PA28 modulates antigen processing and viral replication during coxsackievirus B3 infection

Inhibition of chymotryptic-like standard proteasome activity exacerbates doxorubicin-induced cytotoxicity in primary cardiomyocytes

(2016) Eva-Margarete Spur et al.   TOXICOLOGY

A Human Trypanosome Suppresses CD8+ T Cell Priming by Dendritic Cells through the Induction of Immune Regulatory CD4+ Foxp3+ T Cells

(2016) Jonatan Ersching et al.   PLoS Pathogens

Proteasome β5i Subunit Deficiency Affects Opsonin Synthesis and Aggravates Pneumococcal Pneumonia

(2016) Felicia Kirschner et al.   PLoS One

The immunoproteasome controls the availability of the cardioprotective pattern recognition molecule Pentraxin3

(2015) Anna Paeschke et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

The proteasome immunosubunits, PA28 and ER-aminopeptidase 1 protect melanoma cells from efficient MART-126-35-specific T-cell recognition

(2015) Martin Keller et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

PA28αβ Reduces Size and Increases Hydrophilicity of 20S Immunoproteasome Peptide Products

(2014) Mary Raule et al.   CHEMISTRY & BIOLOGY

Ubiquitin-Like Protein ISG15 (Interferon-Stimulated Gene of 15 kDa) in Host Defense Against Heart Failure in a Mouse Model of Virus-Induced Cardiomyopathy

(2014) Anna Rahnefeld et al.   CIRCULATION

Proteasome isoforms exhibit only quantitative differences in cleavage and epitope generation

(2014) Michele Mishto et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Removal of damaged proteins during ES cell fate specification requires the proteasome activator PA28

(2013) Malin Hernebring et al.   Scientific Reports

Cytokine-induced oxidative stress in cardiac inflammation and heart failure—how the ubiquitin proteasome system targets this vicious cycle

(2013) Antje Voigt et al.   Frontiers in Physiology

Immuno- and Constitutive Proteasome Crystal Structures Reveal Differences in Substrate and Inhibitor Specificity

(2012) Eva M. Huber et al.   CELL

Proteasome Dysfunction Mediates Obesity-Induced Endoplasmic Reticulum Stress and Insulin Resistance in the Liver

(2012) T. Otoda et al.   DIABETES

PA28 and the proteasome immunosubunits play a central and independent role in the production of MHC class I-binding peptides in vivo

(2011) Natascha de Graaf et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Mice completely lacking immunoproteasomes show major changes in antigen presentation

(2011) Eleanor Z Kincaid et al.   NATURE IMMUNOLOGY

Impairment of Immunoproteasome Function by β5i/LMP7 Subunit Deficiency Results in Severe Enterovirus Myocarditis

(2011) Elisa Opitz et al.   PLoS Pathogens

Immunoproteasomes Preserve Protein Homeostasis upon Interferon-Induced Oxidative Stress

(2010) Ulrike Seifert et al.   CELL

Enhancement of proteasome function by PA28α overexpression protects against oxidative stress

(2010) Jie Li et al.   FASEB JOURNAL

Differential Interferon Responses Enhance Viral Epitope Generation by Myocardial Immunoproteasomes in Murine Enterovirus Myocarditis

(2009) Sandra Jäkel et al.   AMERICAN JOURNAL OF PATHOLOGY

Generation of in silico predicted coxsackievirus B3-derived MHC class I epitopes by proteasomes

(2009) Antje Voigt et al.   AMINO ACIDS

Stressing the ubiquitin-proteasome system

(2009) N. P. Dantuma et al.   CARDIOVASCULAR RESEARCH

Viral Myocarditis

(2009) Toshitaka Yajima et al.   CIRCULATION

Hexameric assembly of the proteasomal ATPases is templated through their C termini

(2009) Soyeon Park et al.   NATURE

Proteasome inhibition attenuates coxsackievirus-induced myocardial damage in mice

(2008) Guang Gao et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Antitopes Define Preferential Proteasomal Cleavage Site Usage

(2008) Britta Strehl et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Enumeration and Functional Evaluation of Virus-Specific CD4+ and CD8+ T Cells in Lymphoid and Peripheral Sites of Coxsackievirus B3 Infection

(2008) C. C. Kemball et al.   JOURNAL OF VIROLOGY