Proteasomes and Several Aspects of Their Heterogeneity Relevant to Cancer
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Title
Proteasomes and Several Aspects of Their Heterogeneity Relevant to Cancer
Authors
Keywords
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Journal
Frontiers in Oncology
Volume 9, Issue -, Pages -
Publisher
Frontiers Media SA
Online
2019-08-13
DOI
10.3389/fonc.2019.00761
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Note: Only part of the references are listed.- The coordinated action of VCP/p97 and GCN2 regulates cancer cell metabolism and proteostasis during nutrient limitation
- (2019) Katarzyna Parzych et al. ONCOGENE
- Small Molecule Modulation of Proteasome Assembly
- (2018) Evert Njomen et al. BIOCHEMISTRY
- MAGE-A antigens as targets for cancer immunotherapy
- (2018) Erik Schooten et al. CANCER TREATMENT REVIEWS
- Functional regulation of proteins by 20S proteasome proteolytic processing
- (2018) Maya A. Olshina et al. CELL CYCLE
- VCP/p97/Cdc48, A Linking of Protein Homeostasis and Cancer Therapy
- (2018) B. Lan et al. CURRENT MOLECULAR MEDICINE
- Thermal proteome profiling of breast cancer cells reveals proteasomal activation by CDK4/6 inhibitor palbociclib
- (2018) Teemu P Miettinen et al. EMBO JOURNAL
- Spectrum and functional validation of PSMB5 mutations in multiple myeloma
- (2018) Santiago Barrio et al. LEUKEMIA
- Targeting the Proteasome-Associated Deubiquitinating Enzyme USP14 Impairs Melanoma Cell Survival and Overcomes Resistance to MAPK-Targeting Therapies
- (2018) Robin Didier et al. MOLECULAR CANCER THERAPEUTICS
- Growth arrest and apoptosis induction in androgen receptor-positive human breast cancer cells by inhibition of USP14-mediated androgen receptor deubiquitination
- (2018) Yuning Liao et al. ONCOGENE
- Massive expression of germ cell-specific genes is a hallmark of cancer and a potential target for novel treatment development
- (2018) Jan Willem Bruggeman et al. ONCOGENE
- Immunoproteasome-selective and non-selective inhibitors: A promising approach for the treatment of multiple myeloma
- (2018) Roberta Ettari et al. PHARMACOLOGY & THERAPEUTICS
- Next-generation proteasome inhibitors for cancer therapy
- (2018) Ji Eun Park et al. Translational Research
- Oncogenic addiction to high 26S proteasome level
- (2018) Peter Tsvetkov et al. Cell Death & Disease
- Expression of Immunoproteasome Subunit LMP7 in Breast Cancer and Its Association with Immune-Related Markers
- (2018) Miseon Lee et al. Cancer Research and Treatment
- DNA damage‐induced replication stress results in PA200‐proteasome‐mediated degradation of acetylated histones
- (2018) Imke K Mandemaker et al. EMBO REPORTS
- USP14 as a novel prognostic marker promotes cisplatin resistance via Akt/ERK signaling pathways in gastric cancer
- (2018) Ying Fu et al. Cancer Medicine
- Combined Effect of Bortezomib and Menadione Sodium Bisulfite on Proteasomes of Tumor Cells: The Dramatic Decrease of Bortezomib Toxicity in a Preclinical Trial
- (2018) Tatiana Astakhova et al. Cancers
- Structural Basis of p97 Inhibition by the Site-Selective Anti-Cancer Compound CB-5083
- (2018) Wai Kwan Tang et al. MOLECULAR PHARMACOLOGY
- REGγ accelerates melanoma formation by regulating Wnt/β-catenin signalling pathway
- (2017) Hui Chen et al. EXPERIMENTAL DERMATOLOGY
- Proteasome 26S subunit PSMD1 regulates breast cancer cell growth through p53 protein degradation
- (2017) Toshiyuki Okumura et al. JOURNAL OF BIOCHEMISTRY
- Proteasome inhibitors in cancer therapy
- (2017) Elisabet E. Manasanch et al. Nature Reviews Clinical Oncology
- A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function
- (2017) Kapil V Ramachandran et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Ubiquitinated proteins promote the association of proteasomes with the deubiquitinating enzyme Usp14 and the ubiquitin ligase Ube3c
- (2017) Chueh-Ling Kuo et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Ubiquitin- and ATP-dependent unfoldase activity of P97/VCP•NPLOC4•UFD1L is enhanced by a mutation that causes multisystem proteinopathy
- (2017) Emily E. Blythe et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structural insights into the functional cycle of the ATPase module of the 26S proteasome
- (2017) Marc Wehmer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The Mammalian Proteasome Activator PA28 Forms an Asymmetric α 4 β 3 Complex
- (2017) Eva M. Huber et al. STRUCTURE
- Proteasome expression and activity in cancer and cancer stem cells
- (2017) Ioannis A Voutsadakis TUMOR BIOLOGY
- Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus
- (2017) Muhammad Myn Uddin et al. Nature Communications
- A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function
- (2017) Kapil V Ramachandran et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Detection of active proteasome structures in brain extracts: proteasome features of August rat brain with violations in monoamine metabolism
- (2017) Pavel A. Erokhov et al. Oncotarget
- miR-195-5p is critical in REGγ-mediated regulation of wnt/β-catenin pathway in renal cell carcinoma
- (2017) Shaojun Chen et al. Oncotarget
- Prevention of colitis-associated cancer by selective targeting of immunoproteasome subunit LMP7
- (2017) Niyati Vachharajani et al. Oncotarget
- Immunoproteasome functions explained by divergence in cleavage specificity and regulation
- (2017) Michael B Winter et al. eLife
- PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection
- (2017) Dorota Respondek et al. PLoS One
- Crystal structure of a low molecular weight activator Blm-pep with yeast 20S proteasome – insights into the enzyme activation mechanism
- (2017) Julia Witkowska et al. Scientific Reports
- Mammalian proteasome subtypes: Their diversity in structure and function
- (2016) Burkhardt Dahlmann ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- The life cycle of the 26S proteasome: from birth, through regulation and function and onto its death
- (2016) Ido Livneh et al. CELL RESEARCH
- Function of Deubiquitinating Enzyme USP14 as Oncogene in Different Types of Cancer
- (2016) Ying Zhu et al. CELLULAR PHYSIOLOGY AND BIOCHEMISTRY
- Strategic role of the ubiquitin-dependent segregase p97 (VCP or Cdc48) in DNA replication
- (2016) Kristijan Ramadan et al. CHROMOSOMA
- Inhibition of Proteasome Activity Induces Formation of Alternative Proteasome Complexes
- (2016) Vanessa Welk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Overexpression of proteasomal activator PA28α serves as a prognostic factor in oral squamous cell carcinoma
- (2016) Xiaodong Feng et al. JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH
- Biological significance of co- and post-translational modifications of the yeast 26S proteasome
- (2016) Hisashi Hirano et al. Journal of Proteomics
- Degradation of oxidized proteins by the proteasome: Distinguishing between the 20S, 26S, and immunoproteasome proteolytic pathways
- (2016) Rachel Raynes et al. MOLECULAR ASPECTS OF MEDICINE
- An atomic structure of the human 26S proteasome
- (2016) Xiuliang Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Immunoproteasome deficiency is a feature of non-small cell lung cancer with a mesenchymal phenotype and is associated with a poor outcome
- (2016) Satyendra C. Tripathi et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of an endogenous yeast 26S proteasome reveals two major conformational states
- (2016) Bai Luan et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Suppression of 19S proteasome subunits marks emergence of an altered cell state in diverse cancers
- (2016) Peter Tsvetkov et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the human 26S proteasome at a resolution of 3.9 Å
- (2016) Andreas Schweitzer et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The REGγ-proteasome forms a regulatory circuit with IκBɛ and NFκB in experimental colitis
- (2016) Jinjin Xu et al. Nature Communications
- Regulation of energy homeostasis by the ubiquitin-independent REGγ proteasome
- (2016) Lianhui Sun et al. Nature Communications
- An atomic structure of the human 26S proteasome
- (2016) Xiuliang Huang et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Downregulation of 26S proteasome catalytic activity promotes epithelial-mesenchymal transition
- (2016) Asoka Banno et al. Oncotarget
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- (2016) Rachel Isaksson Vogel et al. Oncotarget
- microRNA Therapeutics in Cancer — An Emerging Concept
- (2016) Maitri Y. Shah et al. EBioMedicine
- Targeting p97 to Disrupt Protein Homeostasis in Cancer
- (2016) Pratikkumar Harsukhbhai Vekaria et al. Frontiers in Oncology
- Expression of immunoproteasome genes is regulated by cell-intrinsic and –extrinsic factors in human cancers
- (2016) Alexandre Rouette et al. Scientific Reports
- REGγ regulates ERα degradation via ubiquitin–proteasome pathway in breast cancer
- (2015) Fan Chai et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- VCP and PSMF1: Antagonistic regulators of proteasome activity
- (2015) Christoph S. Clemen et al. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS
- Targeting the AAA ATPase p97 as an Approach to Treat Cancer through Disruption of Protein Homeostasis
- (2015) Daniel J. Anderson et al. CANCER CELL
- Mutant p53 (p53-R248Q) functions as an oncogene in promoting endometrial cancer by up-regulating REGγ
- (2015) Huihui Wang et al. CANCER LETTERS
- miR-7-5p suppresses cell proliferation and induces apoptosis of breast cancer cells mainly by targeting REGγ
- (2015) Yuan Shi et al. CANCER LETTERS
- Immunoproteasomes edit tumors, which then escapes immune recognition
- (2015) Sebastian Joyce EUROPEAN JOURNAL OF IMMUNOLOGY
- The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognition
- (2015) Martin Keller et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- Deciphering preferential interactions within supramolecular protein complexes: the proteasome case
- (2015) B. Fabre et al. Molecular Systems Biology
- Inhibitors of the AAA+ Chaperone p97
- (2015) Eli Chapman et al. MOLECULES
- Site-specific proteasome phosphorylation controls cell proliferation and tumorigenesis
- (2015) Xing Guo et al. NATURE CELL BIOLOGY
- TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8+ T cells
- (2015) Kensuke Takada et al. NATURE IMMUNOLOGY
- Exogenous Hsp70 delays senescence and improves cognitive function in aging mice
- (2015) Natalia V. Bobkova et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- High expression of valosin-containing protein predicts poor prognosis in patients with breast carcinoma
- (2015) Yan Cui et al. TUMOR BIOLOGY
- Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells
- (2015) Katsuhiro Sasaki et al. Nature Communications
- REGγ is critical for skin carcinogenesis by modulating the Wnt/β-catenin pathway
- (2015) Lei Li et al. Nature Communications
- Quantitative time-resolved analysis reveals intricate, differential regulation of standard- and immuno-proteasomes
- (2015) Juliane Liepe et al. eLife
- The immunoproteasome and viral infection: a complex regulator of inflammation
- (2015) Mary K. McCarthy et al. Frontiers in Microbiology
- Tumor cells with low proteasome subunit expression predict overall survival in head and neck cancer patients
- (2014) Chann Lagadec et al. BMC CANCER
- Regulation of c-Myc protein stability by proteasome activator REGγ
- (2014) S Li et al. CELL DEATH AND DIFFERENTIATION
- PA28αβ Reduces Size and Increases Hydrophilicity of 20S Immunoproteasome Peptide Products
- (2014) Mary Raule et al. CHEMISTRY & BIOLOGY
- Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation
- (2014) Michele Mishto et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- The central domain of yeast transcription factor Rpn4 facilitates degradation of reporter protein in human cells
- (2014) A.V. Morozov et al. FEBS LETTERS
- Characterization of the Testis-specific Proteasome Subunit α4s in Mammals
- (2014) Hiroyuki Uechi et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Molecular and Cellular Roles of PI31 (PSMF1) Protein in Regulation of Proteasome Function
- (2014) Xiaohua Li et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- The VCP/p97 system at a glance: connecting cellular function to disease pathogenesis
- (2014) H. Meyer et al. JOURNAL OF CELL SCIENCE
- The requirement for Cdc48/p97 in nuclear protein quality control degradation depends on the substrate and correlates with substrate insolubility
- (2014) P. S. Gallagher et al. JOURNAL OF CELL SCIENCE
- Allele-Selective Effect of PA28 in MHC Class I Antigen Processing
- (2014) T. Yamano et al. JOURNAL OF IMMUNOLOGY
- Immunoproteasomes Shape the Transcriptome and Regulate the Function of Dendritic Cells
- (2014) D. A. de Verteuil et al. JOURNAL OF IMMUNOLOGY
- PKA turnover by the REGγ-proteasome modulates FoxO1 cellular activity and VEGF-induced angiogenesis
- (2014) Shuang Liu et al. JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY
- Label-Free Quantitative Proteomics Reveals the Dynamics of Proteasome Complexes Composition and Stoichiometry in a Wide Range of Human Cell Lines
- (2014) Bertrand Fabre et al. JOURNAL OF PROTEOME RESEARCH
- Structure of the Rpn11–Rpn8 dimer reveals mechanisms of substrate deubiquitination during proteasomal degradation
- (2014) Evan J Worden et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Deep classification of a large cryo-EM dataset defines the conformational landscape of the 26S proteasome
- (2014) P. Unverdorben et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Architecture and assembly of the archaeal Cdc48*20S proteasome
- (2014) D. Barthelme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The proteasome and the degradation of oxidized proteins: Part III—Redox regulation of the proteasomal system
- (2014) Tobias Jung et al. Redox Biology
- Thymoproteasome: Role in Thymic Selection and Clinical Significance as a Diagnostic Marker for Thymic Epithelial Tumors
- (2013) Utano Tomaru et al. ARCHIVUM IMMUNOLOGIAE ET THERAPIAE EXPERIMENTALIS
- Regulation of proteasome activity in health and disease
- (2013) Marion Schmidt et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Ubiquitin-independent proteasomal degradation
- (2013) Jenny Erales et al. BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH
- Reactive glia show increased immunoproteasome activity in Alzheimer’s disease
- (2013) Marie Orre et al. BRAIN
- PA28gamma emerges as a novel functional target of tumour suppressor microRNA-7 in non-small-cell lung cancer
- (2013) S Xiong et al. BRITISH JOURNAL OF CANCER
- P97/CDC-48: Proteostasis control in tumor cell biology
- (2013) Delphine Fessart et al. CANCER LETTERS
- Proteasome Regulation by ADP-Ribosylation
- (2013) Park F. Cho-Park et al. CELL
- Immuno- and Constitutive Proteasomes Do Not Differ in Their Abilities to Degrade Ubiquitinated Proteins
- (2013) James A. Nathan et al. CELL
- Acetylation-Mediated Proteasomal Degradation of Core Histones during DNA Repair and Spermatogenesis
- (2013) Min-Xian Qian et al. CELL
- Immunoproteasomes Are Important for Proteostasis in Immune Responses
- (2013) Frédéric Ebstein et al. CELL
- The REGγ Proteasome Regulates Hepatic Lipid Metabolism through Inhibition of Autophagy
- (2013) Shuxian Dong et al. Cell Metabolism
- T lymphocytes export proteasomes by way of microparticles: a possible mechanism for generation of extracellular proteasomes
- (2013) Isabel Bochmann et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Melanoma immunotherapy using mature DCs expressing the constitutive proteasome
- (2013) Jens Dannull et al. JOURNAL OF CLINICAL INVESTIGATION
- Expression of thymoproteasome subunit β5t in type AB thymoma
- (2013) Yosuke Yamada et al. JOURNAL OF CLINICAL PATHOLOGY
- Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses
- (2013) D. Zanker et al. JOURNAL OF IMMUNOLOGY
- The Rhesus Macaque (Macaca mulatta) Sperm Proteome
- (2013) Sheri Skerget et al. MOLECULAR & CELLULAR PROTEOMICS
- Identification of the Immunoproteasome as a Novel Regulator of Skeletal Muscle Differentiation
- (2013) Z. Cui et al. MOLECULAR AND CELLULAR BIOLOGY
- Reconstitution of the 26S proteasome reveals functional asymmetries in its AAA+ unfoldase
- (2013) Robyn Beckwith et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Conformational switching of the 26S proteasome enables substrate degradation
- (2013) Mary E Matyskiela et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Reduction in ATP Levels Triggers Immunoproteasome Activation by the 11S (PA28) Regulator during Early Antiviral Response Mediated by IFNβ in Mouse Pancreatic β-Cells
- (2013) Wieke Freudenburg et al. PLoS One
- Bipartite determinants mediate an evolutionarily conserved interaction between Cdc48 and the 20Speptidase
- (2013) Dominik Barthelme et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Thymoproteasome subunit- 5T generates peptide-MHC complexes specialized for positive selection
- (2013) Y. Xing et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Proteasome activator complex PA28 identified as an accessible target in prostate cancer by in vivo selection of human antibodies
- (2013) David Sánchez-Martín et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- REG deficiency promotes premature aging via the casein kinase 1 pathway
- (2013) L. Li et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Structure of the 26S proteasome with ATP- S bound provides insights into the mechanism of nucleotide-dependent substrate translocation
- (2013) P. Sledz et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Functions of the 19S complex in proteasomal degradation
- (2013) Chang-Wei Liu et al. TRENDS IN BIOCHEMICAL SCIENCES
- The unique functions of tissue-specific proteasomes
- (2013) Andrea Kniepert et al. TRENDS IN BIOCHEMICAL SCIENCES
- Differential regulation of the REGγ–proteasome pathway by p53/TGF-β signalling and mutant p53 in cancer cells
- (2013) Amjad Ali et al. Nature Communications
- Differential roles of proteasome and immunoproteasome regulators Pa28αβ, Pa28γ and Pa200 in the degradation of oxidized proteins
- (2012) Andrew M. Pickering et al. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS
- Expression of Proteasome Activator REGγ in Human Laryngeal Carcinoma and Associations with Tumor Suppressor Proteins
- (2012) Li-Ping Li et al. Asian Pacific Journal of Cancer Prevention
- Advanced-glycation-end-product-induced formation of immunoproteasomes: involvement of RAGE and Jak2/STAT1
- (2012) Stefanie Grimm et al. BIOCHEMICAL JOURNAL
- REGγ is associated with multiple oncogenic pathways in human cancers
- (2012) Jing He et al. BMC CANCER
- A selective inhibitor of the immunoproteasome subunit LMP2 induces apoptosis in PC-3 cells and suppresses tumour growth in nude mice
- (2012) M Wehenkel et al. BRITISH JOURNAL OF CANCER
- Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity
- (2012) Eva M. Huber et al. CELL
- Rpn1 and Rpn2 Coordinate Ubiquitin Processing Factors at Proteasome
- (2012) Rina Rosenzweig et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Proteasome subunit β5t expression in cervical ectopic thymoma
- (2012) Utano Tomaru et al. JOURNAL OF CLINICAL PATHOLOGY
- Analysis of the Processing of Seven Human Tumor Antigens by Intermediate Proteasomes
- (2012) B. Guillaume et al. JOURNAL OF IMMUNOLOGY
- Molecular Mechanisms of Acquired Proteasome Inhibitor Resistance
- (2012) Andrew J. Kale et al. JOURNAL OF MEDICINAL CHEMISTRY
- Distinct Proteasome Subpopulations in the Alveolar Space of Patients with the Acute Respiratory Distress Syndrome
- (2012) S. U. Sixt et al. MEDIATORS OF INFLAMMATION
- DNA vaccine encoding α-fetoprotein fused with the ornithine decarboxylase degradation signal significantly suppresses the hepatocellular carcinoma growth in mice
- (2012) A. V. Morozov et al. MOLECULAR BIOLOGY
- The Proteasome Activator PA200 Regulates Tumor Cell Responsiveness to Glutamine and Resistance to Ionizing Radiation
- (2012) J. Blickwedehl et al. MOLECULAR CANCER RESEARCH
- Molecular Model of the Human 26S Proteasome
- (2012) Paula C.A. da Fonseca et al. MOLECULAR CELL
- The Proteasome System in Infection: Impact of β5 and LMP7 on Composition, Maturation and Quantity of Active Proteasome Complexes
- (2012) Thorsten Joeris et al. PLoS One
- Identification of the Cdc48bullet20S Proteasome as an Ancient AAA+ Proteolytic Machine
- (2012) D. Barthelme et al. SCIENCE
- Bortezomib Combination Therapy in Multiple Myeloma
- (2012) Prashant Kapoor et al. SEMINARS IN HEMATOLOGY
- A Putative Role for the Immunoproteasome in the Maintenance of Pluripotency in Human Embryonic Stem Cells
- (2012) Stuart P. Atkinson et al. STEM CELLS
- Expression of Proteasome Subunit β5t in Thymic Epithelial Tumors
- (2011) Yosuke Yamada et al. AMERICAN JOURNAL OF SURGICAL PATHOLOGY
- A Conserved F Box Regulatory Complex Controls Proteasome Activity in Drosophila
- (2011) Maya Bader et al. CELL
- LPS-Induced Formation of Immunoproteasomes: TNF-α and Nitric Oxide Production are Regulated by Altered Composition of Proteasome-Active Sites
- (2011) Julia Reis et al. CELL BIOCHEMISTRY AND BIOPHYSICS
- PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo
- (2011) Natascha de Graaf et al. EUROPEAN JOURNAL OF IMMUNOLOGY
- PA28β regulates cell invasion of gastric cancer via modulating the expression of chloride intracellular channel 1
- (2011) Da-Li Zheng et al. JOURNAL OF CELLULAR BIOCHEMISTRY
- REG-γ associates with and modulates the abundance of nuclear activation-induced deaminase
- (2011) Yasuhiro Uchimura et al. JOURNAL OF EXPERIMENTAL MEDICINE
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- (2011) Kenichi Kanai et al. JOURNAL OF MOLECULAR ENDOCRINOLOGY
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- (2011) Anca F. Savulescu et al. MOLECULAR & CELLULAR PROTEOMICS
- Mice completely lacking immunoproteasomes show major changes in antigen presentation
- (2011) Eleanor Z Kincaid et al. NATURE IMMUNOLOGY
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- (2011) Klara Acs et al. NATURE STRUCTURAL & MOLECULAR BIOLOGY
- Critical Role of VCP/p97 in the Pathogenesis and Progression of Non-Small Cell Lung Carcinoma
- (2011) Christopher W. Valle et al. PLoS One
- Radioresistance of prostate cancer cells with low proteasome activity
- (2011) Lorenza Della Donna et al. PROSTATE
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- (2010) Emilie Tresse et al. Autophagy
- The immunoproteasome, the 20S proteasome and the PA28αβ proteasome regulator are oxidative-stress-adaptive proteolytic complexes
- (2010) Andrew M. Pickering et al. BIOCHEMICAL JOURNAL
- Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress
- (2010) Ulrike Seifert et al. CELL
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- (2010) Alexandre Dalet et al. EUROPEAN JOURNAL OF IMMUNOLOGY
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- (2010) Jie Li et al. FASEB JOURNAL
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- (2010) Takeshi Nitta et al. IMMUNITY
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- (2010) Brajesh Kumar et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2010) Qiaojia Huang et al. JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY
- Reduced Immunoproteasome Formation and Accumulation of Immunoproteasomal Precursors in the Brains of Lymphocytic Choriomeningitis Virus-Infected Mice
- (2010) M. Kremer et al. JOURNAL OF IMMUNOLOGY
- REG gamma: a potential marker in breast cancer and effect on cell cycle and proliferation of breast cancer cell
- (2010) Xiaoyi Wang et al. MEDICAL ONCOLOGY
- Quantifying cross-tissue diversity in proteasome complexes by mass spectrometry
- (2010) Sarah Pelletier et al. Molecular BioSystems
- ATP-Dependent Steps in the Binding of Ubiquitin Conjugates to the 26S Proteasome that Commit to Degradation
- (2010) Andreas Peth et al. MOLECULAR CELL
- Structure of a Blm10 Complex Reveals Common Mechanisms for Proteasome Binding and Gate Opening
- (2010) Kianoush Sadre-Bazzaz et al. MOLECULAR CELL
- Structure of Proteasome Ubiquitin Receptor hRpn13 and Its Activation by the Scaffolding Protein hRpn2
- (2010) Xiang Chen et al. MOLECULAR CELL
- Enhancement of proteasome activity by a small-molecule inhibitor of USP14
- (2010) Byung-Hoon Lee et al. NATURE
- Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules
- (2010) B. Guillaume et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Characterization of the brain 26S proteasome and its interacting proteins
- (2010) Hwan-Ching Tai Frontiers in Molecular Neuroscience
- Recognition and Processing of Ubiquitin-Protein Conjugates by the Proteasome
- (2009) Daniel Finley Annual Review of Biochemistry
- Isolation of Mammalian 26S Proteasomes and p97/VCP Complexes Using the Ubiquitin-like Domain from HHR23B Reveals Novel Proteasome-Associated Proteins†
- (2009) Henrike C. Besche et al. BIOCHEMISTRY
- Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination
- (2009) James M. Baugh et al. JOURNAL OF MOLECULAR BIOLOGY
- The Proteasome-Associated Deubiquitinating Enzyme Usp14 Is Essential for the Maintenance of Synaptic Ubiquitin Levels and the Development of Neuromuscular Junctions
- (2009) P.-C. Chen et al. JOURNAL OF NEUROSCIENCE
- In Vivo Imaging, Tracking, and Targeting of Cancer Stem Cells
- (2009) Erina Vlashi et al. JNCI-Journal of the National Cancer Institute
- A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis
- (2009) Tony Muchamuel et al. NATURE MEDICINE
- The proteasome: Overview of structure and functions
- (2009) Keiji TANAKA PROCEEDINGS OF THE JAPAN ACADEMY SERIES B-PHYSICAL AND BIOLOGICAL SCIENCES
- Insights into the molecular architecture of the 26S proteasome
- (2009) S. Nickell et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- The proteasome 11S regulator subunit REGα (PA28α) is a heptamer
- (2009) Steven C. Johnston et al. PROTEIN SCIENCE
- Characterization of molecular markers indicative of cervical cancer progression
- (2009) Hilal Arnouk et al. Proteomics Clinical Applications
- A Tetrahedral Transition State at the Active Sites of the 20S Proteasome Is Coupled to Opening of the α-Ring Channel
- (2009) Pawel A. Osmulski et al. STRUCTURE
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- (2008) Antonia Busse et al. CANCER
- REGγ, a proteasome activator and beyond?
- (2008) I. Mao et al. CELLULAR AND MOLECULAR LIFE SCIENCES
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- (2008) Zhuo Zhang et al. EMBO JOURNAL
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- (2008) Alexander Visekruna et al. INFLAMMATORY BOWEL DISEASES
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- (2008) Thomas G. Gillette et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Rebecca Kirk et al. JOURNAL OF BIOLOGICAL CHEMISTRY
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- (2008) Aldrin V. Gomes et al. MOLECULAR & CELLULAR PROTEOMICS
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- (2008) Julius Rabl et al. MOLECULAR CELL
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- (2008) J. Blickwedehl et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Improved Structures of Full-Length p97, an AAA ATPase: Implications for Mechanisms of Nucleotide-Dependent Conformational Change
- (2008) Jason M. Davies et al. STRUCTURE
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