Foxn1-β5t transcriptional axis controls CD8+ T-cell production in the thymus

Dynamic spatio-temporal contribution of single β5t+ cortical epithelial precursors to the thymus medulla

(2016) Carlos E. Mayer et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

FOXN1 in thymus organogenesis and development

(2016) Harsh Jayesh Vaidya et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Foxn1 regulates key target genes essential for T cell development in postnatal thymic epithelial cells

(2016) Saulius Žuklys et al.   NATURE IMMUNOLOGY

Foxn1 Protein Expression in the Developing, Aging, and Regenerating Thymus

(2015) Immanuel Rode et al.   JOURNAL OF IMMUNOLOGY

TCR affinity for thymoproteasome-dependent positively selecting peptides conditions antigen responsiveness in CD8+ T cells

(2015) Kensuke Takada et al.   NATURE IMMUNOLOGY

Thymoproteasomes produce unique peptide motifs for positive selection of CD8+ T cells

(2015) Katsuhiro Sasaki et al.   Nature Communications

Adult Thymic Medullary Epithelium Is Maintained and Regenerated by Lineage-Restricted Cells Rather Than Bipotent Progenitors

(2015) Izumi Ohigashi et al.   Cell Reports

Electroporation enables the efficient mRNA delivery into the mouse zygotes and facilitates CRISPR/Cas9-based genome editing

(2015) Masakazu Hashimoto et al.   Scientific Reports

Checkpoints in the Development of Thymic Cortical Epithelial Cells

(2014) S. Shakib et al.   JOURNAL OF IMMUNOLOGY

DNA targeting specificity of RNA-guided Cas9 nucleases

(2013) Patrick D Hsu et al.   NATURE BIOTECHNOLOGY

High-throughput chromatin immunoprecipitation for genome-wide mapping of in vivo protein-DNA interactions and epigenomic states

(2013) Ronnie Blecher-Gonen et al.   Nature Protocols

Thymoproteasome subunit- 5T generates peptide-MHC complexes specialized for positive selection

(2013) Y. Xing et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Aire-expressing thymic medullary epithelial cells originate from  5t-expressing progenitor cells

(2013) I. Ohigashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Foxn1 Regulates Lineage Progression in Cortical and Medullary Thymic Epithelial Cells But Is Dispensable for Medullary Sublineage Divergence

(2011) Craig S. Nowell et al.   PLoS Genetics

Thymoproteasome Shapes Immunocompetent Repertoire of CD8+ T Cells

(2010) Takeshi Nitta et al.   IMMUNITY

Regulation of Zap70 Expression During Thymocyte Development Enables Temporal Separation of CD4 and CD8 Repertoire Selection at Different Signaling Thresholds

(2010) M. Saini et al.   Science Signaling

CD8+ T cell efficacy in vaccination and disease

(2008) Victor Appay et al.   NATURE MEDICINE