The central domain of yeast transcription factor Rpn4 facilitates degradation of reporter protein in human cells

Ubiquitin-independent proteasomal degradation

(2013) Jenny Erales et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Proteasome inhibition enhances resistance to DNA damage via upregulation of Rpn4-dependent DNA repair genes

(2013) Dmitry S. Karpov et al.   FEBS LETTERS

Nuclear Import Factor Srp1 and Its Associated Protein Sts1 Couple Ribosome-bound Nascent Polypeptides to Proteasomes for Cotranslational Degradation

(2013) Seung-Wook Ha et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The N-terminal domain of Rpn4 serves as a portable ubiquitin-independent degron and is recognized by specific 19S RP subunits

(2012) Seung-Wook Ha et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

DNA vaccine encoding α-fetoprotein fused with the ornithine decarboxylase degradation signal significantly suppresses the hepatocellular carcinoma growth in mice

(2012) A. V. Morozov et al.   MOLECULAR BIOLOGY

Direct Ubiquitin Independent Recognition and Degradation of a Folded Protein by the Eukaryotic Proteasomes-Origin of Intrinsic Degradation Signals

(2012) Amit Kumar Singh Gautam et al.   PLoS One

Targeted protein depletion in Saccharomyces cerevisiae by activation of a bidirectional degron

(2011) Marc Jungbluth et al.   BMC Systems Biology

Cooperation between an Intrinsically Disordered Region and a Helical Segment Is Required for Ubiquitin-independent Degradation by the Proteasome

(2011) Sandra P. Melo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Availability and canonical positioning of key amino acids of ornithine-decarboxylase degron is insufficient for alpha-fetoprotein degradation

(2011) A. V. Morozov et al.   MOLECULAR BIOLOGY

Escherichia coli Dam-methylase as a molecular tool for mapping binding sites of the yeast transcription factor Rpn4

(2011) D. S. Spasskaya et al.   MOLECULAR BIOLOGY

The N-end rule pathway and regulation by proteolysis

(2011) Alexander Varshavsky   PROTEIN SCIENCE

Functional dissection of the N-terminal degron of human thymidylate synthase

(2010) Sandra P. Melo et al.   BIOCHEMICAL JOURNAL

Proteasomal Degradation of Rpn4 in Saccharomyces cerevisiae Is Critical for Cell Viability Under Stressed Conditions

(2009) X. Wang et al.   GENETICS

Cytomegalovirus Promoter Up-regulation Is the Major Cause of Increased Protein Levels of Unstable Reporter Proteins after Treatment of Living Cells with Proteasome Inhibitors

(2009) Beatriz Alvarez-Castelao et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Proteasomes Can Degrade a Significant Proportion of Cellular Proteins Independent of Ubiquitination

(2009) James M. Baugh et al.   JOURNAL OF MOLECULAR BIOLOGY

Mapping of yeast Rpn4p transactivation domains

(2008) Karpov S. Dmitry et al.   FEBS LETTERS

Rpn4p is a positive and negative transcriptional regulator of the ubiquitin-proteasome system

(2008) D. S. Karpov et al.   MOLECULAR BIOLOGY

Diversity of degradation signals in the ubiquitin–proteasome system

(2008) Tommer Ravid et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY