Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

Mixed Proteasomes Function To Increase Viral Peptide Diversity and Broaden Antiviral CD8+ T Cell Responses

(2013) D. Zanker et al.   JOURNAL OF IMMUNOLOGY

The unique functions of tissue-specific proteasomes

(2013) Andrea Kniepert et al.   TRENDS IN BIOCHEMICAL SCIENCES

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Immunoproteasome in Cancer and Neuropathologies: A New Therapeutic Target?

(2012) Elena Bellavista et al.   CURRENT PHARMACEUTICAL DESIGN

Why the Structure but Not the Activity of the Immunoproteasome Subunit Low Molecular Mass Polypeptide 2 Rescues Antigen Presentation

(2012) M. Basler et al.   JOURNAL OF IMMUNOLOGY

Distinct Proteasome Subpopulations in the Alveolar Space of Patients with the Acute Respiratory Distress Syndrome

(2012) S. U. Sixt et al.   MEDIATORS OF INFLAMMATION

Driving Forces of Proteasome-catalyzed Peptide Splicing in Yeast and Humans

(2012) Michele Mishto et al.   MOLECULAR & CELLULAR PROTEOMICS

Proteasome subtypes and the processing of tumor antigens: increasing antigenic diversity

(2011) Nathalie Vigneron et al.   CURRENT OPINION IN IMMUNOLOGY

Mice completely lacking immunoproteasomes show major changes in antigen presentation

(2011) Eleanor Z Kincaid et al.   NATURE IMMUNOLOGY

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope

(2011) Sylvain Cardinaud et al.   PLoS Pathogens

Optimization of a series of dipeptides with a P3 threonine residue as non-covalent inhibitors of the chymotrypsin-like activity of the human 20S proteasome

(2010) Christopher Blackburn et al.   BIOORGANIC & MEDICINAL CHEMISTRY LETTERS

Deletion of Immunoproteasome Subunits Imprints on the Transcriptome and Has a Broad Impact on Peptides Presented by Major Histocompatibility Complex I molecules

(2010) Danielle de Verteuil et al.   MOLECULAR & CELLULAR PROTEOMICS

Immunoproteasome LMP2 60HH Variant Alters MBP Epitope Generation and Reduces the Risk to Develop Multiple Sclerosis in Italian Female Population

(2010) Michele Mishto et al.   PLoS One

The 20S Proteasome Splicing Activity Discovered by SpliceMet

(2010) Juliane Liepe et al.   PLoS Computational Biology

Carfilzomib can induce tumor cell death through selective inhibition of the chymotrypsin-like activity of the proteasome

(2009) F. Parlati et al.   BLOOD

A selective inhibitor of the immunoproteasome subunit LMP7 blocks cytokine production and attenuates progression of experimental arthritis

(2009) Tony Muchamuel et al.   NATURE MEDICINE

Modeling the in Vitro 20S Proteasome Activity: The Effect of PA28–αβ and of the Sequence and Length of Polypeptides on the Degradation Kinetics

(2008) Michele Mishto et al.   JOURNAL OF MOLECULAR BIOLOGY