Immunoproteasomes edit tumors, which then escapes immune recognition

The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognition

(2015) Martin Keller et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Inhibitory receptors as targets for cancer immunotherapy

(2015) Meghan E. Turnis et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Endoplasmic Reticulum Aminopeptidase 1 (ERAP1) Polymorphism Relevant to Inflammatory Disease Shapes the Peptidome of the Birdshot Chorioretinopathy-Associated HLA-A*29:02 Antigen

(2015) Carlos Alvarez-Navarro et al.   MOLECULAR & CELLULAR PROTEOMICS

Neoantigens in cancer immunotherapy

(2015) T. N. Schumacher et al.   SCIENCE

The future of immune checkpoint therapy

(2015) P. Sharma et al.   SCIENCE

Paradigms of protein degradation by the proteasome

(2014) Tomonao Inobe et al.   CURRENT OPINION IN STRUCTURAL BIOLOGY

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

(2014) Michele Mishto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Genomic and bioinformatic profiling of mutational neoepitopes reveals new rules to predict anticancer immunogenicity

(2014) Fei Duan et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Checkpoint blockade cancer immunotherapy targets tumour-specific mutant antigens

(2014) Matthew M. Gubin et al.   NATURE

Predicting immunogenic tumour mutations by combining mass spectrometry and exome sequencing

(2014) Mahesh Yadav et al.   NATURE

Impact of genomic polymorphisms on the repertoire of human MHC class I-associated peptides

(2014) Diana Paola Granados et al.   Nature Communications

Molecular Architecture and Assembly of the Eukaryotic Proteasome

(2013) Robert J. Tomko et al.   Annual Review of Biochemistry

Pathways of Antigen Processing

(2013) Janice S. Blum et al.   Annual Review of Immunology

Up-Regulation of PD-L1, IDO, and Tregs in the Melanoma Tumor Microenvironment Is Driven by CD8+ T Cells

(2013) S. Spranger et al.   Science Translational Medicine

Analysis of the Processing of Seven Human Tumor Antigens by Intermediate Proteasomes

(2012) B. Guillaume et al.   JOURNAL OF IMMUNOLOGY

CTL Escape Mediated by Proteasomal Destruction of an HIV-1 Cryptic Epitope

(2011) Sylvain Cardinaud et al.   PLoS Pathogens

Interferon   limits the effectiveness of melanoma peptide vaccines

(2010) H.-I. Cho et al.   BLOOD

Two abundant proteasome subtypes that uniquely process some antigens presented by HLA class I molecules

(2010) B. Guillaume et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Molecular Mechanisms of IFN-γ to Up-Regulate MHC Class I Antigen Processing and Presentation

(2009) Fang Zhou   INTERNATIONAL REVIEWS OF IMMUNOLOGY