarity in Mammalian Epithelial Morphogenesis

(2013) J. Roignot et al.   Cold Spring Harbor Perspectives in Biology

The impact of adhesion peptides within hydrogels on the phenotype and signaling of normal and cancerous mammary epithelial cells

(2012) Michael S. Weiss et al.   BIOMATERIALS

A Synthetic Matrix with Independently Tunable Biochemistry and Mechanical Properties to Study Epithelial Morphogenesis and EMT in a Lung Adenocarcinoma Model

(2012) B. J. Gill et al.   CANCER RESEARCH

Dual Delivery of Hepatocyte and Vascular Endothelial Growth Factors via a Protease-Degradable Hydrogel Improves Cardiac Function in Rats

(2012) Apoorva S. Salimath et al.   PLoS One

Maleimide Cross-Linked Bioactive PEG Hydrogel Exhibits Improved Reaction Kinetics and Cross-Linking for Cell Encapsulation and In Situ Delivery

(2011) Edward A. Phelps et al.   ADVANCED MATERIALS

A tension-induced mechanotransduction pathway promotes epithelial morphogenesis

(2011) Huimin Zhang et al.   NATURE

Enhanced proteolytic degradation of molecularly engineered PEG hydrogels in response to MMP-1 and MMP-2

(2010) J. Patterson et al.   BIOMATERIALS

Harnessing traction-mediated manipulation of the cell/matrix interface to control stem-cell fate

(2010) Nathaniel Huebsch et al.   NATURE MATERIALS

Matrigel: A complex protein mixture required for optimal growth of cell culture

(2010) Chris S. Hughes et al.   PROTEOMICS

Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling

(2009) Kandice R. Levental et al.   CELL

 1 integrin is necessary for ureteric bud branching morphogenesis and maintenance of collecting duct structural integrity

(2009) X. Zhang et al.   DEVELOPMENT

Matrix density-induced mechanoregulation of breast cell phenotype, signaling and gene expression through a FAK–ERK linkage

(2009) P P Provenzano et al.   ONCOGENE

Controlled release of functional proteins through designer self-assembling peptide nanofiber hydrogel scaffold

(2009) S. Koutsopoulos et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Photodegradable Hydrogels for Dynamic Tuning of Physical and Chemical Properties

(2009) April M. Kloxin et al.   SCIENCE

Cell-Polarity Dynamics Controls the Mechanism of Lumen Formation in Epithelial Morphogenesis

(2008) Fernando Martín-Belmonte et al.   CURRENT BIOLOGY

From cells to organs: building polarized tissue

(2008) David M. Bryant et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The Effect of Matrix Density on the Regulation of 3-D Capillary Morphogenesis

(2007) Cyrus M. Ghajar et al.   BIOPHYSICAL JOURNAL